@article{MTMT:33688118,
	title = {Role of interleukin-6 and interleukin-10 in morphological and functional changes of the blood–brain barrier in hypertriglyceridemia},
	url = {https://m2.mtmt.hu/api/publication/33688118},
	author = {Barabási, Beáta and Barna, Lilla and Santa Maria, Anaraquel and Harazin, András and Molnár, Réka and Kincses, András and Vigh, Judit Piroska and Dukay, Brigitta and Sántha, Miklós and Tóth, Erzsébet Melinda and Walter, Fruzsina and Deli, Mária Anna and Hoyk, Zsófia},
	doi = {10.1186/s12987-023-00418-3},
	journal-iso = {FLUIDS BARRIERS CNS},
	journal = {FLUIDS AND BARRIERS OF THE CNS},
	volume = {20},
	unique-id = {33688118},
	issn = {2045-8118},
	year = {2023},
	eissn = {2045-8118},
	orcid-numbers = {Santa Maria, Anaraquel/0000-0003-3505-5477; Harazin, András/0000-0002-0904-5606; Molnár, Réka/0000-0002-3128-825X; Walter, Fruzsina/0000-0001-8145-2823; Deli, Mária Anna/0000-0001-6084-6524}
}

@article{MTMT:31807147,
	title = {Neuroinflammatory processes are augmented in mice overexpressing human heat-shock protein B1 following ethanol-induced brain injury},
	url = {https://m2.mtmt.hu/api/publication/31807147},
	author = {Dukay, Brigitta and Walter, Fruzsina and Vigh, Judit Piroska and Barabási, Beáta and Hajdu, Petra and Balassa, Tamás and Migh, Ede and Kincses, András and Hoyk, Zsófia and Szögi, Titanilla and Borbély, Emőke and Csoboz, Bálint and Horváth, Péter and Fülöp, Lívia and Penke, Botond and Vigh, László and Deli, Mária Anna and Sántha, Miklós and Tóth, Erzsébet Melinda},
	doi = {10.1186/s12974-020-02070-2},
	journal-iso = {J NEUROINFLAMM},
	journal = {JOURNAL OF NEUROINFLAMMATION},
	volume = {18},
	unique-id = {31807147},
	year = {2021},
	eissn = {1742-2094},
	orcid-numbers = {Walter, Fruzsina/0000-0001-8145-2823; Szögi, Titanilla/0000-0002-9854-7340; Fülöp, Lívia/0000-0002-8010-0129; Penke, Botond/0000-0003-0938-0567; Deli, Mária Anna/0000-0001-6084-6524}
}

@misc{MTMT:31432297,
	title = {IL-6 and IL-10 induced changes in brain endothelium in a mouse model of human atherosclerosis},
	url = {https://m2.mtmt.hu/api/publication/31432297},
	author = {Barabási, Beáta and Barna, L and Harazin, A and Toth, M and Dukay, B and Santha, M and Hoyk, Z and Deli, M},
	unique-id = {31432297},
	year = {2019}
}

@misc{MTMT:31432611,
	title = {P-glycoprotein expressional changes in brain microvessel endothelial cells related to neuroinflammation},
	url = {https://m2.mtmt.hu/api/publication/31432611},
	author = {Hoyk, Z and Barabási, Beáta and Barna, L and Harazin, A and Vigh, J and Toth, M and Dukay, B and Santha, M},
	unique-id = {31432611},
	year = {2018}
}

@misc{MTMT:30725306,
	title = {P-glycoprotein expressional changes in brain capillary endothelial cells related to neuroinflammation},
	url = {https://m2.mtmt.hu/api/publication/30725306},
	author = {Barabási, Beáta and Barna, L and Harazin, A and Vigh, J and Toth, M and Dukay, B and Santha, M and Hoyk, Z and Deli, MA},
	unique-id = {30725306},
	year = {2018}
}

@article{MTMT:30312141,
	title = {Cerebrovascular Pathology in Hypertriglyceridemic APOB-100 Transgenic Mice},
	url = {https://m2.mtmt.hu/api/publication/30312141},
	author = {Hoyk, Zsófia and Tóth, Erzsébet Melinda and Lénárt, Nikolett and Nagy, Dóra and Dukay, Brigitta and Csefová, Alexandra and Zvara, Ágnes and Seprényi, György and Kincses, András and Walter, Fruzsina and Veszelka, Szilvia and Vigh, Judit Piroska and Barabási, Beáta and Harazin, András and Kittel, Ágnes and Puskás, László and Penke, Botond and Vigh, László and Deli, Mária Anna and Sántha, Miklós},
	doi = {10.3389/fncel.2018.00380},
	journal-iso = {FRONT CELL NEUROSCI},
	journal = {FRONTIERS IN CELLULAR NEUROSCIENCE},
	volume = {12},
	unique-id = {30312141},
	issn = {1662-5102},
	abstract = {Hypertriglyceridemia is not only a serious risk factor in the development of cardiovascular diseases, but it is linked to neurodegeneration, too. Previously, we generated transgenic mice overexpressing the human APOB-100 protein, a mouse model of human atherosclerosis. In this model we observed high plasma levels of triglycerides, oxidative stress, tau hyperphosphorylation, synaptic dysfunction, cognitive impairment, increased neural apoptosis and neurodegeneration. Neurovascular dysfunction is recognized as a key factor in the development of neurodegenerative diseases, but the cellular and molecular events linking cerebrovascular pathology and neurodegeneration are not fully understood. Our aim was to study cerebrovascular changes in APOB-100 transgenic mice. We described the kinetics of the development of chronic hypertriglyceridemia in the transgenic animals. Increased blood-brain barrier permeability was found in the hippocampus of APOB-100 transgenic mice which was accompanied by structural changes. Using transmission electron microscopy, we detected changes in the brain capillary endothelial tight junction structure and edematous swelling of astrocyte endfeet. In brain microvessels isolated from APOB-100 transgenic animals increased Lox-1, Aqp4, and decreased Meox-2, Mfsd2a, Abcb1a, Lrp2, Glut-1, Nos2, Nos3, Vim, and in transgenic brains reduced Cdh2 and Gfap-σ gene expressions were measured using quantitative real-time PCR. We confirmed the decreased P-glycoprotein (ABCB1) and vimentin expression related to the neurovascular unit by immunostaining in transgenic brain sections using confocal microscopy. We conclude that in chronic hypertriglyceridemic APOB-100 transgenic mice both functional and morphological cerebrovascular pathology can be observed, and this animal model could be a useful tool to study the link between cerebrovascular pathology and neurodegeneration.},
	keywords = {P-GLYCOPROTEIN; Blood-Brain Barrier; HYPERTRIGLYCERIDEMIA; tight junction; astroglia; Apolipoprotein B-100; Brain endothelial cell; cerebrovascular pathology},
	year = {2018},
	eissn = {1662-5102},
	orcid-numbers = {Lénárt, Nikolett/0000-0002-7456-949X; Walter, Fruzsina/0000-0001-8145-2823; Harazin, András/0000-0002-0904-5606; Penke, Botond/0000-0003-0938-0567; Deli, Mária Anna/0000-0001-6084-6524}
}

@article{MTMT:3013488,
	title = {Effect of axotomy and 17beta-estradiol on P2X7 receptor expression pattern in the hypoglossal nucleus of ovariectomized mice.},
	url = {https://m2.mtmt.hu/api/publication/3013488},
	author = {Barabási, Beáta and Csondor, A and Martin-Pozas, T and Sanchez, AM and Antalffy, G and Siklós, László and Gomez-Pinedo, U and Párducz, Árpád and Hoyk, Zsófia},
	doi = {10.1016/j.neuroscience.2016.01.049},
	journal-iso = {NEUROSCIENCE},
	journal = {NEUROSCIENCE},
	volume = {319},
	unique-id = {3013488},
	issn = {0306-4522},
	abstract = {The objective of the study was to examine whether axotomy and 17beta-estradiol affects P2X7 receptor expression and distribution in the hypoglossal nucleus. The left hypoglossal nerve of ovariectomized mice was cut and animals received a single injection of 17beta-estradiol (25mug/100 g b. w. in 20% (2- hydroxypropyl) - beta- cyclodextrin) or vehicle one hour after axotomy. Mice were sacrificed on day 4 following surgery. The area fraction of P2X7 receptor immunoreactive structures and of CD11b immunolabeled microglia, P2X7 protein concentration, and the immunoreactivity pattern of estrogen receptor alpha / beta were analyzed on both sides of the hypoglossal nucleus. Following axotomy the area fraction of P2X7 immunoreactive neurons showed a decreasing tendency, while the area fraction of P2X7 immunolabeled microglia increased significantly on the axotomized side compared with the control side in mice injected with vehicle. In animals treated with 17beta-estradiol the decrease in area fraction of neural and the increase in area fraction of microglial P2X7 immunostaining on the axotomized side were significantly enhanced compared with animals injected with vehicle. The P2X7 immunoreactivity pattern on the control side of the nucleus remained unchanged after 17beta-estradiol injection. Semi-quantitative Western blots revealed no significant difference in P2X7 protein concentration comparing the axotomized side with the control side in either experimental group. The CD11b immunoreactive microglia area fraction increased significantly following axotomy, but was not affected by 17beta-estradiol. Neither estrogen receptor alpha, nor beta colocalized with CD11b. Our results suggest that axotomy induces cell-type specific changes in P2X7 receptor expression, which may be directly regulated by 17beta-estradiol through estrogen receptor alpha or beta in neurons, but not in activated microglia.},
	year = {2016},
	eissn = {1873-7544},
	pages = {107-115}
}

@misc{MTMT:30725313,
	title = {17β-estradiol augments axotomy-induced cell-type specific changes in P2X7 receptor expression in the mouse hypoglossal nucleus},
	url = {https://m2.mtmt.hu/api/publication/30725313},
	author = {Hoyk, Z and Barabási, Beáta and Csondor, A and Martin-Pozas, T and Pulupa, Sanchez AM and Siklos, L and Gomez-Pinedo, U and Parducz, A},
	unique-id = {30725313},
	year = {2015}
}

@article{MTMT:2921753,
	title = {17 beta-estradiol augments axotomy-induced cell-type specific changes in P2X7 receptor expression in the mouse hypoglossal nucleus},
	url = {https://m2.mtmt.hu/api/publication/2921753},
	author = {Hoyk, Zsófia and Barabási, Beáta and Csondor, A and Martin-Pozas, T and Sanchez, AMP and Siklos, L and Gomez-Pinedo, U and Parducz, A},
	journal-iso = {GLIA},
	journal = {GLIA},
	volume = {63},
	unique-id = {2921753},
	issn = {0894-1491},
	year = {2015},
	eissn = {1098-1136},
	pages = {E419-E419}
}

@misc{MTMT:30725323,
	title = {Estrogen effect on the immune functions of microglia in the oculomotor and hypoglossal nucleus of mice following peripheral axotomy},
	url = {https://m2.mtmt.hu/api/publication/30725323},
	author = {Csondor, A and Barabási, Beáta and Siklos, L and Parducz, A and Hoyk, Z},
	unique-id = {30725323},
	year = {2014}
}