@article{MTMT:34477406,
	title = {Volumetric alteration of brainstem in female migraineurs with and without aura},
	url = {https://m2.mtmt.hu/api/publication/34477406},
	author = {He, Mingchen and Kis-Jakab, Gréta and Komáromy, Hedvig and Perlaki, Gábor and Orsi, Gergely and Bosnyák, Edit and Rozgonyi, Renáta and John, Flóra and Trauninger, Anita and Eklicsné Lepenye, Katalin and Pfund, Zoltán},
	doi = {10.1016/j.clineuro.2023.108089},
	journal-iso = {CLIN NEUROL NEUROSUR},
	journal = {CLINICAL NEUROLOGY AND NEUROSURGERY},
	volume = {236},
	unique-id = {34477406},
	issn = {0303-8467},
	abstract = {Brainstem descending modulatory circuits have been postulated to be involved in migraine. Differences in brainstem volume between migraineurs and healthy controls have been demonstrated in previous research, nevertheless, the effect of migraine aura on brainstem volume is still uncertain. The aim of this study was to investigate the brainstem volume in migraineurs and examine the effect of migraine aura on brainstem volume.Our study included 90 female migraine patients without white matter lesions. (29 migraine patients with aura (MwA) and 61 migraine patients without aura (MwoA) and 32 age-matched female healthy controls (HC). Using the FreeSurfer image analysis suite, the volumes of the entire brainstem and its subfields (medulla, pons, and midbrain) were measured and compared between migraine subgroups (MwA vs. MwoA) and the healthy control group. The possible effects of migraine characteristics (i.e., disease duration and migraine attack frequency) on brainstem volume were also investigated.Migraineurs had greater medulla volume (MwoA 3552 ± 459 mm3, MwA 3424 ± 448 mm3) than healthy controls (3236 ± 411 mm3). Statistically, MwA vs. HC p = 0.040, MwoA vs. HC p = 0.002, MwA vs. MwoA p = 0.555. A significant positive correlation was found between disease duration and the volume of medulla in the whole migraine group (r = 0.334, p = 0.001). Neither the whole brainstem nor its subfields were significantly different in volume between migraine subgroups.Brainstem volume changes in migraine are mainly localized to the medulla and not specific to the presence of aura.},
	keywords = {morphometry; Magnetic Resonance Imaging; AURA; EPISODIC MIGRAINE; Brainstem volume},
	year = {2024},
	eissn = {1872-6968}
}

@article{MTMT:34413256,
	title = {Analysis of the ocular surface functional unit in episodic migraine},
	url = {https://m2.mtmt.hu/api/publication/34413256},
	author = {Patzkó, Ágnes and Csutak, Adrienne and Tóth, Noémi and Kölkedi, Zsófia and Pfund, Zoltán and Kis-Jakab, Gréta and Bosnyák, Edit and Rozgonyi, Renáta and Szalai, Eszter},
	doi = {10.1007/s00417-023-06324-6},
	journal-iso = {GRAEF ARCH CLIN EXP},
	journal = {GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY},
	volume = {262},
	unique-id = {34413256},
	issn = {0721-832X},
	abstract = {Migraine is a chronic neurovascular disease that affects the trigeminovascular system. The purpose of this study was to evaluate corneal subbasal nerve fibers, dendritic cells and to measure tear film parameters in migraine.87 eyes of 44 patients suffering from migraine with a mean age of 33.23 ± 11.41 years were included in our study. 25 age-matched controls (mean age of 30.16 ± 12.59 years; P = 0.162) were recruited. The corneal subbasal plexus and the dendritic cells (DC) were analyzed using in vivo confocal microscopy (Heidelberg Retina Tomograph II Rostock Cornea Module; Heidelberg Engineering GmbH), and the tear film was imaged using LacryDiag (Quantel Medical, France).Regarding the subbasal nerve fibers of the cornea, none of the examined parameters differed significantly in migraine patients from controls. We found a significant increase in the corneal DC density (P < 0.0001) and DC area (P < 0.0001) in migraine patients compared to healthy volunteers. DC density showed a positive correlation with the monthly attack frequency (r = 0.32, P = 0.041) and the DC area a negative correlation with corneal nerve branch density (r = -0.233, P = 0.039), nerve fiber length (r = -0.232, P = 0.04) and total branch density (r = -0.233, P = 0.039). Using LacryDiag a significant loss of Meibomian gland area could be detected on the superior eyelid (P = 0.005) in migraine.Our results suggest the presence of neuroinflammation in the cornea of migraine patients affecting the peripheral trigeminal system. Dendritic cells surrounding the subbasal plexus may be involved in the activation and modulation of pain in migraine.},
	keywords = {MIGRAINE; Dendritic cell; Cornea; Corneal nerves; In vivo corneal confocal microscopy},
	year = {2024},
	eissn = {1435-702X},
	pages = {1591-1598},
	orcid-numbers = {Tóth, Noémi/0000-0003-4210-0774; Szalai, Eszter/0000-0002-6723-0914}
}

@article{MTMT:34207248,
	title = {The volume of the thalamus and hippocampus in a right-handed female episodic migraine group},
	url = {https://m2.mtmt.hu/api/publication/34207248},
	author = {He, Mingchen and Kis-Jakab, Gréta and Komáromy, Hedvig and Perlaki, Gábor and Orsi, Gergely and Bosnyák, Edit and Rozgonyi, Renáta and John, Flóra and Trauninger, Anita and Eklicsné Lepenye, Katalin and Pfund, Zoltán},
	doi = {10.3389/fneur.2023.1254628},
	journal-iso = {FRONT NEUR},
	journal = {FRONTIERS IN NEUROLOGY},
	volume = {14},
	unique-id = {34207248},
	issn = {1664-2295},
	year = {2023},
	eissn = {1664-2295}
}

@article{MTMT:32797860,
	title = {The Impact of Diabetes Mellitus and Admission Hyperglycemia on Clinical Outcomes after Recanalization Therapies for Acute Ischemic Stroke: STAY ALIVE National Prospective Registry},
	url = {https://m2.mtmt.hu/api/publication/32797860},
	author = {Kalmár, Péter János and Tárkányi, Gábor and Karadi, Zsofia Nozomi and Szapáry, László and Bosnyák, Edit},
	doi = {10.3390/life12050632},
	journal-iso = {LIFE-BASEL},
	journal = {LIFE-BASEL},
	volume = {12},
	unique-id = {32797860},
	year = {2022},
	eissn = {2075-1729}
}

@article{MTMT:32647101,
	title = {A mechanikus thrombectomiát megelőző intravénás thrombolysis szerepe az akut agyi nagyérelzáródások kezelésében},
	url = {https://m2.mtmt.hu/api/publication/32647101},
	author = {Kalmár, Péter János and Tárkányi, Gábor and Karádi, Nozomi Zsófia and Bosnyák, Edit and Nagy, Csaba Balázs and Csécsei, Péter and Lenzsér, Gábor and Büki, András and Janszky, József Vladimír and Szapáry, László},
	doi = {10.18071/isz.75.0023},
	journal-iso = {IDEGGYOGY SZEMLE},
	journal = {IDEGGYOGYASZATI SZEMLE / CLINICAL NEUROSCIENCE},
	volume = {75},
	unique-id = {32647101},
	issn = {0019-1442},
	abstract = {The efficacy of intravenous thrombolysis (IVT) is moderate in the proximal vascular segments of intracranial arteries, as opposed to mecha-nical thrombectomy (MT). In the management of acute ischemic stroke (AIS) caused by large vessel occlusions (LVO), IVT prior to MT is highly recommended based on the latest guidelines, but the necessity of IVT has been questioned by the latest studies of the past years. The aim of our study was to investigate and compare the efficacy and safety of direct mechanical thrombectomy (dMT) and combined therapy (CT) for patients who suffered an AIS with LVO and were treated in our department.We investigated patients with AIS caused by LVO who were admitted up to 4.5 hours after symptom onset and underwent MT in our department between November 2017 and August 2019. Patients' data were collected in our stroke register. Patients enrolled in our study were divided into two groups depending on whether dMT or CT was used. Our primary outcome was the 30- and 90- day functional outcome measured by modified Rankin Scale (mRS). Mortality at 30- and 90- day, successful recanalization rates, and symptomatic intracranial hemorrhage were considered as secondary outcomes.A total of 142 patients (age: 68.3 ± 12.6 years, 53.5% female) were enrolled in our study, including 81 (57.0%) dMT cases, and 61 (43.0%) patients who received CT. The vascular risk factors and comorbidities were significantly higher in the dMT-treated group. At day 30, the rate of favorable functional outcomes was 34.7% in dMT vs. 43.6% among those who received CT (p = 0.307), by day 90 this ratio changed to 40.8% vs. 46.3% (p = 0.542). Mortality rates at day 30 were 22.2% and 23.6% (p = 0.851), and at day 90 33.8% and 25.9% (p = 0.343). The rate of effective recanalization was 94.2% for dMT-treated patients and 98.0% for CT-treated patients (p = 0.318). Symptomatic intracranial hemorrhage was detected in 2.5% of dMT-treated patients and 3.4% of CT-treated group (p = 0.757).Our results suggest that CT is associated with a moderately better outcome compared to dMT. IVT prior to MT did not increase the risk of symptomatic intracranial hemorrhages.},
	keywords = {thrombolysis; stroke; Thrombectomy; Ischaemia},
	year = {2022},
	eissn = {2498-6208},
	pages = {23-29},
	orcid-numbers = {Janszky, József Vladimír/0000-0001-6100-832X}
}

@article{MTMT:32213190,
	title = {Biztonságos az intravénás thrombolysis mély agyi stimulációval kezelt betegeknél?},
	url = {https://m2.mtmt.hu/api/publication/32213190},
	author = {Pintér, Dávid and Balás, István and Szapáry, László and Bosnyák, Edit and Makó, Tamás and Juhász, Annamária and Janszky, József Vladimír and Kovács, Norbert},
	journal-iso = {IDEGGYÓGY SZEMLE PROC},
	journal = {IDEGGYÓGYÁSZATI SZEMLE PROCEEDINGS / CLINICAL NEUROSCIENCE PROCEEDINGS},
	volume = {6},
	unique-id = {32213190},
	issn = {2498-6240},
	year = {2021},
	pages = {38-38},
	orcid-numbers = {Makó, Tamás/0000-0002-9865-8761; Janszky, József Vladimír/0000-0001-6100-832X; Kovács, Norbert/0000-0002-7332-9240}
}

@misc{MTMT:32213188,
	title = {Biztonságos az intravénás thrombolysis mély agyi stimulációval kezelt betegeknél?},
	url = {https://m2.mtmt.hu/api/publication/32213188},
	author = {Pintér, Dávid and Balás, István and Szapáry, László and Bosnyák, Edit and Makó, Tamás and Juhász, Annamária and Janszky, József Vladimír and Kovács, Norbert},
	unique-id = {32213188},
	year = {2021},
	orcid-numbers = {Makó, Tamás/0000-0002-9865-8761; Janszky, József Vladimír/0000-0001-6100-832X; Kovács, Norbert/0000-0002-7332-9240}
}

@article{MTMT:32029068,
	title = {Comparing Endovascular Treatment Methods in Acute Ischemic Stroke Due to Tandem Occlusion Focusing on Clinical Aspects},
	url = {https://m2.mtmt.hu/api/publication/32029068},
	author = {Kalmár, Péter János and Tárkányi, Gábor and Nagy, Csaba Balázs and Csécsei, Péter and Lenzsér, Gábor and Bosnyák, Edit and Karadi, Zsofia Nozomi and Annus, Ádám and Szegedi, István and Büki, András and Szapáry, László},
	doi = {10.3390/life11050458},
	journal-iso = {LIFE-BASEL},
	journal = {LIFE-BASEL},
	volume = {11},
	unique-id = {32029068},
	year = {2021},
	eissn = {2075-1729},
	orcid-numbers = {Annus, Ádám/0000-0003-0498-6578; Szegedi, István/0000-0003-4181-4361}
}

@article{MTMT:31953048,
	title = {Capability of stroke scales to detect large vessel occlusion in acute ischemic stroke : A pilot study},
	url = {https://m2.mtmt.hu/api/publication/31953048},
	author = {Tárkányi, Gábor and Karádi, Zsófia Nozomi and Csécsei, Péter and Bosnyák, Edit and Fehér, Gergely and Molnár, Tihamér and Szapáry, László},
	doi = {10.18071/isz.74.0099},
	journal-iso = {IDEGGYOGY SZEMLE},
	journal = {IDEGGYOGYASZATI SZEMLE / CLINICAL NEUROSCIENCE},
	volume = {74},
	unique-id = {31953048},
	issn = {0019-1442},
	abstract = {Az elmúlt évek változásai a stroke-ellátásban szükségessé teszik pontos és könnyen használható módszerek kifejlesztését nagyérelzáródás (NÉO) detektá­lására akut ischaemiás stroke-ban (AIS). Kutatásunk célja számos stroke-skála NÉO detektálására való alkal­mas­sá­gának vizsgálata AIS-betegek esetében. Egy hazai stroke-regiszteren alapuló kereszt­metszeti vizsgálatot végeztünk, melybe olyan bete­ge­ket vontunk be, akik első AIS-jukat szenvedték el, és 4,5 órán belül felvételre kerültek egy komprehenzív stroke-centrumba. Összesen 14 stroke-skála diagnosztikus képességét vizsgáltuk receiver operating characteristic (ROC) analízis segítségével. A ROC-görbe alatti terület az NIHSS, modified NIHSS, shortened NIHSS-EMS, sNIHSS-8, sNIHSS-5 és Rapid Arterial Occlusion Evaluation (RACE) skálák esetében volt a legmagasabb (>0,800 mindegyik esetben). Összesen hat skála esetében találtunk olyan küszöbértéket, amellyel legalább 80%-os szenzitivitás (SN) és 50%-os specificitás (SP) volt elérhető. Olyan küszöb­értéket, amely legalább 70%-os SN-t és 75%-os SP-t biztosított, öt skála esetében találtunk. Több stroke-skála is alkalmas lehet NÉO detektálására AIS-ban. Az NIHSS és a modified NIHSS elsősorban kórházi felhasználásra alkalmas. Mivel azonban a sNIHSS-EMS, sNIHSS-8, sNIHSS-5, RACE és 3 Item Stroke Scale (3I-SS) skálák rövidebbek és egyszerűbb a felvételük, alkalmazásuk akár prehospitális körülmények között is kivitelezhető lehet. További vizsgálatok szükségesek ezen skálák prospektív (prehospitális) validálásának céljából.},
	keywords = {ischaemiás stroke; akut stroke; nagyérelzáródás; stroke-skála},
	year = {2021},
	eissn = {2498-6208},
	pages = {99-103}
}

@article{MTMT:31312171,
	title = {Risk analysis of post-procedural intracranial hemorrhage based on STAY ALIVE Acute Stroke Registry},
	url = {https://m2.mtmt.hu/api/publication/31312171},
	author = {Csécsei, Péter and Tárkányi, Gábor and Bosnyák, Edit and Szapáry, László and Lenzsér, Gábor and Szolics, Alex and Büki, András and Hegyi, Péter and Abada, Alan and Molnár, Tihamér},
	doi = {10.1016/j.jstrokecerebrovasdis.2020.104851},
	journal-iso = {J STROKE CEREBROVASC DIS},
	journal = {JOURNAL OF STROKE AND CEREBROVASCULAR DISEASES},
	volume = {29},
	unique-id = {31312171},
	issn = {1052-3057},
	year = {2020},
	eissn = {1532-8511},
	orcid-numbers = {Tárkányi, Gábor/0000-0003-3584-1152; Hegyi, Péter/0000-0003-0399-7259; Abada, Alan/0000-0002-6047-4764}
}