@article{MTMT:34334696,
	title = {Phosphoryl- or phosphinoyl-functionalized benzo[de]isoquinolinones: Synthesis, experimental design, mechanism and biological activity},
	url = {https://m2.mtmt.hu/api/publication/34334696},
	author = {Rávai, Bettina and Popovics-Tóth, Nóra and Lakné Komka, Kinga and Csontos, István and Szokol, Bálint and Őrfi, Zoltán and Őrfi, László and Bálint, Erika},
	doi = {10.1039/D3RE00489A},
	journal-iso = {REACT CHEM ENG},
	journal = {REACTION CHEMISTRY & ENGINEERING},
	volume = {9},
	unique-id = {34334696},
	issn = {2058-9883},
	abstract = {A propylphosphonic anhydride (T3P®)-mediated new multicomponent method was developed for the synthesis of benzo[de]isoquinolinones bearing a phosphonate or a phosphine oxide moiety as a new family of compounds. The one-pot...},
	year = {2024},
	eissn = {2058-9883},
	pages = {583-593},
	orcid-numbers = {Lakné Komka, Kinga/0000-0001-5461-1278; Csontos, István/0000-0002-6858-1388; Őrfi, Zoltán/0000-0001-6099-2206; Őrfi, László/0000-0001-6149-2385; Bálint, Erika/0000-0002-5107-7089}
}

@article{MTMT:33555305,
	title = {Three-Component Reaction of 3-Formyl-6-Methylchromone, Primary Amines, and Secondary Phosphine Oxides: A Synthetic and Mechanistic Study},
	url = {https://m2.mtmt.hu/api/publication/33555305},
	author = {Popovics-Tóth, Nóra and Bao, Trinh Dang Tran and Tajti, Ádám and Mátravölgyi, Béla and Kelemen, Zsolt and Perdih, Franc and Hackler, László and Puskás, László G. and Bálint, Erika},
	doi = {10.1021/acsomega.2c07333},
	journal-iso = {ACS OMEGA},
	journal = {ACS OMEGA},
	volume = {8},
	unique-id = {33555305},
	issn = {2470-1343},
	abstract = {A fast, mild, and efficient catalyst-free approach has been developed for the synthesis of chromonyl-substituted alpha-aminophosphine oxides by the three-component reaction of 3-formyl-6-methylchromone, primary amines, and secondary phosphine oxides at ambient temperature. Carrying out the reaction with aliphatic amines or aminoalcohols at a higher temperature (80 degrees C), phosphinoyl-functionalized 3-aminomethylene chromanones were formed instead of the corresponding chromonyl-substituted alpha-aminophosphine oxides. No reaction occurred when 3-formyl-6-methylchromone and secondary phosphine oxides were reacted with aromatic amines in the absence of any catalyst. Applying a basic catalyst, the formation of the phosphinoyl-functionalized 3-aminomethylene chromanones was observed; however, the reaction was not complete. Detailed experimental and quantum chemical studies were performed to study the transformation. Moreover, the in vitro cytotoxicity of phosphinoyl-functionalized 3-aminomethylene chromanones was also investigated in three different cell lines, such as human lung adenocarcinoma (A549), mouse fibroblast (NIH/3T3), and human promyelocytic leukemia (HL60) cells. Several derivatives showed modest activity against the human promyelocytic leukemia (HL60) cell line.},
	year = {2023},
	eissn = {2470-1343},
	pages = {2698-2711},
	orcid-numbers = {Mátravölgyi, Béla/0000-0001-8782-7972; Kelemen, Zsolt/0000-0002-4787-9804; Perdih, Franc/0000-0002-8416-7291; Bálint, Erika/0000-0002-5107-7089}
}

@article{MTMT:34071072,
	title = {Microwave-assisted synthesis of α-aminophosphonate-chromone hybrids using Kabachnik-Fields Reaction},
	url = {https://m2.mtmt.hu/api/publication/34071072},
	author = {Szabó, Kármen and Akali, Rama and Tajti, Ádám and Popovics-Tóth, Nóra and Bálint, Erika},
	doi = {10.24820/ark.5550190.p011.887},
	journal-iso = {ARKIVOC},
	journal = {ARKIVOC},
	unique-id = {34071072},
	issn = {1551-7012},
	abstract = {An efficient, practical, and green approach for the synthesis of alpha-aminophosphonates incorporating a chromone moiety by the one-pot Kabachnik-Fields reaction has been developed. The three-component reactions of 3-formylchromones, primary amines and dialkyl phosphites was carried out in short reaction times in the absence of any catalyst or solvent under microwave irradiation. The method developed did not require column chromatographic separation since the products could be recovered from the reaction mixture by simple filtration. The method developed could be applied to a range of primary amines and dialkyl phosphites, which confirmed the large scope and functional-group tolerance. [GRAPHICS] .},
	keywords = {SERIES; phosphonates; DRUG DISCOVERY; CHROMONE; Kabachnik-Fields reaction; ENAMINONES; Three-component reaction; biological evaluations; alpha-Aminophosphonate; PRIVILEGED SCAFFOLD; MEDIATED DOMINO},
	year = {2022},
	eissn = {1551-7004},
	pages = {256-271},
	orcid-numbers = {Szabó, Kármen/0009-0005-7734-1932; Bálint, Erika/0000-0002-5107-7089}
}

@article{MTMT:33190219,
	title = {Multicomponent Synthesis of Potentially Biologically Active Heterocycles Containing a Phosphonate or a Phosphine Oxide Moiety},
	url = {https://m2.mtmt.hu/api/publication/33190219},
	author = {Popovics-Tóth, Nóra and Bálint, Erika},
	doi = {10.17344/acsi.2022.7648},
	journal-iso = {ACTA CHIM SLOV},
	journal = {ACTA CHIMICA SLOVENICA},
	volume = {69},
	unique-id = {33190219},
	issn = {1318-0207},
	year = {2022},
	eissn = {1580-3155},
	pages = {735-755},
	orcid-numbers = {Bálint, Erika/0000-0002-5107-7089}
}

@article{MTMT:32735801,
	title = {Synthesis of arylphosphinoyl-functionalized dihydroisoquinolines by Reissert‑type reaction and their biological evaluation},
	url = {https://m2.mtmt.hu/api/publication/32735801},
	author = {Popovics-Tóth, Nóra and Meruyert, Turpanova and Németh, Krisztina and Hackler, László and Puskás, László and Bálint, Erika},
	doi = {10.1016/j.tet.2022.132720},
	journal-iso = {TETRAHEDRON},
	journal = {TETRAHEDRON},
	volume = {111},
	unique-id = {32735801},
	issn = {0040-4020},
	year = {2022},
	eissn = {1464-5416},
	orcid-numbers = {Bálint, Erika/0000-0002-5107-7089}
}

@article{MTMT:32640068,
	title = {Biginelli reaction of β-ketophosphonates, aromatic or aliphatic aldehydes and urea derivatives},
	url = {https://m2.mtmt.hu/api/publication/32640068},
	author = {Popovics-Tóth, Nóra and Tajti, Ádám and Bálint, Erika},
	doi = {10.1080/10426507.2021.2011880},
	journal-iso = {PHOSPHOR SULFUR SIL REL ELEM},
	journal = {PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS},
	volume = {197},
	unique-id = {32640068},
	issn = {1042-6507},
	year = {2022},
	eissn = {1563-5325},
	pages = {597-598},
	orcid-numbers = {Bálint, Erika/0000-0002-5107-7089}
}

@article{MTMT:32640048,
	title = {Synthesis of isoindolinone phosphonates and their related derivatives by multicomponent reaction},
	url = {https://m2.mtmt.hu/api/publication/32640048},
	author = {Rávai, Bettina and Popovics-Tóth, Nóra and Tajti, Ádám and Bálint, Erika},
	doi = {10.1080/10426507.2021.2012179},
	journal-iso = {PHOSPHOR SULFUR SIL REL ELEM},
	journal = {PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS},
	volume = {197},
	unique-id = {32640048},
	issn = {1042-6507},
	year = {2022},
	eissn = {1563-5325},
	pages = {599-600},
	orcid-numbers = {Bálint, Erika/0000-0002-5107-7089}
}

@mastersthesis{MTMT:34265664,
	title = {Foszfonát- vagy foszfin-oxid szerkezeti egységet tartalmazó heterociklusos vegyületek előállítása multikomponensű reakciókkal},
	url = {https://m2.mtmt.hu/api/publication/34265664},
	author = {Popovics-Tóth, Nóra},
	publisher = {Budapest University of Technology and Economics},
	unique-id = {34265664},
	year = {2021}
}

@article{MTMT:32538327,
	title = {Microwave-assisted synthesis of benzo[b]phosphole oxide derivatives by oxidative addition of acetylenes and secondary phosphine oxides or alkyl phenyl-H-phosphinates},
	url = {https://m2.mtmt.hu/api/publication/32538327},
	author = {Tajti, Ádám and Kovács, B.D. and Popovics-Tóth, Nóra and Perdih, F. and Bálint, Erika},
	doi = {10.1016/j.tet.2021.132527},
	journal-iso = {TETRAHEDRON},
	journal = {TETRAHEDRON},
	volume = {102},
	unique-id = {32538327},
	issn = {0040-4020},
	year = {2021},
	eissn = {1464-5416},
	orcid-numbers = {Bálint, Erika/0000-0002-5107-7089}
}

@article{MTMT:32465403,
	title = {Study of the Three-Component Reactions of 2-Alkynylbenzaldehydes, Aniline, and Dialkyl Phosphites—The Significance of the Catalyst System},
	url = {https://m2.mtmt.hu/api/publication/32465403},
	author = {Popovics-Tóth, Nóra and Szabó, Kármen and Bálint, Erika},
	doi = {10.3390/ma14206015},
	journal-iso = {MATERIALS},
	journal = {MATERIALS},
	volume = {14},
	unique-id = {32465403},
	abstract = {New, practical approaches for the synthesis of α-amino (2-alkynylphenyl)-methylphosphonates and 1,2-dihydroisoquinolin-1-ylphosphonates were developed. By the propylphosphonic anhydride (T3P®)-mediated Kabachnik–Fields reaction of 2-alkynylbenzaldehydes, aniline, and dialkyl phosphites, α-amino (2-alkynylphenyl)-methylphosphonates were obtained selectively in high yields. The method developed is a simple operation and did not require a chromatographic separation since the products could be isolated from the reaction mixture by a simple extraction. At the same time, 2,3-disubstituted-1,2-dihydroisoquinolin-1-ylphosphonates could be prepared effectively from the same kinds of starting materials (2-alkynylbenzaldehydes, aniline, and dialkyl phosphites) at 60 °C in a short reaction time by changing the catalyst for CuCl. Therefore, it was proved that the catalyst system applied played a crucial role with respect to the reaction outcome.},
	year = {2021},
	eissn = {1996-1944},
	orcid-numbers = {Bálint, Erika/0000-0002-5107-7089}
}