@article{MTMT:34744209, title = {Energy-Efficient Synthesis of Haloquinazolines and Their Suzuki Cross-Coupling Reactions in Propylene Carbonate}, url = {https://m2.mtmt.hu/api/publication/34744209}, author = {Piros, László and Krajsovszky, Gábor and Bogdán, Dóra and Gáti, T. and Szabó, P. and Horváth, Péter and Mándity, István}, doi = {10.1002/slct.202304969}, journal-iso = {CHEMISTRYSELECT}, journal = {CHEMISTRYSELECT}, volume = {9}, unique-id = {34744209}, issn = {2365-6549}, abstract = {Comparative synthesis of some new quinazoline derivatives via tetrakis(triphenylphosphine)palladium(0) catalysed Suzuki-Miyaura cross-coupling reaction in “green” propylene carbonate (PC) and dimethoxyethane. Three haloquinazolines were synthesised for Suzuki-cross-coupling from 5-bromoanthranilic acid. Sufficient and easy method for the elimination of PC is developed, thus the optimization of the synthesis of some quinazoline derivatives was carried out. Reactions with 2-chloro-6-bromo-3-phenylquinazolin-4(3H)-one proceeded faster and with a higher yield in PC than in dimethoxyethane, thus for some reactants PC is a good choice for greener synthesis. Practical considerations for using PC include shorter reaction times, improved yields, and the elimination of unnecessary solvent distillation, leading to significant energy savings. This facilitates the execution of energy-efficient reactions in a notably environmentally friendly solvent. In contrast to DME, the use of PC does not necessitate special pre-treatments. Moreover, less PC is required due to its high boiling point and low volatility. Considering these properties, coupled with the consistent need for chromatographic purification, the use of PC in the Suzuki-Miyaura cross-coupling reaction emerges as a superior and greener alternative compared to DME. © 2024 The Authors. ChemistrySelect published by Wiley-VCH GmbH.}, keywords = {PALLADIUM; cross-coupling; QUINAZOLINE; Green chemistry, Propylene carbonate}, year = {2024}, eissn = {2365-6549}, orcid-numbers = {Krajsovszky, Gábor/0000-0002-3224-4566; Bogdán, Dóra/0000-0003-4455-8914; Horváth, Péter/0000-0001-7149-4173; Mándity, István/0000-0003-2865-6143} } @book{MTMT:34433118, title = {Szerves kémia szemináriumok I.}, url = {https://m2.mtmt.hu/api/publication/34433118}, isbn = {9786155722301}, author = {Balogh, Balázs and Bogdán, Dóra and Czompa, Andrea and Deme, Ruth and Dunkel, Petra and Kaleta, Zoltán and Varró, Nikolett and Krajsovszky, Gábor and Mándity, István and Pollák, Patrik}, publisher = {Semmelweis Egyetem}, unique-id = {34433118}, year = {2023}, orcid-numbers = {Balogh, Balázs/0000-0001-7282-7283; Bogdán, Dóra/0000-0003-4455-8914; Czompa, Andrea/0000-0001-8442-8554; Deme, Ruth/0000-0002-0798-6912; Dunkel, Petra/0000-0001-5445-8357; Kaleta, Zoltán/0000-0003-2350-5100; Varró, Nikolett/0000-0003-4161-9021; Krajsovszky, Gábor/0000-0002-3224-4566; Mándity, István/0000-0003-2865-6143} } @book{MTMT:34315226, title = {Organic chemistry test questions. Semmelweis University, Faculty of Pharmaceutical Sciences, Department of Organic Chemistry}, url = {https://m2.mtmt.hu/api/publication/34315226}, isbn = {9786155722295}, author = {Balogh, Balázs and Bogdán, Dóra and Czompa, Andrea and Deme, Ruth and Dunkel, Petra and Ivánczi, Márton and Kárpáti, Levente and Krajsovszky, Gábor and Mándity, István and Tétényi, Péter}, publisher = {Semmelweis Kiadó és Multimédia Stúdió}, unique-id = {34315226}, year = {2023}, orcid-numbers = {Balogh, Balázs/0000-0001-7282-7283; Bogdán, Dóra/0000-0003-4455-8914; Czompa, Andrea/0000-0001-8442-8554; Deme, Ruth/0000-0002-0798-6912; Dunkel, Petra/0000-0001-5445-8357; Kárpáti, Levente/0000-0002-9091-3027; Krajsovszky, Gábor/0000-0002-3224-4566; Mándity, István/0000-0003-2865-6143} } @book{MTMT:34186753, title = {Szerves kémia tesztfeladatok}, url = {https://m2.mtmt.hu/api/publication/34186753}, isbn = {9786155722288}, author = {Balogh, Balázs and Bogdán, Dóra and Czompa, Andrea and Deme, Ruth and Dunkel, Petra and Ivánczi, Márton and Kárpáti, Levente and Krajsovszky, Gábor and Mándity, István and Tétényi, Péter}, publisher = {Semmelweis Egyetem}, unique-id = {34186753}, year = {2023}, orcid-numbers = {Balogh, Balázs/0000-0001-7282-7283; Bogdán, Dóra/0000-0003-4455-8914; Czompa, Andrea/0000-0001-8442-8554; Deme, Ruth/0000-0002-0798-6912; Dunkel, Petra/0000-0001-5445-8357; Krajsovszky, Gábor/0000-0002-3224-4566; Mándity, István/0000-0003-2865-6143} } @article{MTMT:34060723, title = {Continuous-flow regioselective reductive alkylation of oxindole with alcohols and aldehydes in a fast and economical manner}, url = {https://m2.mtmt.hu/api/publication/34060723}, author = {Mándoki, András and Orsy, György and Pászti, Zoltán and Porcs-Makkay, Márta and Bogdán, Dóra and Simig, Gyula and Mándity, István and Volk, Balázs}, doi = {10.1055/a-2122-4080}, journal-iso = {SYNTHESIS-STUTTGART}, journal = {SYNTHESIS-STUTTGART}, volume = {55}, unique-id = {34060723}, issn = {0039-7881}, abstract = {Oxindole is a widely used scaffold in drug discovery, which can be found in several marketed drugs, among them the widely used sunitinib or ziprasidone. Thus, the derivatization of oxindole is of considerable current interest. The extreme reaction conditions (high temperature, high pressure), described in the literature for the batchwise regioselective multistep 3-alkylation of oxindole with alcohols in the presence of Raney nickel, motivated us to develop a robust, time- and cost-efficient continuous-flow variant for this reaction. In addition, the continuous-flow technology was also extended to the reductive 3-alkylation of oxindole with aldehydes. The elaborated methodology allows the safe use of Raney nickel, this cheap and widely applied, albeit pyrophoric catalyst. Under the optimized reaction conditions, 10 oxindole derivatives were synthesized ranging from simple 3-alkyl to 3-aralkyl derivatives including two (trifluoromethyl)benzyl congeners. The technology is considerably robust and the catalyst showed a long-term usability. The model reaction between oxindole and acetaldehyde could be run for 19 h uninterruptedly, rendering possible the efficient ethylation of about 20 g oxindole utilizing only approximately 800 mg of Raney nickel.}, year = {2023}, eissn = {1437-210X}, pages = {4025-4033}, orcid-numbers = {Bogdán, Dóra/0000-0003-4455-8914; Simig, Gyula/0000-0002-2569-6476; Mándity, István/0000-0003-2865-6143; Volk, Balázs/0000-0002-2019-1874} } @article{MTMT:33961930, title = {Synthesis and characterization of 8-aminoquinoline photocages for biological applications}, url = {https://m2.mtmt.hu/api/publication/33961930}, author = {Kontra, Bence and Bogdán, Dóra and Alaghehmand, Behta and Csomos, Attila and Dunkel, Petra}, doi = {10.1016/j.tetlet.2023.154587}, journal-iso = {TETRAHEDRON LETT}, journal = {TETRAHEDRON LETTERS}, volume = {124}, unique-id = {33961930}, issn = {0040-4039}, year = {2023}, eissn = {1873-3581}, orcid-numbers = {Kontra, Bence/0000-0001-8293-3637; Bogdán, Dóra/0000-0003-4455-8914; Dunkel, Petra/0000-0001-5445-8357} } @article{MTMT:33369174, title = {Stimuli-Responsive Membrane Anchor Peptide Nanofoils for Tunable Membrane Association and Lipid Bilayer Fusion}, url = {https://m2.mtmt.hu/api/publication/33369174}, author = {Udyavara Nagaraj, Vignesh and Juhász, Tünde and Quemé Peña, Mayra and Szigyártó, Imola Csilla and Bogdán, Dóra and Wacha, András Ferenc and Mihály, Judith and Románszki, Loránd and Varga, Zoltán and Andréasson, Joakim and Mándity, István and Beke-Somfai, Tamás}, doi = {10.1021/acsami.2c11946}, journal-iso = {ACS APPL MATER INTER}, journal = {ACS APPLIED MATERIALS & INTERFACES}, volume = {14}, unique-id = {33369174}, issn = {1944-8244}, year = {2022}, eissn = {1944-8252}, pages = {55320-55331}, orcid-numbers = {Bogdán, Dóra/0000-0003-4455-8914; Wacha, András Ferenc/0000-0002-9609-0893; Varga, Zoltán/0000-0002-5741-2669; Andréasson, Joakim/0000-0003-4695-7943; Mándity, István/0000-0003-2865-6143} } @article{MTMT:33289419, title = {3-Aminopropylazetidines: facile synthesis and application for medicinal chemical purposes}, url = {https://m2.mtmt.hu/api/publication/33289419}, author = {Bogdán, Dóra and Kontra, Bence and Csomos, Attila and Kovács, Ervin and Mucsi, Zoltán and Dunkel, Petra}, doi = {10.24820/ark.5550190.p011.900}, journal-iso = {ARKIVOC}, journal = {ARKIVOC}, volume = {2022}, unique-id = {33289419}, issn = {1551-7012}, year = {2022}, eissn = {1551-7004}, pages = {272-287}, orcid-numbers = {Bogdán, Dóra/0000-0003-4455-8914; Kontra, Bence/0000-0001-8293-3637; Kovács, Ervin/0000-0002-3939-6925; Mucsi, Zoltán/0000-0003-3224-8847; Dunkel, Petra/0000-0001-5445-8357} } @article{MTMT:33191148, title = {Sel-assembled Peptide Bilayer for Photo-reversible Association on Lipid Membranes}, url = {https://m2.mtmt.hu/api/publication/33191148}, author = {Udyavara Nagaraj, Vignesh and Juhász, Tünde and Quemé Peña, Mayra and Szigyártó, Imola Csilla and Bogdán, Dóra and Wacha, András Ferenc and Mihály, Judith and Románszki, Loránd and Varga, Zoltán and Mándity, István and Beke-Somfai, Tamás}, doi = {10.1002/psc.3445}, journal-iso = {J PEPT SCI}, journal = {JOURNAL OF PEPTIDE SCIENCE}, volume = {28}, unique-id = {33191148}, issn = {1075-2617}, year = {2022}, eissn = {1099-1387}, orcid-numbers = {Bogdán, Dóra/0000-0003-4455-8914; Wacha, András Ferenc/0000-0002-9609-0893; Varga, Zoltán/0000-0002-5741-2669; Mándity, István/0000-0003-2865-6143} } @{MTMT:33096693, title = {Toward the green synthesis of peptides and peptidic drugs}, url = {https://m2.mtmt.hu/api/publication/33096693}, isbn = {9780128222485}, author = {Bogdán, Dóra and Kárpáti, Levente and Mándity, István}, booktitle = {Contemporary Chemical Approaches for Green and Sustainable Drugs}, doi = {10.1016/B978-0-12-822248-5.00002-4}, unique-id = {33096693}, year = {2022}, pages = {421-456}, orcid-numbers = {Bogdán, Dóra/0000-0003-4455-8914; Mándity, István/0000-0003-2865-6143} }