@mastersthesis{MTMT:33643160, title = {Functional biopolymers for medical applications}, url = {https://m2.mtmt.hu/api/publication/33643160}, author = {Józó, Muriel}, publisher = {Budapest University of Technology and Economics}, unique-id = {33643160}, year = {2022} } @article{MTMT:33189814, title = {Preparation of Biocomposites with Natural Reinforcements: The Effect of Native Starch and Sugarcane Bagasse Fibers}, url = {https://m2.mtmt.hu/api/publication/33189814}, author = {Józó, Muriel and Várdai, Róbert and Bartos, András and Móczó, János and Pukánszky, Béla}, doi = {10.3390/molecules27196423}, journal-iso = {MOLECULES}, journal = {MOLECULES}, volume = {27}, unique-id = {33189814}, issn = {1420-3049}, abstract = {Biocomposites were prepared from poly(lactic acid) and two natural reinforcements, a native starch and sugarcane bagasse fibers. The strength of interfacial adhesion was estimated by model calculations, and local deformation processes were followed by acoustic emission testing. The results showed that the two additives influence properties differently. The strength of interfacial adhesion and thus the extent of reinforcement are similar because of similarities in chemical structure, the large number of OH groups in both reinforcements. Relatively strong interfacial adhesion develops between the components, which renders coupling inefficient. Dissimilar particle characteristics influence local deformation processes considerably. The smaller particle size of starch results in larger debonding stress and thus larger composite strength. The fracture of the bagasse fibers leads to larger energy consumption and to increased impact resistance. Although the environmental benefit of the prepared biocomposites is similar, the overall performance of the bagasse fiber reinforced PLA composites is better than that offered by the PLA/starch composites.}, year = {2022}, eissn = {1420-3049} } @article{MTMT:32588966, title = {Improved Release of a Drug with Poor Water Solubility by Using Electrospun Water-Soluble Polymers as Carriers}, url = {https://m2.mtmt.hu/api/publication/32588966}, author = {Józó, Muriel and Simon, Nóra and Yi, Lan and Móczó, János and Pukánszky, Béla}, doi = {10.3390/pharmaceutics14010034}, journal-iso = {PHARMACEUTICS}, journal = {PHARMACEUTICS}, volume = {14}, unique-id = {32588966}, issn = {1999-4923}, abstract = {n an attempt to improve the solubility of valsartan, a BCS II drug, fibers containing the drug were prepared from three water-soluble polymers, hydroxypropyl-methyl-cellulose (HPMC), polyvinyl-pyrrolidone (PVP), and polyvinyl-alcohol (PVA). Fiber spinning technology was optimized for each polymer separately. The polymers contained 20 wt% of the active component. The drug was homogenously distributed within the fibers in the amorphous form. The presence of the drug interfered with the spinning process only slightly, the diameters of the fibers were in the same range as without the drug for the HPMC and the PVA fibers, while it doubled in PVP. The incorporation of the drug into the fibers increased its solubility in all cases compared to that of the neat drug. The solubility of the drug itself depends very much on pH and this sensitivity remained the same in the HPMC and PVP fibers; the release of the drug is dominated by the dissolution behavior of valsartan itself. On the other hand, solubility and the rate of release were practically independent of pH in the PVA fibers. The different behavior is explained by the rate of the dissolution of the respective polymer, which is larger for HPMC and PVP, and smaller for PVA than the dissolution rate of the drug. The larger extent of release compared to neat valsartan can be explained by the lack of crystallinity of the drug, its better dispersion, and the larger surface area of the fibers. Considering all facts, the preparation of electrospun devices from valsartan and water-soluble polymers is beneficial, and the use of PVA is more advantageous than that of the other two polymers.}, year = {2022}, eissn = {1999-4923}, orcid-numbers = {Yi, Lan/0000-0002-0551-3804} } @article{MTMT:32540683, title = {Poly-ε-Caprolactone/Halloysite Nanotube Composites for Resorbable Scaffolds: Effect of Processing Technology on Homogeneity and Electrospinning}, url = {https://m2.mtmt.hu/api/publication/32540683}, author = {Józó, Muriel and Várdai, Róbert and Hegyesi, Nóra and Móczó, János and Pukánszky, Béla}, doi = {10.3390/polym13213772}, journal-iso = {POLYMERS-BASEL}, journal = {POLYMERS}, volume = {13}, unique-id = {32540683}, year = {2021}, eissn = {2073-4360} } @article{MTMT:32242806, title = {Entrapment of Phenylalanine Ammonia-Lyase in Nanofibrous Polylactic Acid Matrices by Emulsion Electrospinning}, url = {https://m2.mtmt.hu/api/publication/32242806}, author = {Koplányi, Gábor and Bell, Evelin and Molnár, Zsófia Klára and Tóth, Gergő Dániel and Józó, Muriel and Szilágyi, András Ferenc and Ender, Ferenc and Pukánszky, Béla and Vértessy, Beáta (Grolmuszné) and Poppe, László and Balogh Weiser, Diána}, doi = {10.3390/catal11101149}, journal-iso = {CATALYSTS}, journal = {CATALYSTS}, volume = {11}, unique-id = {32242806}, year = {2021}, eissn = {2073-4344}, orcid-numbers = {Koplányi, Gábor/0000-0002-3791-1057; Szilágyi, András Ferenc/0000-0001-6898-1755; Ender, Ferenc/0000-0003-3800-5707; Poppe, László/0000-0002-8358-1378; Balogh Weiser, Diána/0000-0002-9957-1203} } @article{MTMT:31424741, title = {Processing induced segregation in PLA/TPS blends: Factors and consequences}, url = {https://m2.mtmt.hu/api/publication/31424741}, author = {Józó, Muriel and Cui, L. and Bordácsné Bocz, Katalin and Pukánszky, Béla}, doi = {10.3144/expresspolymlett.2020.63}, journal-iso = {EXPRESS POLYM LETT}, journal = {EXPRESS POLYMER LETTERS}, volume = {14}, unique-id = {31424741}, issn = {1788-618X}, abstract = {Poly(lactic acid) (PLA) and thermoplastic starch (TPS) blends with two different glycerol contents were prepared by injection molding. Mechanical properties were characterized by tensile and impact testing, structure by scanning electron microscopy (SEM), Fourier transform infrared (FTIR) as well as Raman spectroscopy, and water absorption was determined as a function of time. Compression-molded specimens were used as reference. The properties of the blends cover a wide range, stiffness changes from 3.3 to around 1.0 GPa, while strength from 54 to 22 MPa as TPS content increases from 0 to 50 wt%. Heterogeneous structure forms in the blends because of the weak interaction of the components. Processing conditions do not change bulk properties. Weak interactions and the large difference in the viscosity of the components lead to the formation of a skin on the surface of the specimens. The skin consists mainly of PLA, while the core contains a larger amount of TPS. The thickness of the skin depends on processing technology and conditions; it is about 18 mu m for the injectionmolded, while 4.5 mu m for the compression-molded parts at 50 wt% TPS content. The development of the skin layer can be advantageous in some applications because it slows down water absorption considerably.}, keywords = {COMPOSITES; MORPHOLOGY; mechanical properties; MECHANICAL-PROPERTIES; thermoplastic starch; water absorption; Biopolymers; Interactions; PLA; interfacial adhesion; skin and core structure; FUNCTIONALIZING POLYMER SURFACES; COPOLYMER ADDITIVES; INDUCED MIGRATION}, year = {2020}, eissn = {1788-618X}, pages = {768-779} } @article{MTMT:31128396, title = {Electrospun PLA Fibers Containing Metronidazole for Periodontal Disease}, url = {https://m2.mtmt.hu/api/publication/31128396}, author = {Budai-Szűcs, Mária and Léber, Attila and Cui, Lu and Józó, Muriel and Vályi, Péter and Burián, Katalin and Kirschweng, Balázs László and Csányi, Erzsébet and Pukánszky, Béla}, doi = {10.2147/DDDT.S231748}, journal-iso = {DRUG DES DEV THER}, journal = {DRUG DESIGN DEVELOPMENT AND THERAPY}, volume = {14}, unique-id = {31128396}, issn = {1177-8881}, year = {2020}, pages = {233-242}, orcid-numbers = {Budai-Szűcs, Mária/0000-0001-5187-5702; Cui, Lu/0000-0001-8722-5314; Józó, Muriel/0000-0001-9213-8493; Vályi, Péter/0000-0002-9594-2038; Burián, Katalin/0000-0003-1300-2374; Kirschweng, Balázs László/0000-0002-6090-2263; Csányi, Erzsébet/0000-0002-3010-1959; Pukánszky, Béla/0000-0002-3920-5068} } @CONFERENCE{MTMT:3399231, title = {Injection Molding Process with Innovative Material to Replace Petroleum Based Plastic}, url = {https://m2.mtmt.hu/api/publication/3399231}, author = {Józó, Muriel}, booktitle = {56th Annual Value Summit: Celebrating 70 Years of Value}, unique-id = {3399231}, year = {2017} }