@article{MTMT:33754180, title = {Hungarian Linguistic, Cross-Cultural and Age Adaptation of Transition Specific Questionnaires in Patients with Inflammatory Bowel Disease}, url = {https://m2.mtmt.hu/api/publication/33754180}, author = {Dohos, Dóra and Váradi, Alex and Borbásné Farkas, Kornélia and Erős, Adrienn and Müller, Katalin Eszter and Karoliny, Anna and Gombos, Eszter and Nemes, Éva and Vass, Noémi and Tárnok, András and Hegyi, Péter and Sarlós, Patrícia}, doi = {10.3390/children10040711}, journal-iso = {CHILDREN-BASEL}, journal = {CHILDREN (BASEL)}, volume = {10}, unique-id = {33754180}, abstract = {Objective: In the TRANS–IBD clinical trial, the outcomes are measured with selected validated questionnaires. Cross-cultural and age adaptations of the Self-Efficacy Scale for adolescents and young adults (IBD–SES), the Transition Readiness Assessment Questionnaire (TRAQ), and the Self-Management and Transition Readiness Questionnaire (STARx) were performed. Methods: Linguistic and cultural adaptation was carried out with the usage of reliability coefficients (Cronbach’s α coefficients, Spearman’s rank correlation), and with confirmatory factor analysis (CFA; root Mean Square Error of Approximation [RMSEA], Comparative Fit Index [CFI], and Tucker-Lewis Index [TLI]). Results: 112 adolescents participated in the study (45.5% male, mean age 17 ± 1.98 years). CFA was acceptable in the IBD–SES and the TRAQ. Internal consistency was acceptable in IBD–SES and good in TRAQ (0.729; 0.865, respectively). Test–retest reliability was good in IBD–SES, but below the acceptable threshold in TRAQ (ρ = 0.819; ρ = 0.034). In STARx tools, RMSEA showed poor fit values, CFI and TLI were below acceptable fit values, and internal consistency was not satisfied (0.415; 0.693, respectively), while test–retest reliabilities were acceptable (ρ = 0.787; ρ = 0.788, respectively). Conclusions: Cross-cultural, age-specific adaptation was successfully completed with IBD–SES and TRAQ. Those are comparable to the original validated versions. The adaption of the STARx tools was not successful.}, year = {2023}, eissn = {2227-9067}, orcid-numbers = {Váradi, Alex/0000-0001-8229-6340; Borbásné Farkas, Kornélia/0000-0002-5349-6527; Müller, Katalin Eszter/0000-0001-5355-4224; Tárnok, András/0000-0001-7019-2755; Hegyi, Péter/0000-0003-0399-7259; Sarlós, Patrícia/0000-0002-5086-9455} } @article{MTMT:33068977, title = {Hungarian Linguistic, Cross-Cultural, and Age Adaptation of the Patient Satisfaction with Health Care in Inflammatory Bowel Disease Questionnaire (CACHE) and the Medication Adherence Report Scale (MARS).}, url = {https://m2.mtmt.hu/api/publication/33068977}, author = {Dohos, Dóra and Váradi, Alex and Borbásné Farkas, Kornélia and Erős, Adrienn and Párniczky, Andrea and Schäfer, Eszter and Kosaras, Éva and Czelecz, Judit and Hegyi, Péter and Sarlós, Patrícia}, doi = {10.3390/children9081143}, journal-iso = {CHILDREN-BASEL}, journal = {CHILDREN (BASEL)}, volume = {9}, unique-id = {33068977}, abstract = {The TRANS-IBD study examines the superiority of joint transition visits, with drug adherence and patient satisfaction among the outcome measures. Our aim was a cross-cultural, age- and disease-specific adaptation of the 'Medication Adherence Rating Scale' (MARS) and 'Patient satisfaction with health care in inflammatory bowel disease questionnaire' (CACHE) questionnaires in patients with inflammatory bowel disease (IBD).Linguistic and cultural adaptation using test and re-test procedures were performed. Internal consistency with Cronbach's α coefficients, confirmatory factor analyses with root Mean Square Error of Approximation (RMSEA), Comparative Fit Index (CFI), and Tucker-Lewis Index (TLI) were determined.A total of 122 adolescents and 164 adults completed the questionnaires (47.5% male, mean age 17 ± 1; and 29.3% male, mean age 38 ± 11, respectively). In the MARS questionnaire, Cronbach's α scores were found good in adolescents (0.864) and acceptable in adults (0.790), while in the CACHE questionnaire, scores were rated as excellent in both populations (0.906 and 0.945, respectively). The test-retest reliabilities were satisfactory in both groups (MARS questionnaire: r = 0.814 and r = 0.780, CACHE questionnaire: r = 0.892 and r = 0.898, respectively). RMSEA showed poor fit values in the MARS questionnaire and reasonable fit values in the CAHCE questionnaire, CFI and TLI had statistically acceptable results.Age-and disease-specific Hungarian versions of the questionnaires were developed, which are appropriate tools for TRANS-IBD RCT and daily IBD care.}, keywords = {Inflammatory bowel disease; Mars; ADAPTATION; questionnaire; cache; TRANS-IBD}, year = {2022}, eissn = {2227-9067}, orcid-numbers = {Váradi, Alex/0000-0001-8229-6340; Borbásné Farkas, Kornélia/0000-0002-5349-6527; Hegyi, Péter/0000-0003-0399-7259; Sarlós, Patrícia/0000-0002-5086-9455} } @article{MTMT:32150100, title = {Közös felelősség a gyulladásos bélbetegség diagnosztikájában és kezelésében. Mikor utaljuk a gyulladásos bélbetegséggel kezelt beteget biológiai terápiás centrumba? = Shared responsibility in the diagnosis and treatment of inflammatory bowel disease : When to refer a patient with inflammatory bowel disease to a biological therapy center?}, url = {https://m2.mtmt.hu/api/publication/32150100}, author = {Dohos, Dóra and Erős, Adrienn and Szemes, Kata and Sarlós, Patrícia}, doi = {10.1556/650.2021.32182}, journal-iso = {ORV HETIL}, journal = {ORVOSI HETILAP}, volume = {162}, unique-id = {32150100}, issn = {0030-6002}, abstract = {Összefoglaló. Az idült betegségek, köztük a gyulladásos bélbetegség kezelése összetett feladat, amely a megfelelő technikai feltételek mellett naprakész szaktudással és tapasztalattal rendelkező egészségügyi személyzet együttműködését igényli. Célunk a gyulladásos bélbetegség ellátásának célirányos összegzése volt. Kiemelten foglalkoztunk a korai diagnosztika és szakorvoshoz utalás kérdésével, a korszerű ellátáshoz szükséges, személyre szabott terápia és a célértékre történő kezelés, valamint a biológiai terápiás centrumba utalás szükségességével. Részleteztük továbbá a kompetens és felelősségteljes gondozás ellátószintjeit, és bemutattuk az ellátásban együttműködő multidiszciplináris csoport felépítését is. Az összefoglaló közleményhez a nemzetközi irodalmat és a hazai terápiás protokollokat tekintettük át. A krónikus betegségek gondozásában elengedhetetlen a társszakmák együttműködése. A betegség kezelésében fontos a folyamatosan változó ajánlások, protokollok ismerete és a kompetenciaszintek elfogadása a beteg megfelelő életminőségének elérése és a szövődmények csökkentése céljából. Orv Hetil. 2021; 162(33): 1311-1317. Summary. The treatment of chronic diseases, including inflammatory bowel disease, is a complex task that requires the collaboration of health professionals with up-to-date expertise and experience under the appropriate technical conditions. Our aim was to systematically review the management of inflammatory bowel disease. We focused on the issue of early diagnosis and referral to a specialist, the need for personalized therapy and "treat-to-target" concept, and the appropriate timing of referral to a biological therapy center. The levels of competent and responsible care and the structure of a multidisciplinary team were also discussed. For the article, international and Hungarian therapeutic protocols and literature were reviewed. The collaboration of disciplines is essential in the management of chronic diseases. For disease management, it is critical to be up-to-date with changing recommendations, protocols, and to adopt competency levels to achieve a patient's adequate quality of life and reduce disease complications. Orv Hetil. 2021; 162(33): 1311-1317.}, keywords = {Inflammatory bowel disease; Biological therapy; diagnosis; Long-Term Care; BIOLÓGIAI TERÁPIA; gyulladásos bélbetegségek; diagnózis; multidisciplinary team; hosszú távú gondozás; multidiszciplináris csapat}, year = {2021}, eissn = {1788-6120}, pages = {1311-1317}, orcid-numbers = {Sarlós, Patrícia/0000-0002-5086-9455} } @article{MTMT:31709065, title = {Pregnancy outcomes of women whom spouse fathered children after tyrosine kinase inhibitor therapy for chronic myeloid leukemia : A systematic review}, url = {https://m2.mtmt.hu/api/publication/31709065}, author = {Szakács, Zsolt and Hegyi, Péter Jenő and Borbásné Farkas, Kornélia and Hegyi, Péter and Balaskó, Márta and Erős, Adrienn and Szujó, Szabina and Pammer, Judit and Mosdósi, Bernadett and Simon, Mária and Nagy, Arnold and Fűr, Gabriella and Alizadeh, Hussain}, doi = {10.1371/journal.pone.0243045}, journal-iso = {PLOS ONE}, journal = {PLOS ONE}, volume = {15}, unique-id = {31709065}, issn = {1932-6203}, abstract = {The introduction of tyrosine kinase inhibitors (TKIs) has revolutionized the therapy of chronic myeloid leukemia (CML). Although the efficacy of TKIs is beyond dispute, conception-related safety issues are still waiting to be explored, particularly in males. This systematic review aimed to summarize all available evidence on pregnancy outcomes of female spouses of male CML patients who fathered children after TKI treatment for CML.We performed a systematic search in seven electronic databases for studies that reported on male CML patients who did or did not discontinue TKI treatment before conceiving, and the pregnancy outcomes of their female spouse are available. The search centered on the TKI era (from 2001 onward) without any other language or study design restrictions.Out of a total of 38 potentially eligible papers, 27 non-overlapping study cohorts were analyzed. All were descriptive studies (case or case series studies). Altogether, 428 pregnancies from 374 fathers conceived without treatment discontinuation, 400 of which (93.5%) ended up in a live birth. A total of ten offspring with a malformation (2.5%) were reported: six with imatinib (of 313 live births, 1.9%), two with nilotinib (of 26 live births, 7.7%), one with dasatinib (of 43 live births, 2.3%), and none with bosutinib (of 12 live births). Data on CML status were scarcely reported. Only nine pregnancies (from nine males) and no malformation were reported in males who discontinued TKI treatment before conception.Malformations affected, on average 2.5% of live births from fathers who did not discontinue TKI treatment before conception, which is comparable with the rate of malformations in the general population. Large-scale studies with representative samples are awaited to confirm our results.}, year = {2020}, eissn = {1932-6203}, orcid-numbers = {Szakács, Zsolt/0000-0002-7035-941X; Borbásné Farkas, Kornélia/0000-0002-5349-6527; Hegyi, Péter/0000-0003-0399-7259} } @mastersthesis{MTMT:31662183, title = {A gyulladásos bélbetegségben szenvedő serdülők tranzíciós ellátásának hazai és nemzetközi vonatkozásai}, url = {https://m2.mtmt.hu/api/publication/31662183}, author = {Erős, Adrienn}, unique-id = {31662183}, year = {2020} } @article{MTMT:31622967, title = {Effect of joint transition visits on quality of life in adolescents with inflammatory bowel diseases: a protocol for a prospective, randomised, multicentre, controlled trial (TRANS-IBD)}, url = {https://m2.mtmt.hu/api/publication/31622967}, author = {Erős, Adrienn and Dohos, Dóra and Veres, Gábor and Tárnok, András and Vincze, Áron and Tészás, Alexandra and Zádori, Noémi and Gede, Noémi and Hegyi, Péter and Sarlós, Patrícia}, doi = {10.1136/bmjopen-2020-038410}, journal-iso = {BMJ OPEN}, journal = {BMJ OPEN}, volume = {10}, unique-id = {31622967}, issn = {2044-6055}, year = {2020}, eissn = {2044-6055}, orcid-numbers = {Veres, Gábor/0000-0002-0911-1941; Tárnok, András/0000-0001-7019-2755; Vincze, Áron/0000-0003-2217-7686; Hegyi, Péter/0000-0003-0399-7259; Sarlós, Patrícia/0000-0002-5086-9455} } @article{MTMT:31619587, title = {Diet-dependent and diet-independent hemorheological alterations in celiac disease: A case-control study}, url = {https://m2.mtmt.hu/api/publication/31619587}, author = {Szakács, Zsolt and Csiszár, Beáta and Nagy, Mátyás and Borbásné Farkas, Kornélia and Kenyeres, Péter and Erős, Adrienn and Alizadeh, Hussain and Márta, Katalin and Szentesi, Andrea Ildikó and Tőkés-Füzesi, Margit and Berki, Tímea and Vincze, Áron and Tóth, Kálmán and Hegyi, Péter and Bajor, Judit}, doi = {10.14309/ctg.0000000000000256}, journal-iso = {CLIN TRANSLAT GASTROENT}, journal = {CLINICAL AND TRANSLATIONAL GASTROENTEROLOGY}, volume = {11}, unique-id = {31619587}, keywords = {AGGREGATION; PARAMETERS; Erythrocyte Deformability; GUIDELINES; GLUTEN-FREE DIET; plasma viscosity}, year = {2020}, eissn = {2155-384X}, orcid-numbers = {Szakács, Zsolt/0000-0002-7035-941X; Borbásné Farkas, Kornélia/0000-0002-5349-6527; Márta, Katalin/0000-0002-2213-4865; Szentesi, Andrea Ildikó/0000-0003-2097-6927; Berki, Tímea/0000-0002-0134-8127; Vincze, Áron/0000-0003-2217-7686; Hegyi, Péter/0000-0003-0399-7259} } @article{MTMT:31410857, title = {Fatty Liver Disease and Non-Alcoholic Fatty Liver Disease Worsen the Outcome in Acute Pancreatitis : A Systematic Review and Meta-Analysis}, url = {https://m2.mtmt.hu/api/publication/31410857}, author = {Váncsa, Szilárd and Németh, Dávid and Hegyi, Péter and Szakács, Zsolt and Hegyi, Péter Jenő and Pécsi, Dániel and Mikó, Alexandra and Erőss, Bálint Mihály and Erős, Adrienn and Pár, Gabriella}, doi = {10.3390/jcm9092698}, journal-iso = {J CLIN MED}, journal = {JOURNAL OF CLINICAL MEDICINE}, volume = {9}, unique-id = {31410857}, abstract = {The prevalence of fatty liver disease (FLD) and that of non-alcoholic fatty liver disease (NAFLD) share some risk factors known to exacerbate the course of acute pancreatitis (AP). This meta-analysis aimed to investigate whether FLD or NAFLD carry a higher risk of untoward outcomes in AP. In accordance with PRISMA guidelines, we performed a systematic search in seven medical databases for cohort studies that compared the outcomes of AP for the presence of FLD or NAFLD, and we calculated pooled odds ratio (OR) or weighted mean difference (WMD) with 95% confidence interval (CI). We included 13 articles in our meta-analysis. AP patients with FLD were more likely to die (5.09% vs 1.89%, OR = 3.56, CI = 1.75-7.22), develop severe AP (16.33% vs 7.87%, OR = 2.67, CI = 2.01-3.56), necrotizing pancreatitis (34.83% vs 15.75%, OR = 3.08, CI = 2.44-3.90) and had longer in-hospital stay (10.8 vs 9.2 days, WMD = 1.46, OR = 0.54-2.39). Patients with NAFLD were more likely to have severe AP and longer hospital stay. Both FLD and NAFLD proved to be independent risk factors of a more severe disease course (OR = 3.68, CI = 2.16-6.29 and OR = 3.39, CI = 1.52-7.56 for moderate/ severe vs. mild AP, respectively). FLD and NAFLD worsen the outcomes of AP, which suggests that incorporating FLD or NAFLD into prognostic scoring systems of AP outcomes might improve the prediction of severity and contribute to a more individualized patient care.}, keywords = {Prognosis; Acute pancreatitis; Non-Alcoholic Fatty Liver Disease; Hepatology; Fatty liver disease; pancreatology}, year = {2020}, eissn = {2077-0383}, orcid-numbers = {Váncsa, Szilárd/0000-0002-9347-8163; Hegyi, Péter/0000-0003-0399-7259; Szakács, Zsolt/0000-0002-7035-941X; Pécsi, Dániel/0000-0003-0499-6004; Erőss, Bálint Mihály/0000-0003-3658-8427} } @article{MTMT:31376050, title = {A cross-sectional survey on the transitional care of adolescents with inflammatory bowel disease in Hungary}, url = {https://m2.mtmt.hu/api/publication/31376050}, author = {Erős, Adrienn and Veres, Gábor and Tárnok, András and Dohos, Dóra and Otto, Caroline and Szakács, Zsolt and Hegyi, Péter and Vincze, Áron and Sarlós, Patrícia}, doi = {10.1016/j.pedn.2020.06.002}, journal-iso = {J PEDIATR NURS}, journal = {JOURNAL OF PEDIATRIC NURSING: NURSING CARE OF CHILDREN AND FAMILIES}, volume = {55}, unique-id = {31376050}, issn = {0882-5963}, abstract = {Since little is known about transitional care practices of adolescents with inflammatory bowel diseases (IBD) in Central-Eastern Europe, we aimed to investigate the currently applied transition practices in Hungary.A nationwide, multicentre survey was conducted with the invitation of 41 pediatric and adult IBD centres in February 2019.We developed a 34-item questionnaire, which included single- and multiple-choice questions related to the current clinical practice of IBD transition.The overall response rate was 31.7% (13/41); answers came predominantly from tertiary centres. Only 15.4% of the respondent centres followed international IBD guidelines. The majority of the IBD centres provided transition support; however, responses revealed a marked heterogeneity of these services. Joint visits were held only in 54% of the clinics. Gastroenterologists and next of kin are not provided education regarding transition across most centres (85 and 92%). Although adolescents received age-specific education, transition readiness was not measured. More IBD nurses and dietitians were employed in adult centres than in pediatric ones.The current survey revealed critical gaps in the Hungarian IBD transition practices. As the beneficial effects of structured IBD transition programmes are recognized in Hungary, there is a growing need for the introduction of new, more effective transition practices.Our results can serve as a basis for planning more effective transition strategies.}, keywords = {ulcerative colitis; Crohn's disease; inflammatory bowel diseases; transitional care; Structured transition}, year = {2020}, eissn = {1532-8449}, pages = {e279-e285}, orcid-numbers = {Veres, Gábor/0000-0002-0911-1941; Tárnok, András/0000-0001-7019-2755; Szakács, Zsolt/0000-0002-7035-941X; Hegyi, Péter/0000-0003-0399-7259; Vincze, Áron/0000-0003-2217-7686; Sarlós, Patrícia/0000-0002-5086-9455} } @article{MTMT:31315923, title = {Efficacy and safety of stenting and additional oncological treatment versus stenting alone in unresectable esophageal cancer: a meta-analysis and systematic review}, url = {https://m2.mtmt.hu/api/publication/31315923}, author = {Tinusz, Benedek and Soós, Alexandra and Hegyi, Péter and Sarlós, Patrícia and Szapáry, László Botond and Erős, Adrienn and Feczák, Donáta and Szakács, Zsolt and Márta, Katalin and Venglovecz, Viktória and Erőss, Bálint Mihály}, doi = {10.1016/j.radonc.2020.05.015}, journal-iso = {RADIOTHER ONCOL}, journal = {RADIOTHERAPY AND ONCOLOGY}, volume = {147}, unique-id = {31315923}, issn = {0167-8140}, year = {2020}, eissn = {1879-0887}, pages = {169-177}, orcid-numbers = {Soós, Alexandra/0000-0001-9305-5251; Hegyi, Péter/0000-0003-0399-7259; Sarlós, Patrícia/0000-0002-5086-9455; Szakács, Zsolt/0000-0002-7035-941X; Márta, Katalin/0000-0002-2213-4865; Venglovecz, Viktória/0000-0002-2316-7247; Erőss, Bálint Mihály/0000-0003-3658-8427} }