@mastersthesis{MTMT:34115677,
	title = {Preparation of bioactive oxidized hydroxycinnamic acid derivatives [Bioaktív oxidált hidroxifahéjsav-származékok előállítása]},
	url = {https://m2.mtmt.hu/api/publication/34115677},
	author = {Fási, Laura},
	doi = {10.14232/phd.10852},
	publisher = {Universití of Szeged},
	unique-id = {34115677},
	year = {2022}
}

@article{MTMT:31657056,
	title = {AAPH or Peroxynitrite-Induced Biorelevant Oxidation of Methyl Caffeate Yields a Potent Antitumor Metabolite},
	url = {https://m2.mtmt.hu/api/publication/31657056},
	author = {Fási, Laura and Latif, Ahmed Dhahir and Zupkó, István and Sándor, Lévai and Dékány, Miklós and Béni, Zoltán and Árpád, Könczöl and Balogh, György Tibor and Hunyadi, Attila},
	doi = {10.3390/biom10111537},
	journal-iso = {BIOMOLECULES},
	journal = {BIOMOLECULES},
	volume = {10},
	unique-id = {31657056},
	issn = {2218-273X},
	year = {2020},
	eissn = {2218-273X},
	orcid-numbers = {Zupkó, István/0000-0003-3243-5300; Béni, Zoltán/0000-0002-1275-4155; Balogh, György Tibor/0000-0003-3347-1880; Hunyadi, Attila/0000-0003-0074-3472}
}

@CONFERENCE{MTMT:31192702,
	title = {Natural product inspired chemical approaches against MDR cancer},
	url = {https://m2.mtmt.hu/api/publication/31192702},
	author = {Fási, Laura and Vágvölgyi, Máté and Latif, Ahmed Dhahir and Issaadi, Halima Meriem and Zoofishan, Zoofishan and Zupkó, István and Spengler, Gabriella and Martins, Ana and Hunyadi, Attila},
	booktitle = {New Diagnostic and Therapeutic Tools against Multidrug-Resistant Tumours},
	unique-id = {31192702},
	year = {2019},
	pages = {12-13},
	orcid-numbers = {Vágvölgyi, Máté/0000-0002-2233-9422; Zupkó, István/0000-0003-3243-5300; Spengler, Gabriella/0000-0001-8085-0950; Hunyadi, Attila/0000-0003-0074-3472}
}

@article{MTMT:30380633,
	title = {Antioxidant-inspired drug discovery: antitumor metabolite is formed in situ from a hydroxycinnamic acid derivative upon free radical scavenging},
	url = {https://m2.mtmt.hu/api/publication/30380633},
	author = {Fási, Laura and Di Meo, Florent and Kuo, Ching-Ying and Stojkovic Buric, Sonja and Martins, Ana and Kúsz, Norbert and Béni, Zoltán and Dékány, Miklós and Balogh, György Tibor and Pesic, Milica and Wang, Hui-Chun and Trouillas, Patrick and Hunyadi, Attila},
	doi = {10.1021/acs.jmedchem.8b01994},
	journal-iso = {J MED CHEM},
	journal = {JOURNAL OF MEDICINAL CHEMISTRY},
	volume = {62},
	unique-id = {30380633},
	issn = {0022-2623},
	abstract = {Cancer cells generally possess higher levels of reactive oxygen species than normal cells, and this can serve as a possible therapeutic target. In this proof-of-concept study, an antioxidant-inspired drug discovery strategy was evaluated using a hydroxycinnamic acid derivative. The processing of oxidized mixtures of p-coumaric acid methyl ester (pcm) revealed a new antitumor lead, graviquinone. Graviquinone bypassed ABCB1-mediated resistance, induced DNA damage in lung carcinoma cells but exerted DNA protective activity in normal keratinocytes, and modulated DNA damage response in MCF-7 cells. The cytotoxic effect of pcm in MCF-7 cells was potentiated under H2O2-induced oxidative stress, and the formation of graviquinone was confirmed by Fenton's reaction on pcm. In silico density functional theory calculations suggested graviquinone as a kinetic product of pcm-scavenging (OH)-O-center dot radicals. Our results demonstrate the pharmacological value of an in situ-formed, oxidative stress-related metabolite of an antioxidant. This might be of particular importance for designing new strategies for antioxidant-based drug discovery.},
	year = {2019},
	eissn = {1520-4804},
	pages = {1657-1668},
	orcid-numbers = {Kúsz, Norbert/0000-0002-9973-6442; Béni, Zoltán/0000-0002-1275-4155; Balogh, György Tibor/0000-0003-3347-1880; Hunyadi, Attila/0000-0003-0074-3472}
}

@CONFERENCE{MTMT:3426792,
	title = {Semi-synthetic preparation of antitumor p-coumaric acid derivatives},
	url = {https://m2.mtmt.hu/api/publication/3426792},
	author = {Fási, Laura and Gyovai, András and Zupkó, István and Nové, Márta and Spengler, Gabriella and Fang-Rong, Chang and Hunyadi, Attila},
	booktitle = {GA2018: The 66th Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA); S-TCM 2018 : The 11th Shanghai International Conference on Traditional Chinese Medicine and Natural Medicine},
	unique-id = {3426792},
	year = {2018},
	orcid-numbers = {Gyovai, András/0000-0003-2316-2160; Zupkó, István/0000-0003-3243-5300; Spengler, Gabriella/0000-0001-8085-0950; Hunyadi, Attila/0000-0003-0074-3472}
}

@article{MTMT:3347203,
	title = {Anti-inflammatory Activity of Melampyrum barbatum and Isolation of Iridoid and Flavonoid Compounds},
	url = {https://m2.mtmt.hu/api/publication/3347203},
	author = {Háznagyné Radnai, Erzsébet and Fási, Laura and Wéber, Edit and Pinke, Gyula and Király, Botond Gergely and Sztojkov-Ivanov, Anita and Gáspár, Róbert and Hohmann, Judit},
	doi = {10.1177/1934578x1801300301},
	journal-iso = {NAT PROD COMMUN},
	journal = {NATURAL PRODUCT COMMUNICATIONS},
	volume = {13},
	unique-id = {3347203},
	issn = {1934-578X},
	abstract = {Melampyrum barbatum Waldst. & Kit. ex Willd. (Scrophulariaceae) has been used in traditional medicine for the treatment of rheumatic complaints and different skin diseases. In the course of our study the anti-inflammatory activity of the aerial parts of M barbatum was evaluated. A MeOH extract was prepared and consecutively partitioned with CHCl3, EtOAc and n-BuOH. The fractions were assayed in in vivo carrageenan-induced rat paw oedema model. The intraperitoneally administered n-BuOH phase exerted marked inhibitory effect (33.6 %, p < 0.01). Multistep chromatographic separation afforded mussaenoside and aucubine from n-BuOH fraction. Moreover, 8-epiloganin, loganic acid and mussaenoside were obtained from EtOAc fraction and apigenin, luteolin, benzoic acid and galactitol from CHCl3 fraction. These data validate the ethnomedicinal use of M barbatum for the treatment of inflammatory diseases and reveal that iridoids and flavonoids could be responsible for the anti-inflammatory effect of this species.},
	keywords = {Flavonoids; IRIDOIDS; anti-inflammatory activity; Melampyrum barbatum; Scrophulariaceae},
	year = {2018},
	eissn = {1555-9475},
	pages = {235-236},
	orcid-numbers = {Háznagyné Radnai, Erzsébet/0000-0003-4034-5989; Wéber, Edit/0000-0002-5904-0619; Pinke, Gyula/0000-0002-9956-1363; Király, Botond Gergely/0000-0002-8439-2616; Gáspár, Róbert/0000-0002-1571-7579; Hohmann, Judit/0000-0002-2887-6392}
}

@misc{MTMT:3141373,
	title = {Az emésztés, valamint a bél- és májműködés támogatása},
	url = {https://m2.mtmt.hu/api/publication/3141373},
	author = {Fási, Laura},
	unique-id = {3141373},
	year = {2016},
	pages = {16-17}
}

@article{MTMT:3133476,
	title = {Cephalotaxus harringtonia − homoharringtonin},
	url = {https://m2.mtmt.hu/api/publication/3133476},
	author = {Fási, Laura and Hunyadi, Attila},
	journal-iso = {GYÓGYSZERÉSZET},
	journal = {GYÓGYSZERÉSZET},
	volume = {60},
	unique-id = {3133476},
	issn = {0017-6036},
	year = {2016},
	pages = {469-471},
	orcid-numbers = {Hunyadi, Attila/0000-0003-0074-3472}
}

@CONFERENCE{MTMT:3082840,
	title = {A p-kumársav-metilészter antitumor hatású oxidált származékainak előállítása},
	url = {https://m2.mtmt.hu/api/publication/3082840},
	author = {Fási, Laura and Martins, Ana and Kúsz, Norbert and Fődi, Tamás and Ignácz, Gergő and Béni, Zoltán and Balogh, György Tibor and Hunyadi, Attila},
	booktitle = {Fiatal Gyógynövénykutatók Fóruma: a Magyar Gyógyszerésztudományi Társaság Gyógynövény Szakosztályának tudományos konferenciája},
	unique-id = {3082840},
	year = {2016},
	pages = {10-10},
	orcid-numbers = {Kúsz, Norbert/0000-0002-9973-6442; Béni, Zoltán/0000-0002-1275-4155; Balogh, György Tibor/0000-0003-3347-1880; Hunyadi, Attila/0000-0003-0074-3472}
}

@CONFERENCE{MTMT:3054546,
	title = {What we can provide for collaboration: an overview of our available compound library},
	url = {https://m2.mtmt.hu/api/publication/3054546},
	author = {Hunyadi, Attila and Dankó, Balázs Ödön and Csábi, József and Vágvölgyi, Máté and Issaadi, Halima Meriem and Fási, Laura and Zoofishan, Zoofishan},
	booktitle = {2nd meeting of COST Action CM1407},
	unique-id = {3054546},
	year = {2016},
	pages = {37-38},
	orcid-numbers = {Hunyadi, Attila/0000-0003-0074-3472; Vágvölgyi, Máté/0000-0002-2233-9422}
}