@mastersthesis{MTMT:2921417,
	title = {Effect of endurance exercise alone and in combination with IGF-1 administration on cellular markers involved in sarcopenia},
	url = {https://m2.mtmt.hu/api/publication/2921417},
	author = {Mosaferi Ziaaldini, Mohammad},
	doi = {10.17624/TF.2015.02},
	unique-id = {2921417},
	year = {2015}
}

@article{MTMT:2883904,
	title = {Exercise training increases anabolic and attenuates catabolic and apoptotic processes in aged skeletal muscle of male rats},
	url = {https://m2.mtmt.hu/api/publication/2883904},
	author = {Mosaferi Ziaaldini, Mohammad and Koltai, Erika and Csende, Zsolt and Goto, Sataro and Boldogh, Istvan and Taylor, Albert W and Radák, Zsolt},
	doi = {10.1016/j.exger.2015.04.008},
	journal-iso = {EXP GERONTOL},
	journal = {EXPERIMENTAL GERONTOLOGY},
	volume = {67},
	unique-id = {2883904},
	issn = {0531-5565},
	abstract = {Abstract Aging results in significant loss of mass and function of the skeletal muscle, which negatively impacts the quality of life. In this study we investigated whether aerobic exercise training has the potential to alter anabolic and catabolic pathways in the skeletal muscle. Five and twenty eight month old rats were used in the study. Aging resulted in decreased levels of follistatin/mTOR/Akt/Erk activation and increased myostatin/Murf1/2, proteasome subunits, and protein ubiquitination levels. In addition, TNF-α, reactive oxygen species (ROS), p53, and Bax levels were increased while Bcl-2 levels were decreased in the skeletal muscle of aged rats. Six weeks of exercise training at 60% of VO2max reversed the age-associated activation of catabolic and apoptotic pathways and increased anabolic signaling. The results suggest that the age-associated loss of muscle mass and cachexia could be due to the orchestrated down-regulation of anabolic and up-regulation of catabolic and pro-apoptotic processes. These metabolic changes can be attenuated by exercise training.},
	keywords = {FOLLISTATIN; MYOSTATIN; skeletal muscle; Aging; Exercise; Reactive oxygen species},
	year = {2015},
	eissn = {1873-6815},
	pages = {9-14},
	orcid-numbers = {Koltai, Erika/0000-0002-1370-2955; Radák, Zsolt/0000-0003-1297-6804}
}

@article{MTMT:2796664,
	title = {Exercise increases markers of spermatogenesis in rats selectively bred for low running capacity},
	url = {https://m2.mtmt.hu/api/publication/2796664},
	author = {Torma, Ferenc Gergely and Koltai, Erika and Nagy, E and Mosaferi Ziaaldini, Mohammad and Pósa, Anikó and Koch, LG and Britton, SL and Boldogh, I and Radák, Zsolt},
	doi = {10.1371/journal.pone.0114075},
	journal-iso = {PLOS ONE},
	journal = {PLOS ONE},
	volume = {9},
	unique-id = {2796664},
	issn = {1932-6203},
	abstract = {The oxidative stress effect of exercise training on testis function is under debate. In the present study we used a unique rat model system developed by artificial selection for low and high intrinsic running capacity (LCR and HCR, respectively) to evaluate the effects of exercise training on apoptosis and spermatogenesis in testis. Twenty-four 13-month-old male rats were assigned to four groups: control LCR (LCR-C), trained LCR (LCR-T), control HCR (HCR-C), and trained HCR (HCR-T). Ten key proteins connecting aerobic exercise capacity and general testes function were assessed, including those that are vital for mitochondrial biogenesis. The VO2 max of LCR-C group was about 30% lower than that of HCR-C rats, and the SIRT1 levels were also significantly lower than HCR-C. Twelve weeks of training significantly increased maximal oxygen consumption in LCR by nearly 40% whereas HCR remained unchanged. LCR-T had significantly higher levels of peroxisome proliferator-activated receptor-gamma coactivator-1 (PGC-1alpha), decreased levels of reactive oxygen species and increased acetylated p53 compared to LCR-C, while training produced no significant changes for these measures in HCR rats. BAX and Blc-2 were not different among all four groups. The levels of outer dense fibers -1 (Odf-1), a marker of spermatogenesis, increased in LCR-T rats, but decreased in HCR-TR rats. Moreover, exercise training increased the levels of lactate dehydrogenase C (LDHC) only in LCR rats. These data suggest that rats with low inborn exercise capacity can increase whole body oxygen consumption and running exercise capacity with endurance training and, in turn, increase spermatogenesis function via reduction in ROS and heightened activity of p53 in testes.},
	year = {2014},
	eissn = {1932-6203},
	orcid-numbers = {Koltai, Erika/0000-0002-1370-2955; Pósa, Anikó/0000-0003-2167-2888; Radák, Zsolt/0000-0003-1297-6804}
}