@article{MTMT:32020395, title = {Microbiomes in supragingival biofilms and saliva of adolescents with gingivitis and gingival health}, url = {https://m2.mtmt.hu/api/publication/32020395}, author = {Wirth, Roland and Maróti, Gergely and Lipták, Lídia and Mester, Mónika Klára and Al Ayoubi, Alaa and Pap, Bernadett and Madléna, Melinda and Minárovits, János and Kovács, Kornél Lajos}, doi = {10.1111/odi.13883}, journal-iso = {ORAL DIS}, journal = {ORAL DISEASES}, volume = {28}, unique-id = {32020395}, issn = {1354-523X}, abstract = {Background Important alterations exist in the microbiomes of supragingival biofilm and saliva samples from adolescent patients developing induced or spontaneous gingivitis relative to healthy controls. These and the relationships to dental health are not fully understood yet. Subjects and Methods Supragingival biofilm samples (n = 36) were collected from the teeth of 9 adolescents with gingivitis induced by orthodontic appliances, as well as dental plaques (n = 40) from 10 adolescents with spontaneous gingivitis, in addition to similar samples (n = 36) from 9 healthy controls. The bacterial metagenomes were analyzed by 16S rRNA gene amplicon sequencing. Salivary microbiomes of the same persons were characterized by shotgun metagenome sequencing. The data sets were examined using advanced bioinformatics workflows and two reference databases. Results The composition and diversity of bacterial communities did not differ extensively among the three study groups. Nevertheless, the relative abundances of the genera Fusobacterium, Akkermansia, Treponema, and Campylobacter were prominently higher in gingivitis patients versus controls. In contrast, the genera Lautropia, Kingella, Neisseria, Actinomyces, and Rothia were significantly more abundant in controls than in either of the two gingivitis groups. Conclusions The abundance pattern of certain taxa rather than individual strains shows characteristic features of potential diagnostic value. Stringent bioinformatics treatment of the sequencing data is mandatory to avoid unintentional misinterpretations.}, year = {2022}, eissn = {1601-0825}, pages = {2000-2014}, orcid-numbers = {Wirth, Roland/0000-0002-2383-2323; Maróti, Gergely/0000-0002-3705-0461; Madléna, Melinda/0000-0002-2154-3069; Kovács, Kornél Lajos/0000-0002-3926-0497} } @{MTMT:30805913, title = {A fogak sérülései}, url = {https://m2.mtmt.hu/api/publication/30805913}, author = {Madléna, Melinda and Lipták, Lídia and Gyulai-Gaál, Szabolcs}, booktitle = {Fogászat}, unique-id = {30805913}, year = {2019}, pages = {49-54}, orcid-numbers = {Madléna, Melinda/0000-0002-2154-3069} } @mastersthesis{MTMT:30741236, title = {Fogászati lakkok orális egészségre gyakorolt hatásának vizsgálata}, url = {https://m2.mtmt.hu/api/publication/30741236}, author = {Lipták, Lídia}, doi = {10.14753/SE.2019.2249}, unique-id = {30741236}, year = {2019} } @misc{MTMT:30676459, title = {Fogászati lakkok orális egészségre gyakorolt hatásának vizsgálata}, url = {https://m2.mtmt.hu/api/publication/30676459}, author = {Lipták, Lídia}, unique-id = {30676459}, year = {2018} } @CONFERENCE{MTMT:30421489, title = {Fogászati lakkok orális egészségre gyakorolt hatásának vizsgálata}, url = {https://m2.mtmt.hu/api/publication/30421489}, author = {Lipták, Lídia and Twetman, S. and Márton, Sándor József and Bársony, Nóra and Madléna, Melinda}, booktitle = {Translational interactive hands-on training and conference on epithelial ion transport including two symposia: "Antibacterial and mucolytic therapy in cystic fibrosis" and "Research in oral cavity – from basic science to clinical use"}, unique-id = {30421489}, year = {2018}, pages = {73}, orcid-numbers = {Madléna, Melinda/0000-0002-2154-3069} } @{MTMT:3419126, title = {Fogászati lakkok orális egészségre gyakorolt hatásának vizsgálata}, url = {https://m2.mtmt.hu/api/publication/3419126}, author = {Lipták, Lídia and Twetman, Svante and Márton, Sándor József and Bársony, Nóra and Madléna, Melinda}, booktitle = {Magyar Arc-, Állcsont- és Szájsebészeti Társaság XXII. Kongresszusa és Szegedi Fogorvos Találkozó}, unique-id = {3419126}, year = {2018}, pages = {69-69}, orcid-numbers = {Madléna, Melinda/0000-0002-2154-3069} } @article{MTMT:3333996, title = {Microbiological Changes and Caries-Preventive Effect of an Innovative Varnish Containing Chlorhexidine in Orthodontic Patients}, url = {https://m2.mtmt.hu/api/publication/3333996}, author = {Lipták, Lídia and Szabó, Krisztina and Nagy, Gábor and Márton, Sándor József and Madléna, Melinda}, doi = {10.1159/000486140}, journal-iso = {CARIES RES}, journal = {CARIES RESEARCH}, volume = {52}, unique-id = {3333996}, issn = {0008-6568}, abstract = {The aim of this study was to investigate the effects of Cervitec Plus(R) on the level of mutans streptococcus (SM) and lactobacillus (LB) colonies and the development of white spot lesions (WSLs) in patients with fixed orthodontic appliances. Informed consent was obtained from 32 volunteers (age 16.5 +/- 2.75 years). At baseline, levels of the bacterial colonies were determined in saliva and plaque using a chairside test (CRT Bacteria, Ivoclar-Vivadent, Schaan, Liechtenstein), and the number of WSLs was registered. After placing the fixed appliance, Cervitec Plus(R) or placebo varnishes (Ivoclar-Vivadent, Schaan, Liechtenstein) were applied monthly around the brackets and tubes, randomly in the right or left (test and placebo) quadrants of the same dental arch. SM and LB colonies in saliva and the SM colonies in plaque were determined on 11-21, 13-23, 15-25, and 16-26 teeth monthly over a 6-month period. At the sixth month, the number of new WSLs was determined. By the end of the study, compared with baseline, the ratio of saliva samples belonging to the low-risk category was significantly higher (p