TY - CONF AU - Igaz, Nóra AU - Szőke, Krisztina AU - Bocz, Csenge AU - Kovács, Dávid AU - Rónavári, Andrea AU - Szabó, Emilia Rita AU - Polanek, Róbert AU - Buhala, Andrea AU - Vizler, Csaba AU - Tiszlavicz, László AU - Rázga, Zsolt AU - Hideghéty, Katalin AU - Kónya, Zoltán AU - Csontné Kiricsi, Mónika TI - Radiosensitizing effect of metal nanoparticles in combination with histone deacetylase inhibitors T2 - FAMÉ 2023 PY - 2023 SP - 75 EP - 76 PG - 2 UR - https://m2.mtmt.hu/api/publication/34154565 ID - 34154565 LA - English DB - MTMT ER - TY - JOUR AU - Beyreuther, E. AU - Pawelke, J. AU - Brand, M. AU - Hans, S. AU - Hideghéty, Katalin AU - Jansen, J. AU - Karsch, L. AU - Lessmann, E. AU - Löck, S. AU - Schürer, M. AU - Seco, J. AU - Szabó, Emilia Rita AU - Schramm, U. TI - OC-0094 Beam pulse structure affects the magnitude of Flash effect in zebrafish embryo JF - RADIOTHERAPY AND ONCOLOGY J2 - RADIOTHER ONCOL VL - 170 PY - 2022 SP - S69 EP - S70 PG - 2 SN - 0167-8140 DO - 10.1016/S0167-8140(22)02470-7 UR - https://m2.mtmt.hu/api/publication/34074689 ID - 34074689 LA - English DB - MTMT ER - TY - JOUR AU - Varmazyar, Parvin AU - Singh, Prashant K. AU - Elekes, Zoltán AU - Halász, Zoltán AU - Nagy, Bence AU - Son, Joon-Gon AU - Csontos, János AU - Mohácsi, Árpád AU - Nelissen, Kwinten AU - Somoskői, Tamás AU - Szabó, Emilia Rita AU - Tóth, Szabolcs AU - Ter-Avetisyan, Sargis AU - Osvay, Károly TI - Calibration of micro-channel plate detector in a Thomson spectrometer for protons and carbon ions with energies below 1 MeV JF - REVIEW OF SCIENTIFIC INSTRUMENTS J2 - REV SCI INSTRUM VL - 93 PY - 2022 IS - 7 SN - 0034-6748 DO - 10.1063/5.0086747 UR - https://m2.mtmt.hu/api/publication/32925515 ID - 32925515 N1 - National Laser-Initiated Transmutation Laboratory, University of Szeged, Szeged, 6720, Hungary Institute for Nuclear Research, Debrecen, 4026, Hungary ELI-ALPS Research Institute, ELI-HU Non-Profit Ltd., Szeged, 6728, Hungary Department of Optics and Quantum Electronics, University of Szeged, Szeged, 6720, Hungary Export Date: 27 July 2022 CODEN: RSINA Correspondence Address: Osvay, K.; National Laser-Initiated Transmutation Laboratory, Hungary; email: osvay@physx.u-szeged.hu LA - English DB - MTMT ER - TY - JOUR AU - Karsch, Leonhard AU - Pawelke, Jörg AU - Brand, Michael AU - Hans, Stefan AU - Hideghéty, Katalin AU - Jansen, Jeannette AU - Lessmann, Elisabeth AU - Löck, Steffen AU - Schürer, Michael AU - Schurig, Rico AU - Seco, Joao AU - Szabó, Emilia Rita AU - Beyreuther, Elke TI - Beam pulse structure and dose rate as determinants for the flash effect observed in zebrafish embryo JF - RADIOTHERAPY AND ONCOLOGY J2 - RADIOTHER ONCOL VL - 173 PY - 2022 SP - 49 EP - 54 PG - 6 SN - 0167-8140 DO - 10.1016/j.radonc.2022.05.025 UR - https://m2.mtmt.hu/api/publication/32868094 ID - 32868094 N1 - Helmholtz-Zentrum Dresden – Rossendorf (HZDR), Institute of Radiooncology - OncoRay, Germany OncoRay – National Center for Radiation Research in Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Helmholtz-Zentrum Dresden – Rossendorf, Germany Center for Regenerative Therapies TU Dresden (CRTD), Cluster of Excellence 'Physics of Life', Technische Universität Dresden, Germany ELI-ALPS, ELI-HU Non-Profit Ltd., Szeged, Hungary Oncotherapy Department, University of Szeged, Hungary Division of Biomedical Physics in Radiation Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany Helmholtz-Zentrum Dresden – Rossendorf, Institute of Radiation Physics, Germany Department of Radiotherapy and Radiation Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Germany German Cancer Consortium (DKTK), Partner Site Dresden, and German Cancer Research Center (DKFZ), Heidelberg, Germany National Center for Tumor Diseases Dresden (NCT/UCC), Germany, German Cancer Research Center (DKFZ), Heidelberg, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Helmholtz-Zentrum Dresden – Rossendorf, Dresden, Germany Faculty of Physics and Astronomy, Heidelberg University, Germany Cited By :10 Export Date: 14 March 2023 CODEN: RAOND Correspondence Address: Beyreuther, E.; OncoRay – National Center for Radiation Research in Oncology, Bautzner Landstraße 400, Germany; email: E.Beyreuther@hzdr.de Chemicals/CAS: proton, 12408-02-5, 12586-59-3; Protons Funding details: Horizon 2020 Framework Programme, H2020 Funding details: European Commission, EC Funding details: European Research Council, ERC Funding details: Deutsche Forschungsgemeinschaft, DFG, BR 1746/3, BR 1746/6 Funding details: Horizon 2020, 730983, 871124, GINOP-2.3.6-15-2015-00001 Funding details: European Regional Development Fund, ERDF Funding details: Helmholtz Association Funding text 1: This research was carried out at ELBE at the Helmholtz-Zentrum Dresden – Rossendorf e. V. a member of the Helmholtz Association. We would like to thank especially Pavel Evtushenko, Ulf Lehnert, Christoph Schneider and Peter Michel from the ELBE crew for support and their ongoing interest in our high-dose rate electron experiments. We thank Daniela Zöller for help with zebrafish embryo transfer and Marika Fischer, Sylvio Kunadt and Daniela Mögel from the animal facility for dedicated zebrafish care. Work by SH and MB is supported by project grants to MB of the German Research Foundation (Deutsche Forschungsgemeinschaft, project numbers BR 1746/3 and BR 1746/6), and an ERC advanced grant (Zf-BrainReg). The experimental part of the UPTD proton facility has received funding from the European Union's Horizon 2020 research and innovation program under grant agreement No.730983 (INSPIRE). We also thank the local IBA Team for supporting our proton Flash experiments. The ELI-ALPS project (GINOP-2.3.6-15-2015-00001) is supported by the European Union and co-financed by the European Regional Development Fund. KH and ERS has received funding from the European Union's Horizon 2020 research and innovation programme under grant agreement no 871124 Laserlab-Europe. JJ was supported by grants of the German-Israeli Helmholtz Research School in Cancer Biology – Cancer Transitional and Research Exchange Program (Cancer-TRAX) and by the Weizmann-Helmholtz Laboratory for Laser Matter Interaction (WHELMI). Funding text 2: This research was carried out at ELBE at the Helmholtz-Zentrum Dresden – Rossendorf e. V., a member of the Helmholtz Association. We would like to thank especially Pavel Evtushenko, Ulf Lehnert, Christoph Schneider and Peter Michel from the ELBE crew for support and their ongoing interest in our high-dose rate electron experiments. We thank Daniela Zöller for help with zebrafish embryo transfer and Marika Fischer, Sylvio Kunadt and Daniela Mögel from the animal facility for dedicated zebrafish care. Work by SH and MB is supported by project grants to MB of the German Research Foundation (Deutsche Forschungsgemeinschaft, project numbers BR 1746/3 and BR 1746/6), and an ERC advanced grant (Zf-BrainReg). The experimental part of the UPTD proton facility has received funding from the European Union’s Horizon 2020 research and innovation program under grant agreement No.730983 (INSPIRE). We also thank the local IBA Team for supporting our proton Flash experiments. The ELI-ALPS project (GINOP-2.3.6-15-2015-00001) is supported by the European Union and co-financed by the European Regional Development Fund. KH and ERS has received funding from the European Union's Horizon 2020 research and innovation programme under grant agreement no 871124 Laserlab-Europe. JJ was supported by grants of the German-Israeli Helmholtz Research School in Cancer Biology – Cancer Transitional and Research Exchange Program (Cancer-TRAX) and by the Weizmann-Helmholtz Laboratory for Laser Matter Interaction (WHELMI). LA - English DB - MTMT ER - TY - JOUR AU - Brunner, Szilvia AU - Varga, Dániel AU - Bozó, Renáta AU - Polanek, Róbert AU - Tőkés, Tünde AU - Szabó, Emilia Rita AU - Molnár, Réka AU - Gémes, Nikolett AU - Szebeni, Gábor AU - Puskás, László AU - Erdélyi, Miklós AU - Hideghéty, Katalin TI - Analysis of Ionizing Radiation Induced DNA Damage by Superresolution dSTORM Microscopy JF - PATHOLOGY AND ONCOLOGY RESEARCH J2 - PATHOL ONCOL RES VL - 27 PY - 2021 PG - 13 SN - 1219-4956 DO - 10.3389/pore.2021.1609971 UR - https://m2.mtmt.hu/api/publication/32487977 ID - 32487977 N1 - Funding details: Laserlab-Europe Funding details: European Commission, EC Funding details: Horizon 2020, 2017-1.2.1-NKP-2017-00002, 871124, NTP-NFTÖ-20-B-0354 Funding details: European Regional Development Fund, ERDF, GINOP-2.3.6-15-2015-00001 Funding text 1: This work was supported in part by the European Union and co-financed by the European Regional Development Fund through the ELI-ALPS project (GINOP-2.3.6-15-2015-00001), and in part by Horizon 2020, the EU Framework Programme for Research and Innovation under Grant Agreement No. 871124 Laserlab-Europe. The Confocal and superresolution dSTORM experiments and their evaluation were funded by the Hungarian BrainResearch Program (2017-1.2.1-NKP-2017-00002) and the National Young Talent Scholarship programme (NTP-NFTÖ-20-B-0354). LA - English DB - MTMT ER - TY - JOUR AU - Hideghéty, Katalin AU - Tőkés, Tünde AU - Polanek, Róbert AU - Szabó, Emilia Rita TI - Ígéretes sugárkezelési technikák a klinikai bevezetés küszöbén: mikronyaláb- és villanás besugárzás JF - KLINIKAI ONKOLÓGIA J2 - KLINIKAI ONKOLÓGIA VL - 8 PY - 2021 IS - 1 SP - 71 EP - 78 PG - 8 SN - 2064-5058 UR - https://m2.mtmt.hu/api/publication/32013749 ID - 32013749 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Pawelke, Jörg AU - Brand, Michael AU - Hans, Stefan AU - Hideghéty, Katalin AU - Karsch, Leonhard AU - Lessmann, Elisabeth AU - Löck, Steffen AU - Schürer, Michael AU - Szabó, Emilia Rita AU - Beyreuther, Elke TI - Electron dose rate and oxygen depletion protect zebrafish embryos from radiation damage JF - RADIOTHERAPY AND ONCOLOGY J2 - RADIOTHER ONCOL VL - 158 PY - 2021 SP - 7 EP - 12 PG - 6 SN - 0167-8140 DO - 10.1016/j.radonc.2021.02.003 UR - https://m2.mtmt.hu/api/publication/31903931 ID - 31903931 N1 - Helmholtz-Zentrum Dresden – Rossendorf (HZDR), Institute of Radiooncology – OncoRay, Germany OncoRay – National Center for Radiation Research in Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Helmholtz-Zentrum Dresden – Rossendorf, Germany Center for Regenerative Therapies TU Dresden (CRTD), and Cluster of Excellence 'Physics of Life', Technische Universität Dresden, Germany ELI-ALPS, ELI-HU Non-Profit Ltd., Szeged, Hungary Oncotherapy Department, University of Szeged, Szeged, Hungary Helmholtz-Zentrum Dresden – Rossendorf, Institute of Radiation Physics, Germany Department of Radiotherapy and Radiation Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Germany German Cancer Consortium (DKTK), Partner Site Dresden, and German Cancer Research Center (DKFZ), Heidelberg, Germany National Center for Tumor Diseases (NCT), Partner Site Dresden, Germany Cited By :4 Export Date: 14 February 2022 CODEN: RAOND Correspondence Address: Beyreuther, E.Bautzner Landstraße 400, Germany; email: E.Beyreuther@hzdr.de LA - English DB - MTMT ER - TY - JOUR AU - Polanek, Róbert AU - Hafiz, Nasr Abdelrahman Mohamed AU - Lécz, Zsolt AU - Papp, Dániel AU - Kamperidis, Christos AU - Brunner, Szilvia AU - Szabó, Emilia Rita AU - Tőkés, Tünde AU - Hideghéty, Katalin TI - 1 kHz laser accelerated electron beam feasible for radiotherapy uses: A PIC–Monte Carlo based study JF - NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT J2 - NUCL INSTRUM METH A VL - 987 PY - 2021 PG - 7 SN - 0168-9002 DO - 10.1016/j.nima.2020.164841 UR - https://m2.mtmt.hu/api/publication/31791845 ID - 31791845 N1 - ELI-ALPS, ELI-HU Non-Profit Ltd. Wolfgang Sandner u. 3, Szeged, H-6728, Hungary National Laboratory on High Power Laser and Physics, SIOM, CAS, Shanghai, 201800, China Department of Plasma and Nuclear Fusion, Nuclear Research Center, Atomic Energy Authority, Abu-Zabal, 13759, Egypt University of Szeged, Faculty of Medicine, Department of Oncotherapy, Korányi fasor 12., Szeged, H-6720, Hungary Cited By :10 Export Date: 15 May 2023 CODEN: NIMAE Correspondence Address: Polanek, R.; ELI-ALPS, Hungary; email: robert.polanek@eli-alps.hu Funding details: Horizon 2020 Framework Programme, H2020 Funding details: College of Arts and Sciences, University of Nebraska-Lincoln, CAS Funding details: European Commission, EC Funding details: Chinese Academy of Sciences, CAS, 181231KYSB20170022 Funding details: Horizon 2020, 654148, 871124 Funding details: European Regional Development Fund, FEDER, GINOP-2.3.6-15-2015-00001 Funding text 1: This work was supported in part by the European Union and co-financed by the European Regional Development Fund through the ELI-ALPS project (GINOP-2.3.6-15-2015-00001), and in part by Horizon 2020, the EU Framework Programme for Research and Innovation under Grant Agreement No. 654148 and No. 871124 Laserlab-Europe. N. A. M. H. acknowledges the President International Fellowship Initiative (PIFI) of the Chinese Academy of Sciences; the International Partnership Program (181231KYSB20170022) of CAS; the Inter-Governmental Science and Technology Cooperation of MOST. Funding text 2: This work was supported in part by the European Union and co-financed by the European Regional Development Fund through the ELI-ALPS project (GINOP-2.3.6-15-2015-00001), and in part by Horizon 2020 , the EU Framework Programme for Research and Innovation under Grant Agreement No. 654148 and No. 871124 Laserlab-Europe. Funding text 3: N. A. M. H. acknowledges the President International Fellowship Initiative (PIFI) of the Chinese Academy of Sciences; the International Partnership Program (181231KYSB20170022) of CAS; the Inter-Governmental Science and Technology Cooperation of MOST. LA - English DB - MTMT ER - TY - JOUR AU - Brack, Florian-Emanuel AU - Kroll, Florian AU - Gaus, Lennart AU - Bernert, Constantin AU - Beyreuther, Elke AU - Cowan, Thomas E. AU - Karsch, Leonhard AU - Kraft, Stephan AU - Kunz-Schughart, Leoni A. AU - Lessmann, Elisabeth AU - Metzkes-Ng, Josefine AU - Obst-Huebl, Lieselotte AU - Pawelke, Joerg AU - Rehwald, Martin AU - Schlenvoigt, Hans-Peter AU - Schramm, Ulrich AU - Sobiella, Manfred AU - Szabó, Emilia Rita AU - Ziegler, Tim AU - Zeil, Karl TI - Spectral and spatial shaping of laser-driven proton beams using a pulsed high-field magnet beamline (vol 10, 9118, 2020) JF - SCIENTIFIC REPORTS J2 - SCI REP VL - 10 PY - 2020 IS - 1 PG - 1 SN - 2045-2322 DO - 10.1038/s41598-020-69874-3 UR - https://m2.mtmt.hu/api/publication/32677301 ID - 32677301 LA - English DB - MTMT ER - TY - JOUR AU - Brack, Florian-Emanuel AU - Kroll, Florian AU - Gaus, Lennart AU - Bernert, Constantin AU - Beyreuther, Elke AU - Cowan, Thomas E. AU - Karsch, Leonhard AU - Kraft, Stephan AU - Kunz-Schughart, Leoni A. AU - Lessmann, Elisabeth AU - Metzkes-Ng, Josefine AU - Obst-Huebl, Lieselotte AU - Pawelke, Jörg AU - Rehwald, Martin AU - Schlenvoigt, Hans-Peter AU - Schramm, Ulrich AU - Sobiella, Manfred AU - Szabó, Emilia Rita AU - Ziegler, Tim AU - Zeil, Karl TI - Spectral and spatial shaping of laser-driven proton beams using a pulsed high-field magnet beamline JF - SCIENTIFIC REPORTS J2 - SCI REP VL - 10 PY - 2020 IS - 1 PG - 12 SN - 2045-2322 DO - 10.1038/s41598-020-65775-7 UR - https://m2.mtmt.hu/api/publication/31903945 ID - 31903945 N1 - Helmholtz-Zentrum Dresden – Rossendorf, Dresden, 01328, Germany Technische Universität Dresden, Dresden, 01062, Germany OncoRay – National Center for Radiation Research in Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, TU Dresden and Helmholtz-Zentrum Dresden–Rossendorf, Dresden, Germany National Center for Tumor Diseases (NCT), partner site Dresden, Dresden, Germany ELI-ALPS, ELI-HU Non-Profit Ltd., Wolfgang Sandner utca 3, Szeged, H-6728, Hungary Lawrence Berkeley National Laboratory, Berkeley, United States Cited By :20 Export Date: 13 March 2023 Correspondence Address: Brack, F.-E.; Helmholtz-Zentrum Dresden – RossendorfGermany; email: f.brack@hzdr.de Funding details: 654148, 871124, GINOP-2.3.6-15-2015-00001 Funding details: European Commission, EC Funding details: European Regional Development Fund, ERDF Funding text 1: S. Bock, R. Gebhardt, U. Helbig and T. Püschel are highly acknowledged for their laser support. We thank T. Hermannsdörfer, S. Zherlitsyn and the workshop of the High Magnetic Field Laboratory Dresden (HLD) for their advice and the manufacturing of the solenoids. We thank NJ Hartley for his help preparing the paper. We also thank M. Wondrak for her technical assistance with spheroid preparation. The work was partially supported by EC Horizon 2020 LASERLAB-EUROPE/LEPP (Contract No. 654148 and 871124). The ELI-ALPS project (GINOP-2.3.6-15-2015-00001) is supported by the European Union and co-financed by the European Regional Development Fund. LA - English DB - MTMT ER -