@mastersthesis{MTMT:31390867, title = {A ghrelin-indukálta oxitocin elválasztás vizsgálata in vivo állatmodellben [Examination of the ghrelin-induced oxytocin release in an in vivo animal model]}, url = {https://m2.mtmt.hu/api/publication/31390867}, author = {Ménesi, Rudolf}, doi = {10.14232/phd.10412}, publisher = {SZTE}, unique-id = {31390867}, year = {2020} } @article{MTMT:30446615, title = {New Metabolic Influencer on Oxytocin Release: The Ghrelin}, url = {https://m2.mtmt.hu/api/publication/30446615}, author = {Szabó, Renáta and Ménesi, Rudolf and Molnár, Andor and Szalai, Zita and Daruka, Lejla and Tóth, Gábor and Gardi, János and Gálfi, Márta and Börzsei, Denise and Kupai, Krisztina and Juhász, Anna and Radács, Marianna and László, Ferenc and Varga, Csaba and Pósa, Anikó}, doi = {10.3390/molecules24040735}, journal-iso = {MOLECULES}, journal = {MOLECULES}, volume = {24}, unique-id = {30446615}, issn = {1420-3049}, year = {2019}, eissn = {1420-3049}, orcid-numbers = {Molnár, Andor/0000-0001-5980-2276; Szalai, Zita/0000-0002-8722-0211; Gálfi, Márta/0000-0002-7143-133X; Kupai, Krisztina/0000-0002-0644-1718; Radács, Marianna/0000-0003-0381-9276; Varga, Csaba/0000-0002-2678-665X; Pósa, Anikó/0000-0003-2167-2888} } @misc{MTMT:30445868, title = {A szabadidős testmozgás hatása az izoproterenol-indukálta miokardiális infarktus következményeire kísérletes menopauzában}, url = {https://m2.mtmt.hu/api/publication/30445868}, author = {Szabó, Renáta and Ménesi, Rudolf and Börzsei, Denise and Karácsonyi, Zoltán and Kupai, Krisztina and Veszelka, Médea and Török, Szilvia and Magyariné, Berkó Anikó and Varga, Csaba and Pósa, Anikó}, unique-id = {30445868}, year = {2018}, orcid-numbers = {Kupai, Krisztina/0000-0002-0644-1718; Magyariné, Berkó Anikó/0000-0002-1237-5745; Varga, Csaba/0000-0002-2678-665X; Pósa, Anikó/0000-0003-2167-2888} } @misc{MTMT:3080751, title = {The effects of aging and experimental menopause on the cardiac and inflammatory parameters}, url = {https://m2.mtmt.hu/api/publication/3080751}, author = {Szabó, Renáta and Csonka, Anett and Veszelka, Médea and Kupai, Krisztina and Magyariné, Berkó Anikó and Deim, Zoltán and Baráth, Zoltán Lajos and Ménesi, Rudolf and Pávó, Imre and Gyöngyösi, Mariann and László, Ferenc and Varga, Csaba and Pósa, Anikó}, unique-id = {3080751}, year = {2016}, orcid-numbers = {Kupai, Krisztina/0000-0002-0644-1718; Magyariné, Berkó Anikó/0000-0002-1237-5745; Deim, Zoltán/0000-0003-3925-5564; Baráth, Zoltán Lajos/0000-0003-0636-6313; Varga, Csaba/0000-0002-2678-665X; Pósa, Anikó/0000-0003-2167-2888} } @misc{MTMT:3080854, title = {Az ösztrogén-hiány következményeként kialakuló keringési és gyulladásos folyamatok vizsgálata patkány modellen}, url = {https://m2.mtmt.hu/api/publication/3080854}, author = {Szabó, Renáta and Kupai, Krisztina and Veszelka, Médea and Csonka, Anett and Török, Szilvia and Ménesi, Rudolf and Varga, Csaba and Pávó, Imre and Pósa, Anikó}, unique-id = {3080854}, year = {2015}, orcid-numbers = {Kupai, Krisztina/0000-0002-0644-1718; Varga, Csaba/0000-0002-2678-665X; Pósa, Anikó/0000-0003-2167-2888} } @article{MTMT:2934174, title = {Endogenous Estrogen-Mediated Heme Oxygenase Regulation in Experimental Menopause}, url = {https://m2.mtmt.hu/api/publication/2934174}, author = {Pósa, Anikó and Szabó, Renáta and Csonka, Anett and Veszelka, Médea and Magyariné, Berkó Anikó and Baráth, Zoltán Lajos and Ménesi, Rudolf and Pavo, Imre and Gyongyosi, Mariann and Laszlo, Ferenc and Kupai, Krisztina and Varga, Csaba}, doi = {10.1155/2015/429713}, journal-iso = {OXID MED CELL LONGEV}, journal = {OXIDATIVE MEDICINE AND CELLULAR LONGEVITY}, volume = {2015}, unique-id = {2934174}, issn = {1942-0900}, abstract = {Estrogen deficiency is one of the main causes of age-associated diseases in the cardiovascular system. Female Wistar rats were divided into four experimental groups: pharmacologically ovariectomized, surgically ovariectomized, and 24-month-old intact aging animals were compared with a control group. The activity and expression of heme oxygenases (HO) in the cardiac left ventricle, the concentrations of cardiac interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-alpha), the myeloperoxidase (MPO) activity in the cardiac left ventricle, and the effects of heme oxygenase blockade (by 24-hour and 1-hour pretreatment with tin-protoporphyrin IX, SnPP) on the epinephrine and phentolamine-induced electrocardiogram ST segment changes in vivo were investigated. The cardiac HO activity and the expression of HO-1 and HO-2 were significantly decreased in the aged rats and after ovariectomy. Estrogen depletion was accompanied by significant increases in the expression of IL-6 and TNF-alpha. The aged and ovariectomized animals exhibited a significantly elevated MPO activity and a significant ST segment depression. After pretreatment with SnPP augmented ST segment changes were determined. These findings demonstrate that the sensitivity to cardiac ischemia in estrogen depletion models is associated with suppression of the activity and expression of the HO system and increases in the secretion of proinflammatory cytokines and biomarkers.}, year = {2015}, eissn = {1942-0994}, orcid-numbers = {Pósa, Anikó/0000-0003-2167-2888; Magyariné, Berkó Anikó/0000-0002-1237-5745; Baráth, Zoltán Lajos/0000-0003-0636-6313; Kupai, Krisztina/0000-0002-0644-1718; Varga, Csaba/0000-0002-2678-665X} } @article{MTMT:2788926, title = {Cardioprotective effects of voluntary exercise in a rat model: role of matrix metalloproteinase-2}, url = {https://m2.mtmt.hu/api/publication/2788926}, author = {Pósa, Anikó and Szabó, Renáta and Kupai, Krisztina and Baráth, Zoltán Lajos and Szalai, Zita and Csonka, Anett and Veszelka, Médea and Gyöngyösi, Mariann and Radák, Zsolt and Ménesi, Rudolf and Pávó, Imre and Magyariné, Berkó Anikó and Varga, Csaba}, doi = {10.1155/2015/876805}, journal-iso = {OXID MED CELL LONGEV}, journal = {OXIDATIVE MEDICINE AND CELLULAR LONGEVITY}, volume = {2015}, unique-id = {2788926}, issn = {1942-0900}, year = {2015}, eissn = {1942-0994}, orcid-numbers = {Pósa, Anikó/0000-0003-2167-2888; Kupai, Krisztina/0000-0002-0644-1718; Baráth, Zoltán Lajos/0000-0003-0636-6313; Szalai, Zita/0000-0002-8722-0211; Radák, Zsolt/0000-0003-1297-6804; Magyariné, Berkó Anikó/0000-0002-1237-5745; Varga, Csaba/0000-0002-2678-665X} } @article{MTMT:2473505, title = {Sexual dimorphism of cardiovascular ischemia susceptibility is mediated by heme oxygenase}, url = {https://m2.mtmt.hu/api/publication/2473505}, author = {Pósa, Anikó and Kupai, Krisztina and Ménesi, Rudolf and Szalai, Zita and Szabó, Renáta and Pintér, Zoltán and Pálfi, György and Gyöngyösi, M and Magyariné, Berkó Anikó and Pávó, I and Varga, Csaba}, doi = {10.1155/2013/521563}, journal-iso = {OXID MED CELL LONGEV}, journal = {OXIDATIVE MEDICINE AND CELLULAR LONGEVITY}, volume = {2013}, unique-id = {2473505}, issn = {1942-0900}, abstract = {We investigated the gender differences in heme-oxygenase (HO) enzyme, which produces endogenous vascular protective carbon monoxide (CO). We studied (1) the activity and expression of HO enzymes in the left ventricle (LV) and aorta, (2) basal increase in basal blood pressure provoked by arginine vasopressine (AVP) in vivo, (3) the heart perfusion induced by AVP, (4) the ST segment depression provoked by adrenaline and 30 seconds later phentolamine, and (5) the aorta ring contraction induced by AVP in female and male Wistar rats. We found that HO activity and the expression of HO-1 and HO-2 were increased in female rat aorta and LV. We demonstrated that the basal blood pressure and administration of AVP provoked blood pressure response are increased in the males; the female myocardium was less sensitive towards angina. Both differences could be aggravated by the inhibition of HO. The aorta rings were more susceptible towards vasoconstriction by AVP in males; isolated heart perfusion decrease was higher in males. The HO inhibition aggravated the heart perfusion in both sexes. In conclusion, the increased HO activity and expression in females might play a role in the sexual dimorphism of cardiovascular ischemia susceptibility during the reproductive age. © 2013 Anikó Pósa et al.}, keywords = {Blood Pressure; Female; Male; ENZYMES; ARTICLE; VASOCONSTRICTION; controlled study; nonhuman; animal model; animal experiment; Aorta; sex difference; phentolamine; argipressin; enzyme activity; protein expression; carbon monoxide; adrenalin; in vivo study; heart muscle ischemia; amino acids; isolated heart; heart perfusion; Porphyrins; HEME OXYGENASE; Blood Vessels; heme oxygenase 1; vascular ring; gender differences; heart left ventricle; ST segment depression; sexual dimorphism; heme oxygenase 2; aorta constriction; Left ventricles; Ring contraction; Pressure response; Heme oxygenases; Cardiovascular ischemia; rat}, year = {2013}, eissn = {1942-0994}, orcid-numbers = {Pósa, Anikó/0000-0003-2167-2888; Kupai, Krisztina/0000-0002-0644-1718; Szalai, Zita/0000-0002-8722-0211; Magyariné, Berkó Anikó/0000-0002-1237-5745; Varga, Csaba/0000-0002-2678-665X} } @CONFERENCE{MTMT:2186611, title = {A rekreatív testmozgás hatása a hem-oxigenáz, nitrogénmonoxid-szintáz és matrix metalloproteázok aktivitására és expressziójára patkány kardiovaszkuláris rendszerben}, url = {https://m2.mtmt.hu/api/publication/2186611}, author = {Szabó, Renáta and Pósa, Anikó and Magyariné, Berkó Anikó and Szalai, Zita and Ménesi, Rudolf and Varga, Csaba}, booktitle = {A Magyar Élettani Társaság, a Magyar Anatómusok Társasága, a Magyar Biofizikai Társaság és a Magyar Mikrocirkulációs és Vaszkuláris Biológiai Társaság Kongresszusa}, unique-id = {2186611}, year = {2012}, pages = {33-33}, orcid-numbers = {Pósa, Anikó/0000-0003-2167-2888; Magyariné, Berkó Anikó/0000-0002-1237-5745; Szalai, Zita/0000-0002-8722-0211; Varga, Csaba/0000-0002-2678-665X} } @CONFERENCE{MTMT:1526992, title = {Sodium sensitive hypertension, the effectiveness of salt restriction.}, url = {https://m2.mtmt.hu/api/publication/1526992}, author = {Ménesi, Rudolf and Lelovics, Zsuzsanna and Kovács, Ildikó and László, Ferenc}, booktitle = {Abstracts of Croatian–Hungarian Young Investigator Conference}, unique-id = {1526992}, year = {2010}, pages = {101-101} }