@mastersthesis{MTMT:32477567,
	title = {2H-Azirinek új típusú reakciói [New reactions of 2H-azirines]},
	url = {https://m2.mtmt.hu/api/publication/32477567},
	author = {Angyal, Anikó},
	doi = {10.14232/phd.10754},
	publisher = {SZTE},
	unique-id = {32477567},
	year = {2021}
}

@article{MTMT:31499509,
	title = {Acid-Catalyzed 1,3-Dipolar Cycloaddition of 2H-Azirines with Nitrones: An Unexpected Access to 1,2,4,5-Tetrasubstituted Imidazoles},
	url = {https://m2.mtmt.hu/api/publication/31499509},
	author = {Angyal, Anikó and Demjen, Andras and Wölfling, János and Puskas, Laszlo G. and Kanizsai, Iván},
	doi = {10.1021/acs.joc.9b03288},
	journal-iso = {J ORG CHEM},
	journal = {JOURNAL OF ORGANIC CHEMISTRY},
	volume = {85},
	unique-id = {31499509},
	issn = {0022-3263},
	abstract = {The first 1,3-dipolar cycloaddition of 2H-azirines with nitrones, a straightforward approach toward the regioselective synthesis of 1,2,4,5-tetrasubstituted imidazoles, is reported. This trifluoroacetic acid-catalyzed protocol tolerates a broad range of aliphatic and aromatic substrates, offering an efficient access to highly diverse, multisubstituted imidazoles in isolated yields up to 83% under mild conditions.},
	year = {2020},
	eissn = {1520-6904},
	pages = {3587-3595},
	orcid-numbers = {Wölfling, János/0000-0002-3037-309X}
}

@article{MTMT:30641393,
	title = {1,3-Dipolar Cycloaddition of Isatin-Derived Azomethine Ylides with 2H-Azirines: Stereoselective Synthesis of 1,3-Diazaspiro[bicyclo[3.1.0]hexane]oxindoles},
	url = {https://m2.mtmt.hu/api/publication/30641393},
	author = {Angyal, Anikó and András, Demjén and Harmat, Veronika and Wölfling, János and László, G. Puskás and Kanizsai, Iván},
	doi = {10.1021/acs.joc.9b00242},
	journal-iso = {J ORG CHEM},
	journal = {JOURNAL OF ORGANIC CHEMISTRY},
	volume = {84},
	unique-id = {30641393},
	issn = {0022-3263},
	year = {2019},
	eissn = {1520-6904},
	pages = {4273-4281},
	orcid-numbers = {Harmat, Veronika/0000-0002-1866-9904; Wölfling, János/0000-0002-3037-309X}
}

@article{MTMT:3339611,
	title = {A green, isocyanide-based three-component reaction approach for the synthesis of multisubstituted ureas and thioureas},
	url = {https://m2.mtmt.hu/api/publication/3339611},
	author = {Angyal, Anikó and Demjén, András and Wölfling, János and Puskás, László and Kanizsai, Iván},
	doi = {10.1016/j.tetlet.2017.11.053},
	journal-iso = {TETRAHEDRON LETT},
	journal = {TETRAHEDRON LETTERS},
	volume = {59},
	unique-id = {3339611},
	issn = {0040-4039},
	abstract = {A one-pot, isocyanide based multicomponent protocol was presented starting from secondary amines towards (thio)urea derivatives and utilized for the construction of a diverse 27-membered chemical library. Following a green compatible microwave assisted condition, the formed N,N′-multisubstituted (thio)ureas were obtained in up to 85% yield. © 2017 Elsevier Ltd},
	keywords = {ARTICLE; WATER; chemical structure; multicomponent reaction; green chemistry; AMINE; substitution reaction; chlorine; microwave radiation; chemical reaction; urea; one pot synthesis; THIOUREA; sodium sulfide; thiourea derivative; CHLORINATION; urea derivative; isocyanide; N-chloro amine},
	year = {2018},
	eissn = {1873-3581},
	pages = {54-57},
	orcid-numbers = {Wölfling, János/0000-0002-3037-309X}
}

@article{MTMT:3389411,
	title = {Lewis Acid-Catalyzed Diastereoselective Synthesis of Multisubstituted N-Acylaziridine-2-carboxamides from 2H-Azirines via Joullie-Ugi Three-Component Reaction},
	url = {https://m2.mtmt.hu/api/publication/3389411},
	author = {Angyal, Anikó and Demjén, András and Wéber, Edit and Kovács, Anita Kármen and Wölfling, János and Puskás, László and Kanizsai, Iván},
	doi = {10.1021/acs.joc.7b03189},
	journal-iso = {J ORG CHEM},
	journal = {JOURNAL OF ORGANIC CHEMISTRY},
	volume = {83},
	unique-id = {3389411},
	issn = {0022-3263},
	abstract = {A ZnCl2-catalyzed diastereoselective Joullie Ugi three-component reaction from 2H-azirines, isocyanides, and carboxylic acids was established. The protocol allows the preparation of highly and diversely functionalized N-acylaziridine-2-carboxamide derivatives in up to 82% isolated yields. Moreover, the applicability of N-acylaziridines is demonstrated through a variety of transformations.},
	keywords = {ASYMMETRIC-SYNTHESIS; CYSTEINE PROTEASES; enantioselective synthesis; MULTICOMPONENT REACTIONS; N-ACYLAZIRIDINES; 3+2 CYCLOADDITION; CARBOXYLIC ESTERS; AZIRIDINYL PEPTIDES; 2,4-DISUBSTITUTED OXAZOLES; SUBSTITUTED PROLYL PEPTIDES},
	year = {2018},
	eissn = {1520-6904},
	pages = {3570-3581},
	orcid-numbers = {Wéber, Edit/0000-0002-5904-0619; Kovács, Anita Kármen/0000-0001-9805-1647; Wölfling, János/0000-0002-3037-309X}
}

@article{MTMT:3389413,
	title = {One-pot synthesis of diverse N,N '-disubstituted guanidines from N-chlorophthalimide, isocyanides and amines via N-phthaloyl-guanidines},
	url = {https://m2.mtmt.hu/api/publication/3389413},
	author = {Demjén, András and Angyal, Anikó and Wölfling, János and Puskás, László and Kanizsai, Iván},
	doi = {10.1039/c7ob03109b},
	journal-iso = {ORG BIOMOL CHEM},
	journal = {ORGANIC & BIOMOLECULAR CHEMISTRY},
	volume = {16},
	unique-id = {3389413},
	issn = {1477-0520},
	abstract = {A sequential one-pot approach towards N,N-disubstituted guanidines from N-chlorophthalimide, isocyanides and amines is reported. This strategy provides straightforward and efficient access to diverse guanidines in yields up to 81% through previously unprecedented N-phthaloylguanidines. This protocol also features wide substrate scope and mild conditions.},
	keywords = {AGENTS; AMIDINES; CONVENIENT SYNTHESIS; BIOLOGICAL-ACTIVITIES; SECONDARY-AMINES; CONCISE SYNTHESIS; CATALYTIC ADDITION; EFFICIENT GUANYLATION; DISUBSTITUTED GUANIDINES; SUBSTITUTED GUANIDINES},
	year = {2018},
	eissn = {1477-0539},
	pages = {2143-2149},
	orcid-numbers = {Wölfling, János/0000-0002-3037-309X}
}

@article{MTMT:3399467,
	title = {Synthesis, cytotoxic characterization, and SAR study of imidazo[1,2-b]pyrazole-7-carboxamides},
	url = {https://m2.mtmt.hu/api/publication/3399467},
	author = {Demjen, A and Alföldi, Róbert and Angyal, Anikó and Gyuris, M and Hackler, L and Szebeni, Gábor and Wölfling, János and Puskás, László and Kanizsai, Iván},
	doi = {10.1002/ardp.201800062},
	journal-iso = {ARCH PHARM},
	journal = {ARCHIV DER PHARMAZIE},
	volume = {351},
	unique-id = {3399467},
	issn = {0365-6233},
	abstract = {The synthesis and in vitro cytotoxic characteristics of new imidazo[1,2-b]pyrazole-7-carboxamides were investigated. Following a hit-to-lead optimization exploiting 2D and 3D cultures of MCF-7 human breast, 4T1 mammary gland, and HL-60 human promyelocytic leukemia cancer cell lines, a 67-membered library was constructed and the structure-activity relationship (SAR) was determined. Seven synthesized analogues exhibited sub-micromolar activities, from which compound 63 exerted the most significant potency with a remarkable HL-60 sensitivity (IC50=0.183M).},
	keywords = {IN-VIVO; MULTICOMPONENT REACTIONS; BIOLOGICAL EVALUATION; multicomponent reaction; Anticancer agents; kinase inhibitors; Cytotoxic; Aurora Kinases; Groebke-Blackburn-Bienayme reaction; LEAD OPTIMIZATION; ANTITUMOR EVALUATION; ANTIMICROBIAL EVALUATION; PYRAZOLE DERIVATIVES; 2-b]pyrazole; imidazo[1},
	year = {2018},
	eissn = {1521-4184},
	orcid-numbers = {Szebeni, Gábor/0000-0002-6998-5632; Wölfling, János/0000-0002-3037-309X}
}