@article{MTMT:34830192,
	title = {Immobilization of human tyrosine hydroxylase onto magnetic nanoparticles – A novel formulation of a therapeutic enzyme},
	url = {https://m2.mtmt.hu/api/publication/34830192},
	author = {Molnár, Zsófia Klára and Koplányi, Gábor and Farkas, Réka and Péli, Noémi and Kenéz, Balázs and Decsi, Balázs and Katona, Gábor and Balogh, György Tibor and Vértessy, Beáta (Grolmuszné) and Balogh Weiser, Diána},
	doi = {10.1016/j.ijbiomac.2024.131939},
	journal-iso = {INT J BIOL MACROMOL},
	journal = {INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES},
	volume = {268},
	unique-id = {34830192},
	issn = {0141-8130},
	abstract = {Human tyrosine hydroxylase (hTH) has key role in the production of catecholamine neurotransmitters. The structure, function and regulation of hTH has been extensively researched area and the possibility of enzyme replacement therapy (ERT) involving hTH through nanocarriers has been raised as well. However, our understanding on how hTH may interact with nanocarriers is still lacking. In this work, we attempted to investigate the immobilization of hTH on magnetic nanoparticles (MNPs) with various surface linkers in quantitative and mechanistic detail. Our results showed that the activity of hTH was retained after immobilization via secondary and covalent interactions as well. The colloidal stability of hTH could be also enhanced proved by Dynamic light scattering and Zeta potential analysis and a homogenous enzyme layer could be achieved, which was investigated by Raman mapping. The covalent attachment of hTH on MNPs via aldehyde or epoxy linkers provide irreversible immobilization and 38.1 % and 16.5 % recovery (ER). The hTH-MNPs catalyst had 25 % ER in average in simulated nasal electrolyte solution (SNES). This outcome highlights the relevance of immobilization applying MNPs as a potential formulation tool of sensitive therapeutic enzymes offering new opportunities for ERT related to neurodegenerative disorders. © 2024 The Author(s)},
	year = {2024},
	eissn = {1879-0003},
	orcid-numbers = {Koplányi, Gábor/0000-0002-3791-1057; Katona, Gábor/0000-0003-1564-4813; Balogh, György Tibor/0000-0003-3347-1880; Balogh Weiser, Diána/0000-0002-9957-1203}
}

@article{MTMT:34791444,
	title = {Essential considerations towards development of effective nasal antibiotic formulation: features, strategies, and future directions},
	url = {https://m2.mtmt.hu/api/publication/34791444},
	author = {Mardikasari, Sandra Aulia and Katona, Gábor and Sipos, Bence and Pannonhalminé Csóka, Ildikó},
	doi = {10.1080/17425247.2024.2341184},
	journal-iso = {EXPERT OPIN DRUG DELIV},
	journal = {EXPERT OPINION ON DRUG DELIVERY},
	unique-id = {34791444},
	issn = {1742-5247},
	year = {2024},
	eissn = {1744-7593},
	pages = {1-15},
	orcid-numbers = {Mardikasari, Sandra Aulia/0000-0001-6771-0208; Katona, Gábor/0000-0003-1564-4813; Sipos, Bence/0000-0002-0131-4728; Pannonhalminé Csóka, Ildikó/0000-0003-0807-2781}
}

@CONFERENCE{MTMT:34770849,
	title = {Development of functionalized protein-based nanoparticles for improved drug delivery of antineurodegenerative drugs},
	url = {https://m2.mtmt.hu/api/publication/34770849},
	author = {Mohammad, Hanan and Katona, Gábor and Pannonhalminé Csóka, Ildikó},
	booktitle = {VI. Symposium of Young Researchers on PharmaceuticalTechnology, Biotechnology and Regulatory Science},
	doi = {10.14232/syrptbrs.2024.61},
	unique-id = {34770849},
	year = {2024},
	pages = {61-61},
	orcid-numbers = {Katona, Gábor/0000-0003-1564-4813; Pannonhalminé Csóka, Ildikó/0000-0003-0807-2781}
}

@CONFERENCE{MTMT:34770843,
	title = {Formulation and optimization of rifampicin-loaded niosomes for ocular delivery system},
	url = {https://m2.mtmt.hu/api/publication/34770843},
	author = {Salamah, Maryana and Balogh, György Tibor and Katona, Gábor},
	booktitle = {VI. Symposium of Young Researchers on PharmaceuticalTechnology, Biotechnology and Regulatory Science},
	doi = {10.14232/syrptbrs.2024.48},
	unique-id = {34770843},
	year = {2024},
	pages = {48-48},
	orcid-numbers = {Balogh, György Tibor/0000-0001-8273-1760; Katona, Gábor/0000-0003-1564-4813}
}

@CONFERENCE{MTMT:34770823,
	title = {Design, development and investigation of dexamethasone sodium phosphate-containing dissolving microneedle arrays},
	url = {https://m2.mtmt.hu/api/publication/34770823},
	author = {Cseh, Martin and Katona, Gábor and Berkó, Szilvia and Pannonhalminé Csóka, Ildikó},
	booktitle = {VI. Symposium of Young Researchers on PharmaceuticalTechnology, Biotechnology and Regulatory Science},
	doi = {10.14232/syrptbrs.2024.24},
	unique-id = {34770823},
	year = {2024},
	pages = {24-24},
	orcid-numbers = {Katona, Gábor/0000-0003-1564-4813; Berkó, Szilvia/0000-0002-3842-8876; Pannonhalminé Csóka, Ildikó/0000-0003-0807-2781}
}

@CONFERENCE{MTMT:34770795,
	title = {Development of in situ ionic-sensitive nasal gels of amoxicillin-loaded albumin nanoparticle applying QbD-based optimization for improved local delivery},
	url = {https://m2.mtmt.hu/api/publication/34770795},
	author = {Mardikasari, Sandra Aulia and Katona, Gábor and Budai-Szűcs, Mária and Sipos, Bence and Orosz, László and Burián, Katalin and Rovó, László and Pannonhalminé Csóka, Ildikó},
	booktitle = {VI. Symposium of Young Researchers on PharmaceuticalTechnology, Biotechnology and Regulatory Science},
	doi = {10.14232/syrptbrs.2024.18},
	unique-id = {34770795},
	year = {2024},
	pages = {18-18},
	orcid-numbers = {Mardikasari, Sandra Aulia/0000-0001-6771-0208; Katona, Gábor/0000-0003-1564-4813; Budai-Szűcs, Mária/0000-0001-5187-5702; Sipos, Bence/0000-0002-0131-4728; Burián, Katalin/0000-0003-1300-2374; Rovó, László/0000-0003-1782-1756; Pannonhalminé Csóka, Ildikó/0000-0003-0807-2781}
}

@article{MTMT:34538437,
	title = {A Comparative Pharmacokinetic Study for Cysteamine-Containing Eye Drops as an Orphan Topical Therapy in Cystinosis},
	url = {https://m2.mtmt.hu/api/publication/34538437},
	author = {Csorba, Anita and Katona, Gábor and Budai-Szűcs, Mária and Balogh Weiser, Diána and Molnár, P. and Maka, Erika and Nochta-Kazsoki, Adrienn Katalin and Vajna, Márton Antal and Zelkó, Romána and Nagy, Zoltán Zsolt and Balogh, György Tibor},
	doi = {10.3390/ijms25031623},
	journal-iso = {INT J MOL SCI},
	journal = {INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES},
	volume = {25},
	unique-id = {34538437},
	issn = {1661-6596},
	year = {2024},
	eissn = {1422-0067},
	orcid-numbers = {Csorba, Anita/0000-0002-3256-9440; Katona, Gábor/0000-0003-1564-4813; Budai-Szűcs, Mária/0000-0001-5187-5702; Balogh Weiser, Diána/0000-0002-9957-1203; Maka, Erika/0000-0002-3631-3506; Nochta-Kazsoki, Adrienn Katalin/0000-0002-0611-3124; Vajna, Márton Antal/0000-0001-5280-7533; Zelkó, Romána/0000-0002-5419-9137; Nagy, Zoltán Zsolt/0000-0002-7330-0464; Balogh, György Tibor/0000-0003-3347-1880}
}

@{MTMT:34480647,
	title = {Challenges and Progress in Nose-to-Brain Drug Delivery},
	url = {https://m2.mtmt.hu/api/publication/34480647},
	author = {Himawan, Achmad and Mardikasari, Sandra Aulia and Katona, Gábor and Vora, Lalitkumar K. and Pandya, Anjali Kiran and Permana, Andi Dian and Abu Ershaid, Juhaina M. and Larrañeta, Eeneko and Patravale, Vandana},
	booktitle = {Nanoarchitectonics for Brain Drug Delivery},
	doi = {10.1201/9781032661964-4},
	unique-id = {34480647},
	year = {2024},
	pages = {71-105},
	orcid-numbers = {Mardikasari, Sandra Aulia/0000-0001-6771-0208; Katona, Gábor/0000-0003-1564-4813}
}

@article{MTMT:34318204,
	title = {Preparation and Optimization of Bovine Serum Albumin Nanoparticles as a Promising Gelling System for Enhanced Nasal Drug Administration},
	url = {https://m2.mtmt.hu/api/publication/34318204},
	author = {Mardikasari, Sandra Aulia and Katona, Gábor and Sipos, Bence and Ambrus, Rita and Pannonhalminé Csóka, Ildikó},
	doi = {10.3390/gels9110896},
	journal-iso = {GELS-BASEL},
	journal = {GELS (BASEL)},
	volume = {9},
	unique-id = {34318204},
	abstract = {Bovine serum albumin (BSA) has been used extensively as a suitable carrier system for alternative drug delivery routes, such as nasal administration. However, the optimization of BSA nanoparticles with respect to their nasal applicability has not been widely studied. The present study focuses on the characterization of BSA nanoparticles prepared using the desolvation method, followed by a gelation process to facilitate intranasal drug delivery. The results demonstrated that the ratio of BSA and the desolvating agent, ethanol, played a critical role in the nanoparticle characteristics of the BSA nanogel matrices (BSA-NGs). Based on the gelling properties, the formulations of BSA-NG 2, BSA-NG 4, and BSA-NG 6 were selected for further investigation. The Raman spectra confirmed that there were no specific changes to the secondary structures of the BSA. The mucoadhesion studies revealed moderately high mucoadhesive properties, with a mucin binding efficiency (MBE) value of around 67%, allowing the dose to avoid elimination due to rapid mucociliary clearance of the nasal passage. Via studying the nexus of the carrier system, BSA-NGs loaded with dexamethasone as a model drug were prepared and evaluated by differential scanning calorimetry (DSC) and thermal gravimetry (TG), ascertaining that no ethanol remained in the samples after the freeze-drying process. Furthermore, the viscosity measurements exhibited moderate viscosity, which is suitable for nasal liquid preparations. The in vitro release studies performed with a simulated nasal electrolyte solution (SNES) medium showed 88.15–95.47% drug release within 4 h. In conclusion, BSA nanoparticle gelling matrices can offer potential, value-added drug delivery carriers for improved nasal drug administration.},
	year = {2023},
	eissn = {2310-2861},
	orcid-numbers = {Mardikasari, Sandra Aulia/0000-0001-6771-0208; Katona, Gábor/0000-0003-1564-4813; Sipos, Bence/0000-0002-0131-4728; Pannonhalminé Csóka, Ildikó/0000-0003-0807-2781}
}

@article{MTMT:34225112,
	title = {Development of innovative electrospun nepafenac-loaded nanofibers-based ophthalmic inserts},
	url = {https://m2.mtmt.hu/api/publication/34225112},
	author = {Safaa, Mohammed Omer and Nagy, Nándor and Szőcs, Emőke and Kádár, Szabina and Völgyi, Gergely and Pinke, Balázs and Mészáros, László and Katona, Gábor and Vincze, Anna and Dormán, Péter and Nagy, Zoltán Zsolt and Balogh, György Tibor and Nochta-Kazsoki, Adrienn Katalin and Zelkó, Romána},
	doi = {10.1016/j.ijpharm.2023.123554},
	journal-iso = {INT J PHARM},
	journal = {INTERNATIONAL JOURNAL OF PHARMACEUTICS},
	volume = {647},
	unique-id = {34225112},
	issn = {0378-5173},
	year = {2023},
	eissn = {1873-3476},
	orcid-numbers = {Safaa, Mohammed Omer/0000-0003-4212-9147; Nagy, Nándor/0000-0002-6223-5214; Völgyi, Gergely/0000-0001-8990-3916; Pinke, Balázs/0000-0002-6683-6199; Mészáros, László/0000-0001-5979-7403; Katona, Gábor/0000-0003-1564-4813; Nagy, Zoltán Zsolt/0000-0002-7330-0464; Balogh, György Tibor/0000-0003-3347-1880; Nochta-Kazsoki, Adrienn Katalin/0000-0002-0611-3124; Zelkó, Romána/0000-0002-5419-9137}
}