@CONFERENCE{MTMT:34154565, title = {Radiosensitizing effect of metal nanoparticles in combination with histone deacetylase inhibitors}, url = {https://m2.mtmt.hu/api/publication/34154565}, author = {Igaz, Nóra and Szőke, Krisztina and Bocz, Csenge and Kovács, Dávid and Rónavári, Andrea and Szabó, Emilia Rita and Polanek, Róbert and Buhala, Andrea and Vizler, Csaba and Tiszlavicz, László and Rázga, Zsolt and Hideghéty, Katalin and Kónya, Zoltán and Csontné Kiricsi, Mónika}, booktitle = {FAMÉ 2023}, unique-id = {34154565}, year = {2023}, pages = {75-76}, orcid-numbers = {Igaz, Nóra/0000-0003-1580-4397; Rónavári, Andrea/0000-0001-7054-0975; Szabó, Emilia Rita/0000-0003-3611-2066; Polanek, Róbert/0000-0003-3645-8331; Tiszlavicz, László/0000-0003-1134-6587; Rázga, Zsolt/0000-0003-4717-8482; Hideghéty, Katalin/0000-0001-7080-2365; Kónya, Zoltán/0000-0002-9406-8596; Csontné Kiricsi, Mónika/0000-0002-8416-2052} } @article{MTMT:34028192, title = {Hybrid acceleration of compact ion bunches by few-cycle laser pulses in gas jets of two atomic species}, url = {https://m2.mtmt.hu/api/publication/34028192}, author = {Lécz, Zsolt and Polanek, Róbert and Andreev, Alexander and Sharma, Ashutosh and Papp, Dániel and Hafiz, Nasr Abdelrahman Mohamed and Kamperidis, Christos}, doi = {10.1103/PhysRevResearch.5.023169}, journal-iso = {PRRESEARCH}, journal = {PHYSICAL REVIEW RESEARCH}, volume = {5}, unique-id = {34028192}, year = {2023}, eissn = {2643-1564}, orcid-numbers = {Lécz, Zsolt/0000-0001-5968-8012; Polanek, Róbert/0000-0003-3645-8331; Andreev, Alexander/0000-0002-1948-8814; Sharma, Ashutosh/0000-0001-9021-4296; Papp, Dániel/0000-0002-7954-3686; Hafiz, Nasr Abdelrahman Mohamed/0000-0002-6597-571X; Kamperidis, Christos/0000-0002-0360-7671} } @article{MTMT:33134572, title = {Application of Lacunarity for Quantification of Single Molecule Localization Microscopy Images}, url = {https://m2.mtmt.hu/api/publication/33134572}, author = {H. Kovács, Bálint Barna and Varga, Dániel and Sebők, Dániel and Majoros, Hajnalka and Polanek, Róbert and Pankotai, Tibor and Hideghéty, Katalin and Kukovecz, Ákos and Erdélyi, Miklós}, doi = {10.3390/cells11193105}, journal-iso = {CELLS-BASEL}, journal = {CELLS}, volume = {11}, unique-id = {33134572}, abstract = {The quantitative analysis of datasets achieved by single molecule localization microscopy is vital for studying the structure of subcellular organizations. Cluster analysis has emerged as a multi-faceted tool in the structural analysis of localization datasets. However, the results it produces greatly depend on the set parameters, and the process can be computationally intensive. Here we present a new approach for structural analysis using lacunarity. Unlike cluster analysis, lacunarity can be calculated quickly while providing definitive information about the structure of the localizations. Using simulated data, we demonstrate how lacunarity results can be interpreted. We use these interpretations to compare our lacunarity analysis with our previous cluster analysis-based results in the field of DNA repair, showing the new algorithm’s efficiency.}, year = {2022}, eissn = {2073-4409}, orcid-numbers = {Varga, Dániel/0000-0003-0391-5057; Sebők, Dániel/0000-0001-9769-5598; Majoros, Hajnalka/0000-0003-2020-971X; Polanek, Róbert/0000-0003-3645-8331; Pankotai, Tibor/0000-0001-9810-5465; Hideghéty, Katalin/0000-0001-7080-2365; Kukovecz, Ákos/0000-0003-0716-9557; Erdélyi, Miklós/0000-0002-9501-5752} } @article{MTMT:32487977, title = {Analysis of Ionizing Radiation Induced DNA Damage by Superresolution dSTORM Microscopy}, url = {https://m2.mtmt.hu/api/publication/32487977}, author = {Brunner, Szilvia and Varga, Dániel and Bozó, Renáta and Polanek, Róbert and Tőkés, Tünde and Szabó, Emilia Rita and Molnár, Réka and Gémes, Nikolett and Szebeni, Gábor and Puskás, László and Erdélyi, Miklós and Hideghéty, Katalin}, doi = {10.3389/pore.2021.1609971}, journal-iso = {PATHOL ONCOL RES}, journal = {PATHOLOGY AND ONCOLOGY RESEARCH}, volume = {27}, unique-id = {32487977}, issn = {1219-4956}, year = {2021}, eissn = {1532-2807}, orcid-numbers = {Varga, Dániel/0000-0003-0391-5057; Bozó, Renáta/0000-0003-4242-2474; Polanek, Róbert/0000-0003-3645-8331; Tőkés, Tünde/0000-0002-0587-7886; Szabó, Emilia Rita/0000-0003-3611-2066; Molnár, Réka/0000-0002-3128-825X; Szebeni, Gábor/0000-0002-6998-5632; Erdélyi, Miklós/0000-0002-9501-5752; Hideghéty, Katalin/0000-0001-7080-2365} } @article{MTMT:32013749, title = {Ígéretes sugárkezelési technikák a klinikai bevezetés küszöbén: mikronyaláb- és villanás besugárzás}, url = {https://m2.mtmt.hu/api/publication/32013749}, author = {Hideghéty, Katalin and Tőkés, Tünde and Polanek, Róbert and Szabó, Emilia Rita}, journal-iso = {KLINIKAI ONKOLÓGIA}, journal = {KLINIKAI ONKOLÓGIA}, volume = {8}, unique-id = {32013749}, issn = {2064-5058}, year = {2021}, pages = {71-78}, orcid-numbers = {Hideghéty, Katalin/0000-0001-7080-2365; Tőkés, Tünde/0000-0002-0587-7886; Polanek, Róbert/0000-0003-3645-8331; Szabó, Emilia Rita/0000-0003-3611-2066} } @article{MTMT:31791845, title = {1 kHz laser accelerated electron beam feasible for radiotherapy uses: A PIC–Monte Carlo based study}, url = {https://m2.mtmt.hu/api/publication/31791845}, author = {Polanek, Róbert and Hafiz, Nasr Abdelrahman Mohamed and Lécz, Zsolt and Papp, Dániel and Kamperidis, Christos and Brunner, Szilvia and Szabó, Emilia Rita and Tőkés, Tünde and Hideghéty, Katalin}, doi = {10.1016/j.nima.2020.164841}, journal-iso = {NUCL INSTRUM METH A}, journal = {NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT}, volume = {987}, unique-id = {31791845}, issn = {0168-9002}, year = {2021}, eissn = {1872-9576}, orcid-numbers = {Polanek, Róbert/0000-0003-3645-8331; Hafiz, Nasr Abdelrahman Mohamed/0000-0002-6597-571X; Lécz, Zsolt/0000-0001-5968-8012; Papp, Dániel/0000-0002-7954-3686; Kamperidis, Christos/0000-0002-0360-7671; Szabó, Emilia Rita/0000-0003-3611-2066; Tőkés, Tünde/0000-0002-0587-7886; Hideghéty, Katalin/0000-0001-7080-2365} } @mastersthesis{MTMT:31956663, title = {Dosimetric Analysis of a Laser Accelerated Electron Beam and Optimization of FBX Chemical Dosimeter [Lézer-plazma gyorsította elektronnyaláb dozimetriai jellemzése valamint egy az FBX típusú kémiai doziméter továbbfejlesztése]}, url = {https://m2.mtmt.hu/api/publication/31956663}, author = {Polanek, Róbert}, doi = {10.14232/phd.10712}, publisher = {SZTE}, unique-id = {31956663}, year = {2020}, orcid-numbers = {Polanek, Róbert/0000-0003-3645-8331} } @article{MTMT:31655754, title = {Dose-dependent Changes After Proton and Photon Irradiation in a Zebrafish Model}, url = {https://m2.mtmt.hu/api/publication/31655754}, author = {Brunner, Szilvia and Tőkés, Tünde and Szabó, Emilia Rita and Polanek, Róbert and Szabó, Zoltán Imre and Reisz, Zita and Konczné Gubán, Barbara and Szijártó, András Lajos and Michael, Brand and Stefan, Hans and Leonhard, Karsch and Elisabeth, Lessmann and Jörg, Pawelke and Michael, Schürer and Elke, Beyreuther and Hideghéty, Katalin}, doi = {10.21873/anticanres.14633}, journal-iso = {ANTICANCER RES}, journal = {ANTICANCER RESEARCH}, volume = {40}, unique-id = {31655754}, issn = {0250-7005}, year = {2020}, eissn = {1791-7530}, pages = {6123-6135}, orcid-numbers = {Tőkés, Tünde/0000-0002-0587-7886; Szabó, Emilia Rita/0000-0003-3611-2066; Polanek, Róbert/0000-0003-3645-8331; Szabó, Zoltán Imre/0000-0001-8278-8038; Hideghéty, Katalin/0000-0001-7080-2365} } @article{MTMT:31392882, title = {Improved FBX chemical dosimeter system with enhanced radiochemical yield for reference dosimetry in radiobiology and radiotherapy research}, url = {https://m2.mtmt.hu/api/publication/31392882}, author = {Polanek, Róbert and Varga, Zoltán and Fodor, Emese and Brunner, Szilvia and Szabó, Emilia Rita and Tőkés, Tünde and Hideghéty, Katalin}, doi = {10.1016/j.radphyschem.2020.108899}, journal-iso = {RADIAT PHYS CHEM}, journal = {RADIATION PHYSICS AND CHEMISTRY: THE JOURNAL FOR RADIATION PHYSICS RADIATION CHEMISTRY AND RADIATION PROCESSING}, volume = {174}, unique-id = {31392882}, issn = {0969-806X}, abstract = {Radiation dosimetry plays important role in the reproducibility of radiobiology experiments, in the replicability of results, as well as in the successful and safe use of radiotherapy procedures. The consistency and accuracy of the applied dosimetry methods pre-define the outcomes of these applications. This paper presents a version of the well-known ferrous sulphate – benzoic acid – xylenol orange (FBX) chemical dosimeter with improved sensitivity, accuracy and precision. Sensitivity is increased due to a slight modification in composition and the preparation procedures. We use stock solutions for the preparation of the dosimeter solution, which consists of 1 mM ferrous sulphate and 16 mM benzoic acid with 0.25 mM xylenol orange added post-irradiation. The nonlinear response to the absorbed dose of this system is eliminated by the increased ferrous sulphate concentration, permitting the calculation of the absorbed dose by a linear relationship between the absorbed dose and the optical absorbance of the solution. The measured chemical yield of our dosimeter is 9.08⋅10−6mol/J for 6 MV photon beams and 6.42⋅10−6mol/J for 250 kVp x-rays. This is a 24% enhancement over the original FBX solution, which permits a finer dose resolution. The accuracy and precision of our method is assured by a well-designed and consistently used practice. A custom designed multipurpose PMMA slab phantom was used for irradiation in reference conditions. This phantom can be used for irradiation in reference conditions of dosimetric solutions, dosimetric films and chemical or biological samples. The combined standard uncertainty of this system is 1.12%, which can be improved by using an appropriate temperature correction factor. Furthermore, a working protocol has been established which allows dosimetry measurements using less than 1 mL dosimetric solutions.}, keywords = {FBX chemical dosimeter; PMMA slab Phantom; Enhanced radiochemical yield; Reference dosimetry}, year = {2020}, eissn = {1879-0895}, orcid-numbers = {Polanek, Róbert/0000-0003-3645-8331; Varga, Zoltán/0000-0001-8537-6282; Szabó, Emilia Rita/0000-0003-3611-2066; Tőkés, Tünde/0000-0002-0587-7886; Hideghéty, Katalin/0000-0001-7080-2365} } @article{MTMT:31339600, title = {A feasibility study of zebrafish embryo irradiation with laser-accelerated protons}, url = {https://m2.mtmt.hu/api/publication/31339600}, author = {Rösch, Thomas F. and Szabó, Zoltán Imre and Haffa, Daniel and Bin, Jianhui and Brunner, Szilvia and Englbrecht, Franz S. and Friedl, Anna A. and Gao, Ying and Hartmann, Jens and Hilz, Peter and Kreuzer, Christian and Lindner, Florian H. and Ostermayr, Tobias M. and Polanek, Róbert and Speicher, Martin and Szabó, Emilia Rita and Taray, Derya and Tőkés, Tünde and Würl, Matthias and Parodi, Katia and Hideghéty, Katalin and Schreiber, Jörg}, doi = {10.1063/5.0008512}, journal-iso = {REV SCI INSTRUM}, journal = {REVIEW OF SCIENTIFIC INSTRUMENTS}, volume = {91}, unique-id = {31339600}, issn = {0034-6748}, year = {2020}, eissn = {1089-7623}, orcid-numbers = {Szabó, Zoltán Imre/0000-0001-8278-8038; Polanek, Róbert/0000-0003-3645-8331; Szabó, Emilia Rita/0000-0003-3611-2066; Tőkés, Tünde/0000-0002-0587-7886; Hideghéty, Katalin/0000-0001-7080-2365} }