@article{MTMT:34483761, title = {Új katalitikus rendszerek alkalmazása aszimmetrikus Michael-addíciókban maleimidekre}, url = {https://m2.mtmt.hu/api/publication/34483761}, author = {Kozma, Viktória and Szőllősi, György}, doi = {10.24100/MKF.2023.03-04.139}, journal-iso = {MAGY KÉM FOLY KÉM KÖZL}, journal = {MAGYAR KÉMIAI FOLYÓIRAT - KÉMIAI KÖZLEMÉNYEK (1997-)}, volume = {129}, unique-id = {34483761}, issn = {1418-9933}, year = {2023}, eissn = {1418-8600}, pages = {139-146}, orcid-numbers = {Szőllősi, György/0000-0003-4418-9530} } @mastersthesis{MTMT:34121002, title = {Új katalitikus rendszerek alkalmazása aszimmetrikus Michael-addíciókban maleimidekre [Application of new catalytic systems in asymmetric Michael additions to maleimides]}, url = {https://m2.mtmt.hu/api/publication/34121002}, author = {Kozma, Viktória}, doi = {10.14232/phd.11305}, publisher = {Universití of Szeged}, unique-id = {34121002}, year = {2022} } @article{MTMT:33080561, title = {β-Amino Acid Organocatalysts in the Asymmetric Michael Addition of Isobutyraldehyde to N-Substituted Maleimides}, url = {https://m2.mtmt.hu/api/publication/33080561}, author = {Kozma, Viktória and Szakonyi, Zsolt and Szőllősi, György}, doi = {10.3390/catal12090992}, journal-iso = {CATALYSTS}, journal = {CATALYSTS}, volume = {12}, unique-id = {33080561}, abstract = {Asymmetric Michael additions of carbonyl compounds to N-substituted maleimides are among the most convenient reactions to prepare optically pure succinimide building blocks. Although a few β-amino acids were found to be highly efficient organocatalysts in the addition of α-branched aldehydes, the effect of their structure on the results of these reactions has not yet been investigated. In the present study, we disclose several unexpected and interesting structural effects of aliphatic and cycloaliphatic β-amino acids obtained in the enantioselective conjugate addition of isobutyraldehyde to N-benzylmaleimide. The dependence of the sense of the enantioselectivity on the bulkiness of the substituent on the β-carbon atom, the beneficial spatial arrangements of the functional groups in cis isomers with cyclohexane scaffold and the inversion of the enantioselectivity depending on the absence of a base additive observed with some trans isomers are unprecedented findings. The minor influence of the nitrogen substituent of the maleimide ring on both the reaction rate and the enantioselectivity was also evidenced using alicyclic β-amino acid prepared from an easily available terpene derivative.}, year = {2022}, eissn = {2073-4344}, orcid-numbers = {Szakonyi, Zsolt/0000-0003-2432-8409; Szőllősi, György/0000-0003-4418-9530} } @article{MTMT:32936771, title = {Enantioselective Michael addition of aldehydes to maleimides catalysed by surface-adsorbed natural amino acids}, url = {https://m2.mtmt.hu/api/publication/32936771}, author = {Kozma, Viktória and Szőllősi, György}, doi = {10.1039/d2cy00545j}, journal-iso = {CATAL SCIENCE & TECHNOLOGY}, journal = {CATALYSIS SCIENCE & TECHNOLOGY}, volume = {12}, unique-id = {32936771}, issn = {2044-4753}, abstract = {Asymmetric Michael addition of carbonyl compounds to N-substituted maleimides is an important method for obtaining optically pure succinimides, which are important chiral fine chemical intermediates. Environmentally friendly and sustainable procedures require the use of a heterogeneous, recyclable catalyst obtained from natural chirality sources and cheap auxiliaries. Here we report the application of in situ formed chiral inorganic-organic hybrid catalysts using amino acids such as l-phenylalanine and clay minerals or alumina, which were highly active and provided excellent enantioselectivities, up to 99%, in the addition of aldehydes to a large variety of N-substituted maleimides. Examinations indicated the occurrence of the asymmetric reaction on the surface of the recyclable solid hybrid materials. The catalytic materials were examined by thermogravimetry, XRD, FT-IR and Raman spectroscopy, SEM and adsorption experiments. Results of these methods showed that the amino acid is deposited as surface crystallites or intercalated in the layered cation exchangers, which both function as a supply of the chirality source, whereas the reactions are catalysed by the chiral compounds adsorbed on the surface. This catalytic system was used to conveniently prepare chiral succinimides at the gram scale, easily purified by crystallization. Accordingly, these chiral hybrid materials are convenient heterogeneous catalysts for obtaining valuable compounds in high optical purities using natural chirality sources, inorganic solids and ethyl acetate, a green organic solvent.}, year = {2022}, eissn = {2044-4761}, pages = {4709-4726}, orcid-numbers = {Szőllősi, György/0000-0003-4418-9530} } @article{MTMT:32555761, title = {Conjugate addition of 1,3-dicarbonyl compounds to maleimides using bifunctional primary amine‒(thio)phosphoramide organocatalysts}, url = {https://m2.mtmt.hu/api/publication/32555761}, author = {Kozma, Viktória and Szőllősi, György}, doi = {10.1016/j.mcat.2021.112089}, journal-iso = {MOL CATAL}, journal = {MOLECULAR CATALYSIS}, volume = {518}, unique-id = {32555761}, issn = {2468-8231}, year = {2022}, eissn = {2468-8274}, orcid-numbers = {Szőllősi, György/0000-0003-4418-9530} } @inproceedings{MTMT:32525198, title = {NATURAL CHIRAL CATALYSTS ON SOLID SURFACES USED IN MICHAEL ADDITION TO MALEIMIDES}, url = {https://m2.mtmt.hu/api/publication/32525198}, author = {Kozma, Viktória and Szőllősi, György}, booktitle = {Proceedings of the 27th International Symposium on Analytical and Environmental Problems}, unique-id = {32525198}, year = {2021}, pages = {193-197}, orcid-numbers = {Szőllősi, György/0000-0003-4418-9530} } @inproceedings{MTMT:31719676, title = {Phosphoramide chiral catalysts for environmentally friendly asymmetric organocatalytic processes}, url = {https://m2.mtmt.hu/api/publication/31719676}, author = {Kozma, Viktória and Szőllősi, György}, booktitle = {Proceedings of the 26th International Symposium on Analytical and Environmental Problems}, unique-id = {31719676}, year = {2020}, pages = {35-39}, orcid-numbers = {Szőllősi, György/0000-0003-4418-9530} } @article{MTMT:31346249, title = {1,2‐Diamine‐Derived (thio)Phosphoramide Organocatalysts in Asymmetric Michael Additions}, url = {https://m2.mtmt.hu/api/publication/31346249}, author = {Kozma, Viktória and Fülöp, Ferenc and Szőllősi, György}, doi = {10.1002/adsc.202000335}, journal-iso = {ADV SYNTH CATAL}, journal = {ADVANCED SYNTHESIS & CATALYSIS}, volume = {362}, unique-id = {31346249}, issn = {1615-4150}, year = {2020}, eissn = {1615-4169}, pages = {2444-2458}, orcid-numbers = {Fülöp, Ferenc/0000-0003-1066-5287; Szőllősi, György/0000-0003-4418-9530} } @article{MTMT:30849372, title = {β-Isocupreidinate-CaAl-layered double hydroxide composites-heterogenized catalysts for asymmetric Michael addition}, url = {https://m2.mtmt.hu/api/publication/30849372}, author = {Varga, Gábor and Kozma, Viktória and Kolcsár, Vanessza Judit and Kukovecz, Ákos and Kónya, Zoltán and Sipos, Pál Miklós and Pálinkó, István and Szőllősi, György}, doi = {10.1016/j.mcat.2019.110675}, journal-iso = {MOL CATAL}, journal = {MOLECULAR CATALYSIS}, volume = {482}, unique-id = {30849372}, issn = {2468-8231}, year = {2020}, eissn = {2468-8274}, orcid-numbers = {Varga, Gábor/0000-0002-7131-1629; Kukovecz, Ákos/0000-0003-0716-9557; Kónya, Zoltán/0000-0002-9406-8596; Sipos, Pál Miklós/0000-0003-1407-0950; Pálinkó, István/0000-0002-8508-309X; Szőllősi, György/0000-0003-4418-9530} } @inproceedings{MTMT:30856152, title = {Asymmetric Michael-additions catalyzed by environmentally benign heterogeneous chiral 1,2-diamine derivatives}, url = {https://m2.mtmt.hu/api/publication/30856152}, author = {Kozma, Viktória and Szőllősi, György}, booktitle = {Proceedings of the 25th International Symposium on Analytical and Environmental Problems}, unique-id = {30856152}, year = {2019}, pages = {342-344}, orcid-numbers = {Szőllősi, György/0000-0003-4418-9530} }