TY - THES AU - Józó, Muriel TI - Functional biopolymers for medical applications PB - Budapesti Műszaki és Gazdaságtudományi Egyetem PY - 2022 SP - 146 UR - https://m2.mtmt.hu/api/publication/33643160 ID - 33643160 LA - English DB - MTMT ER - TY - JOUR AU - Józó, Muriel AU - Várdai, Róbert AU - Bartos, András AU - Móczó, János AU - Pukánszky, Béla TI - Preparation of Biocomposites with Natural Reinforcements: The Effect of Native Starch and Sugarcane Bagasse Fibers JF - MOLECULES J2 - MOLECULES VL - 27 PY - 2022 IS - 19 PG - 15 SN - 1420-3049 DO - 10.3390/molecules27196423 UR - https://m2.mtmt.hu/api/publication/33189814 ID - 33189814 N1 - Laboratory of Plastics and Rubber Technology, Department of Physical Chemistry and Materials Science, Budapest University of Technology and Economics, Műegyetem rkp. 3, Budapest, H-1111, Hungary Institute of Materials and Environmental Chemistry, Research Centre for Natural Sciences, P.O. Box 286, Budapest, H-1519, Hungary Export Date: 25 October 2022 CODEN: MOLEF Correspondence Address: Várdai, R.; Laboratory of Plastics and Rubber Technology, Műegyetem rkp. 3, Hungary; email: vardai.robert@vbk.bme.hu AB - Biocomposites were prepared from poly(lactic acid) and two natural reinforcements, a native starch and sugarcane bagasse fibers. The strength of interfacial adhesion was estimated by model calculations, and local deformation processes were followed by acoustic emission testing. The results showed that the two additives influence properties differently. The strength of interfacial adhesion and thus the extent of reinforcement are similar because of similarities in chemical structure, the large number of OH groups in both reinforcements. Relatively strong interfacial adhesion develops between the components, which renders coupling inefficient. Dissimilar particle characteristics influence local deformation processes considerably. The smaller particle size of starch results in larger debonding stress and thus larger composite strength. The fracture of the bagasse fibers leads to larger energy consumption and to increased impact resistance. Although the environmental benefit of the prepared biocomposites is similar, the overall performance of the bagasse fiber reinforced PLA composites is better than that offered by the PLA/starch composites. LA - English DB - MTMT ER - TY - JOUR AU - Józó, Muriel AU - Simon, Nóra AU - Yi, Lan AU - Móczó, János AU - Pukánszky, Béla TI - Improved Release of a Drug with Poor Water Solubility by Using Electrospun Water-Soluble Polymers as Carriers JF - PHARMACEUTICS J2 - PHARMACEUTICS VL - 14 PY - 2022 IS - 1 PG - 17 SN - 1999-4923 DO - 10.3390/pharmaceutics14010034 UR - https://m2.mtmt.hu/api/publication/32588966 ID - 32588966 N1 - Laboratory of Plastics and Rubber Technology, Department of Physical Chemistry and Materials Science, Budapest University of Technology and Economics, Budapest, H-1521, Hungary Institute of Materials and Environmental Chemistry, Research Centre for Natural Sciences, ELKH Eötvös Loránd Research Network, Budapest, H-1519, Hungary Export Date: 29 April 2022 Correspondence Address: Móczó, J.; Laboratory of Plastics and Rubber Technology, Hungary; email: jmoczo@edu.bme.hu AB - n an attempt to improve the solubility of valsartan, a BCS II drug, fibers containing the drug were prepared from three water-soluble polymers, hydroxypropyl-methyl-cellulose (HPMC), polyvinyl-pyrrolidone (PVP), and polyvinyl-alcohol (PVA). Fiber spinning technology was optimized for each polymer separately. The polymers contained 20 wt% of the active component. The drug was homogenously distributed within the fibers in the amorphous form. The presence of the drug interfered with the spinning process only slightly, the diameters of the fibers were in the same range as without the drug for the HPMC and the PVA fibers, while it doubled in PVP. The incorporation of the drug into the fibers increased its solubility in all cases compared to that of the neat drug. The solubility of the drug itself depends very much on pH and this sensitivity remained the same in the HPMC and PVP fibers; the release of the drug is dominated by the dissolution behavior of valsartan itself. On the other hand, solubility and the rate of release were practically independent of pH in the PVA fibers. The different behavior is explained by the rate of the dissolution of the respective polymer, which is larger for HPMC and PVP, and smaller for PVA than the dissolution rate of the drug. The larger extent of release compared to neat valsartan can be explained by the lack of crystallinity of the drug, its better dispersion, and the larger surface area of the fibers. Considering all facts, the preparation of electrospun devices from valsartan and water-soluble polymers is beneficial, and the use of PVA is more advantageous than that of the other two polymers. LA - English DB - MTMT ER - TY - JOUR AU - Józó, Muriel AU - Várdai, Róbert AU - Hegyesi, Nóra AU - Móczó, János AU - Pukánszky, Béla TI - Poly-ε-Caprolactone/Halloysite Nanotube Composites for Resorbable Scaffolds: Effect of Processing Technology on Homogeneity and Electrospinning JF - POLYMERS J2 - POLYMERS-BASEL VL - 13 PY - 2021 IS - 21 PG - 17 SN - 2073-4360 DO - 10.3390/polym13213772 UR - https://m2.mtmt.hu/api/publication/32540683 ID - 32540683 N1 - Laboratory of Plastics and Rubber Technology, Department of Physical Chemistry and Materials Science, Budapest University of Technology and Economics, P.O. Box 91, Budapest, H-1521, Hungary Institute of Materials and Environmental Chemistry, Research Centre for Natural Sciences, ELKH Eötvös Loránd Research Network, P.O. Box 286, Budapest, H-1519, Hungary Export Date: 18 February 2022 Correspondence Address: Pukánszky, B.; Laboratory of Plastics and Rubber Technology, P.O. Box 91, Hungary; email: pukanszky.bela@vbk.bme.hu Funding details: Budapesti Műszaki és Gazdaságtudományi Egyetem, BME Funding details: Emberi Eroforrások Minisztériuma, EMMI Funding text 1: Funding: The research was partly funded by the BME Nanotechnology FIKP Grant of EMMI (BME FIKP-NAT). LA - English DB - MTMT ER - TY - JOUR AU - Koplányi, Gábor AU - Bell, Evelin AU - Molnár, Zsófia Klára AU - Tóth, Gergő Dániel AU - Józó, Muriel AU - Szilágyi, András Ferenc AU - Ender, Ferenc AU - Pukánszky, Béla AU - Vértessy, Beáta (Grolmuszné) AU - Poppe, László AU - Balogh Weiser, Diána TI - Entrapment of Phenylalanine Ammonia-Lyase in Nanofibrous Polylactic Acid Matrices by Emulsion Electrospinning JF - CATALYSTS J2 - CATALYSTS VL - 11 PY - 2021 IS - 10 PG - 14 SN - 2073-4344 DO - 10.3390/catal11101149 UR - https://m2.mtmt.hu/api/publication/32242806 ID - 32242806 N1 - Export Date: 26 October 2021 LA - English DB - MTMT ER - TY - JOUR AU - Józó, Muriel AU - Cui, L. AU - Bordácsné Bocz, Katalin AU - Pukánszky, Béla TI - Processing induced segregation in PLA/TPS blends: Factors and consequences JF - EXPRESS POLYMER LETTERS J2 - EXPRESS POLYM LETT VL - 14 PY - 2020 IS - 8 SP - 768 EP - 779 PG - 12 SN - 1788-618X DO - 10.3144/expresspolymlett.2020.63 UR - https://m2.mtmt.hu/api/publication/31424741 ID - 31424741 N1 - Funding Agency and Grant Number: National Scientific Research Fund of Hungary (OTKA)Orszagos Tudomanyos Kutatasi Alapprogramok (OTKA) [K 120039, FK 129270] Funding text: The significant help of Peter Muller, Jozsef Bere, and Erika Fekete Bodine in sample preparation and measurements is highly appreciated. The authors acknowledge the financial support of the National Scientific Research Fund of Hungary (OTKA Grant No. K 120039 and FK 129270) for this project on the modification of polymeric materials. Laboratory of Plastics and Rubber Technology, Department of Physical Chemistry and Materials Science, Budapest University of Technology and Economics, P.O. Box 91, Budapest, H-1521, Hungary Institute of Materials and Environmental Chemistry, Chemical Research Center, P.O. Box 286, Budapest, H-1519, Hungary Department of Organic Chemistry and Technology, Budapest University of Technology and Economics, P.O. Box 91, Budapest, H-1521, Hungary Export Date: 4 February 2021 Correspondence Address: Pukánszky, B.; Laboratory of Plastics and Rubber Technology, P.O. Box 91, Hungary; email: bpukanszky@mail.bme.hu Funding details: Hungarian Scientific Research Fund, OTKA Funding text 1: The significant help of Péter Müller, József Bere, and Erika Fekete Bódiné in sample preparation and measurements is highly appreciated. The authors acknowledge the financial support of the National Scientific Research Fund of Hungary (OTKA Grant No. K 120039 and FK 129270) for this project on the modification of polymeric materials. AB - Poly(lactic acid) (PLA) and thermoplastic starch (TPS) blends with two different glycerol contents were prepared by injection molding. Mechanical properties were characterized by tensile and impact testing, structure by scanning electron microscopy (SEM), Fourier transform infrared (FTIR) as well as Raman spectroscopy, and water absorption was determined as a function of time. Compression-molded specimens were used as reference. The properties of the blends cover a wide range, stiffness changes from 3.3 to around 1.0 GPa, while strength from 54 to 22 MPa as TPS content increases from 0 to 50 wt%. Heterogeneous structure forms in the blends because of the weak interaction of the components. Processing conditions do not change bulk properties. Weak interactions and the large difference in the viscosity of the components lead to the formation of a skin on the surface of the specimens. The skin consists mainly of PLA, while the core contains a larger amount of TPS. The thickness of the skin depends on processing technology and conditions; it is about 18 mu m for the injectionmolded, while 4.5 mu m for the compression-molded parts at 50 wt% TPS content. The development of the skin layer can be advantageous in some applications because it slows down water absorption considerably. LA - English DB - MTMT ER - TY - JOUR AU - Budai-Szűcs, Mária AU - Léber, Attila AU - Cui, Lu AU - Józó, Muriel AU - Vályi, Péter AU - Burián, Katalin AU - Kirschweng, Balázs László AU - Csányi, Erzsébet AU - Pukánszky, Béla TI - Electrospun PLA Fibers Containing Metronidazole for Periodontal Disease JF - DRUG DESIGN DEVELOPMENT AND THERAPY J2 - DRUG DES DEV THER VL - 14 PY - 2020 SP - 233 EP - 242 PG - 10 SN - 1177-8881 DO - 10.2147/DDDT.S231748 UR - https://m2.mtmt.hu/api/publication/31128396 ID - 31128396 LA - English DB - MTMT ER - TY - CONF AU - Józó, Muriel TI - Injection Molding Process with Innovative Material to Replace Petroleum Based Plastic T2 - 56th Annual Value Summit: Celebrating 70 Years of Value PB - SAVE International PY - 2017 UR - https://m2.mtmt.hu/api/publication/3399231 ID - 3399231 N1 - Scopus:hiba:85041903933 2022-10-12 14:38 típus nem egyezik, év nem egyezik LA - English DB - MTMT ER -