@article{MTMT:34409947, title = {FRL and DAAM are required for lateral adhesion of interommatidial cells and patterning of the retinal floor}, url = {https://m2.mtmt.hu/api/publication/34409947}, author = {Gazsó-Gerhát, Gabriella and Gombos, Rita I and Tóth, Krisztina and Kaltenecker, Péter and Szikora, Szilárd and Bíró, Judit and Csapó, Enikő and Asztalos, Zoltán Imre and Mihály, József}, doi = {10.1242/dev.201713}, journal-iso = {DEVELOPMENT}, journal = {DEVELOPMENT}, volume = {150}, unique-id = {34409947}, issn = {0950-1991}, abstract = {Optical insulation of the unit eyes (ommatidia) is an important prerequisite of precise sight with compound eyes. Separation of the ommatidia is ensured by pigment cells that organize into a hexagonal lattice in the Drosophila eye, forming thin walls between the facets. Cell adhesion, mediated by apically and latero-basally located junctional complexes, is crucial for stable attachment of these cells to each other and the basal lamina. Whereas former studies have focused on the formation and remodelling of the cellular connections at the apical region, here, we report a specific alteration of the lateral adhesion of the lattice cells, leaving the apical junctions largely unaffected. We found that DAAM and FRL, two formin-type cytoskeleton regulatory proteins, play redundant roles in lateral adhesion of the interommatidial cells and patterning of the retinal floor. We show that formin-dependent cortical actin assembly is crucial for latero-basal sealing of the ommatidial lattice. We expect that the investigation of these previously unreported eye phenotypes will pave the way toward a better understanding of the three-dimensional aspects of compound eye development.}, year = {2023}, eissn = {1477-9129}, orcid-numbers = {Csapó, Enikő/0009-0001-1980-4020} } @article{MTMT:31595814, title = {The Activities of the Gelsolin Homology Domains of Flightless-I in Actin Dynamics}, url = {https://m2.mtmt.hu/api/publication/31595814}, author = {Pintér, Réka and Huber, Tamás and Bukovics, Péter and Gaszler, Péter and Leipold Vig, Andrea and Szütsné Tóth, Mónika Ágnes and Gazsó-Gerhát, Gabriella and Farkas, Dávid and Migh, Ede and Mihály, József and Bugyi, Beáta}, doi = {10.3389/fmolb.2020.575077}, journal-iso = {FRONT MOL BIOSCI}, journal = {FRONTIERS IN MOLECULAR BIOSCIENCES}, volume = {7}, unique-id = {31595814}, year = {2020}, eissn = {2296-889X} } @article{MTMT:31334081, title = {Assembly of a persistent apical actin network by the formin Frl/Fmnl tunes epithelial cell deformability}, url = {https://m2.mtmt.hu/api/publication/31334081}, author = {Dehapiot, Benoit and Clément, Raphaël and Alégot, Hervé and Gazsó-Gerhát, Gabriella and Philippe, Jean-Marc and Lecuit, Thomas}, doi = {10.1038/s41556-020-0524-x}, journal-iso = {NAT CELL BIOL}, journal = {NATURE CELL BIOLOGY}, volume = {22}, unique-id = {31334081}, issn = {1465-7392}, year = {2020}, eissn = {1476-4679}, pages = {791-802} } @misc{MTMT:30855502, title = {Redundant role of DAAM and FRL formins in pigment cell development in the Drosophila eye}, url = {https://m2.mtmt.hu/api/publication/30855502}, author = {Gazsó-Gerhát, Gabriella and Gombos, R and Szikora, S and Toth, K and Foldi, I and Mihaly, J}, unique-id = {30855502}, year = {2019} } @misc{MTMT:30744938, title = {Examination of the redundancy between DAAM and FRL formins during pigment cell development in the Drosophila eye}, url = {https://m2.mtmt.hu/api/publication/30744938}, author = {Gazsó-Gerhát, Gabriella and Gombos, R and Szikora, S and Mihaly, J}, unique-id = {30744938}, year = {2019} } @CONFERENCE{MTMT:3414696, title = {Examination of the redundancy between DAAM and FRL during eye development in Drosohila melanogaster}, url = {https://m2.mtmt.hu/api/publication/3414696}, author = {Gazsó-Gerhát, Gabriella and Gombos, R and Szikora, S and Mihaly, J}, booktitle = {NEUROFLY 2018}, unique-id = {3414696}, year = {2018} } @misc{MTMT:3241341, title = {Investigation of the redundancy between two formin proteins dDAAM and FRL during eye development in Drosophila melanogaster}, url = {https://m2.mtmt.hu/api/publication/3241341}, author = {Gazsó-Gerhát, Gabriella and Gombos, R and Mihaly, J}, unique-id = {3241341}, year = {2017} } @misc{MTMT:3178637, title = {The Formin DAAM functions as Molecular Effector of the Planar Cell Polaritry Pathway during Axonal Development in Drososphila}, url = {https://m2.mtmt.hu/api/publication/3178637}, author = {Gombos, R and Migh, E and Gazsó-Gerhát, Gabriella and Mihaly, J}, unique-id = {3178637}, year = {2016} } @article{MTMT:3178611, title = {A Down-szindrómás gyermekek testi fejlettsége}, url = {https://m2.mtmt.hu/api/publication/3178611}, author = {Gazsó-Gerhát, Gabriella and Muzsnai, Ágota and Zsákai, Annamária and Bodzsár, Éva}, journal-iso = {GYERMEKGYÓGYÁSZATI TOVÁBBKÉPZŐ SZEMLE}, journal = {GYERMEKGYÓGYÁSZATI TOVÁBBKÉPZŐ SZEMLE}, volume = {21}, unique-id = {3178611}, issn = {1585-4396}, year = {2016}, pages = {120-124}, orcid-numbers = {Zsákai, Annamária/0000-0001-8880-2056} } @misc{MTMT:3085774, title = {Identification of the Genetic Interaction Partners of the Formin dDAAM Required for Axonal Growth in Drosophila}, url = {https://m2.mtmt.hu/api/publication/3085774}, author = {Gazsó-Gerhát, Gabriella and Nagy, V and Gombos, R and Földi, I and Mihaly, J}, unique-id = {3085774}, year = {2015}, pages = {15-15} }