@article{MTMT:32167983,
	title = {Activity of the Lateral Hypothalamus during Genetically Determined Absence Seizures},
	url = {https://m2.mtmt.hu/api/publication/32167983},
	author = {Sere, Péter and Nikolett, Zsigri and Raffai, Tímea and Furdan, Szabina and Győri, Fanni and Vincenzo, Crunelli and Lőrincz, László Magor},
	doi = {10.3390/ijms22179466},
	journal-iso = {INT J MOL SCI},
	journal = {INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES},
	volume = {22},
	unique-id = {32167983},
	issn = {1661-6596},
	year = {2021},
	eissn = {1422-0067}
}

@article{MTMT:32037613,
	title = {Systemic administration of ivabradine, a hyperpolarization-activated cyclic nucleotide-gated channel inhibitor, blocks spontaneous absence seizures},
	url = {https://m2.mtmt.hu/api/publication/32037613},
	author = {Iacone, Yasmine and Morais, Tatiana P. and David, Francois and Delicata, Francis and Sandle, Joanna and Raffai, Tímea and Parri, Harri Rheinallt and Weisser, Johan Juhl and Bundgaard, Christoffer and Klewe, Ib Vestergaard and Tamás, Gábor and Thomsen, Morten Skott and Crunelli, Vincenzo and Lőrincz, László Magor},
	doi = {10.1111/epi.16926},
	journal-iso = {EPILEPSIA},
	journal = {EPILEPSIA},
	volume = {62},
	unique-id = {32037613},
	issn = {0013-9580},
	abstract = {Objective Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels are known to be involved in the generation of absence seizures (ASs), and there is evidence that cortical and thalamic HCN channel dysfunctions may have a proabsence role. Many HCN channel blockers are available, but their role in ASs has been investigated only by localized brain injection or in in vitro model systems due to their limited brain availability. Here, we investigated the effect on ASs of orally administered ivabradine (an HCN channel blocker approved for the treatment of heart failure in humans) following injection of the P-glycoprotein inhibitor elacridar, which is known to increase penetration into the brain of drug substrates for this efflux transporter. The action of ivabradine was also tested following in vivo microinjection into the cortical initiation network (CIN) of the somatosensory cortex and in the thalamic ventrobasal nucleus (VB) as well as on cortical and thalamocortical neurons in brain slices. Methods We used electroencephalographic recordings in freely moving Genetic Absence Epilepsy Rats From Strasbourg (GAERSs) to assess the action of oral administration of ivabradine, with and without elacridar, on ASs. Ivabradine was also microinjected into the CIN and VB of GAERSs in vivo and applied to Wistar CIN and GAERS VB slices while recording patch-clamped cortical Layer 5/6 and thalamocortical neurons, respectively. Results Oral administration of ivabradine markedly and dose-dependently reduced ASs. Ivabradine injection into CIN abolished ASs and elicited small-amplitude 4-7-Hz waves (without spikes), whereas in the VB it was less potent. Moreover, ivabradine applied to GAERS VB and Wistar CIN slices selectively decreased HCN channel-dependent properties of cortical Layer 5/6 pyramidal and thalamocortical neurons, respectively. Significance These results provide the first demonstration of the antiabsence action of a systemically administered HCN channel blocker, indicating the potential of this class of drugs as a novel therapeutic avenue for ASs.},
	keywords = {MODEL; CORTEX; EPILEPSY; valproic acid; childhood; Pacemaker; anticonvulsant; THALAMOCORTICAL NEURONS; CHILDHOOD ABSENCE EPILEPSY; NETWORK MECHANISMS; rat; I-h current; OPERATIONAL CLASSIFICATION},
	year = {2021},
	eissn = {1528-1167},
	pages = {1729-1743},
	orcid-numbers = {Delicata, Francis/0000-0002-5339-5275; Tamás, Gábor/0000-0002-7905-6001}
}

@{MTMT:31647881,
	title = {Poststerone increases muscle fibre size partly similar to its metabolically parent compound, 20-hydroxyecdysone},
	url = {https://m2.mtmt.hu/api/publication/31647881},
	author = {Csábi, József and Raffai, Tímea and Hunyadi, Attila and Zádor, Ernő},
	booktitle = {Proceedings of the EFOP-3.6.2-16-2017-00006 (LIVE LONGER) project},
	unique-id = {31647881},
	year = {2020},
	pages = {93},
	orcid-numbers = {Hunyadi, Attila/0000-0003-0074-3472; Zádor, Ernő/0000-0003-3029-6845}
}

@mastersthesis{MTMT:31390118,
	title = {Influence of chemical compounds and cellautonomous immunity on the replication of sexually transmitted pathogens [Különböző kémiai vegyületek és a sejt-autonóm immunitás hatásai a szexuálisan terjedő kórokozók szaporodására]},
	url = {https://m2.mtmt.hu/api/publication/31390118},
	author = {Raffai, Tímea},
	doi = {10.14232/phd.10379},
	publisher = {SZTE},
	unique-id = {31390118},
	year = {2020}
}

@article{MTMT:31156856,
	title = {Correlation between detergent activity and anti-herpes simplex virus-2 activity of commercially available vaginal gels},
	url = {https://m2.mtmt.hu/api/publication/31156856},
	author = {Párduczné Szöllősi, Andrea and Raffai, Tímea and Bogdanov, Anita and Endrész, Valéria and Párducz, László and Somogyvári, Ferenc and Janovák, László and Burián, Katalin and Virók, Dezső},
	doi = {10.1186/s13104-020-4918-4},
	journal-iso = {BMC RES NOTES},
	journal = {BMC RESEARCH NOTES},
	volume = {13},
	unique-id = {31156856},
	issn = {1756-0500},
	year = {2020},
	orcid-numbers = {Bogdanov, Anita/0000-0003-3067-8835; Endrész, Valéria/0000-0002-9402-3857; Janovák, László/0000-0002-2066-319X; Burián, Katalin/0000-0003-1300-2374}
}

@article{MTMT:30810007,
	title = {Azithromycin-liposomes as a novel approach for localized therapy of cervicovaginal bacterial infections},
	url = {https://m2.mtmt.hu/api/publication/30810007},
	author = {Vanic, Zeljka and Rukavina, Zora and Manner, Suvi and Fallarero, Adyary and Uzelac, Lidija and Kralj, Marijeta and Klaric, Daniela Amidzic and Bogdanov, Anita and Raffai, Tímea and Virók, Dezső and Filipovic-Grcic, Jelena and Skalko-Basnet, Natasa},
	doi = {10.2147/IJN.S211691},
	journal-iso = {INT J NANOMED},
	journal = {INTERNATIONAL JOURNAL OF NANOMEDICINE},
	volume = {14},
	unique-id = {30810007},
	issn = {1176-9114},
	abstract = {Background: Efficient localized cervicovaginal antibacterial therapy, enabling the delivery of antibiotic to the site of action at lower doses while escaping systemic drug effects and reducing the risk of developing microbial resistance, is attracting considerable attention. Liposomes have been shown to allow sustained drug release into vaginal mucosa and improve delivery of antibiotics to bacterial cells and biofilms Azithromycin (AZI), a potent broad-spectrum macrolide antibiotic, has not yet been investigated for localized therapy of cervicovaginal infections, although it is administered orally for the treatment of sexually transmitted diseases. Encapsulation of AZI in liposomes could improve its solubility, antibacterial activity, and allow the prolonged drug release in the cervicovaginal tissue, while avoiding systemic side effects.Purpose: The objective of this study was to develop AZI-liposomes and explore their potentials for treating cervicovaginal infections.Methods: AZI-liposomes that differed in bilayer elasticity/rigidity and surface charge were prepared and evaluated under simulated cervicovaginal conditions to yield optimized liposomes, which were assessed for antibacterial activity against several planktonic and biofilm-forming Escherichia coli strains and intracellular Chlamydia trachomatis, ex vivo AZI vaginal deposition/penetration, and in vitro cytotoxicity toward cervical cells.Results: Negatively charged liposomes with rigid bilayers (CL-3), propylene glycol liposomes (PGL-2) and deformable propylene glycol liposomes (DPGL-2) were efficient against planktonic E. coli ATCC 700928 and K-12. CL-3 was superior for preventing the formation of E. coli ATCC 700928 and K-12 biofilms, with IC50 values (concentrations that inhibit biofilm viability by 50%) up to 8-fold lower than those of the control (free AZI). DPGL-2 was the most promising for eradication of already formed E. coli biofilms and for treating C. trachomatis infections. All AZI-liposomes were biocompatible with cervical cells and improved localization of the drug inside vaginal tissue compared with the control.Conclusion: The performed studies confirm the potentials of AZI-liposomes for localized cervicovaginal therapy.},
	keywords = {Escherichia coli; Biofilm; biocompatibility; Chlamydia trachomatis; vaginal drug delivery; cervical cells},
	year = {2019},
	eissn = {1178-2013},
	pages = {5957-5976},
	orcid-numbers = {Bogdanov, Anita/0000-0003-3067-8835}
}

@{MTMT:30807840,
	title = {Antimicrobial Resistance Screening in Chlamydia trachomatis by Optimized McCoy Cell Culture System and Direct qPCR-Based Monitoring of Chlamydial Growth},
	url = {https://m2.mtmt.hu/api/publication/30807840},
	author = {Meštrović, Tomislav and Virók, Dezső and Ljubin-Sternak, Sunčanica and Raffai, Tímea and Burián, Katalin and Vraneš, Jasmina},
	booktitle = {Chlamydia trachomatis},
	doi = {10.1007/978-1-4939-9694-0_5},
	unique-id = {30807840},
	year = {2019},
	pages = {33-43},
	orcid-numbers = {Burián, Katalin/0000-0003-1300-2374}
}

@article{MTMT:30773411,
	title = {Poststerone increases muscle fibre size partly similar to its metabolically parent compound, 20-hydroxyecdysone},
	url = {https://m2.mtmt.hu/api/publication/30773411},
	author = {Csábi, József and Raffai, Tímea and Hunyadi, Attila and Zádor, Ernő},
	doi = {10.1016/j.fitote.2019.03.017},
	journal-iso = {FITOTERAPIA},
	journal = {FITOTERAPIA},
	volume = {134},
	unique-id = {30773411},
	issn = {0367-326X},
	year = {2019},
	eissn = {1873-6971},
	pages = {459-464},
	orcid-numbers = {Hunyadi, Attila/0000-0003-0074-3472; Zádor, Ernő/0000-0003-3029-6845}
}

@article{MTMT:30735137,
	title = {Indoleamine 2,3-Dioxygenase Activity in Chlamydia muridarum and Chlamydia pneumoniae Infected Mouse Lung Tissues},
	url = {https://m2.mtmt.hu/api/publication/30735137},
	author = {Virók, Dezső and Raffai, Tímea and Kókai, Dávid and Paróczai, Dóra and Bogdanov, Anita and Veres, Gábor and Vécsei, László and Póliska, Szilárd and Tiszlavicz, László and Somogyvári, Ferenc and Endrész, Valéria and Burián, Katalin},
	doi = {10.3389/fcimb.2019.00192},
	journal-iso = {FRONT CELL INFECT MI},
	journal = {FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY},
	volume = {9},
	unique-id = {30735137},
	issn = {2235-2988},
	year = {2019},
	eissn = {2235-2988},
	orcid-numbers = {Bogdanov, Anita/0000-0003-3067-8835; Vécsei, László/0000-0001-8037-3672; Tiszlavicz, László/0000-0003-1134-6587; Endrész, Valéria/0000-0002-9402-3857; Burián, Katalin/0000-0003-1300-2374}
}

@article{MTMT:30637094,
	title = {Kereskedelmi forgalomban levő hüvelyi gélek herpesz szimplex vírus-2 ellenes hatásának vizsgálata},
	url = {https://m2.mtmt.hu/api/publication/30637094},
	author = {Párduczné Szöllősi, Andrea and Párducz, László and Raffai, Tímea and Virók, Dezső},
	journal-iso = {ORVOSTUDOMÁNYI ÉRTESÍTŐ},
	journal = {BULLETIN OF MEDICAL SCIENCES / ORVOSTUDOMÁNYI ÉRTESÍTŐ},
	volume = {92},
	unique-id = {30637094},
	issn = {1453-0953},
	year = {2019},
	eissn = {2537-5059},
	pages = {38-39}
}