TY  - JOUR
AU  - Imre, Gergely
AU  - Takács, Bertalan Vilmos
AU  - Czipa, Erik
AU  - Drubi, Andrea
AU  - Jaksa, Gábor
AU  - Latinovics, Dóra
AU  - Nagy, Andrea
AU  - Karkas, Réka
AU  - Hudoba, Liza
AU  - Vásárhelyi, Bálint Márk
AU  - Pankotai-Bodó, Gabriella
AU  - Blastyák, András
AU  - Hegedűs, Zoltán
AU  - Germán, Péter
AU  - Bálint, Balázs
AU  - Abdullah, Khaldoon Sadiq Ahmed
AU  - Kopasz, Anna Georgina
AU  - Kovács, Anita Kármen
AU  - Nagy, László
AU  - Sükösd, Farkas
AU  - Pintér, Lajos
AU  - Rülicke, Thomas
AU  - Barta, Endre
AU  - Nagy, István
AU  - Haracska, Lajos
AU  - Mátés, Lajos
TI  - Prolonged activity of the transposase helper may raise safety concerns during DNA transposon-based gene therapy
JF  - MOLECULAR THERAPY-METHODS AND CLINICAL DEVELOPMENT
J2  - MOL THER-METH CLIN D
VL  - 29
PY  - 2023
SP  - 145
EP  - 159
PG  - 15
SN  - 2329-0501
DO  - 10.1016/j.omtm.2023.03.003
UR  - https://m2.mtmt.hu/api/publication/33708483
ID  - 33708483
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Kopasz, Anna Georgina
AU  - Pusztai, Dávid
AU  - Karkas, Réka
AU  - Hudoba, Liza
AU  - Abdullah, Khaldoon Sadiq Ahmed
AU  - Imre, Gergely
AU  - Pankotai-Bodó, Gabriella
AU  - Migh, Ede
AU  - Nagy, Andrea
AU  - Kriston, András
AU  - Germán, Péter
AU  - Drubi, Andrea
AU  - Molnár, Anna
AU  - Fekete, Ildikó
AU  - Dani, Virág Éva
AU  - Ocsovszki, Imre
AU  - Puskás, László
AU  - Horváth, Péter
AU  - Sükösd, Farkas
AU  - Mátés, Lajos
TI  - A versatile transposon-based technology to generate loss- and gain-of-function phenotypes in the mouse liver
JF  - BMC BIOLOGY
J2  - BMC BIOL
VL  - 20
PY  - 2022
IS  - 1
PG  - 17
SN  - 1741-7007
DO  - 10.1186/s12915-022-01262-x
UR  - https://m2.mtmt.hu/api/publication/32773206
ID  - 32773206
N1  - Funding Agency and Grant Number: Momentum Programme of the Hungarian Academy of Sciences [LP2015-5/2015]; National Research, Development and Innovation Office (Hungary)National Research, Development & Innovation Office (NRDIO) - Hungary [GINOP-2.3.2-15-2016-00024]; LENDULET-BIOMAG [2018342]; European Regional Development FundEuropean Commission [GINOP-2.3.2-15-201600026]; COMPASS-ERA PerMed H2020; CZI Deep Visual Proteomics; H2020-DiscovAir; ELKH-Excellence grant; New National Excellence Program of the Ministry for Innovation and Technology from the National Research, Development and Innovation Fund [UNKP-20-3-SZTE-84]; Szeged Scientists Academy under Hungarian Ministry of Innovation and Technology [FEIF/646-4/2021-ITM_SZERZ]; New National Excellence Program of the Ministry for Innovation and Technology of Hungary [UNKP-20-2 -SZTE-438]
            Funding text: This work was supported by the Momentum Programme of the Hungarian Academy of Sciences [LP2015-5/2015] and by the National Research, Development and Innovation Office (Hungary) grant [GINOP-2.3.2-15-2016-00024]. PH, EM, and AK acknowledge support from the LENDULET-BIOMAG Grant [2018342], from the European Regional Development Fund (GINOP-2.3.2-15-201600026), from COMPASS-ERA PerMed H2020, from CZI Deep Visual Proteomics, from H2020-DiscovAir, and from ELKH-Excellence grant. RK was supported by the UNKP-20-3-SZTE-84 New National Excellence Program of the Ministry for Innovation and Technology from the source of the National Research, Development and Innovation Fund. AGK was supported by the Szeged Scientists Academy under the sponsorship of the Hungarian Ministry of Innovation and Technology (FEIF/646-4/2021-ITM_SZERZ) and the New National Excellence Program of the Ministry for Innovation and Technology of Hungary (UNKP-20-2 -SZTE-438).
LA  - English
DB  - MTMT
ER  - 

TY  - GEN
AU  - Karkas, R
AU  - Blastyák, A
AU  - Hudoba, L
AU  - Bakné, Drubi A
AU  - Imre, Gergely
AU  - Mátés, L
TI  - Comparison of the DNA transposon-based approaches in the gene therapy of the Mouse Model of Tyrosinemia Type I
PY  - 2021
UR  - https://m2.mtmt.hu/api/publication/32528660
ID  - 32528660
LA  - English
DB  - MTMT
ER  - 

TY  - GEN
AU  - Imre, Gergely
AU  - Hudoba, L
AU  - Nagy, A
AU  - Balazs, B
AU  - Nagy, I
AU  - Rülicke, T
AU  - Mates, L
TI  - Somatic-transgenic mouse model to introduce random genome-wide deletions
PY  - 2016
UR  - https://m2.mtmt.hu/api/publication/31614585
ID  - 31614585
LA  - English
DB  - MTMT
ER  - 

TY  - GEN
AU  - Nagy, A
AU  - Hudoba, L
AU  - Imre, Gergely
AU  - Hegedus, K
AU  - Fekete, I
AU  - Rulicke, T
AU  - Mates, L
TI  - A novel transgenic organ model to screen for the genetic drivers of tumorgenesis
PY  - 2015
UR  - https://m2.mtmt.hu/api/publication/31614602
ID  - 31614602
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Nagy, Andrea
AU  - Imre, Gergely
AU  - Mátés, Lajos
TI  - Transposon-based gene delivery vectors for gene therapy
JF  - ACTA BIOLOGICA SZEGEDIENSIS
J2  - ACTA BIOL SZEGED
VL  - 59
PY  - 2015
IS  - Suppl 2
SP  - 247
EP  - 260
PG  - 14
SN  - 1588-385X
UR  - https://m2.mtmt.hu/api/publication/2998018
ID  - 2998018
AB  - The first gene therapy clinical trials were initiated more than two decades ago thanks to the previous development of viral vectors that allow high efficiency gene transfer into mammalian cells. Since then the application of viral gene transfer has been a successful treatment option for a variety of diseases. Hematopoietic stem cells (HSCs) represent the most frequently targeted cell population for the treatment of severe monogenic diseases as their gene therapeutic correction is a valid alternative to conventional HSC transplantation when a compatible donor is not available. Indeed, viral gene transfer was successfully applied in HSC-based ex vivo gene therapy of the blood and immune systems, albeit several studies have exposed serious adverse effects that were caused by the therapeutic vector induced inappropriate activation of proto-oncogenes. After these failures, researchers have developed new types of randomly integrating vectors that have proven safer in preclinical studies, which is consistent with interim reports of clinical trials also foreshadowing that they potentially have an improved safety profile. This review focuses on new and clinically relevant DNA transposon-based gene delivery vectors, and compares their properties with those of the old and new generation viral vectors.
LA  - English
DB  - MTMT
ER  - 

TY  - CHAP
AU  - Nagy, Gábor
AU  - Csernetics, Árpád
AU  - Imre, Gergely
AU  - Farkas, Anita
AU  - Vágvölgyi, Csaba
AU  - Papp, Tamás
ED  - Škrbić, B
ED  - Milanović, S
TI  - Characterization of HMG-CoA reductase genes of the carotenoid producing Mucor circinelloides
T2  - 2nd CEFSER (Center of Excellence in Food Safety and Emerging Risks) Workshop Persistant Organic Pollutants in Food and the Environment [and] 26th Symposium on Recent Developments in Dairy Technology [and] BIOXEN seminar Novel Approaches for Environmental Protection
PB  - University of Novi Sad, Faculty of Technical Sciences
CY  - Novi Sad
SN  - 9788680995939
PY  - 2011
SP  - 54
UR  - https://m2.mtmt.hu/api/publication/1945980
ID  - 1945980
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Nagy, Gábor
AU  - Farkas, Anita
AU  - Imre, Gergely
AU  - Csernetics, Árpád
AU  - Vágvölgyi, Csaba
AU  - Papp, Tamás
TI  - HMG-CoA reductase genes of the carotenoid producing Mucor circinelloides
JF  - ACTA MICROBIOLOGICA ET IMMUNOLOGICA HUNGARICA
J2  - ACTA MICROBIOL IMMUNOL HUNG
VL  - 58
PY  - 2011
IS  - Supplement 1
SP  - 190
SN  - 1217-8950
UR  - https://m2.mtmt.hu/api/publication/1945835
ID  - 1945835
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Nagy, Gábor
AU  - Imre, Gergely
AU  - Csernetics, Árpád
AU  - Petkovits, Tamás
AU  - Nagy, László
AU  - Szekeres, András
AU  - Vágvölgyi, Csaba
AU  - Papp, Tamás
TI  - A prenyl pyrophosphate synthase gene from the zygomycete fungus, Gilbertella persicaria
JF  - ACTA BIOLOGICA SZEGEDIENSIS
J2  - ACTA BIOL SZEGED
VL  - 55
PY  - 2011
IS  - 1
SP  - 7
EP  - 12
PG  - 6
SN  - 1588-385X
UR  - https://m2.mtmt.hu/api/publication/1939772
ID  - 1939772
N1  - Megjegyzés-22370108
Chemicals/CAS: astaxanthin, 472-61-7; beta carotene, 7235-40-7; farnesyl trans transferase, 9032-58-0
Megjegyzés-23214237
N1 : Chemicals/CASastaxanthin, 472-61-7; beta carotene, 7235-40-7; farnesyl trans transferase, 9032-58-0
Department of Microbiology, University of Szeged, Szeged, Hungary            
            FumoPrep Ltd., Mórahalom, Hungary            
            Export Date: 17 July 2020            
            CODEN: ABSCC            
            Correspondence Address: Papp, T.; Department of Microbiology, University of Szeged, Szeged, Hungary; email: pappt@bio.u-szeged.hu            
            Chemicals/CAS: astaxanthin, 472-61-7; beta carotene, 7235-40-7; farnesyl trans transferase, 9032-58-0
LA  - English
DB  - MTMT
ER  - 

TY  - CHAP
AU  - Nagy, Gábor
AU  - Csernetics, Árpád
AU  - Imre, Gergely
AU  - Vágvölgyi, Csaba
AU  - Papp, Tamás
ED  - Dékány, Imre
TI  - Characterization of HMG-CoA reductase genes in Mucor circinelloides
T2  - ISIRR 2010 - 11th International Symposium "Interdisciplinary Regional Research"
PB  - MTA Szegedi Területi Bizottság
CY  - Szeged
SN  - 9789635086009
PY  - 2010
UR  - https://m2.mtmt.hu/api/publication/1968802
ID  - 1968802
LA  - English
DB  - MTMT
ER  -