@article{MTMT:35777618,
	title = {Anticancer organometallic half-sandwich complexes of estrone-derived (N,N) donor ligands with enhanced aqueous solubility},
	url = {https://m2.mtmt.hu/api/publication/35777618},
	author = {Pivarcsik, Tamás and Kovács, Ferenc and Spengler, Gabriella and Nové, Márta and Keppler, Bernhard K. and Kandioller, Wolfgang and Nagyné Frank, Éva and Enyedy, Éva Anna},
	doi = {10.1016/j.jinorgbio.2025.112858},
	journal-iso = {J INORG BIOCHEM},
	journal = {JOURNAL OF INORGANIC BIOCHEMISTRY},
	volume = {267},
	unique-id = {35777618},
	issn = {0162-0134},
	year = {2025},
	eissn = {1873-3344},
	orcid-numbers = {Spengler, Gabriella/0000-0001-8085-0950; Nagyné Frank, Éva/0000-0002-1332-0551; Enyedy, Éva Anna/0000-0002-8058-8128}
}

@CONFERENCE{MTMT:35518284,
	title = {Drug repurposing strategy in bacterial infections: phenothiazine antipsychotics as efflux pump inhibitors},
	url = {https://m2.mtmt.hu/api/publication/35518284},
	author = {Nové, Márta and Rácz, Bálint and Kincses, Annamária and Spengler, Gabriella},
	booktitle = {Magyar Mikrobiológiai Társaság 2024. évi Nagygyűlése/ Hungarian Society for Microbiology General Meeting 2024. - Absztraktok/ Abstracts},
	unique-id = {35518284},
	year = {2024},
	pages = {26-27},
	orcid-numbers = {Rácz, Bálint/0000-0003-0088-3408; Kincses, Annamária/0000-0002-1591-1419; Spengler, Gabriella/0000-0001-8085-0950}
}

@article{MTMT:35480474,
	title = {Structural and Solution Speciation Studies on fac -Tricarbonylrhenium(I) Complexes of 2,2′-Bipyridine Analogues},
	url = {https://m2.mtmt.hu/api/publication/35480474},
	author = {Pivarcsik, Tamás and Kljun, Jakob and Clemente Rodriguez, Sergio and Cortéz Alcaraz, David and Rapuš, Uroš and Nové, Márta and F. Várkonyi, Egon and Nyári, József and Bogdanov, Anita and Spengler, Gabriella and Turel, Iztok and Enyedy, Éva Anna},
	doi = {10.1021/acsomega.4c07117},
	journal-iso = {ACS OMEGA},
	journal = {ACS OMEGA},
	volume = {9},
	unique-id = {35480474},
	issn = {2470-1343},
	year = {2024},
	eissn = {2470-1343},
	pages = {44601-44615},
	orcid-numbers = {Bogdanov, Anita/0000-0003-3067-8835; Spengler, Gabriella/0000-0001-8085-0950; Turel, Iztok/0000-0001-6776-4062; Enyedy, Éva Anna/0000-0002-8058-8128}
}

@article{MTMT:35078258,
	title = {Preparation of dearomatized p‐coumaric acid derivatives as DNA damage response inhibitors with potent in vitro antitumor effect},
	url = {https://m2.mtmt.hu/api/publication/35078258},
	author = {Fási, Laura and Gonda, Tímea and Crul-Tóth, Noémi and Vass, Máté and Gyovai, András and Nagy, Viktória and Ocsovszki, Imre and Zupkó, István and Kúsz, Norbert and Nové, Márta and Spengler, Gabriella and Berkecz, Róbert and Wang, Hui-Chun and Chang, Fang-Rong and Hunyadi, Attila},
	doi = {10.1002/cmdc.202300675},
	journal-iso = {CHEMMEDCHEM},
	journal = {CHEMMEDCHEM},
	volume = {19},
	unique-id = {35078258},
	issn = {1860-7179},
	abstract = {Our research group previously identified graviquinone (1) as a promising antitumor metabolite that is formed in situ when the antioxidant methyl caffeate scavenges free radicals. Furthermore, it exerted a DNA damaging effect on cancer cells and a DNA protective effect on normal keratinocytes. To expand and explore chemical space around qraviquinone, in the current work we synthesized 9 new alkyl‐substituted derivatives and tested their in vitro antitumor potential. All new compounds bypassed ABCB1‐mediated multidrug resistance and showed highly different cell line specificity compared with 1. All compounds were more potent in MDA‐MB‐231 than on MCF‐7 cells. The n‐butyl‐substituted derivatives 2 and 8 modulated the cell cycle and inhibited the ATR‐mediated phosphorylation of checkpoint kinase‐1 in MCF‐7 cells. As a significant expansion of our previous findings, our results highlight the potential antitumor value of alkyl‐substituted graviquinone derivatives.},
	year = {2024},
	eissn = {1860-7187},
	orcid-numbers = {Gyovai, András/0000-0003-2316-2160; Ocsovszki, Imre/0000-0003-1290-996X; Zupkó, István/0000-0003-3243-5300; Kúsz, Norbert/0000-0002-9973-6442; Spengler, Gabriella/0000-0001-8085-0950; Berkecz, Róbert/0000-0002-9076-2177; Hunyadi, Attila/0000-0003-0074-3472}
}

@article{MTMT:33150816,
	title = {Seleno-vs. thioether triazine derivatives in search for new anticancer agents overcoming multidrug resistance in lymphoma},
	url = {https://m2.mtmt.hu/api/publication/33150816},
	author = {Ali, Wesam and Garbo, Sabrina and Kincses, Annamária and Nové, Márta and Spengler, Gabriella and Di Bello, Elisabetta and Honkisz-Orzechowska, Ewelina and Karcz, Tadeusz and Szymańska, Ewa and Żesławska, Ewa and Starek, Małgorzata and Dąbrowska, Monika and Nitek, Wojciech and Kucwaj-Brysz, Katarzyna and Pyka, Patryk and Fioravanti, Rossella and Jacob, Claus and Battistelli, Cecilia and Zwergel, Clemens and Handzlik, Jadwiga},
	doi = {10.1016/j.ejmech.2022.114761},
	journal-iso = {EUR J MED CHEM},
	journal = {EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY},
	volume = {243},
	unique-id = {33150816},
	issn = {0223-5234},
	year = {2022},
	eissn = {1768-3254},
	orcid-numbers = {Kincses, Annamária/0000-0002-1591-1419; Spengler, Gabriella/0000-0001-8085-0950; Zwergel, Clemens/0000-0002-3097-0003}
}

@mastersthesis{MTMT:32855418,
	title = {Efflux pump inhibitors and potential adjuvants to reverse multidrug resistance in bacteria and tumor cells [Multidrog rezisztencia visszafordítása efflux pumpa gátló vegyületekkel és lehetséges adjuvánsokkal baktériumokban és tumorsejtekben]},
	url = {https://m2.mtmt.hu/api/publication/32855418},
	author = {Nové, Márta},
	doi = {10.14232/phd.11230},
	publisher = {SZTE},
	unique-id = {32855418},
	year = {2022}
}

@article{MTMT:32770194,
	title = {Diversity-Oriented Synthesis Catalyzed by Diethylaminosulfur-Trifluoride—Preparation of New Antitumor Ecdysteroid Derivatives},
	url = {https://m2.mtmt.hu/api/publication/32770194},
	author = {Vágvölgyi, Máté and Kocsis, Endre and Nové, Márta and Szemerédi, Nikoletta and Spengler, Gabriella and Kele, Zoltán and Berkecz, Róbert and Gáti, Tamás and Tóth, Gábor and Hunyadi, Attila},
	doi = {10.3390/ijms23073447},
	journal-iso = {INT J MOL SCI},
	journal = {INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES},
	volume = {23},
	unique-id = {32770194},
	issn = {1661-6596},
	abstract = {Fluorine represents a privileged building block in pharmaceutical chemistry. Diethylaminosulfur-trifluoride (DAST) is a reagent commonly used for replacement of alcoholic hydroxyl groups with fluorine and is also known to catalyze water elimination and cyclic Beckmann-rearrangement type reactions. In this work we aimed to use DAST for diversity-oriented semisynthetic transformation of natural products bearing multiple hydroxyl groups to prepare new bioactive compounds. Four ecdysteroids, including a new constituent of Cyanotis arachnoidea, were selected as starting materials for DAST-catalyzed transformations. The newly prepared compounds represented combinations of various structural changes DAST was known to catalyze, and a unique cyclopropane ring closure that was found for the first time. Several compounds demonstrated in vitro antitumor properties. A new 17-N-acetylecdysteroid (13) exerted potent antiproliferative activity and no cytotoxicity on drug susceptible and multi-drug resistant mouse T-cell lymphoma cells. Further, compound 13 acted in significant synergism with doxorubicin without detectable direct ABCB1 inhibition. Our results demonstrate that DAST is a versatile tool for diversity-oriented synthesis to expand chemical space towards new bioactive compounds.},
	keywords = {NMR; FLUORINATION; structure elucidation; natural product; ecdysteroid; Anticancer},
	year = {2022},
	eissn = {1422-0067},
	orcid-numbers = {Vágvölgyi, Máté/0000-0002-2233-9422; Spengler, Gabriella/0000-0001-8085-0950; Kele, Zoltán/0000-0002-4401-0302; Berkecz, Róbert/0000-0002-9076-2177; Hunyadi, Attila/0000-0003-0074-3472}
}

@article{MTMT:32201163,
	title = {Cyano- and Ketone-Containing Selenoesters as Multi-Target Compounds against Resistant Cancers},
	url = {https://m2.mtmt.hu/api/publication/32201163},
	author = {Szemerédi, Nikoletta and Dobiasová, Simona and Salardón-Jiménez, Noemi and Kincses, Annamária and Nové, Márta and Habibullah, Giyaullah and Sevilla-Hernández, Clotilde and Benito-Lama, Miguel and Alonso-Martínez, Francisco-Javier and Viktorová, Jitka and Spengler, Gabriella and Domínguez-Álvarez, Enrique},
	doi = {10.3390/cancers13184563},
	journal-iso = {CANCERS},
	journal = {CANCERS},
	volume = {13},
	unique-id = {32201163},
	year = {2021},
	eissn = {2072-6694},
	orcid-numbers = {Salardón-Jiménez, Noemi/0000-0002-2215-804X; Kincses, Annamária/0000-0002-1591-1419; Habibullah, Giyaullah/0000-0001-9455-655X; Sevilla-Hernández, Clotilde/0000-0002-0745-5281; Viktorová, Jitka/0000-0003-0857-153X; Spengler, Gabriella/0000-0001-8085-0950; Domínguez-Álvarez, Enrique/0000-0003-2655-1575}
}

@article{MTMT:31696470,
	title = {In vitro adjuvant antitumor activity of various classes of semi-synthetic poststerone derivatives},
	url = {https://m2.mtmt.hu/api/publication/31696470},
	author = {Savchenko, Rimma G. and Nové, Márta and Spengler, Gabriella and Hunyadi, Attila and Parfenova, Lyudmila V.},
	doi = {10.1016/j.bioorg.2020.104485},
	journal-iso = {BIOORG CHEM},
	journal = {BIOORGANIC CHEMISTRY},
	volume = {106},
	unique-id = {31696470},
	issn = {0045-2068},
	year = {2021},
	eissn = {1090-2120},
	orcid-numbers = {Spengler, Gabriella/0000-0001-8085-0950; Hunyadi, Attila/0000-0003-0074-3472}
}

@article{MTMT:31656647,
	title = {Alkylated monoterpene indole alkaloid derivatives as potent P-glycoprotein inhibitors in resistant cancer cells},
	url = {https://m2.mtmt.hu/api/publication/31656647},
	author = {Cardoso, David S.P. and Kincses, Annamária and Nové, Márta and Spengler, Gabriella and Mulhovo, Silva and Aires-de-Sousa, João and dos Santos, Daniel J.V. A. and Ferreira, Maria-José U.},
	doi = {10.1016/j.ejmech.2020.112985},
	journal-iso = {EUR J MED CHEM},
	journal = {EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY},
	volume = {210},
	unique-id = {31656647},
	issn = {0223-5234},
	year = {2021},
	eissn = {1768-3254},
	orcid-numbers = {Cardoso, David S.P./0000-0002-8270-4276; Kincses, Annamária/0000-0002-1591-1419; Spengler, Gabriella/0000-0001-8085-0950}
}