@article{MTMT:34732888,
	title = {A lipidanyagcsere eltéréseinek vizsgálata felnőtt hypertoniás betegek esetén adatbányászati módszerrel},
	url = {https://m2.mtmt.hu/api/publication/34732888},
	author = {Kovács, Beáta and Németh, Ákos and Daróczy, Bálint and Karányi, Zsolt and Maroda, László and Diószegi, Ágnes and Páll, Dénes and Harangi, Mariann},
	doi = {10.33668/hn.28.002},
	journal-iso = {HYPERTONIA NEPHROLOGIA},
	journal = {HYPERTONIA ÉS NEPHROLOGIA},
	volume = {28},
	unique-id = {34732888},
	issn = {1418-477X},
	abstract = {A hypertonia és a hyperlipidaemia együttes előfordulása gyakori, és közös jelenlétük fokozza a cardiovascularis megbetegedések kialakulásának kockázatát. Célul tűztük ki a lipidanyagcsere eltéréseinek vizsgálatát és annak összefüggését a testtömegindexszel (BMI) egy nagyméretű, felnőtt hypertoniás betegpopuláción adatbányászati módszerek alkalmazásával.},
	year = {2024},
	eissn = {2498-6259},
	pages = {13-18}
}

@article{MTMT:34738136,
	title = {INVESTIGATION OF FLOW-MEDIATED DILATATION, CAROTID ARTERY INTIMA- MEDIA THICKNESS AND ARTERIAL STIFFNESS IN SYSTEMIC LUPUS ERYTHEMATOSUS PATIENTS},
	url = {https://m2.mtmt.hu/api/publication/34738136},
	author = {Diószegi, Ágnes and Lőrincz, Hajnalka and Kaali, E. and Harangi, Mariann and Tarr, Tünde},
	journal-iso = {ATHEROSCLEROSIS},
	journal = {ATHEROSCLEROSIS},
	volume = {379},
	unique-id = {34738136},
	issn = {0021-9150},
	year = {2023},
	eissn = {1879-1484},
	pages = {S152-S152}
}

@article{MTMT:34119117,
	title = {Assessment of Hypertensive Patients’ Complex Metabolic Status Using Data Mining Methods},
	url = {https://m2.mtmt.hu/api/publication/34119117},
	author = {Kovács, Beáta and Németh, Ákos and Daróczy, Bálint Zoltán and Karányi, Zsolt and Maroda, László and Diószegi, Ágnes and Harangi, Mariann and Páll, Dénes},
	doi = {10.3390/jcdd10080345},
	journal-iso = {J CARDIOVASC DEV DIS},
	journal = {JOURNAL OF CARDIOVASCULAR DEVELOPMENT AND DISEASE},
	volume = {10},
	unique-id = {34119117},
	issn = {2308-3425},
	abstract = {Cardiovascular diseases are among the leading causes of mortality worldwide. Hypertension is a preventable risk factor leading to major cardiovascular events. We have not found a comprehensive study investigating Central and Eastern European hypertensive patients’ complex metabolic status. Therefore, our goal was to calculate the prevalence of hypertension and associated metabolic abnormalities using data-mining methods in our region. We assessed the data of adults who visited the University of Debrecen Clinical Center’s hospital (n = 937,249). The study encompassed data from a period of 20 years (2001–2021). We detected 292,561 hypertensive patients. The calculated prevalence of hypertension was altogether 32.2%. Markedly higher body mass index values were found in hypertensive patients as compared to non-hypertensives. Significantly higher triglyceride and lower HDL-C levels were found in adults from 18 to 80 years old. Furthermore, significantly higher serum glucose and uric acid levels were measured in hypertensive subjects. Our study confirms that the calculated prevalence of hypertension is akin to international findings and highlights the extensive association of metabolic alterations. These findings emphasize the role of early recognition and immediate treatment of cardiometabolic abnormalities to improve the quality of life and life expectancy of hypertensive patients.},
	year = {2023},
	eissn = {2308-3425},
	pages = {345-359},
	orcid-numbers = {Daróczy, Bálint Zoltán/0000-0001-6233-3490}
}

@article{MTMT:33777179,
	title = {Changes in Clinical Manifestations and Course of Systemic Lupus Erythematosus and Secondary Antiphospholipid Syndrome over Three Decades},
	url = {https://m2.mtmt.hu/api/publication/33777179},
	author = {Nagy, Nikolett and Papp, Gábor and Gáspár-Kiss, Eszter and Diószegi, Ágnes and Tarr, Tünde},
	doi = {10.3390/biomedicines11041218},
	journal-iso = {BIOMEDICINES},
	journal = {BIOMEDICINES},
	volume = {11},
	unique-id = {33777179},
	abstract = {Systemic lupus erythematosus (SLE) is often associated with antiphospholipid syndrome (APS), which potentially results in a more severe disease course and reduced life expectancy. Since the therapeutic guidelines have been refined in the last 15 years, we assumed that the diseases course has become more favorable. In order to shed light on these achievements, we compared the data of SLE patients diagnosed before and since 2004. In our retrospective study, we assessed a wide spectrum of clinical and laboratory data of 554 SLE patients who received regular follow-up care and therapy at our autoimmune center. Among these patients, 247 had antiphospholipid antibodies (APAs) without clinical signs of APS, and 113 had definitive APS. In the APS group, among patients diagnosed since 2004, deep vein thrombosis (p = 0.049) and lupus anticoagulant positivity (p = 0.045) were more frequent, while acute myocardial infarction was less frequent (p = 0.021) compared with patients diagnosed before 2004. Among the APA positive patients without definitive APS, anti-cardiolipin antibody positivity (p = 0.024) and development of chronic renal failure (p = 0.005) decreased in patients diagnosed since 2004. Our study demonstrates that the disease course has changed in recent years; however, in the presence of APS, we have to expect repeated thrombotic events despite adequate anticoagulant therapy.},
	keywords = {Therapy; disease course; systemic lupus erythematosus; ANTIPHOSPHOLIPID SYNDROME},
	year = {2023},
	eissn = {2227-9059},
	pages = {1-10}
}

@article{MTMT:33688871,
	title = {Role of Altered Metabolism of Triglyceride-Rich Lipoprotein Particles in the Development of Vascular Dysfunction in Systemic Lupus Erythematosus},
	url = {https://m2.mtmt.hu/api/publication/33688871},
	author = {Diószegi, Ágnes and Lőrincz, Hajnalka and Kaáli, Eszter and Soltész, Pál and Perge, Bianka and Varga, Éva and Harangi, Mariann and Tarr, Tünde},
	doi = {10.3390/biom13030401},
	journal-iso = {BIOMOLECULES},
	journal = {BIOMOLECULES},
	volume = {13},
	unique-id = {33688871},
	issn = {2218-273X},
	abstract = {Background: Impaired lipid metabolism contributes to accelerated inflammatory responses in addition to promoting the formation of atherosclerosis in systemic lupus erythematosus (SLE). We aimed to evaluate the lipid profile, inflammatory markers, and vascular diagnostic tests in active SLE patients to clarify the association between dyslipidemia and early vascular damage. Patients and Methods: 51 clinically active SLE patients and 41 age- and gender-matched control subjects were enrolled in the study. Lipoprotein subfractions were detected by Lipoprint. Brachial artery flow-mediated dilation and common carotid intima-media thickness were detected by ultrasonography. Arterial stiffness indicated by augmentation index (Aix) and pulse wave velocity was measured by arteriography. Results: We found significantly higher Aix, higher VLDL ratio, plasma triglyceride, ApoB100, and small HDL, as well as lower HDL-C, large HDL, and ApoA1 in patients with SLE. There was a significant positive correlation of Aix with triglyceride, VLDL, IDL-C, IDL-B, and LDL1. A backward stepwise multiple regression analysis showed IDL-C subfraction to be the best predictor of Aix. Conclusions: Our results indicate that in young patients with SLE, triglyceride-rich lipoproteins influence vascular function detected by Aix. These parameters may be assessed and integrated into the management plan for screening cardiovascular risk in patients with SLE.},
	year = {2023},
	eissn = {2218-273X},
	orcid-numbers = {Varga, Éva/0000-0003-2716-0541}
}

@article{MTMT:33586340,
	title = {Determining the prevalence of childhood hypertension and its concomitant metabolic abnormalities using data mining methods in the Northeastern region of Hungary},
	url = {https://m2.mtmt.hu/api/publication/33586340},
	author = {Kovács, Beáta and Németh, Ákos and Daróczy, Bálint Zoltán and Karányi, Zsolt and Maroda, László and Diószegi, Ágnes and Nádró, Bíborka and Szabó, Tamás and Harangi, Mariann and Páll, Dénes},
	doi = {10.3389/fcvm.2022.1081986},
	journal-iso = {FRONT CARDIOVASC MED},
	journal = {FRONTIERS IN CARDIOVASCULAR MEDICINE},
	volume = {9},
	unique-id = {33586340},
	issn = {2297-055X},
	year = {2023},
	eissn = {2297-055X},
	orcid-numbers = {Daróczy, Bálint Zoltán/0000-0001-6233-3490}
}

@article{MTMT:32841064,
	title = {The Importance of Arterial Stiffness Assessment in Patients with Familial Hypercholesterolemia},
	url = {https://m2.mtmt.hu/api/publication/32841064},
	author = {Kovács, Beáta and Cseprekál, Orsolya and Diószegi, Ágnes and Lengyel, Szabolcs and Maroda, László and Paragh, György and Harangi, Mariann and Páll, Dénes},
	doi = {10.3390/jcm11102872},
	journal-iso = {J CLIN MED},
	journal = {JOURNAL OF CLINICAL MEDICINE},
	volume = {11},
	unique-id = {32841064},
	year = {2022},
	eissn = {2077-0383},
	orcid-numbers = {Cseprekál, Orsolya/0000-0003-2867-3875}
}

@article{MTMT:32815159,
	title = {Gyógyszeres terápiás lehetőségek az elhízás kezelésében},
	url = {https://m2.mtmt.hu/api/publication/32815159},
	author = {Diószegi, Ágnes and Harangi, Mariann},
	journal-iso = {GYÓGYSZERÉSZ TOVÁBBKÉPZÉS},
	journal = {GYÓGYSZERÉSZ TOVÁBBKÉPZÉS},
	volume = {16},
	unique-id = {32815159},
	issn = {1788-9049},
	abstract = {Az elhízás a társuló szövődmények kialakulása miatt egyre nagyobb terhet ró az egészségügyi ellátórendszerre hazánkban és világszerte egyaránt. Elsődleges fontosságú a megelőzés, mert a már kialakult túlsúly és elhízás kezelése nagy kihívást jelent a beteg és a kezelőorvos számára. A kezelés alapját az életmód terápia képezi, mely a fizikai aktivitás fokozását és a diétát foglalja magába, de ennek nem megfelelő hatékonysága esetén gyógyszeres kezelés, vagy műtéti megoldás is szükségessé válhat. A gyógyszeres kezelés lehetősége az évtizedek óta zajló intenzív kutatások ellenére néhány gyógyszercsoportra korlátozódik. Az utóbbi években azonban a korábban 2-es típusú cukorbetegeknél alkalmazott glucagon-like-peptide-1 (GLP-1) analógok közül a semaglutid és a liraglutid adását is engedélyezték cukorbetegségben nem szenvedő elhízott betegekben súlycsökkentő kezelésként. Ezek a szerek több támadásponton fejtik ki hatásukat, csökkentik az étvágyérzetet és lassítják a gyomorürülést, emellett számos kedvező anyagcsere hatással rendelkeznek. A korábbi klinikai vizsgálatok és a mindennapi tapasztalat is alátámasztja a hatékony súlycsökkentő hatásukat és kedvező mellékhatás profiljukat, mely miatt ezek a szerek az elhízás gyógyszeres kezelésének legfontosabb eszközévé váltak.},
	keywords = {elhízás; Liraglutid; GLP-1-analógok; semaglutid},
	year = {2022},
	pages = {48-51}
}

@article{MTMT:32500654,
	title = {STRONG CORRELATIONS BETWEEN SERUM FIBROBLAST GROWTH FACTOR 21 LEVEL AND LIPID PARAMETERS IN PATIENTS WITH AUTOIMMUNE THYROIDITIS},
	url = {https://m2.mtmt.hu/api/publication/32500654},
	author = {Berta, Eszter and Bodor, Miklós and Halmi, S. and Lengyel, I. and Diószegi, Ágnes and Katkó, Mónika and Seres, Ildikó and Nagy, Endre and Paragh, György and Harangi, Mariann},
	doi = {10.1016/j.atherosclerosis.2021.06.616},
	journal-iso = {ATHEROSCLEROSIS},
	journal = {ATHEROSCLEROSIS},
	volume = {331},
	unique-id = {32500654},
	issn = {0021-9150},
	year = {2021},
	eissn = {1879-1484},
	pages = {E201-E201}
}

@article{MTMT:31993926,
	title = {A rheopheresiskezeléssel szerzett első hazai tapasztalatok = The first local experiences with rheopheresis treatment},
	url = {https://m2.mtmt.hu/api/publication/31993926},
	author = {Soltész, Pál and Németh, Norbert and Gál, Kristóf and Nánásy-Vass, Melinda and Diószegi, Ágnes and Mechler, Ferenc and Fekete, Klára and Somogyi, Viktória and Módis, László},
	doi = {10.1556/650.2021.31889},
	journal-iso = {ORV HETIL},
	journal = {ORVOSI HETILAP},
	volume = {162},
	unique-id = {31993926},
	issn = {0030-6002},
	year = {2021},
	eissn = {1788-6120},
	pages = {375-382},
	orcid-numbers = {Németh, Norbert/0000-0002-1162-3778}
}