@article{MTMT:33230159,
	title = {Vitamin B12 (Cobalamin): Its Fate from Ingestion to Metabolism with Particular Emphasis on Diagnostic Approaches of Acquired Neonatal/Infantile Deficiency Detected by Newborn Screening},
	url = {https://m2.mtmt.hu/api/publication/33230159},
	author = {Kósa, Magdolna and Galla, Zsolt and Lénárt, István and Baráth, Ákos and Grecsó, Nóra and Rácz, Gábor Zoltán and Bereczki, Csaba and Monostori, Péter},
	doi = {10.3390/metabo12111104},
	journal-iso = {METABOLITES},
	journal = {METABOLITES},
	volume = {12},
	unique-id = {33230159},
	issn = {2218-1989},
	abstract = {Acquired vitamin B12 (vB12) deficiency (vB12D) of newborns is relatively frequent as compared with the incidence of inherited diseases included in newborn screening (NBS) of different countries across the globe. Infants may present signs of vB12D before 6 months of age with anemia and/or neurologic symptoms when not diagnosed in asymptomatic state. The possibility of identifying vitamin deficient mothers after their pregnancy during the breastfeeding period could be an additional benefit of the newborn screening. Vitamin supplementation is widely available and easy to administer. However, in many laboratories, vB12D is not included in the national screening program. Optimized screening requires either second-tier testing or analysis of new urine and blood samples combined with multiple clinical and laboratory follow ups. Our scope was to review the physiologic fate of vB12 and the pathobiochemical consequences of vB12D in the human body. Particular emphasis was put on the latest approaches for diagnosis and treatment of vB12D in NBS.},
	year = {2022},
	eissn = {2218-1989},
	orcid-numbers = {Kósa, Magdolna/0000-0002-0642-9882; Galla, Zsolt/0000-0002-9166-1212; Grecsó, Nóra/0000-0003-4323-1872; Rácz, Gábor Zoltán/0000-0002-3571-4463; Bereczki, Csaba/0000-0003-0091-3558; Monostori, Péter/0000-0003-3591-6054}
}

@{MTMT:32923831,
	title = {Elválasztástechnika és kapcsolt módszerek a klinikai diagnosztikában},
	url = {https://m2.mtmt.hu/api/publication/32923831},
	author = {Monostori, Péter and Baráth, Ákos and Galla, Zsolt and Grecsó, Nóra and Bereczki, Csaba},
	booktitle = {METT25 a Magyar Elválasztástudományi Társaság jubileumi konferenciája},
	unique-id = {32923831},
	year = {2021},
	pages = {36},
	orcid-numbers = {Monostori, Péter/0000-0003-3591-6054; Galla, Zsolt/0000-0002-9166-1212; Grecsó, Nóra/0000-0003-4323-1872; Bereczki, Csaba/0000-0003-0091-3558}
}

@article{MTMT:32289305,
	title = {Comparison of different preparation techniques of dried blood spot quality controls in newborn screening for congenital adrenal hyperplasia},
	url = {https://m2.mtmt.hu/api/publication/32289305},
	author = {Grecsó, Nóra and Zadori, Anita and Baráth, Ákos and Galla, Zsolt and Rácz, Gábor Zoltán and Bereczki, Csaba and Monostori, Péter},
	doi = {10.1371/journal.pone.0252091},
	journal-iso = {PLOS ONE},
	journal = {PLOS ONE},
	volume = {16},
	unique-id = {32289305},
	issn = {1932-6203},
	abstract = {In newborn screening, samples suspected for congenital adrenal hyperplasia (CAH), a potentially lethal inborn error of steroid biosynthesis, need to be confirmed using liquid chromatography-tandem mass spectrometry. Daily quality controls (QCs) for the 2(nd)-tier CAH assay are not commercially available and are therefore generally prepared within the laboratory. For the first time, we aimed to compare five different QC preparation approaches used in routine diagnostics for CAH on the concentrations of cortisol, 21-deoxycortisol, 11-deoxycortisol, 4-androstenedione and 17-hydroxyprogesterone in dried blood spots. The techniques from Prep1 to Prep5 were tested at two analyte concentrations by spiking aliquots of a steroid-depleted blood, derived from washed erythrocyte suspension and steroid-depleted serum. The preparation processes differed in the sequence of the preparation steps and whether freeze-thaw cycles were used to facilitate blood homogeneity. The five types of dried blood spot QCs were assayed and quantitated in duplicate on five different days using a single calibration row per day. Inter-assay variations less than 15% and concentrations within +/- 15% of the nominal values were considered acceptable. Results obtained by means of the four dried blood spot QC preparation techniques (Prep1, Prep2, Prep4 and Prep5) were statistically similar and remained within the +/- 15% ranges in terms of both reproducibility and nominal values. However, concentration results for Prep3 (spiking prior to three freeze-thaw cycles) were significantly lower than the nominal values in this setting, with differences exceeding the +/- 15% range in many cases despite acceptable inter-assay variations. These findings have implications for the in-house preparation of QC samples in laboratory developed tests for CAH, including 2(nd)-tier assays in newborn screening.},
	year = {2021},
	eissn = {1932-6203},
	orcid-numbers = {Grecsó, Nóra/0000-0003-4323-1872; Galla, Zsolt/0000-0002-9166-1212; Rácz, Gábor Zoltán/0000-0002-3571-4463; Bereczki, Csaba/0000-0003-0091-3558; Monostori, Péter/0000-0003-3591-6054}
}

@article{MTMT:32092570,
	title = {Improved LC-MS/MS method for the determination of 42 neurologically and metabolically important molecules in urine},
	url = {https://m2.mtmt.hu/api/publication/32092570},
	author = {Galla, Zsolt and Rácz, Gábor Zoltán and Grecsó, Nóra and Baráth, Ákos and Kósa, Magdolna and Bereczki, Csaba and Monostori, Péter},
	doi = {10.1016/j.jchromb.2021.122846},
	journal-iso = {J CHROMATOGR B},
	journal = {JOURNAL OF CHROMATOGRAPHY B},
	volume = {1179},
	unique-id = {32092570},
	issn = {1570-0232},
	year = {2021},
	eissn = {1873-376X},
	orcid-numbers = {Galla, Zsolt/0000-0002-9166-1212; Rácz, Gábor Zoltán/0000-0002-3571-4463; Grecsó, Nóra/0000-0003-4323-1872; Kósa, Magdolna/0000-0002-0642-9882; Bereczki, Csaba/0000-0003-0091-3558; Monostori, Péter/0000-0003-3591-6054}
}

@article{MTMT:31749099,
	title = {Simultaneous determination of 30 neurologically and metabolically important molecules: A sensitive and selective way to measure tyrosine and tryptophan pathway metabolites and other biomarkers in human serum and cerebrospinal fluid},
	url = {https://m2.mtmt.hu/api/publication/31749099},
	author = {Galla, Zsolt and Rajda, Cecília and Rácz, Gábor Zoltán and Grecsó, Nóra and Baráth, Ákos and Vécsei, László and Bereczki, Csaba and Monostori, Péter},
	doi = {10.1016/j.chroma.2020.461775},
	journal-iso = {J CHROMATOGR A},
	journal = {JOURNAL OF CHROMATOGRAPHY A},
	volume = {1635},
	unique-id = {31749099},
	issn = {0021-9673},
	year = {2021},
	eissn = {1873-3778},
	orcid-numbers = {Galla, Zsolt/0000-0002-9166-1212; Rajda, Cecília/0000-0002-0252-4778; Rácz, Gábor Zoltán/0000-0002-3571-4463; Grecsó, Nóra/0000-0003-4323-1872; Vécsei, László/0000-0001-8037-3672; Bereczki, Csaba/0000-0003-0091-3558; Monostori, Péter/0000-0003-3591-6054}
}

@article{MTMT:31332527,
	title = {Storage stability of five steroids and in dried blood spots for newborn screening and retrospective diagnosis of congenital adrenal hyperplasia},
	url = {https://m2.mtmt.hu/api/publication/31332527},
	author = {Grecsó, Nóra and Zádori, Anita and Szécsi, Ilona and Baráth, Ákos and Galla, Zsolt and Bereczki, Csaba and Monostori, Péter},
	doi = {10.1371/journal.pone.0233724},
	journal-iso = {PLOS ONE},
	journal = {PLOS ONE},
	volume = {15},
	unique-id = {31332527},
	issn = {1932-6203},
	year = {2020},
	eissn = {1932-6203},
	orcid-numbers = {Grecsó, Nóra/0000-0003-4323-1872; Galla, Zsolt/0000-0002-9166-1212; Bereczki, Csaba/0000-0003-0091-3558; Monostori, Péter/0000-0003-3591-6054}
}

@mastersthesis{MTMT:3266894,
	title = {Investigation of Novel Cinchona Alkaloid-based Zwitterionic Chiral Stationary Phases in Cation- and Zwitterion-Exchange Modes},
	url = {https://m2.mtmt.hu/api/publication/3266894},
	author = {Grecsó, Nóra},
	doi = {10.14232/phd.3973},
	publisher = {SZTE},
	unique-id = {3266894},
	year = {2017},
	orcid-numbers = {Grecsó, Nóra/0000-0003-4323-1872}
}

@article{MTMT:3256483,
	title = {Liquid chromatographic enantioseparation of carbocyclic β-amino acids possessing limonene skeleton on macrocyclic glycopeptide-based chiral stationary phases},
	url = {https://m2.mtmt.hu/api/publication/3256483},
	author = {Orosz, Tímea and Grecsó, Nóra and Lajkó, Gyula and Szakonyi, Zsolt and Fülöp, Ferenc and Armstrong, DW and Ilisz, István and Péter, Antal},
	doi = {10.1016/j.jpba.2017.06.010},
	journal-iso = {J PHARMACEUT BIOMED ANAL},
	journal = {JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS},
	volume = {145},
	unique-id = {3256483},
	issn = {0731-7085},
	abstract = {Polar-ionic and reversed-phase high-performance liquid chromatographic separations of limonene-based cyclic β-amino acid enantiomers were carried out by using macrocyclic glycopeptide-based chiral selectors applying Chirobiotic T, TAG and R columns. The effects of additives, concentration of the co- and counter-ions and the temperature in polar-ionic mobile phase systems were studied. The influence of pH, MeOH content and alcohol additives were investigated in the reversed-phase mode. The difference in the change in standard enthalpy Δ(ΔH°), entropy Δ(ΔS°), and free energy Δ(ΔG°) was calculated from the linear van't Hoff plots derived from the ln α vs 1/T curves in the temperature range 5–40 °C. Unusual temperature behavior was observed on Chirobiotic TAG for most of the analytes: decreased retention times were accompanied with increased separation factors with increasing temperature, and separation was entropically-driven. For two of the studied analytes enthalpically-driven enantioseparations were observed. The elution sequence was determined in all cases, but no general rule could be established. © 2017 Elsevier B.V.},
	keywords = {enantiomer separation; high-performance liquid chromatography (HPLC); Macrocyclic glycopeptide-based chiral stationary phases; Carbocyclic β-amino acids},
	year = {2017},
	eissn = {1873-264X},
	pages = {119-126},
	orcid-numbers = {Grecsó, Nóra/0000-0003-4323-1872; Szakonyi, Zsolt/0000-0003-2432-8409; Fülöp, Ferenc/0000-0003-1066-5287; Ilisz, István/0000-0001-8282-457X}
}

@article{MTMT:3244835,
	title = {Liquid and subcritical fluid chromatographic enantioseparation of Nα-Fmoc proteinogenic amino acids on Quinidine-based zwitterionic and anion-exchanger type chiral stationary phases. A comparative study.},
	url = {https://m2.mtmt.hu/api/publication/3244835},
	author = {Lajkó, Gyula and Grecsó, Nóra and Tóth, Gábor and Fülöp, Ferenc and Lindner, Wolfgang and Ilisz, István and Péter, Antal},
	doi = {10.1002/chir.22700},
	journal-iso = {CHIRALITY},
	journal = {CHIRALITY: THE PHARMACOLOGICAL BIOLOGICAL AND CHEMICAL CONSEQUENCES OF MOLECULAR ASYMMETRY},
	volume = {29},
	unique-id = {3244835},
	issn = {0899-0042},
	abstract = {Stereoselective high-performance liq. chromatog. and subcrit. fluid chromatog. sepns. of 19 Nα-Fmoc proteinogenic amino acid enantiomers were carried out by using Quinidine-based zwitterionic and anion-exchanger-type chiral stationary phases Chiralpak ZWIX(-) and QD-AX. For optimization of retention and enantioselectivity, the ratio of bulk solvent components (MeOH/MeCN, H2O/MeOH, or CO2/MeOH) and the nature and concn. of the acid and base additives (counter- and co-ions) were systematically varied. The effect of column temp. on the enantiosepn. was investigated and thermodn. parameters were calcd. from the van't Hoff plots ln α vs. 1/T. The thermodn. parameters revealed that the enantiosepns. were enthalpy-driven. The elution sequence was detd. in all cases and with the exception of Fmoc-Cys(Trt)-OH, it was identical on both chiral stationary phases whereby the L-enantiomers eluted before the D-enantiomers. [on SciFinder(R)]},
	year = {2017},
	eissn = {1520-636X},
	pages = {225-238},
	orcid-numbers = {Grecsó, Nóra/0000-0003-4323-1872; Tóth, Gábor/0000-0002-3604-4385; Fülöp, Ferenc/0000-0003-1066-5287; Ilisz, István/0000-0001-8282-457X}
}

@article{MTMT:3154880,
	title = {A comparative study of enantioseparations of Nα-Fmoc proteinogenic amino acids on Quinine-based zwitterionic and anion exchanger-type chiral stationary phases under hydro-organic liquid and subcritical fluid chromatographic conditions},
	url = {https://m2.mtmt.hu/api/publication/3154880},
	author = {Lajkó, Gyula and Grecsó, Nóra and Tóth, Gábor and Fülöp, Ferenc and Lindner, W and Péter, Antal and Ilisz, István},
	doi = {10.3390/molecules21111579},
	journal-iso = {MOLECULES},
	journal = {MOLECULES},
	volume = {21},
	unique-id = {3154880},
	issn = {1420-3049},
	abstract = {The focus of this contribution is a comparative investigation of enantioseparations of 19 Nα-Fmoc proteinogenic amino acids on Quinine-based zwitterionic and anion-exchanger type chiral stationary phases employing hydro-organic and polar-ionic liquid and subcritical fluid chromatographic conditions. Effects of mobile phase composition (including additives, e.g., water, basis and acids) and nature of chiral selectors on the chromatographic performances were studied at different chromatographic modes. Thermodynamic parameters of the temperature dependent enantioseparation results were calculated in the temperature range 5-50°C applying plots of lnα versus 1/T. The differences in standard enthalpy and standard entropy for a given pair of enantiomers were calculated and served as a basis for comparisons. Elution sequence in all cases was determined, where a general rule could be observed, both in liquid and subcritical fluid chromatographic mode the D-enantiomers eluted before the L ones. In both modes, the principles of ion exchange chromatography apply. © 2016 by the authors; licensee MDPI.},
	keywords = {enantiomer separation; temperature effect; Zwitterionic chiral stationary phase; Weak anion-exchange chiral stationary phase; Subcritical fluid chromatography; Nα-Fmoc-protected proteinogenic amino acids; Hydro-organic liquid chromatography},
	year = {2016},
	eissn = {1420-3049},
	orcid-numbers = {Grecsó, Nóra/0000-0003-4323-1872; Fülöp, Ferenc/0000-0003-1066-5287; Ilisz, István/0000-0001-8282-457X}
}