@article{MTMT:32242113, title = {Protective effects of PACAP in a rat model of diabetic neuropathy}, url = {https://m2.mtmt.hu/api/publication/32242113}, author = {Kiss, Péter and Bánki, Eszter Márta and Gaszner, Balázs and Nagy, Daniel and Helyes, Zsuzsanna and Pál, Endre and Rémán, Gyöngyvér Éva and Tóth, Gábor and Tamás, Andrea and Reglődi, Dóra}, doi = {10.3390/ijms221910691}, journal-iso = {INT J MOL SCI}, journal = {INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES}, volume = {22}, unique-id = {32242113}, issn = {1661-6596}, year = {2021}, eissn = {1422-0067}, orcid-numbers = {Gaszner, Balázs/0000-0003-2830-2732; Tóth, Gábor/0000-0002-3604-4385} } @article{MTMT:3320609, title = {Effects of Pituitary Adenylate Cyclase Activating Polypeptide in Human Proximal Tubule Cells Against Gentamicin Toxicity}, url = {https://m2.mtmt.hu/api/publication/3320609}, author = {Horváth-Opper, Gabriella and Reglődi, Dóra and Czétány, Péter and Illés, Anita and Rémán, Gyöngyvér Éva and Fekete, Andrea and Tóth, Gábor and László, Eszter and Opper, Balázs}, doi = {10.1007/s10989-017-9666-5}, journal-iso = {INT J PEPT RES THER}, journal = {INTERNATIONAL JOURNAL OF PEPTIDE RESEARCH AND THERAPEUTICS}, volume = {25}, unique-id = {3320609}, issn = {1573-3149}, year = {2019}, eissn = {1573-3904}, pages = {257-264}, orcid-numbers = {Fekete, Andrea/0000-0002-0210-153X; Tóth, Gábor/0000-0002-3604-4385} } @article{MTMT:3339992, title = {Pituitary adenylate cyclase-activating polypeptide ameliorates vascular dysfunction induced by hyperglycaemia}, url = {https://m2.mtmt.hu/api/publication/3339992}, author = {Varjú-Solymár, Margit and Ivic, Ivan and Balaskó, Márta and Fülöp, Balázs Dániel and Tóth, Gábor and Tamás, Andrea and Rémán, Gyöngyvér Éva and Koller, Ákos and Reglődi, Dóra}, doi = {10.1177/1479164118757922}, journal-iso = {DIABETES VASC DIS RES}, journal = {DIABETES & VASCULAR DISEASE RESEARCH}, volume = {15}, unique-id = {3339992}, issn = {1479-1641}, abstract = {BACKGROUND: Short-lasting hyperglycaemia occurs frequently in prediabetes and poorly controlled diabetes mellitus leading to vascular damage. Pituitary adenylate cyclase-activating polypeptide (PACAP) has been shown to play a protective role in vascular complications of diabetes; moreover, antioxidant effects of PACAP were also described. Therefore, we hypothesized that PACAP exerts protective effects in short-term hyperglycaemia-induced vascular dysfunctions. METHODS: After short-term hyperglycaemia, acetylcholine-induced and sodium nitroprusside-induced vascular relaxation of mouse carotid arteries were tested with a myograph with or without the presence of PACAP or superoxide dismutase. Potential direct antioxidant superoxide-scavenging action of pituitary adenylate cyclase-activating peptide was tested with pyrogallol autoxidation assay; furthermore, the effect of pituitary adenylate cyclase-activating peptide or superoxide dismutase was investigated on hyperglycaemia-associated vascular markers. RESULTS: PACAP administration resulted in reduced endothelial dysfunction after a 1-h hyperglycaemic episode. PACAP was able to restore acetylcholine-induced relaxation of the vessels and improved sodium nitroprusside-induced relaxation. This effect was comparable to the protective effect of superoxide dismutase, but PACAP was unable to directly scavenge superoxide produced by autoxidation of pyrogallol. Endothelial dysfunction was associated with elevated levels of fibroblast growth factor basic, matrix metalloproteinase 9 and nephroblastoma overexpressed gene proteins. Their release was reduced by PACAP administration. CONCLUSION: These results suggest a strong protective role of PACAP in the vascular complications of diabetes.}, year = {2018}, eissn = {1752-8984}, pages = {277-285}, orcid-numbers = {Varjú-Solymár, Margit/0000-0001-6667-6263; Tóth, Gábor/0000-0002-3604-4385; Koller, Ákos/0000-0003-3256-8701} } @article{MTMT:2523801, title = {Examination of PACAP-like immunoreactivity in different pathological clinical samples}, url = {https://m2.mtmt.hu/api/publication/2523801}, author = {Tamás, Andrea and Jávorházy, András and Csanaky, Katalin and Ragnhildstveit, E and Vikjord, SA and Sarlos, PD and Sárszegi, Zsolt and Zapf, I and Szántó, Z and Faludi, B and Molnár, T and Németh, J and Bánki, E and Lelesz, B and Rémán, Gyöngyvér Éva and Reglődi, Dóra}, journal-iso = {J MOL NEUROSCI}, journal = {JOURNAL OF MOLECULAR NEUROSCIENCE}, volume = {51}, unique-id = {2523801}, issn = {0895-8696}, year = {2013}, eissn = {1559-1166}, pages = {207-208} }