@article{MTMT:32575842,
	title = {Ponatinib Exerts an Inhibitory Effect on Collagen-induced Platelet Aggregation and Generation of Coated-Platelets},
	url = {https://m2.mtmt.hu/api/publication/32575842},
	author = {Mezei, Gabriella and Batár, Péter and Kozma, Laura and Illés, Árpád and Kappelmayer, János and Bekéné Debreceni, Ildikó},
	doi = {10.21873/anticanres.15300},
	journal-iso = {ANTICANCER RES},
	journal = {ANTICANCER RESEARCH},
	volume = {41},
	unique-id = {32575842},
	issn = {0250-7005},
	abstract = {Background/Aim: BCR-ABL tyrosine kinase inhibitors (TKIs) are exceptionally effective drugs in the treatment of chronic myeloid leukemia, nevertheless, TKIs have also an effect on platelets. We aimed to investigate the effect of a third-generation TKI, ponatinib on platelet functions. Materials and Methods: Collagen-induced platelet aggregation and coated-platelet formation were examined using in vitro and in ex vivo samples of patients on ponatinib therapy. Results: In platelet rich plasma of healthy volunteers, ponatinib at a supra- therapeutic concentration (1,000 nM) significantly impaired collagen induced platelet aggregation (p <= 0.01) and reduced the formation of coated-platelets at 150 nM ponatinib concentration ( p <= 0.05). In addition, upon glycoprotein VI (GPVI) receptor activation, a significantly lower percentage of PAC1 binding platelets (p <= 0.05) was observed at 1,000 nM final concentration of ponatinib. Platelets, isolated from patients on ponatinib therapy showed impaired collagen elicited aggregation response, already in pre-dose samples compared to healthy donors. Conclusion: The therapeutic concentration of ponatinib impairs platelet activation processes elicited by GPVI receptor agonists.},
	keywords = {Platelet function; Laboratory testing; Ponatinib therapy},
	year = {2021},
	eissn = {1791-7530},
	pages = {4867-4874}
}

@article{MTMT:32285360,
	title = {A krónikus myeloid leukaemia tirozin-kináz-gátló kezelésének mellékhatásai és azok gyakorlati ellátása = Practical management of side effects of tyrosine kinase inhibitor therapy in chronic myeloid leukemia},
	url = {https://m2.mtmt.hu/api/publication/32285360},
	author = {Mezei, Gabriella and Illés, Árpád and Batár, Péter},
	doi = {10.1556/650.2021.32177},
	journal-iso = {ORV HETIL},
	journal = {ORVOSI HETILAP},
	volume = {162},
	unique-id = {32285360},
	issn = {0030-6002},
	year = {2021},
	eissn = {1788-6120},
	pages = {1198-1207}
}

@article{MTMT:31385279,
	title = {Imidazo[1,2-b]pyrazole-7-Carboxamide Derivative Induces Differentiation-Coupled Apoptosis of Immature Myeloid Cells Such as Acute Myeloid Leukemia and Myeloid-Derived Suppressor Cells},
	url = {https://m2.mtmt.hu/api/publication/31385279},
	author = {Kotogány, Edit and Balog, József Ágoston and Nagy, Lajos I. and Alföldi, Róbert and Bertagnolo, Valeria and Brugnoli, Federica and Demjén, András and Kovács, Anita Kármen and Batár, Péter and Mezei, Gabriella and Szabó, Renáta and Kanizsai, Iván and Varga, Csaba and Puskás, László and Szebeni, Gábor},
	doi = {10.3390/ijms21145135},
	journal-iso = {INT J MOL SCI},
	journal = {INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES},
	volume = {21},
	unique-id = {31385279},
	issn = {1661-6596},
	year = {2020},
	eissn = {1422-0067},
	orcid-numbers = {Kovács, Anita Kármen/0000-0001-9805-1647; Varga, Csaba/0000-0002-2678-665X; Szebeni, Gábor/0000-0002-6998-5632}
}

@article{MTMT:32005205,
	title = {Dasatinib inhibits coated-platelet generation in patients with chronic myeloid leukemia},
	url = {https://m2.mtmt.hu/api/publication/32005205},
	author = {Mezei, Gabriella and Bekéné Debreceni, Ildikó and Kerenyi, Adrienne and Reményi, Gyula and Szász, Róbert and Illés, Árpád and Kappelmayer, János and Batár, Péter},
	doi = {10.1080/09537104.2018.1501470},
	journal-iso = {PLATELETS},
	journal = {PLATELETS},
	volume = {30},
	unique-id = {32005205},
	issn = {0953-7104},
	year = {2019},
	eissn = {1369-1635},
	pages = {836-843},
	orcid-numbers = {Szász, Róbert/0000-0003-1343-6017}
}

@article{MTMT:31189289,
	title = {Dasatinib Inhibits Procoagulant and Clot Retracting Activities of Human Platelets},
	url = {https://m2.mtmt.hu/api/publication/31189289},
	author = {Bekéné Debreceni, Ildikó and Mezei, Gabriella and Batár, Péter and Illés, Árpád and Kappelmayer, János},
	doi = {10.3390/ijms20215430},
	journal-iso = {INT J MOL SCI},
	journal = {INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES},
	volume = {20},
	unique-id = {31189289},
	issn = {1661-6596},
	year = {2019},
	eissn = {1422-0067}
}

@article{MTMT:3111420,
	title = {Az akut myeloid leukaemia gyógyszeres kezelése. Jelenlegi lehetőségek, jövőbeli kilátások},
	url = {https://m2.mtmt.hu/api/publication/3111420},
	author = {Telek, Béla and Rejtő, László and Batár, Péter and Miltényi, Zsófia and Reményi, Gyula and Simon, Zsófia Zsuzsanna and Ujj, Zsófia Ágnes and Mezei, Gabriella and Szász, Róbert and Kiss, Attila and Udvardy, Miklós and Illés, Árpád},
	doi = {10.1556/650.2016.30433},
	journal-iso = {ORV HETIL},
	journal = {ORVOSI HETILAP},
	volume = {157},
	unique-id = {3111420},
	issn = {0030-6002},
	keywords = {Aged; Age Factors; Middle Aged; Humans; Survival Analysis; Antineoplastic Combined Chemotherapy Protocols/*therapeutic use; Quality of Life; Drug Administration Schedule; Treatment Outcome; Cytarabine/administration & dosage; Karnofsky Performance Status; Molecular targeted therapy; Daunorubicin/administration & dosage; Leukemia, Myeloid, Acute/*drug therapy; *Induction Chemotherapy/methods},
	year = {2016},
	eissn = {1788-6120},
	pages = {843-848},
	orcid-numbers = {Szász, Róbert/0000-0003-1343-6017}
}

@article{MTMT:1463342,
	title = {Haematológiai és haemostasis paraméterek változása transjugularis intrahepaticus portosystemas shunt (TIPS) hatására},
	url = {https://m2.mtmt.hu/api/publication/1463342},
	author = {Papp, Mária and Mezei, Gabriella and Udvardy, Miklós and Altorjay, István},
	journal-iso = {ORV HETIL},
	journal = {ORVOSI HETILAP},
	volume = {144},
	unique-id = {1463342},
	issn = {0030-6002},
	keywords = {Aged; Adult; Female; Middle Aged; Male; Humans; metabolism; BLOOD; FIBRINOGEN; ARTICLE; human; Predictive Value of Tests; Prognosis; Retrospective Studies; Leukocyte Count; Platelet Count; Equipment Failure; retrospective study; prediction and forecasting; thrombocyte count; Prothrombin Time; equipment; portal hypertension; partial thromboplastin time; Portasystemic Shunt, Transjugular Intrahepatic; Hypertension, Portal; portosystemic anastomosis; hypersplenism},
	year = {2003},
	eissn = {1788-6120},
	pages = {1341-1345},
	orcid-numbers = {Papp, Mária/0000-0003-3662-4010}
}

@article{MTMT:1138705,
	title = {Molekuláris biológiai vizsgálatok kronikus lymphoid leukaemiában [Molecular biology examination in chronic lymphocytic leukemia]},
	url = {https://m2.mtmt.hu/api/publication/1138705},
	author = {Telek, Béla and Rejtő, László and Mezei, Gabriella and Karászi, Éva and Kappelmayer, János and Balázs, Margit and Kiss, Attila and Ujj, G and Rak, K and Udvardy, Miklós},
	journal-iso = {ORV HETIL},
	journal = {ORVOSI HETILAP},
	volume = {142},
	unique-id = {1138705},
	issn = {0030-6002},
	year = {2001},
	eissn = {1788-6120},
	pages = {833-837}
}

@article{MTMT:34484146,
	title = {A krónikus lymphoid leukaemia biológiája},
	url = {https://m2.mtmt.hu/api/publication/34484146},
	author = {Mezei, Gabriella and Karászi, Éva and Telek, Béla and Ujj, György and Rejtő, László and Kiss, Attila and Rácz, Klára and Udvardy, Miklós and Rák, Kálmán},
	journal-iso = {MBA},
	journal = {MAGYAR BELORVOSI ARCHIVUM},
	volume = {53},
	unique-id = {34484146},
	issn = {0133-5464},
	year = {2000},
	pages = {103-107}
}

@article{MTMT:1138698,
	title = {Fluoreszcencia in situ hibridizációval szerzett tapasztalataink a krónikus myeloid leukaemia diagnosztikájában és követésében},
	url = {https://m2.mtmt.hu/api/publication/1138698},
	author = {Rejtő, László and Balázs, Margit and Ádány, Róza and Rak, K and Telek, Béla and Kiss, Attila and Ujj, G and Mezei, Gabriella and Balogh, E and Udvardy, Miklós},
	journal-iso = {ORV HETIL},
	journal = {ORVOSI HETILAP},
	volume = {141},
	unique-id = {1138698},
	issn = {0030-6002},
	year = {2000},
	eissn = {1788-6120},
	pages = {2133-2137}
}