TY - JOUR AU - Bencze, Bulcsú AU - Golzio Navarro Cavalcante, Bianca AU - Romandini, Mario AU - Barabás-Róna, Virág AU - Váncsa, Szilárd AU - Varga, Gábor AU - Kivovics, Márton AU - Szabó, Bence AU - Agócs, Gergely AU - Géczi, Zoltán AU - Hermann, Péter AU - Hegyi, Péter AU - Végh, Dániel TI - Prediabetes and Poorly Controlled Type-2 Diabetes as Risk Indicators for Peri-implant Diseases:A Systematic Review and Meta-analysis JF - JOURNAL OF DENTISTRY J2 - J DENTISTRY PY - 2024 SN - 0300-5712 DO - 10.1016/j.jdent.2024.105094 UR - https://m2.mtmt.hu/api/publication/34871745 ID - 34871745 AB - ABSTRACT Objective The study answers the PECO question: “In adults with dental implants (P), do subjects suffering from type-2 diabetes or prediabetes (E) have worse peri-implant conditions (O) than subjects without type-2 diabetes and prediabetes (C)?”. Prediabetes (5.7-6.4% HbA1c), and the different qualities of glycemic control in type-2 diabetes; well-controlled (>8% HbA1c), and poorly controlled (>8% HbA1c) individuals; were classified according to the recommendations of the American Diabetes Association. Data Predefined search keys were used with search terms including: Dental implant, diabetes mellitus, glycemic control and HbA1c. Sources An electronic search in the MEDLINE, Embase, and Cochrane libraries were conducted without any filters or language restrictions. Additionally, manual search of the reference lists were carried out to identify all relevant articles. Study Selection Eligibility criteria were cohort, case-control and cross-sectional studies that answerd our PECO question with at least 1 year of follow-up. From a total of 2660 records, 35 articles (1761 individuals) were included in the analysis. Meta-analytic difference in means for crestal bone loss was 1.2 mm [95% CI=0.4; 2.1] in patients with prediabetes, 1.8 mm [CI=1.0; 2.7] in poorly controlled patients, whereas 0.4 mm [CI=-0.3; 1.1] in well-controlled individuals. Meta-regression showed that 1% increase in HbA1c increased crestal bone loss by 0.24 mm. Conclusions Within the limitations of the study, patients with poorly controlled type-2 diabetes or prediabetes may have worse peri-implant conditions compared to patients without diabetes and well-controlled type-2 diabetes. Well-controlled type-2 diabetes is not a risk indicator for peri-implant diseases. Clinical Significance Clinicians should measure blood HbA1c levels when planning implant-supported restorations, thus patients with undiagnosed or poorly controlled type-2 diabetes can be identified, that allows for glycemic level adjustment by the diabetologist specialist prior to dental implant surgery, ensuring peri-implant health. Protocol registration number (CRD42022375263) LA - English DB - MTMT ER - TY - JOUR AU - Magyar, Donát AU - Tischner, Zsófia AU - Szabó, Bence AU - Freiler-Nagy, Ágnes AU - Papp, Tamás AU - Allaga, Henrietta AU - Kredics, László TI - Characterization of Indoor Molds after Ajka Red Mud Spill, Hungary JF - PATHOGENS J2 - PATHOGENS VL - 13 PY - 2024 IS - 1 PG - 15 SN - 2076-0817 DO - 10.3390/pathogens13010022 UR - https://m2.mtmt.hu/api/publication/34451185 ID - 34451185 AB - A red mud suspension of ~700,000 m3 was accidentally released from the alumina plant in Ajka, Hungary, on the 4th of October 2010, flooding several buildings in the nearby towns. As there is no information in the literature on the effects of red mud on indoor mold growth, we conducted studies to answer the following question: does the heavy metal content of red mud inhibit fungal colonization in flooded houses? In order to gain knowledge on fungal spectra colonizing surfaces soaked with red mud and on the ability of fungi to grow on them, swabs, tape lifts, and air samples were collected from three case study buildings. A total of 43 fungal taxa were detected. The dominant species were Penicillium spp. on plaster/brick walls, but Aspergillus series Versicolores, Cladosporium, Acremonium, and Scopulariopsis spp. were also present. The level of airborne penicillia was high in all indoor samples. Selected fungal strains were subcultured on 2% MEA with 10−1 and 10−4 dilutions of red mud. The growth rate of most of the strains was not significantly reduced by red mud on the artificial media. The consequences of similar industrial flooding on indoor molds are also discussed in this paper. LA - English DB - MTMT ER - TY - JOUR AU - Golzio Navarro Cavalcante, Bianca AU - Schulze Wenning, Alexander AU - Szabó, Bence AU - Czumbel, László Márk AU - Hegyi, Péter AU - Borbély, Judit AU - Németh, Orsolya AU - Bartha, Károly AU - Gerber, Gábor AU - Varga, Gábor TI - Combined Casein Phosphopeptide-Amorphous Calcium Phosphate and Fluoride Is Not Superior to Fluoride Alone in Early Carious Lesions : A Meta-Analysis JF - CARIES RESEARCH J2 - CARIES RES VL - 58 PY - 2024 IS - 1 SP - 1 EP - 16 PG - 16 SN - 0008-6568 DO - 10.1159/000533547 UR - https://m2.mtmt.hu/api/publication/34223828 ID - 34223828 N1 - * Megosztott szerzőség AB - There is a growing need for effective methods in the management of early-stage carious lesions. Therefore, the aim of this study was to evaluate the effect of combined casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) and fluoride on white spot lesions (WSLs) compared to fluoride-only interventions. This meta-analysis was performed according to PRISMA guidelines and registered in PROSPERO (CRD42021286245). The Medline, EMBASE and Cochrane Central databases were searched until October 17, 2022. Eligible studies were randomized controlled trials (RCTs). Outcome variables included Laser Fluorescence (LF), Quantitative Light-Induced Fluorescence (QLF), and lesion area scores. The random-effects model was used for analysis, and results were given as standardized mean difference (SMD) and mean difference (MD) with a 95% Confidence Interval. Risk of Bias was assessed using the RoB 2 tool, and the level of evidence with GRADE. Our systematic search yielded 973 records after duplicate removal, 21 studies were included for qualitative synthesis, and 15 studies were eligible for quantitative analysis. No significant difference was found between CPP-ACP and fluoride versus fluoride alone in LF at 1, 3 and 6 months of use: SMD -0.30 (-0.64; 0.04); SMD -0.47 (-1.02; 0.07); SMD -0.49 (-1.13; 0.15), respectively. For QLF, the analysis did not demonstrate significant differences between these two kinds of treatment at one and six months of use: MD 0.21 (-0.30;0.71); MD 0.60 (-1.70;2.90), but at three months higher QLF values were found in the fluoride-only group compared to the CPP-ACP and fluoride combination was shown regarding the WSLs: MD 0.58 (0.25;0.91). On the contrary, data showed a small but statistically significant decrease in the lesion area in favor of the CPP-ACP plus fluoride vs fluoride alone at six months MD -0.38 (-0.72; -0.04). None of these observed changes indicated substantial clinical relevance. The combination of CPP-ACP and fluoride did not overcome the effect of fluoride given alone. Our data suggest that fluoride itself is effective in improving WSLs. However, the certainty of evidence was very low. These results indicate that further studies and future development of more effective than CPP-ACP are needed in addition to fluoride to achieve robust amelioration of WSLs. LA - English DB - MTMT ER - TY - JOUR AU - Kelemen, Kata AU - Kőnig, János AU - Czumbel, László Márk AU - Szabó, Bence AU - Hegyi, Péter AU - Gerber, Gábor AU - Borbély, Judit AU - Mikulás, Krisztina Ágnes AU - Schmidt, Péter AU - Hermann, Péter TI - Additional splint therapy has no superiority in myogenic temporomandibular disorders : A systematic review and meta-analysis of randomized controlled trials JF - JOURNAL OF PROSTHODONTIC RESEARCH J2 - J PROSTHODONT RES VL - 68 PY - 2024 IS - 1 SP - 12 EP - 19 PG - 8 SN - 1883-1958 DO - 10.2186/jpr.JPR_D_22_00264 UR - https://m2.mtmt.hu/api/publication/34008198 ID - 34008198 N1 - Meta-Analysis; Systematic Review; Journal Article AB - Temporomandibular disorders (TMDs) are frequent stomatological disorders. However, their treatment is controversial. Therefore, we compared the efficacy of combination therapy (splint therapy along with physiotherapy, manual therapy, and counseling) with physiotherapy, manual therapy, and counseling alone. The extent of mouth opening and pain perception were the outcomes.Systematic searches for English publications were performed using four major literature databases (Cochrane Library, EMBASE, PubMed, and Web of Science). We included randomized controlled trials. We calculated mean differences with 95% confidence interval (CI) for pain perception and maximum mouth opening (MMO) for the two groups. The Hartung-Knapp adjustment was used for cases comprising at least five studies.Six articles were included in the pain perception category, and four were reviewed for MMO at baseline. Four articles assessed pain perception, and two assessed MMO at 1 month. Five articles were analyzed upon comparing pain perception at baseline and 1-month follow-up. The mean difference was -2.54 [95% CI: -3.38; to -1.70] in the intervention group and -2.33 [95% CI: -4.06; to -0.61] in the control group. Two articles were analyzed upon comparing MMO at baseline and 1-month follow-up. The mean difference in the intervention group was 3.69 [95% CI: -0.34; 7.72], whereas that in the control group was 3.62 [95% CI: -3.43; 10.67].Both therapies can be used in the management of myogenic TMD. Due to the marginal differences between the baseline and 1-month values, our results could not confirm the efficacy of combination therapy. LA - English DB - MTMT ER - TY - JOUR AU - Kőnig, János AU - Kelemen, Kata AU - Czumbel, László Márk AU - Szabó, Bence AU - Varga, Gábor AU - Borbély, Judit AU - Németh, Orsolya AU - Hegyi, Péter AU - Hermann, Péter TI - Current status of optical scanning in facial prosthetics : A systematic review and meta-analysis JF - JOURNAL OF PROSTHODONTIC RESEARCH J2 - J PROSTHODONT RES VL - 68 PY - 2024 IS - 1 SP - 1 EP - 11 PG - 11 SN - 1883-1958 DO - 10.2186/jpr.JPR_D_22_00221 UR - https://m2.mtmt.hu/api/publication/34008188 ID - 34008188 N1 - Meta-Analysis; Systematic Review; Journal Article AB - To assess the accuracy of scanning technologies for constructing facial prostheses on human faces.Our systematic search was performed on five databases. Studies reporting on human volunteers (P) whose faces were scanned with a scanning technology were eligible. The anthropometrical interlandmark distances (ILDs) were used as indicators of accuracy; the ILDs are measured on the virtual models (I) and directly on the faces (C). The virtual models deviated from their true values (O). Studies reporting the measurements on patients with or without facial deformities were included, but cadavers or inanimate objects were reasons for exclusion. We performed a mean difference (MD) / standardized MD analysis with a random effect model. The difficulties regarding the scanning procedure mentioned in the articles were also assessed.We found 3723 records after duplicate removal. Twenty five articles were eligible for the qualitative review, and ten articles were included in the quantitative synthesis. Eight different ILDs were compared in MD analyses. The differences were between -0.54-0.43 mm. We also performed a regional three-dimensional analysis to compare scanning technologies in each major region. No significant differences were found in any of the regions and axes. The most mentioned difficulties were artifacts due to motion or blinking.The results suggest no systematic skew in linear dimensions neither between direct caliper measurements nor between measurements on the scanned models, scanning technologies, or facial regions. LA - English DB - MTMT ER - TY - JOUR AU - Kőnig, János AU - Kelemen, Kata AU - Váncsa, Szilárd AU - Szabó, Bence AU - Varga, Gábor AU - Mikulás, Krisztina Ágnes AU - Borbély, Judit AU - Hegyi, Péter AU - Hermann, Péter TI - Comparative analysis of surgical and prosthetic rehabilitation in maxillectomy : A systematic review and meta-analysis on quality-of-life scores and objective speech and masticatory measurements JF - JOURNAL OF PROSTHETIC DENTISTRY J2 - J PROSTHET DENT PY - 2023 SN - 0022-3913 DO - 10.1016/j.prosdent.2023.11.023 UR - https://m2.mtmt.hu/api/publication/34453576 ID - 34453576 N1 - Assistant Lecturer, Department of Prosthodontics, Semmelweis University, Budapest, Hungary; and PhD student, Centre for Translational Medicine, Semmelweis University, Budapest, Hungary, Hungary Scientific Methodological Expert, Centre for Translational Medicine, Semmelweis University, Budapest, Hungary Biostatistician, Centre for Translational Medicine, Semmelweis University, Budapest, Hungary General & Operative Vice Director, Centre for Translational Medicine, Semmelweis University, Budapest, Hungary; Full Professor, Department of Oral Biology, Semmelweis University, Budapest, Hungary; and Supervisor, Centre for Translational Medicine, Semmelweis University, Budapest, Hungary, Hungary Assistant Professor, Department of Prosthodontics, Semmelweis University, Budapest, Hungary; and Supervisor, Centre for Translational Medicine, Semmelweis University, Budapest, Hungary, Hungary Associate Professor, Department of Prosthodontics, Semmelweis University, Budapest, Hungary; and Supervisor, Centre for Translational Medicine, Semmelweis University, Budapest, Hungary, Hungary Strategic Director, Centre for Translational Medicine, Semmelweis University, Budapest, Hungary; and Strategic Director, Institute for Translational Medicine, Medical School, University of Pécs, Pécs, Hungary, Hungary Director and Full Professor, Department of Prosthodontics, Semmelweis University, Budapest, Hungary; and Supervisor, Centre for Translational Medicine, Semmelweis University, Budapest, Hungary, Hungary Export Date: 19 January 2024 CODEN: JPDEA Correspondence Address: Hermann, P.; Department of Prosthodontics, Szentkirályi utca 47, Hungary; email: hermann.peter@semmelweis.hu AB - Patients with oro-antral communication, whether from trauma, disease, or congenital anomalies, have options for surgical reconstruction or prosthetic obturation, but guiding interdisciplinary protocols are lacking.The purpose of this systematic review and meta-analysis was to compare surgical reconstruction and prosthetic obturation, identifying correlations with baseline characteristics to determine the most effective approach for specific patients.A systematic search was conducted in 4 databases. Searching, screening, data extraction, and risk of bias assessment were performed by 2 reviewers. Eligible studies focused on patients with palatomaxillary defects from cancer-related maxilla surgeries. Traumatic or congenital defects were excluded. The study compared prosthetic restoration (either with surgical or definitive obturators) to surgical reconstruction using flaps or grafts. Patients with surgical restoration after tooth extraction were excluded. Both subjective and objective outcomes were used for comparison.Thirteen articles were included in the qualitative synthesis and 9 in the meta-analysis. Patient scores on quality-of-life questionnaires, objective speech, and masticatory ability evaluations were compared. The number of patients who underwent surgical reconstruction was 206, whereas 260 patients received prosthetic obturators. Results showed no significant differences. In the "activity" domain of the University of Washington QoL questionnaire, however, the 1.92 (0.45, 3.40) score difference was not clinically relevant. However, the heterogeneity of trials, the transient nature of subjective evaluations, the low number of participants, and major confounding biases did not allow a solid conclusion to be drawn.The growing number of maxillectomy patients demands firm evidence on which rehabilitation to choose and when it should be done. The result suggests that obturator devices and surgical reconstruction have similar effects on quality of life and health outcomes. A multicentric registry in which patient strata could be analyzed separately by age, adjuvant therapies, defect sizes, and remaining dentition is advocated. LA - English DB - MTMT ER - TY - JOUR AU - Takács, Anna AU - Hardi, Eszter AU - Golzio Navarro Cavalcante, Bianca AU - Szabó, Bence AU - Kispélyi, Ida Barbara AU - Joób-Fancsaly, Árpád AU - Mikulás, Krisztina Ágnes AU - Varga, Gábor AU - Hegyi, Péter AU - Kivovics, Márton TI - Advancing Accuracy in Guided Implant Placement : A Comprehensive Meta-Analysis: Meta-Analysis evaluation of the accuracy of available implant placement Methods JF - JOURNAL OF DENTISTRY J2 - J DENTISTRY VL - 139 PY - 2023 PG - 13 SN - 0300-5712 DO - 10.1016/j.jdent.2023.104748 UR - https://m2.mtmt.hu/api/publication/34216021 ID - 34216021 N1 - Department of Community Dentistry, Semmelweis University, Szentkirályi utca 40, Budapest, 1088, Hungary Centre for Translational Medicine, Semmelweis University, Üllői út 26, Budapest, 1085, Hungary Department of Oro-Maxillofacial Surgery and Stomatology, Semmelweis University, Mária utca 52, Budapest, 1085, Hungary Department of Oral Biology, Semmelweis University, Nagyvárad tér 4, Budapest, 1089, Hungary Department of Prosthodontics, Semmelweis University, Szentkirályi utca 47, Budapest, 1088, Hungary Institute for Translational Medicine, Szentágothai Research Centre, Medical School, University of Pécs, Szigeti út 12, Pécs, 7624, Hungary Division of Pancreatic Diseases, Heart and Vascular Center, Semmelweis University, Városmajor utca 68, Budapest, 1122, Hungary Export Date: 11 January 2024 CODEN: JDENA Correspondence Address: Kivovics, M.Szentkirályi utca 40, Hungary; email: kivovics.marton@dent.semmelweis-univ.hu AB - This meta-analysis aimed to determine the accuracy of currently available computer-assisted implant surgery (CAIS) modalities under in vitro conditions and investigate whether these novel techniques can achieve clinically acceptable accuracy.In vitro studies comparing the postoperative implant position with the preoperative plan were included. Risk of bias was assessed using the Quality Assessment Tool For In Vitro Studies (QUIN Tool) and a sensitivity analysis was conducted using funnel plots.A systematic search was performed on April 18, 2023, using the following three databases: MEDLINE (via PubMed), EMBASE, and Cochrane Central Register of Controlled Trials. No filters or restrictions were applied during the search.A total of 5,894 studies were included following study selection. Robotic- and static CAIS (sCAIS) had the most accurate and clinically acceptable outcomes. sCAIS was further divided according to the guidance level. Among the sCAIS groups, fully guided implant placement had the greatest accuracy. Augmented reality-based CAIS (AR-based CAIS) had clinically acceptable results for all the outcomes except for apical global deviation. Dynamic CAIS (dCAIS) demonstrated clinically safe results, except for horizontal apical deviation. Freehand implant placement was associated with the greatest number of errors.Fully guided sCAIS demonstrated the most predictable outcomes, whereas freehand sCAIS demonstrated the lowest accuracy. AR-based and robotic CAIS may be promising alternatives.To our knowledge, this is the first meta-analysis to evaluate the accuracy of robotic CAIS and investigate the accuracy of various CAIS modalities. LA - English DB - MTMT ER - TY - JOUR AU - Vitai, Viktória AU - Németh, Anna AU - Sólyom, Eleonóra AU - Czumbel, László Márk AU - Szabó, Bence AU - Fazekas, Réka AU - Gerber, Gábor AU - Hegyi, Péter AU - Hermann, Péter AU - Borbély, Judit TI - Evaluation of the accuracy of intraoral scanners for complete-arch scanning : A systematic review and network meta-analysis JF - JOURNAL OF DENTISTRY J2 - J DENTISTRY VL - 137 PY - 2023 PG - 12 SN - 0300-5712 DO - 10.1016/j.jdent.2023.104636 UR - https://m2.mtmt.hu/api/publication/34081440 ID - 34081440 N1 - Centre for Translational Medicine, Semmelweis University, Budapest, Hungary Department of Prosthodontics, Semmelweis University, Budapest, Hungary Department of Periodontology, Semmelweis University, Budapest, Hungary Department of Restorative Dentistry and Endodontics, Semmelweis University, Budapest, Hungary Section of Oral Morphology, Department of Anatomy Histology and Embryology, Semmelweis University, Budapest, Hungary Division of Pancreatic Diseases, Heart and Vascular Center, Semmelweis University, Budapest, Hungary Institute for Translational Medicine, Medical School, University of Pécs, Pécs, Hungary Export Date: 25 September 2023 CODEN: JDENA Correspondence Address: Borbély, J.; Postal address: Department of Prosthodontics, Szentkirályi utca 47., Hungary; email: drborbelyj@gmail.com AB - This network meta-analysis (NMA) aimed to compare the complete-arch scanning accuracy of different intraoral scanners (IOSs) to that of reference standard tessellation language (STL) files.Studies comparing the trueness and precision of IOS STL files with those of reference STL scans for different arch types (dentate, edentulous, completely edentulous with implants, and partially edentulous with implants) were included in this study.An electronic search of five databases restricted to the English Language was conducted in October 2021.A total of 3,815 studies were identified, of which 114 were eligible for inclusion. After study selection and data extraction, pair-wise comparison and NMA were performed to define the accuracy of scanning for four arch subgroups using four outcomes (trueness and precision expressed as mean absolute deviation and root mean square values). Cochrane guidelines and the QUADAS-2 tool were used to assess the risk of bias. GRADE was used for certainty assessment.Fifty-three articles were included in this NMA. Altogether, 26 IOSs were compared directly and indirectly in 10 network systems. The accuracy of IOSs scans were not significantly different from the reference scans for dentate arches (three IOSs), edentulous arches (three IOSs), and completely edentulous arches with implants (one IOS). The accuracy of the IOSs was significantly different from the reference scans for partially edentulous arches with implants. Significant accuracy differences were found between the IOSs, regardless of clinical scenarios.The accuracy of complete-arch scanning by IOSs differs based on clinical scenarios.Different IOSs should be used according to the complete arch type. LA - English DB - MTMT ER - TY - JOUR AU - Tajti, Péter AU - Sólyom, Eleonóra AU - Czumbel, László Márk AU - Szabó, Bence AU - Fazekas, Réka AU - Németh, Orsolya AU - Hermann, Péter AU - Gerber, Gábor AU - Hegyi, Péter AU - Mikulás, Krisztina Ágnes TI - Monolithic zirconia as a valid alternative to metal-ceramic for implant-supported single crowns in the posterior region: A systematic review and meta-analysis of randomized controlled trials JF - JOURNAL OF PROSTHETIC DENTISTRY J2 - J PROSTHET DENT VL - 2023 PY - 2023 PG - 9 SN - 0022-3913 DO - 10.1016/j.prosdent.2023.05.006 UR - https://m2.mtmt.hu/api/publication/34032843 ID - 34032843 AB - Technical complication rates of standard metal-ceramic implant-supported posterior restorations are relatively high. Whether monolithic zirconia crowns represent a more successful alternative is unclear.The purpose of this systematic review and meta-analysis was to compare the clinical outcomes of posterior monolithic zirconia and metal-ceramic implant-supported single crowns.A search was conducted in MEDLINE, Scopus, Embase, Web of Science, and CENTRAL databases for randomized controlled trials up to April 2023 with a follow-up time of at least 1 year. Restoration and implant survival and failure rates, marginal bone loss (MBL), bleeding on probing (BOP), and technical complications were analyzed by 2 reviewers. Statistical analyses were conducted using the R-statistics software program. The risk of bias was assessed by the Cochrane Risk of Bias Tool 2 (RoB 2), and the certainty of evidence by the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) approach.A total of 11 out of 2030 records were identified by title and abstract, and 4 records were included after full-text analysis. The statistical analysis revealed no significant difference in MBL (MD -0.11, 95% CI: [-0.25; 0.03]), BOP (OR 0.66, 95% CI: [0.25; 1.77]), or implant failure (OR 1.30, 95% CI: [0.24; 7.08]). Monolithic zirconia presented significantly less chipping over 1 year (OR 0.17, 95% CI: [0.03; 0.99]). The chipping rate was 0% for monolithic zirconia and 7.61% for metal-ceramic. Based on a narrative review, the restoration survival rate was 97.5% in the monolithic zirconia group and 99.1% in the metal-ceramic group.Monolithic zirconia showed favorable short-term survival rates and had significantly less chipping over 1 year. Regarding MBL, BOP, and failure rates, both restoration types presented similar results at the 1-year follow-up. LA - English DB - MTMT ER - TY - JOUR AU - Németh, Anna AU - Vitai, Viktória AU - Czumbel, László Márk AU - Szabó, Bence AU - Varga, Gábor AU - Kerémi, Beáta AU - Hegyi, Péter AU - Hermann, Péter AU - Borbély, Judit TI - Clear guidance to select the most accurate technologies for 3D printing dental models - A network meta-analysis JF - JOURNAL OF DENTISTRY J2 - J DENTISTRY VL - 134 PY - 2023 PG - 12 SN - 0300-5712 DO - 10.1016/j.jdent.2023.104532 UR - https://m2.mtmt.hu/api/publication/33788836 ID - 33788836 AB - Thus far, the findings of numerous studies conducted on the accuracy of three-dimensional (3D) printed dental models are conflicting. Therefore, the aim of the network meta-analysis (NMA) is to determine the accuracy of 3D printed dental models compared with digital reference models.Studies comparing the accuracy of 3D printed full-arch dental models manufactured using different printing techniques to initial STL files were included.This study was registered in PROSPERO (CRD42021285863). An electronic search was performed across four databases in November 2021, and search was restricted to the English language.A systematic search was conducted based on a prespecified search query. 16,303 articles were pooled after the removal of the duplicates. Following study selection and data extraction, 11 eligible studies were included in the NMA in 6 subgroups. The outcomes were specified as trueness and precision and expressed as root mean square (RMS) and absolute mean deviation values. Seven printing technologies were analyzed: stereolithography (SLA), digital light processing (DLP), fused deposition modeling/fused filament fabrication (FDM/FFF), MultiJet, PolyJet, continuous liquid interface production (CLIP), and LCD technology. The QUADAS-2 and GRADE were used to evaluate the risk of bias and certainty of evidence.SLA, DLP, and PolyJet technologies were the most accurate in producing precise full-arch dental models.The findings of the NMA suggest that SLA, DLP, and PolyJet technologies are sufficiently accurate for full-arch dental model production for prosthodontic purposes. In contrast, FDM/FFF, CLIP, and LCD technologies are less suitable for manufacturing dental devices. LA - English DB - MTMT ER -