TY - THES AU - Sinka, Izabella TI - Antiproliferative and antimetastatic properties of modified estradiol analogs against gynecological cancer cell lines [Módosított ösztradiol analógok antiproliferatív és antimetasztatikus hatása nőgyógyászati tumoros sejtvonalakon] PB - Szegedi Tudományegyetem (SZTE) PY - 2020 SP - 49 DO - 10.14232/phd.10502 UR - https://m2.mtmt.hu/api/publication/31318244 ID - 31318244 N1 - Kaohsiung Medical University College of Pharmacy Graduate Institute of Natural Products LA - English DB - MTMT ER - TY - JOUR AU - Tastan, Pelin AU - Hajdú, Zsuzsanna AU - Kúsz, Norbert AU - Zupkó, István AU - Sinka, Izabella AU - Kivcak, Bijen AU - Hohmann, Judit TI - Sesquiterpene Lactones and Flavonoids from Psephellus pyrrhoblepharus with Antiproliferative Activity on Human Gynecological Cancer Cell Lines JF - MOLECULES J2 - MOLECULES VL - 24 PY - 2019 IS - 17 PG - 9 SN - 1420-3049 DO - 10.3390/molecules24173165 UR - https://m2.mtmt.hu/api/publication/30779917 ID - 30779917 N1 - Cited By :7 Export Date: 9 August 2022 CODEN: MOLEF LA - English DB - MTMT ER - TY - JOUR AU - Mótyán, Gergő AU - Mérai, László AU - Kiss, Márton Attila AU - Schelz, Zsuzsanna AU - Sinka, Izabella AU - Zupkó, István AU - Nagyné Frank, Éva TI - Microwave-assisted synthesis of biologically relevant steroidal 17- exo -pyrazol-5'-ones from a norpregnene precursor by a side-chain elongation/heterocyclization sequence JF - BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY J2 - BEILSTEIN J ORG CHEM VL - 14 PY - 2018 SP - 2589 EP - 2596 PG - 8 SN - 1860-5397 DO - 10.3762/bjoc.14.236 UR - https://m2.mtmt.hu/api/publication/30308485 ID - 30308485 LA - English DB - MTMT ER - TY - JOUR AU - Sinka, Izabella AU - Kiss, Anita AU - Mernyák, Erzsébet AU - Wölfling, János AU - Schneider, Gyula AU - Ocsovszki, Imre AU - Kuo, C-Y AU - Wang, H-C AU - Zupkó, István TI - Antiproliferative and antimetastatic properties of 3-benzyloxy-16-hydroxymethylene-estradiol analogs against breast cancer cell lines JF - EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES J2 - EUR J PHARM SCI VL - 123 PY - 2018 SP - 362 EP - 370 PG - 9 SN - 0928-0987 DO - 10.1016/j.ejps.2018.07.029 UR - https://m2.mtmt.hu/api/publication/3406423 ID - 3406423 N1 - Department of Pharmacodynamics and Biopharmacy, University of Szeged, Szeged, Hungary Department of Organic Chemistry, University of Szeged, Szeged, Hungary Department of Biochemistry, University of Szeged, Szeged, Hungary Graduate Institute of Natural Products, Kaohsiung Medical University, Kaohsiung City, Taiwan Interdisciplinary Centre for Natural Products, University of Szeged, Szeged, Hungary Cited By :1 Export Date: 11 February 2020 CODEN: EPSCE Correspondence Address: Zupkó, I.; Department of Pharmacodynamics and Biopharmacy, University of Szeged, Szeged, Eövtös u. 6, Hungary; email: zupko@pharm.u-szeged.hu Chemicals/CAS: cisplatin, 15663-27-1, 26035-31-4, 96081-74-2; gelatinase A, 146480-35-5; gelatinase B, 146480-36-6; estradiol, 50-28-2; Antineoplastic Agents; Estradiol; Focal Adhesion Kinase 1; Protein Kinase Inhibitors; PTK2 protein, human Funding details: GINOP-2.3.2-15-2016-00012, GINOP-2.3.2-15-2016-00038 Funding details: K109293, K113150 Funding details: Ministry of Science and Technology, Taiwan, MOST106-2911-I-037-504 Funding details: Hungarian Scientific Research Fund Funding text 1: The authors are grateful for financial support from the Hungarian Scientific Research Fund (OTKA K109293 and K113150 ). Financial support from the Economic Development and Innovation Operative Programs ( GINOP-2.3.2-15-2016-00012 and GINOP-2.3.2-15-2016-00038 ) and Taiwan Ministry of Science and Technology Grant ( MOST106-2911-I-037-504 ) is gratefully acknowledged. Appendix A Funding Agency and Grant Number: Hungarian Scientific Research FundOrszagos Tudomanyos Kutatasi Alapprogramok (OTKA) [OTKA K109293, K113150]; Economic Development and Innovation Operative Programs [GINOP-2.3.2-15-2016-00012, GINOP-2.3.2-15-2016-00038]; Taiwan Ministry of Science and Technology Grant [MOST106-2911-I-037-504] Funding text: The authors are grateful for financial support from the Hungarian Scientific Research Fund (OTKA K109293 and K113150). Financial support from the Economic Development and Innovation Operative Programs (GINOP-2.3.2-15-2016-00012 and GINOP-2.3.2-15-2016-00038) and Taiwan Ministry of Science and Technology Grant (MOST106-2911-I-037-504) is gratefully acknowledged. Department of Pharmacodynamics and Biopharmacy, University of Szeged, Szeged, Hungary Department of Organic Chemistry, University of Szeged, Szeged, Hungary Department of Biochemistry, University of Szeged, Szeged, Hungary Graduate Institute of Natural Products, Kaohsiung Medical University, Kaohsiung City, Taiwan Interdisciplinary Centre for Natural Products, University of Szeged, Szeged, Hungary Cited By :2 Export Date: 29 August 2020 CODEN: EPSCE Correspondence Address: Zupkó, I.; Department of Pharmacodynamics and Biopharmacy, University of Szeged, Szeged, Eövtös u. 6, Hungary; email: zupko@pharm.u-szeged.hu Chemicals/CAS: cisplatin, 15663-27-1, 26035-31-4, 96081-74-2; gelatinase A, 146480-35-5; gelatinase B, 146480-36-6; estradiol, 50-28-2; Antineoplastic Agents; Estradiol; Focal Adhesion Kinase 1; Protein Kinase Inhibitors; PTK2 protein, human Funding details: GINOP-2.3.2-15-2016-00012, GINOP-2.3.2-15-2016-00038 Funding details: MOST106-2911-I-037-504 Funding details: Hungarian Scientific Research Fund, OTKA Funding details: Hungarian Scientific Research Fund, OTKA, K109293, K113150 Funding text 1: The authors are grateful for financial support from the Hungarian Scientific Research Fund (OTKA K109293 and K113150 ). Financial support from the Economic Development and Innovation Operative Programs ( GINOP-2.3.2-15-2016-00012 and GINOP-2.3.2-15-2016-00038 ) and Taiwan Ministry of Science and Technology Grant ( MOST106-2911-I-037-504 ) is gratefully acknowledged. Department of Pharmacodynamics and Biopharmacy, University of Szeged, Szeged, Hungary Department of Organic Chemistry, University of Szeged, Szeged, Hungary Department of Biochemistry, University of Szeged, Szeged, Hungary Graduate Institute of Natural Products, Kaohsiung Medical University, Kaohsiung City, Taiwan Interdisciplinary Centre for Natural Products, University of Szeged, Szeged, Hungary Cited By :2 Export Date: 10 January 2021 CODEN: EPSCE Correspondence Address: Zupkó, I.; Department of Pharmacodynamics and Biopharmacy, University of Szeged, Szeged, Eövtös u. 6, Hungary; email: zupko@pharm.u-szeged.hu Chemicals/CAS: cisplatin, 15663-27-1, 26035-31-4, 96081-74-2; gelatinase A, 146480-35-5; gelatinase B, 146480-36-6; estradiol, 50-28-2; Antineoplastic Agents; Estradiol; Focal Adhesion Kinase 1; Protein Kinase Inhibitors; PTK2 protein, human Funding details: GINOP-2.3.2-15-2016-00012, GINOP-2.3.2-15-2016-00038 Funding details: MOST106-2911-I-037-504 Funding details: Hungarian Scientific Research Fund, OTKA Funding details: Hungarian Scientific Research Fund, OTKA, K109293, K113150 Funding text 1: The authors are grateful for financial support from the Hungarian Scientific Research Fund (OTKA K109293 and K113150 ). Financial support from the Economic Development and Innovation Operative Programs ( GINOP-2.3.2-15-2016-00012 and GINOP-2.3.2-15-2016-00038 ) and Taiwan Ministry of Science and Technology Grant ( MOST106-2911-I-037-504 ) is gratefully acknowledged. Department of Pharmacodynamics and Biopharmacy, University of Szeged, Szeged, Hungary Department of Organic Chemistry, University of Szeged, Szeged, Hungary Department of Biochemistry, University of Szeged, Szeged, Hungary Graduate Institute of Natural Products, Kaohsiung Medical University, Kaohsiung City, Taiwan Interdisciplinary Centre for Natural Products, University of Szeged, Szeged, Hungary Cited By :2 Export Date: 31 May 2021 CODEN: EPSCE Correspondence Address: Zupkó, I.; Department of Pharmacodynamics and Biopharmacy, Szeged, Eövtös u. 6, Hungary; email: zupko@pharm.u-szeged.hu LA - English DB - MTMT ER - TY - JOUR AU - Kiss, Anita AU - Mernyák, Erzsébet AU - Wölfling, János AU - Sinka, Izabella AU - Zupkó, István AU - Schneider, Gyula TI - Stereoselective synthesis of the four 16-hydroxymethyl-3-methoxy- and 16-hydroxymethyl-3-benzyloxy-13α-estra-1,3,5(10)-trien-17-ol isomers and their antiproliferative activities JF - STEROIDS J2 - STEROIDS VL - 134 PY - 2018 SP - 67 EP - 77 PG - 11 SN - 0039-128X DO - 10.1016/j.steroids.2018.02.008 UR - https://m2.mtmt.hu/api/publication/3361749 ID - 3361749 LA - English DB - MTMT ER - TY - JOUR AU - Vlaisavljević, Sanja AU - Šibul, Filip AU - Sinka, Izabella AU - Zupkó, István AU - Ocsovszki, Imre AU - Jovanović-Šanta, Suzana TI - Chemical composition, antioxidant and anticancer activity of licorice from Fruska Gora locality JF - INDUSTRIAL CROPS AND PRODUCTS J2 - IND CROP PROD VL - 112 PY - 2018 SP - 217 EP - 224 PG - 8 SN - 0926-6690 DO - 10.1016/j.indcrop.2017.11.050 UR - https://m2.mtmt.hu/api/publication/3311152 ID - 3311152 LA - English DB - MTMT ER - TY - JOUR AU - Sinka, Izabella AU - Mernyák, Erzsébet AU - Kiss, Anita AU - Schneider, Gyula AU - Wölfling, János AU - Ocsovszki, Imre AU - Kuo, CY AU - Wang, HC AU - Zupkó, István TI - Investigation of anticancer properties of D-ring modified estrane analogs against a panel of breast cancer cell lines JF - ACTA PHARMACEUTICA HUNGARICA J2 - ACTA PHARM HUNG VL - 87 PY - 2017 SP - 213 EP - 214 PG - 2 SN - 0001-6659 UR - https://m2.mtmt.hu/api/publication/3316046 ID - 3316046 LA - English DB - MTMT ER - TY - JOUR AU - Kovács, Bernadett AU - Béni, Zoltán AU - Dékány, Miklós AU - Orbán-Gyapai, Orsolya AU - Sinka, Izabella AU - Zupkó, István AU - Hohmann, Judit AU - Ványolós, Attila TI - Chemical Analysis of the Edible Mushroom Tricholoma populinum: Steroids and Sulfinyladenosine Compounds JF - NATURAL PRODUCT COMMUNICATIONS J2 - NAT PROD COMMUN VL - 12 PY - 2017 IS - 10 SP - 1583 EP - 1584 PG - 2 SN - 1934-578X DO - 10.1177/1934578x1701201014 UR - https://m2.mtmt.hu/api/publication/3287305 ID - 3287305 N1 - Cited By :2 Export Date: 3 December 2019 Correspondence Address: Hohmann, J.; Department of Pharmacognosy, University of Szeged, Eötvös u. 6, Hungary; email: hohmann@pharm.u-szeged.hu LA - English DB - MTMT ER - TY - JOUR AU - Baji, Ádám AU - Kovács, Ferenc AU - Mótyán, Gergő AU - Schneider, Gyula AU - Wölfling, János AU - Sinka, Izabella AU - Zupkó, István AU - Ocsovszki, Imre AU - Nagyné Frank, Éva TI - Investigation of pH and substituent effects on the distribution ratio of novel steroidal ring D- and A-fused arylpyrazole regioisomers and evaluation of their cell-growth inhibitory effects in vitro JF - STEROIDS J2 - STEROIDS VL - 126 PY - 2017 SP - 35 EP - 49 PG - 15 SN - 0039-128X DO - 10.1016/j.steroids.2017.08.003 UR - https://m2.mtmt.hu/api/publication/3253932 ID - 3253932 LA - English DB - MTMT ER - TY - JOUR AU - Csábi, József AU - Martins, Ana AU - Sinka, Izabella AU - Csorba, Attila AU - Molnár, József AU - Zupkó, István AU - Tóth, Gábor AU - Tillekeratne, LMV AU - Hunyadi, Attila TI - Synthesis and in vitro evaluation of the antitumor potential and chemo-sensitizing activity of fluorinated ecdysteroid derivatives JF - MEDCHEMCOMM J2 - MEDCHEMCOMM VL - 7 PY - 2016 IS - 12 SP - 2282 EP - 2289 PG - 8 SN - 2040-2503 DO - 10.1039/c6md00431h UR - https://m2.mtmt.hu/api/publication/3114794 ID - 3114794 LA - English DB - MTMT ER -