TY - JOUR AU - Furko, Monika AU - Detsch, Rainer AU - Horváth, Zsolt Endre AU - Balázsi, Katalin AU - Boccaccini, Aldo R. AU - Balázsi, Csaba TI - Amorphous, Carbonated Calcium Phosphate and Biopolymer-Composite-Coated Si3N4/MWCNTs as Potential Novel Implant Materials JF - NANOMATERIALS J2 - NANOMATERIALS-BASEL VL - 14 PY - 2024 IS - 3 PG - 16 SN - 2079-4991 DO - 10.3390/nano14030279 UR - https://m2.mtmt.hu/api/publication/34672527 ID - 34672527 LA - English DB - MTMT ER - TY - JOUR AU - Kaou, Maroua Houria AU - Furko, Monika AU - Ben Zine, Haroune Rachid AU - Balázsi, Katalin AU - Balázsi, Csaba TI - Morphological and structural evaluation of spark plasma sintered calcium silicate ceramics JF - INTERNATIONAL JOURNAL OF APPLIED CERAMIC TECHNOLOGY J2 - INT J APPL CERAM TEC VL - in press PY - 2024 SP - in press PG - 13 SN - 1546-542X DO - 10.1111/ijac.14684 UR - https://m2.mtmt.hu/api/publication/34555216 ID - 34555216 AB - Calcium silicate ceramics were successfully prepared at various temperatures by spark plasma sintering technique (SPS) using two different compositions, and their morphological and structural characteristics were thoroughly analyzed and compared by scanning electron microscope, X-ray diffraction, and apparent density measurements. The effect of the sintering method and temperature on microstructural properties has also been studied. The sintered samples prepared by SPS through a heat input of 800 degrees C showed the highest densification as results 800 degrees C was suggested as optimum sintering temperature. Different phases presented in pseudo-wollastonite, wollastonite, and triclinic Ca3(SiO4)O have been observed in the case of 50C50C with lowest porosity similar to 6%$\sim \;6\% $ and highest density 2.6 g/cm3, whereas the composition 10C90S resulted in a fully amorphous material presented in granular microstructure with density of 1.7 g/cm3.Schematic view of calcium silicate preparationimage LA - English DB - MTMT ER - TY - JOUR AU - Kaou, Maroua Houria AU - Furko, Monika AU - Balázsi, Katalin AU - Balázsi, Csaba TI - Advanced Bioactive Glasses: The Newest Achievements and Breakthroughs in the Area JF - NANOMATERIALS J2 - NANOMATERIALS-BASEL VL - 13 PY - 2023 IS - 16 PG - 33 SN - 2079-4991 DO - 10.3390/nano13162287 UR - https://m2.mtmt.hu/api/publication/34093975 ID - 34093975 AB - Bioactive glasses (BGs) are especially useful materials in soft and bone tissue engineering and even in dentistry. They can be the solution to many medical problems, and they have a huge role in the healing processes of bone fractures. Interestingly, they can also promote skin regeneration and wound healing. Bioactive glasses are able to attach to the bone tissues and form an apatite layer which further initiates the biomineralization process. The formed intermediate apatite layer makes a connection between the hard tissue and the bioactive glass material which results in faster healing without any complications or side effects. This review paper summarizes the most recent advancement in the preparation of diverse types of BGs, such as silicate-, borate- and phosphate-based bioactive glasses. We discuss their physical, chemical, and mechanical properties detailing how they affect their biological performances. In order to get a deeper insight into the state-of-the-art in this area, we also consider their medical applications, such as bone regeneration, wound care, and dental/bone implant coatings. LA - English DB - MTMT ER - TY - JOUR AU - Furko, Monika AU - Detsch, R. AU - Tolnai, István AU - Balázsi, Katalin AU - Boccaccini, A.R. AU - Balázsi, Csaba TI - Biomimetic mineralized amorphous carbonated calcium phosphate-polycaprolactone bioadhesive composites as potential coatings on implant materials JF - CERAMICS INTERNATIONAL J2 - CERAM INT VL - 49 PY - 2023 IS - 11 SP - 18565 EP - 18576 PG - 12 SN - 0272-8842 DO - 10.1016/j.ceramint.2023.02.231 UR - https://m2.mtmt.hu/api/publication/33767896 ID - 33767896 LA - English DB - MTMT ER - TY - JOUR AU - Furko, Monika AU - Balázsi, Katalin AU - Balázsi, Csaba TI - Calcium Phosphate Loaded Biopolymer Composites—A Comprehensive Review on the Most Recent Progress and Promising Trends JF - COATINGS J2 - COATINGS VL - 13 PY - 2023 IS - 2 PG - 30 SN - 2079-6412 DO - 10.3390/coatings13020360 UR - https://m2.mtmt.hu/api/publication/33649599 ID - 33649599 AB - Biocompatible ceramics are extremely important in bioengineering, and very useful in many biomedical or orthopedic applications because of their positive interactions with human tissues. There have been enormous efforts to develop bioceramic particles that cost-effectively meet high standards of quality. Among the numerous bioceramics, calcium phosphates are the most suitable since the main inorganic compound in human bones is hydroxyapatite, a specific phase of the calcium phosphates (CaPs). The CaPs can be applied as bone substitutes, types of cement, drug carriers, implants, or coatings. In addition, bioresorbable bioceramics have great potential in tissue engineering in their use as a scaffold that can advance the healing process of bones during the normal tissue repair process. On the other hand, the main disadvantages of bioceramics are their brittleness and poor mechanical properties. The newest advancement in CaPs doping with active biomolecules such as Mg, Zn, Sr, and others. Another set of similarly important materials in bioengineering are biopolymers. These include natural polymers such as collagen, cellulose acetate, gelatin, chitosan, and synthetic polymers, for example, polyvinyl pyrrolidone (PVP), polyvinyl alcohol (PVA), and polycaprolactone (PCL). Various types of polymer have unique properties that make them useful in different fields. The combination of CaP particles with different biopolymers gives rise to new opportunities for application, since their properties can be changed and adjusted to the given requirements. This review offers an insight into the most up-to-date advancements in the preparation and evaluation of different calcium phosphate–biopolymer composites, highlighting their application possibilities, which largely depend on the chemical and physical characteristics of CaPs and the applied polymer materials. Overall, these composites can be considered advanced materials in many important biomedical fields, with potential to improve the quality of healthcare and to assist in providing better outcomes as scaffolds in bone healing or in the integration of implants in orthopedic surgeries. LA - English DB - MTMT ER - TY - JOUR AU - Furko, Monika AU - Horváth, Zsolt Endre AU - Czömpöly, Ottó Sámuel AU - Balázsi, Katalin AU - Balázsi, Csaba TI - Biominerals Added Bioresorbable Calcium Phosphate Loaded Biopolymer Composites JF - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES J2 - INT J MOL SCI VL - 23 PY - 2022 IS - 24 PG - 17 SN - 1661-6596 DO - 10.3390/ijms232415737 UR - https://m2.mtmt.hu/api/publication/33327899 ID - 33327899 AB - Nanocrystalline calcium phosphate (CP) bioceramic coatings and their combination with biopolymers are innovative types of resorbable coatings for load-bearing implants that can promote the integration of metallic implants into human bodies. The nanocrystalline, amorphous CP particles are an advantageous form of the various calcium phosphate phases since they have a faster dissolution rate than that of crystalline hydroxyapatite. Owing to the biomineral additions (Mg, Zn, Sr) in optimized concentrations, the base CP particles became more similar to the mineral phase in human bones (dCP). The effect of biomineral addition into the CaP phases was thoroughly studied. The results showed that the shape, morphology, and amorphous characteristic slightly changed in the case of biomineral addition in low concentrations. The optimized dCP particles were then incorporated into a chosen polycaprolactone (PCL) biopolymer matrix. Very thin, non-continuous, rough layers were formed on the surface of implant substrates via the spin coating method. The SEM elemental mapping proved the perfect incorporation and distribution of dCP particles into the polymer matrix. The bioresorption rate of thin films was followed by corrosion measurements over a long period of time. The corrosion results indicated a faster dissolution rate for the dCP-PCL composite compared to the dCP and CP powder layers. LA - English DB - MTMT ER - TY - JOUR AU - Balázsi, Katalin AU - Varanasi, Dheeraj AU - Horváth, Zsolt Endre AU - Furko, Monika AU - Cinar, F. S. AU - Balázsi, Csaba TI - Effect of the pressureless post-sintering on the hot isostatic pressed Al2O3 prepared from the oxidized AlN powder JF - SCIENTIFIC REPORTS J2 - SCI REP VL - 12 PY - 2022 IS - 1 PG - 9 SN - 2045-2322 DO - 10.1038/s41598-022-12456-2 UR - https://m2.mtmt.hu/api/publication/32828021 ID - 32828021 LA - English DB - MTMT ER - TY - JOUR AU - Furko, Monika AU - Horváth, Zsolt Endre AU - Sulyok, Attila AU - Kovácsné Kis, Viktória AU - Balázsi, Katalin AU - Mihály, Judith AU - Balázsi, Csaba TI - Preparation and morphological investigation on bioactive ion-modified carbonated hydroxyapatite-biopolymer composite ceramics as coatings for orthopaedic implants JF - CERAMICS INTERNATIONAL J2 - CERAM INT VL - 48 PY - 2022 IS - 1 SP - 760 EP - 768 PG - 9 SN - 0272-8842 DO - 10.1016/j.ceramint.2021.09.156 UR - https://m2.mtmt.hu/api/publication/32251255 ID - 32251255 LA - English DB - MTMT ER - TY - JOUR AU - Furko, Monika AU - Horváth, Zsolt Endre AU - Mihály, Judith AU - Balázsi, Katalin AU - Balázsi, Csaba TI - Comparison of the Morphological and Structural Characteristic of Bioresorbable and Biocompatible Hydroxyapatite-Loaded Biopolymer Composites JF - NANOMATERIALS J2 - NANOMATERIALS-BASEL VL - 11 PY - 2021 IS - 12 PG - 17 SN - 2079-4991 DO - 10.3390/nano11123194 UR - https://m2.mtmt.hu/api/publication/32510025 ID - 32510025 AB - Calcium phosphate (CaP)-based ceramic–biopolymer composites can be regarded as innovative bioresorbable coatings for load-bearing implants that can promote the osseointegration process. The carbonated hydroxyapatite (cHAp) phase is the most suitable CaP form, since it has the highest similarity to the mineral phase in human bones. In this paper, we investigated the effect of wet chemical preparation parameters on the formation of different CaP phases and compared their morphological and structural characteristics. The results revealed that the shape and crystallinity of CaP particles were strongly dependent on the post-treatment methods, such as heat or alkaline treatment of as-precipitated powders. In the next step, the optimised cHAp particles have been embedded into two types of biopolymers, such as polyvinyl pyrrolidone (PVP) and cellulose acetate (CA). The pure polymer fibres and the cHAp–biopolymer composites were produced using a novel electrospinning technique. The SEM images showed the differences between the morphology and network of CA and PVP fibres as well as proved the successful attachment of cHAp particles. In both cases, the fibres were partially covered with cHAp clusters. The SEM measurements on samples after one week of immersion in PBS solution evidenced the biodegradability of the cHAp–biopolymer composites. LA - English DB - MTMT ER - TY - JOUR AU - Varanasi, Dheeraj AU - Furko, Monika AU - Balázsi, Katalin AU - Balázsi, Csaba TI - Processing of Al2O3-AlN Ceramics and Their Structural, Mechanical, and Tribological Characterization JF - MATERIALS J2 - MATERIALS VL - 14 PY - 2021 IS - 20 PG - 15 SN - 1996-1944 DO - 10.3390/ma14206055 UR - https://m2.mtmt.hu/api/publication/32399016 ID - 32399016 LA - English DB - MTMT ER -