@article{MTMT:34780181,
	title = {Ion-Specific Effects on the Structure, Size, and Charge of Polymers Applied in Enhanced Oil Recovery},
	url = {https://m2.mtmt.hu/api/publication/34780181},
	author = {Árok, Zsófia and Sáringer, Szilárd and Papp, Gréta and Juhász, Ádám and Puskás, Sándor and Szilágyi, István},
	doi = {10.1021/acs.energyfuels.4c00423},
	journal-iso = {ENERG FUEL},
	journal = {ENERGY AND FUELS},
	unique-id = {34780181},
	issn = {0887-0624},
	year = {2024},
	eissn = {1520-5029},
	orcid-numbers = {Sáringer, Szilárd/0000-0002-1906-8094; Juhász, Ádám/0000-0003-0033-7968; Szilágyi, István/0000-0001-7289-0979}
}

@article{MTMT:34689790,
	title = {Tryptophanhydroxamic Acid-Stabilized Ultrasmall Gold Nanoclusters: Tuning the Selectivity for Metal Ion Sensing},
	url = {https://m2.mtmt.hu/api/publication/34689790},
	author = {Gombár, Gyöngyi and Ungor, Ditta Anita and Szatmári, István and Juhász, Ádám and Csapó, Edit},
	doi = {10.3390/nano14050434},
	journal-iso = {NANOMATERIALS-BASEL},
	journal = {NANOMATERIALS},
	volume = {14},
	unique-id = {34689790},
	abstract = {Sub-nanometer-sized gold nanoclusters (Au NCs) were prepared via the spontaneous reduction of [AuCl4]−- ions with a hydroxamate derivative of L-tryptophan (Trp) natural amino acid (TrpHA). The prepared TrpHA-Au NCs possess intense blue emission (λem = 470 nm; λex = 380 nm) with a 2.13% absolute quantum yield and 1.47 ns average lifetime. The Trp-stabilized noble metal NCs are excellent metal ion sensors for Fe3+, but in this work, we highlighted that the incorporation of the hydroxamate functional group with an excellent metal ion binding capability can tune the selectivity and sensitivity of these NCs, which is a promising way to design novel strategies for the detection of other metal ions as well. Moreover, their simultaneous identification can also be realized. By decreasing the sensitivity of our nano-sensor for Fe3+ (limit of detection (LOD) ~11 µM), it was clearly demonstrated that the selectivity for Cu2+-ions can be significantly increased (LOD = 3.16 µM) in an acidic (pH = 3–4) condition. The surface-bounded TrpHA molecules can coordinate the Cu2+ confirmed by thermodynamic data, which strongly generates the linking of the NCs via the Cu2+ ions in acidic pH, and a parallel fluorescence quenching occurs. In the case of Fe3+, the degree of quenching strongly depends on the metal ion concentration, and it only occurs when the NCs are not able to bind more Fe3+ (~10 µM) on the surface, causing the NCs’ aggregation.},
	year = {2024},
	eissn = {2079-4991},
	orcid-numbers = {Ungor, Ditta Anita/0000-0002-7659-0428; Szatmári, István/0000-0002-8571-5229; Juhász, Ádám/0000-0003-0033-7968; Csapó, Edit/0000-0002-6980-9524}
}

@article{MTMT:34682913,
	title = {Enhancing the hydrophilicity of poly(lactic-co-glycolic acid) with serum albumin by creating colloidal drug carriers},
	url = {https://m2.mtmt.hu/api/publication/34682913},
	author = {Kovács, Nikolett Alexandra and Varga, Norbert and Bogner, József and Juhász, Ádám and Csapó, Edit},
	doi = {10.1016/j.molliq.2024.124271},
	journal-iso = {J MOL LIQ},
	journal = {JOURNAL OF MOLECULAR LIQUIDS},
	volume = {398},
	unique-id = {34682913},
	issn = {0167-7322},
	year = {2024},
	eissn = {1873-3166},
	orcid-numbers = {Varga, Norbert/0000-0002-9667-6608; Juhász, Ádám/0000-0003-0033-7968; Csapó, Edit/0000-0002-6980-9524}
}

@article{MTMT:34406348,
	title = {Thermodynamic Characterization of the Interaction of Biofunctionalized Gold Nanoclusters with Serum Albumin Using Two- and Three-Dimensional Methods},
	url = {https://m2.mtmt.hu/api/publication/34406348},
	author = {Juhász, Ádám and Gombár, Gyöngyi and F. Várkonyi, Egon and Wojnicki, Marek and Ungor, Ditta Anita and Csapó, Edit},
	doi = {10.3390/ijms242316760},
	journal-iso = {INT J MOL SCI},
	journal = {INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES},
	volume = {24},
	unique-id = {34406348},
	issn = {1661-6596},
	abstract = {Fluorescent gold nanoclusters have been successfully used as fluorescent markers for imaging of cells and tissues, and their potential role in drug delivery monitoring is coming to the fore. In addition, the development of biosensors using structure-tunable fluorescent nanoclusters is also a prominent research field. In the case of these sensor applications, the typical goal is the selective identification of, e.g., metal ions, small molecules having neuroactive or antioxidant effects, or proteins. During these application-oriented developments, in general, there is not enough time to systematically examine the interaction between nanoclusters and relevant biomolecules/proteins from a thermodynamic viewpoint. In this way, the primary motivation of this article is to carry out a series of tests to partially fill this scientific gap. Besides the well-known fluorescent probes, the mentioned interactions were investigated using such unique measurement methods as surface plasmon resonance (SPR) and isothermal titration calorimetry (ITC). These two-dimensional (at the solid/liquid interface) and three-dimensional (in the bulk phase) measuring techniques provide a unique opportunity for the thermodynamic characterization of the interaction between different gold nanoclusters containing various surface functionalizing ligands and bovine serum albumin (BSA).},
	year = {2023},
	eissn = {1422-0067},
	orcid-numbers = {Juhász, Ádám/0000-0003-0033-7968; Wojnicki, Marek/0000-0002-1387-0000; Ungor, Ditta Anita/0000-0002-7659-0428; Csapó, Edit/0000-0002-6980-9524}
}

@article{MTMT:34146936,
	title = {Lipid-Based Nanocarriers for Delivery of Neuroprotective Kynurenic Acid: Preparation, Characterization, and BBB Transport},
	url = {https://m2.mtmt.hu/api/publication/34146936},
	author = {Juhász, Ádám and Ungor, Ditta Anita and Varga, Norbert and Katona, Gábor and Balogh, György Tibor and Csapó, Edit},
	doi = {10.3390/ijms241814251},
	journal-iso = {INT J MOL SCI},
	journal = {INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES},
	volume = {24},
	unique-id = {34146936},
	issn = {1661-6596},
	abstract = {Encapsulation possibilities of an extensively investigated neuroprotective drug (kynurenic acid, KYNA) are studied via lipid-based nanocarriers to increase the blood–brain barrier (BBB) specific permeability. The outcomes of various preparation conditions such as stirring and sonication time, concentration of the lipid carriers and the drug, and the drug-to-lipid ratio are examined. Considering the experimentally determined encapsulation efficiency, hydrodynamic diameter, and ζ-potential values, the initial lipid and drug concentration as well as the stirring and sonication time of the preparation were optimized. The average hydrodynamic diameter of the prepared asolectin-(LIP) and water-soluble lipopolymer (WSLP)-based liposomes was found to be ca. 25 and 60 nm under physiological conditions. The physicochemical characterization of the colloidal carriers proves that the preparation of the drug-loaded liposomes was a successful process, and secondary interactions were indicated between the drug molecule and the polymer residues around the WSLP membrane. Dissolution profiles of the active molecule under physiological conditions were registered, and the release of the unformulated and encapsulated drug is very similar. In addition to this outcome, the in vitro polar brain lipid extract (porcine)-based permeability test proved the achievement of two- or fourfold higher BBB specific penetration and lipid membrane retention for KYNA in the liposomal carriers relative to the unformatted drug.},
	year = {2023},
	eissn = {1422-0067},
	orcid-numbers = {Juhász, Ádám/0000-0003-0033-7968; Ungor, Ditta Anita/0000-0002-7659-0428; Varga, Norbert/0000-0002-9667-6608; Katona, Gábor/0000-0003-1564-4813; Balogh, György Tibor/0000-0003-3347-1880; Csapó, Edit/0000-0002-6980-9524}
}

@article{MTMT:34041654,
	title = {The Effect of Concentration, Temperature, and pH on the Formation of Hyaluronic Acid–Surfactant Nanohydrogels},
	url = {https://m2.mtmt.hu/api/publication/34041654},
	author = {Seres, László and Csapó, Edit and Varga, Norbert and Juhász, Ádám},
	doi = {10.3390/gels9070529},
	journal-iso = {GELS-BASEL},
	journal = {GELS (BASEL)},
	volume = {9},
	unique-id = {34041654},
	abstract = {The assembly of colloidal hyaluronic acid (HyA, as a polysaccharide) based hydrogel particles in an aqueous medium is characterized in the present paper, with an emphasis on the particular case of nanohydrogels formed by surfactant-neutralized polysaccharide networks. The structural changes and particle formation process of polysaccharide- and cationic-surfactant-containing systems were induced by the charge neutralization ability and the hydrophobic interactions of cetyltrimethylammonium bromide (CTAB) under different conditions. Based on the rheological, light scattering, ζ-potential, turbidity, and charge titration measurements, it can be concluded that the preparation of the HyA-CTAB particles can be greatly controlled. The results indicate that more available negative charges can be detected on the polymer chain at smaller initial amounts of HyA (cHyA < 0.10 mg/mL), where a molecular solution can be formed. The change in the pH has a negligible effect on the formation process (particle aggregation appears at nCTAB/nHyA,monomer~1.0 in every case), while the temperature dependence of the critical micelle concentration (c.m.c.) of CTAB determines the complete neutralization of the forming nanohydrogels. The results of our measurements confirm that after the appearance of stable colloidal particles, a structural change and aggregation of the polymer particles take place, and finally the complete charge neutralization of the system occurs.},
	year = {2023},
	eissn = {2310-2861},
	orcid-numbers = {Csapó, Edit/0000-0002-6980-9524; Varga, Norbert/0000-0002-9667-6608; Juhász, Ádám/0000-0003-0033-7968}
}

@article{MTMT:33990098,
	title = {Effect of salinity on solution properties of a partially hydrolyzed polyacrylamide},
	url = {https://m2.mtmt.hu/api/publication/33990098},
	author = {Árok, Zsófia and Sáringer, Szilárd and Takács, Dóra and Bretz, Coline and Juhász, Ádám and Szilágyi, István},
	doi = {10.1016/j.molliq.2023.122192},
	journal-iso = {J MOL LIQ},
	journal = {JOURNAL OF MOLECULAR LIQUIDS},
	volume = {384},
	unique-id = {33990098},
	issn = {0167-7322},
	year = {2023},
	eissn = {1873-3166},
	orcid-numbers = {Sáringer, Szilárd/0000-0002-1906-8094; Juhász, Ádám/0000-0003-0033-7968; Szilágyi, István/0000-0001-7289-0979}
}

@article{MTMT:33784094,
	title = {Core-Shell Structured PLGA Particles Having Highly Controllable Ketoprofen Drug Release},
	url = {https://m2.mtmt.hu/api/publication/33784094},
	author = {Varga, Norbert and Bélteki, Rita and Juhász, Ádám and Csapó, Edit},
	doi = {10.3390/pharmaceutics15051355},
	journal-iso = {PHARMACEUTICS},
	journal = {PHARMACEUTICS},
	volume = {15},
	unique-id = {33784094},
	issn = {1999-4923},
	abstract = {The non-steroid anti-inflammatory drug ketoprofen (KP) as a model molecule is encapsulated in different poly(lactide-co-glycolide) (PLGA) nanostructured particles, using Tween20 (TWEEN) and Pluronic F127 (PLUR) as stabilizers to demonstrate the design of a biocompatible colloidal carrier particles with highly controllable drug release feature. Based on TEM images the formation of well-defined core-shell structure is highly favorable using nanoprecipitation method. Stabile polymer-based colloids with ~200–210 nm hydrodynamic diameter can be formed by successful optimization of the KP concentration with the right choice of stabilizer. Encapsulation efficiency (EE%) of 14–18% can be achieved. We clearly confirmed that the molecular weight of the stabilizer thus its structure greatly controls the drug release from the PLGA carrier particles. It can be determined that ~20% and ~70% retention is available with the use of PLUR and TWEEN, respectively. This measurable difference can be explained by the fact that the non-ionic PLUR polymer provides a steric stabilization of the carrier particles in the form of a loose shell, while the adsorption of the non-ionic biocompatible TWEEN surfactant results in a more compact and well-ordered shell around the PLGA particles. In addition, the release property can be further tuned by decreasing the hydrophilicity of PLGA by changing the monomer ratio in the range of ~20–60% (PLUR) and 70–90% (TWEEN).},
	year = {2023},
	eissn = {1999-4923},
	orcid-numbers = {Varga, Norbert/0000-0002-9667-6608; Juhász, Ádám/0000-0003-0033-7968; Csapó, Edit/0000-0002-6980-9524}
}

@article{MTMT:33733011,
	title = {Promising Bioactivity of Vitamin B1-Au Nanocluster: Structure, Enhanced Antioxidant Behavior, and Serum Protein Interaction},
	url = {https://m2.mtmt.hu/api/publication/33733011},
	author = {Ungor, Ditta Anita and Gombár, Gyöngyi and Juhász, Ádám and Samu, Gergely Ferenc and Csapó, Edit},
	doi = {10.3390/antiox12040874},
	journal-iso = {ANTIOXIDANTS-BASEL},
	journal = {ANTIOXIDANTS},
	volume = {12},
	unique-id = {33733011},
	abstract = {In the current work, we first present a simple synthesis method for the preparation of novel Vitamin-B1-stabilized few-atomic gold nanoclusters with few atomic layers. The formed nanostructure contains ca. eight Au atoms and shows intensive blue emissions at 450 nm. The absolute quantum yield is 3%. The average lifetime is in the nanosecond range and three main components are separated and assigned to the metal–metal and ligand–metal charge transfers. Based on the structural characterization, the formed clusters contain Au in zero oxidation state, and Vitamin B1 stabilizes the metal cores via the coordination of pyrimidine-N. The antioxidant property of the Au nanoclusters is more prominent than that of the pure Vitamin B1, which is confirmed by two different colorimetric assays. For the investigation into their potential bioactivity, interactions with bovine serum albumin were carried out and quantified. The determined stoichiometry indicates a self-catalyzed binding, which is almost the same value based on the fluorometric and calorimetric measurements. The calculated thermodynamic parameters verify the spontaneous bond of the clusters along the protein chain by hydrogen bonds and electrostatic interactions.},
	year = {2023},
	eissn = {2076-3921},
	orcid-numbers = {Ungor, Ditta Anita/0000-0002-7659-0428; Juhász, Ádám/0000-0003-0033-7968; Samu, Gergely Ferenc/0000-0002-3239-9154; Csapó, Edit/0000-0002-6980-9524}
}

@article{MTMT:33257970,
	title = {Flow-driven synthesis of calcium phosphate-calcium alginate hybrid chemical gardens},
	url = {https://m2.mtmt.hu/api/publication/33257970},
	author = {Zahorán, Réka and Kumar, Pawan and Juhász, Ádám and Horváth, Dezső and Tóth, Ágota},
	doi = {10.1039/d2sm01063a},
	journal-iso = {SOFT MATTER},
	journal = {SOFT MATTER},
	volume = {18},
	unique-id = {33257970},
	issn = {1744-683X},
	abstract = {Systems far-from-equilibrium self-assemble into spatiotemporal structures. Here, we report on the formation of calcium alginate gardens along with their inorganic hybrids when a sodium alginate solution containing sodium phosphate in various compositions is injected into a calcium chloride reservoir. The viscoelastic properties of the membranes developed are controlled by the injection rate, while their thickness by the amount of sodium phosphate besides diffusion. Inorganic hybrid membranes with constant thickness are synthesized in the presence of a sufficient amount of sodium phosphate. The electrochemical characterization of the membranes suggests that the driving force is the pH-gradient developing along the two sides; hence, the cell potential can be controlled by the addition of alkaline sodium phosphate into the sodium alginate solution.},
	keywords = {GENERATION; Chemistry, Physical; ARCHITECTURES; Electricity; Materials Science, Multidisciplinary; Physics, Multidisciplinary; SILICA TUBES},
	year = {2022},
	eissn = {1744-6848},
	pages = {8157-8164},
	orcid-numbers = {Kumar, Pawan/0000-0002-3531-2077; Juhász, Ádám/0000-0003-0033-7968; Horváth, Dezső/0000-0003-3852-6879; Tóth, Ágota/0000-0001-8254-6354}
}