TY - JOUR AU - Pedersen, M AU - Mendez, MA AU - Schoket, B AU - Godschalk, RW AU - Espinosa, A AU - Landstrom, A AU - Villanueva, CM AU - Merlo, DF AU - Fthenou, E AU - Gracia-Lavedan, E AU - van Schooten, FJ AU - Hoek, G AU - Brunborg, G AU - Meltzer, HM AU - Alexander, J AU - Nielsen, JK AU - Sunyer, J AU - Wright, J AU - Kovacs, K AU - de Hoogh, K AU - Gutzkow, KB AU - Hardie, LJ AU - Chatzi, L AU - Knudsen, LE AU - Anna, L AU - Ketzel, M AU - Haugen, M AU - Botsivali, M AU - Nieuwenhuijsen, MJ AU - Cirach, M AU - Toledano, MB AU - Smith, RB AU - Fleming, S AU - Agramunt, S AU - Kyrtopoulos, SA AU - Lukács, Viktória Alexa AU - Kleinjans, JC AU - Segerback, D AU - Kogevinas, M TI - Environmental, Dietary, Maternal, and Fetal Predictors of Bulky DNA Adducts in Cord Blood: A European Mother-Child Study (NewGeneris) JF - ENVIRONMENTAL HEALTH PERSPECTIVES J2 - ENVIRON HEALTH PERSP VL - 123 PY - 2015 IS - 4 SP - 374 EP - 380 PG - 7 SN - 0091-6765 DO - 10.1289/ehp.1408613 UR - https://m2.mtmt.hu/api/publication/3221007 ID - 3221007 N1 - Megjegyzés-24734048 : John/H-1624-2012 AB - Background: Bulky DNA adducts reflect genotoxic exposures, have been associated with lower birth weight, and may predict cancer risk. Objective: We selected factors known or hypothesized to affect in utero adduct formation and repair and examined their associations with adduct levels in neonates. Methods: Pregnant women from Greece, Spain, England, Denmark, and Norway were recruited in 2006-2010. Cord blood bulky DNA adduct levels were measured by the P-32-postlabeling technique (n = 511). Diet and maternal characteristics were assessed via questionnaires. Modeled exposures to air pollutants and drinking-water disinfection by-products, mainly trihalomethanes (THMs), were available for a large proportion of the study population. Results: Greek and Spanish neonates had higher adduct levels than the northern European neonates [median, 12.1 (n = 179) vs. 6.8 (n = 332) adducts per 108 nucleotides, p < 0.001]. Residence in southern European countries, higher maternal body mass index, delivery by cesarean section, male infant sex, low maternal intake of fruits rich in vitamin C, high intake of dairy products, and low adherence to healthy diet score were statistically significantly associated with higher adduct levels in adjusted models. Exposure to fine particulate matter and nitrogen dioxide was associated with significantly higher adducts in the Danish subsample only. Overall, the pooled results for THMs in water show no evidence of association with adduct levels; however, there are country-specific differences in results with a suggestion of an association in England. Conclusion: These findings suggest that a combination of factors, including unknown country-specific factors, influence the bulky DNA adduct levels in neonates. LA - English DB - MTMT ER - TY - JOUR AU - Pedersen, M AU - Schoket, B AU - Godschalk, RW AU - Wright, J AU - von Stedingk, H AU - Tornqvist, M AU - Sunyer, J AU - Nielsen, JK AU - Merlo, DF AU - Mendez, MA AU - Meltzer, HM AU - Lukács, Viktória Alexa AU - Landstrom, A AU - Kyrtopoulos, SA AU - Kovacs, K AU - Knudsen, LE AU - Haugen, M AU - Hardie, LJ AU - Gutzkow, KB AU - Fleming, S AU - Fthenou, E AU - Farmer, PB AU - Espinosa, A AU - Chatzi, L AU - Brunborg, G AU - Brady, NJ AU - Botsivali, M AU - Arab, K AU - Anna, L AU - Alexander, J AU - Agramunt, S AU - Kleinjans, JC AU - Segerback, D AU - Kogevinas, M TI - Bulky DNA adducts in cord blood, maternal fruit-and-vegetable consumption, and birth weight in a European mother-child study JF - ENVIRONMENTAL HEALTH PERSPECTIVES J2 - ENVIRON HEALTH PERSP VL - 121 PY - 2013 IS - 10 SP - 1200 EP - 1206 PG - 7 SN - 0091-6765 DO - 10.1289/ehp.1206333 UR - https://m2.mtmt.hu/api/publication/2891684 ID - 2891684 LA - English DB - MTMT ER - TY - JOUR AU - Pedersen, Marie AU - Schoket, Bernadette AU - Godschalk, Roger AU - Mendez, Michelle A AU - Knudsen, Lisbeth E AU - Gutzkow, Kristine B AU - Fleming, Sarah AU - Chatzi, Leda AU - Agramunt, Silvia AU - Anna, Lívia AU - Kovács, Katalin AU - Lukács, Viktória Alexa AU - Merlo, Domenico F AU - Kleinjans, Jos C AU - Segerbäck, Dan AU - Kogevinas, Manolis AU - on, behalf of the NewGeneris study group (EU Contract no FOOD-CT-2005-016320) TI - O-012: Bulky DNA Adducts in Cord Blood, Maternal Diet and Birth Weight in a European Prospective Mother-Child Study (NEWGENERIS). JF - EPIDEMIOLOGY J2 - EPIDEMIOLOGY VL - 23 PY - 2012 IS - 5S SN - 1044-3983 DO - 10.1097/01.ede.0000416670.90099.80 UR - https://m2.mtmt.hu/api/publication/2891678 ID - 2891678 LA - English DB - MTMT ER - TY - JOUR AU - Halász, László AU - Lukács, Viktória Alexa TI - Idegmérgek késői hatásai JF - HADMÉRNÖK J2 - HADMÉRNÖK VL - 7 PY - 2012 IS - 3 SP - 50 EP - 59 PG - 10 SN - 1788-1919 UR - https://m2.mtmt.hu/api/publication/2141516 ID - 2141516 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Anna, L AU - Kovács, K AU - Lukács, Viktória Alexa AU - Győrffy, E AU - Rudnai, P AU - Schoket, B TI - Assessment of exposure to polycyclic aromatic hydrocarbons during pregnancy with bulky DNA adduct biomarker in European mother - child cohorts JF - MUTAGENESIS J2 - MUTAGENESIS VL - 26 PY - 2011 IS - 5 SP - 713 SN - 0267-8357 UR - https://m2.mtmt.hu/api/publication/2892875 ID - 2892875 LA - English DB - MTMT ER - TY - JOUR AU - Braun, Mihály AU - Papp, István AU - Korponai, János AU - Lukács, Viktória Alexa AU - Gyulai, István AU - Forró, László AU - Hubay, Katalin AU - Szalóki, Imre TI - A Tisza vízjárásának nyomai a Marótzugi-Holt-Tisza üledékében JF - HIDROLÓGIAI KÖZLÖNY J2 - HIDROL KOZL VL - 90 PY - 2010 IS - 6 SP - 20 EP - 22 PG - 3 SN - 0018-1323 UR - https://m2.mtmt.hu/api/publication/1802899 ID - 1802899 N1 - LI. Hidrobiológus Napok, "Új módszerek és eljárások a hidrobiológiában", Tihany, 2009. szeptember 30- október 2. LA - Hungarian DB - MTMT ER - TY - THES AU - Lukács, Viktória Alexa TI - A nád (Phragmites Australis) genetikai diverzitásának vizsgálata PCR-RAPD technikával = Genetic diversity of the reed (Phragmites Australis) studied by PCR-RAPD method PB - Corvinus University of Budapest PY - 2009 SP - 110 UR - https://m2.mtmt.hu/api/publication/2891681 ID - 2891681 LA - Hungarian DB - MTMT ER - TY - CHAP AU - Herodek, Sándor AU - Tóth, Viktor R. AU - Zlinszky, András AU - Lukács, Viktória Alexa TI - Mitől pusztulnak a nádasok? T2 - Balaton-kutatásról mindenkinek PB - MTA Balatoni Limnológiai Kutatóintézet CY - Tihany SN - 9789630678285 PY - 2009 SP - 155 EP - 168 PG - 14 UR - https://m2.mtmt.hu/api/publication/122843 ID - 122843 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Lukács, Viktória Alexa AU - Bisztray, György Dénes AU - Herodek, Sándor TI - A Fertő és a Kis-Balaton nádasainak genetikai diverzitása JF - HIDROLÓGIAI KÖZLÖNY J2 - HIDROL KOZL VL - 89 PY - 2009 IS - 6 SP - 36 EP - 38 PG - 3 SN - 0018-1323 UR - https://m2.mtmt.hu/api/publication/122837 ID - 122837 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Lukács, Viktória Alexa AU - Bisztray, György Dénes AU - Herodek, Sándor TI - A Bodeni-tó, az Osterseen és a Mondsee nádasainak genetikai diverzitása JF - KERTGAZDASÁG (1998) J2 - KERTGAZDASÁG (1998) VL - 41 PY - 2009 IS - 1 SP - 59 EP - 64 PG - 6 SN - 1419-2713 UR - https://m2.mtmt.hu/api/publication/122836 ID - 122836 LA - Hungarian DB - MTMT ER -