@article{MTMT:3399728, title = {Antiproliferative and Antimicrobial Activities of Selected Bryophytes}, url = {https://m2.mtmt.hu/api/publication/3399728}, author = {Vollár, Martin and Gyovai, András and Szűcs, Péter and Zupkó, István and Marschall, Marianna and Csupor-Löffler, Boglárka and Bérdi, Péter and Vecsernyés, A and Csorba, Attila and Liktor-Busa, Erika and Zsoldiné Urbán, Edit and Csupor, Dezső}, doi = {10.3390/molecules23071520}, journal-iso = {MOLECULES}, journal = {MOLECULES}, volume = {23}, unique-id = {3399728}, issn = {1420-3049}, year = {2018}, eissn = {1420-3049}, orcid-numbers = {Gyovai, András/0000-0003-2316-2160; Zupkó, István/0000-0003-3243-5300; Marschall, Marianna/0009-0009-8060-9767; Csorba, Attila/0000-0002-4032-1605; Liktor-Busa, Erika/0000-0002-0495-8721; Zsoldiné Urbán, Edit/0000-0002-9602-7552; Csupor, Dezső/0000-0002-4088-3333} } @article{MTMT:3307270, title = {Phytochemical and pharmacological investigation of Spiraea chamaedryfolia: a contribution to the chemotaxonomy of Spiraea genus}, url = {https://m2.mtmt.hu/api/publication/3307270}, author = {Kiss, Tivadar and Cank, Kristóf Bence and Orbán-Gyapai, Orsolya and Liktor-Busa, Erika and Zomborszki, Zoltán Péter and Santa, Rutkovska and Irēna, Pučka and Anikó, Németh and Csupor, Dezső}, doi = {10.1186/s13104-017-3013-y}, journal-iso = {BMC RES NOTES}, journal = {BMC RESEARCH NOTES}, volume = {10}, unique-id = {3307270}, issn = {1756-0500}, year = {2017}, orcid-numbers = {Kiss, Tivadar/0000-0003-3538-377X; Liktor-Busa, Erika/0000-0002-0495-8721; Zomborszki, Zoltán Péter/0000-0002-7412-9793; Csupor, Dezső/0000-0002-4088-3333} } @article{MTMT:3287856, title = {Hungarian mushrooms as untapped source of natural products: from screening studies to biologically active metabolites}, url = {https://m2.mtmt.hu/api/publication/3287856}, author = {Ványolós, Attila and Kovács, Bernadett and Béni, Zoltán and Dékány, M and Krámos, B and Liktor-Busa, Erika and Zomborszki, Zoltán Péter and Zupkó, István and Hohmann, Judit}, doi = {10.1055/s-0037-1608106}, journal-iso = {PLANTA MEDICA INT OPEN}, journal = {PLANTA MEDICA INTERNATIONAL OPEN}, volume = {4}, unique-id = {3287856}, year = {2017}, eissn = {2509-6656}, orcid-numbers = {Ványolós, Attila/0000-0002-4710-0004; Béni, Zoltán/0000-0002-1275-4155; Liktor-Busa, Erika/0000-0002-0495-8721; Zomborszki, Zoltán Péter/0000-0002-7412-9793; Zupkó, István/0000-0003-3243-5300; Hohmann, Judit/0000-0002-2887-6392} } @article{MTMT:3247431, title = {Investigation of Antimicrobial, Antioxidant, and Xanthine Oxidase−Inhibitory Activities of Phellinus (Agaricomycetes) Mushroom Species Native to Central Europe}, url = {https://m2.mtmt.hu/api/publication/3247431}, author = {Kovács, Bernadett and Zomborszki, Zoltán Péter and Orbán-Gyapai, Orsolya and Csupor-Löffler, Boglárka and Liktor-Busa, Erika and Lázár, Andrea and Papp, Viktor and Zsoldiné Urbán, Edit and Hohmann, Judit and Ványolós, Attila}, doi = {10.1615/IntJMedMushrooms.v19.i5.10}, journal-iso = {INT J MED MUSHROOM}, journal = {INTERNATIONAL JOURNAL OF MEDICINAL MUSHROOMS}, volume = {19}, unique-id = {3247431}, issn = {1521-9437}, year = {2017}, eissn = {1940-4344}, pages = {387-394}, orcid-numbers = {Zomborszki, Zoltán Péter/0000-0002-7412-9793; Liktor-Busa, Erika/0000-0002-0495-8721; Zsoldiné Urbán, Edit/0000-0002-9602-7552; Hohmann, Judit/0000-0002-2887-6392; Ványolós, Attila/0000-0002-4710-0004} } @{MTMT:3245171, title = {Phytochemical and pharmacological investigation of Spiraea chamaedryfolia}, url = {https://m2.mtmt.hu/api/publication/3245171}, author = {Cank, Kristóf Bence and Kiss, Tivadar and Orbán-Gyapai, Orsolya and Liktor-Busa, Erika and Santa, Rutkovska and Irēna, Pučka and Csupor, Dezső}, booktitle = {Trends in Natural Product Research - PSE Young Scientists’ Meeting Lille 2017. Natural Products in Health, Agro-food and Cosmetics: Abstracts of the Phytochemical Society of Europe}, unique-id = {3245171}, abstract = {Diterpene alkaloids are characteristic compounds for the Ranunculaceae family and for some other very few plant taxa. The high biological activity of these compounds depends on the skeleton type and the substitution pattern1. Poorly examined diterpene alkaloid-containing taxa might be promising sources of new compounds with pharmacological activities. The genus Spiraea is one of the unique and very few taxa that contain diterpene alkaloids2. The aim of our present work was the identification of a new diterpene alkaloid-containing Spiraea species. Methanolic, acidic and alkaline extracts were prepared from seven Spiraea species (S. crenata, S. media, S. salicifolia, S. nipponica, S. vanhouttei, S. billardii and S. chamaedryfolia) and their diterpene alkaloid content was examined by means of TLC by applying highly selective alkaloid detection. The multistep extraction of diterpene alkaloids was performed and the extracts were subjected to in vitro antibacterial and xanthine oxidase inhibitory activity.Our research group detected the presence of diterpene alkaloids in S. chamaedryfolia for the first time. For alkaloid extraction, a multistep method was developed. The neutral, acidic and alkaline extracts of the roots exerted noteworthy xanthine oxidase inhibitory activity (>70%). The extracts exhibited antibacterial activity in vitro against Staphylococcus aureus, Bacillus subtilis, Moraxella catarrhalis, Streptococcus pneumoniae and methicillin-resistant Staphylococcus aureus (MRSA). Based on these results the continuation of the phytochemical work seems promising with the aim of isolation of pure compounds and the characterization of the compounds responsible for the antibacterial and xanthine oxidase inhibitory activity.}, year = {2017}, pages = {123-123}, orcid-numbers = {Kiss, Tivadar/0000-0003-3538-377X; Liktor-Busa, Erika/0000-0002-0495-8721; Csupor, Dezső/0000-0002-4088-3333} } @article{MTMT:3201412, title = {Antibacterial screening of Rumex species native to the Carpathian Basin and bioactivity-guided isolation of compounds from Rumex aquaticus}, url = {https://m2.mtmt.hu/api/publication/3201412}, author = {Orbán-Gyapai, Orsolya and Liktor-Busa, Erika and Kúsz, Norbert and Stefkó, Dóra and Zsoldiné Urbán, Edit and Hohmann, Judit and Vasas, Andrea}, doi = {10.1016/j.fitote.2017.03.009}, journal-iso = {FITOTERAPIA}, journal = {FITOTERAPIA}, volume = {118}, unique-id = {3201412}, issn = {0367-326X}, abstract = {Abstract Plants belonging to the genus Rumex (family Polygonaceae) are used worldwide in traditional medicine for the treatment of various diseases caused by different microorganisms (e.g. bacteria-related dermatologic conditions, dysentery and enteritis). The present study focused on the antibacterial screening of Rumex species native to the Carpathian Basin, and isolation of compounds from one of the most efficient species, Rumex aquaticus. The antibacterial effects of n-hexane, chloroform and aqueous fractions of methanol extracts prepared from different parts of 14 Rumex species (R. acetosella, R. acetosa, R. alpinus, R. aquaticus, R. conglomeratus, R. crispus, R. hydrolapathum, R. obtusifolius subsp. obtusifolius, R. obtusifolius subsp. subalpinus, R. patientia, R. pulcher, R. scutatus, R. stenophyllus and R. thyrsiflorus) were investigated against Staphylococcus epidermidis, S. aureus, MRSA, Bacillus subtilis, Moraxella catarrhalis, Streptococcus pyogenes, S. pneumoniae, S. agalactiae, Pseudomonas aeruginosa, Escherichia coli and Klebsiella pneumoniae using the disc diffusion method. Mainly the n-hexane and chloroform extracts prepared from the roots of the plants displayed high antibacterial activity (inhibition zones > 15 mm) against one or more bacterial strains. The highly active extracts of the aerial part and root of R. aquaticus were subjected to a multistep separation procedure. 19 Compounds, among them naphthalenes (musizin, and its glucoside, torachrysone-glucoside, 2-methoxystypandrone), anthraquinones (emodin, chrysophanol, physcion, citreorosein, chrysophanol-8-O-glucoside), flavonoids (quercetin, quercetin-3,3′-dimethylether, isokaempferide, quercetin 3-O-arabinoside, quercetin 3-O-galactoside, catechin), stilbenes (resveratrol, piceid), and 1-stearoylglycerol were isolated from the plant. The antibacterial activities of isolated compounds were determined, and it was observed that especially naphthalenes exerted remarkable antibacterial effects against several bacterial strains.}, keywords = {antibacterial activity; Rumex aquaticus; Polygonaceae; Rumex species; Musizin; 2-methoxystypandrone}, year = {2017}, eissn = {1873-6971}, pages = {101-106}, orcid-numbers = {Liktor-Busa, Erika/0000-0002-0495-8721; Kúsz, Norbert/0000-0002-9973-6442; Stefkó, Dóra/0000-0002-5435-546X; Zsoldiné Urbán, Edit/0000-0002-9602-7552; Hohmann, Judit/0000-0002-2887-6392; Vasas, Andrea/0000-0002-1818-7702} } @article{MTMT:3143290, title = {Phenanthrenes from Juncus inflexus with Antimicrobial Activity against Methicillin-Resistant Staphylococcus aureus}, url = {https://m2.mtmt.hu/api/publication/3143290}, author = {Tóth, Barbara and Liktor-Busa, Erika and Kúsz, Norbert and Szappanos, Ádám and Mándi, Attila and Kurtán, Tibor and Zsoldiné Urbán, Edit and Hohmann, Judit and Fang-Rong, Chang and Vasas, Andrea}, doi = {10.1021/acs.jnatprod.6b00581}, journal-iso = {J NAT PROD}, journal = {JOURNAL OF NATURAL PRODUCTS}, volume = {79}, unique-id = {3143290}, issn = {0163-3864}, abstract = {The present study has focused on an investigation of the antibacterial effects of Juncus inflexus and the isolation and identification of its active compounds. Eleven phenanthrenes were isolated from a methanolic extract of the roots. Four compounds (jinflexins A−D, 1−4) are new natural products, while seven phenanthrenes [juncuenins A (5), B (6), and D (8), juncusol (7), dehydrojuncuenins A (9) and B (11), and dehydrojuncusol (10)] were isolated for the first time from the plant. Jinflexin D (4) is a dimer with an unprecedented heptacyclic ring system. The absolute configurations of the new compounds were determined by TDDFT-ECD calculations, and their enantiomeric purity was checked by chiral HPLC analysis. Extracts of different polarity (n-hexane, dichloromethane, and ethyl acetate) were evaluated for their antimicrobial effects against methicillin-resistant Staphylococcus aureus, extended-spectrum β-lactamase (ESBL)-producing Citrobacter freundii, Escherichia coli, Enterobacter cloacae, Klebsiella pneumoniae, multiresistant Acinetobacter baumannii, and Pseudomonas aeruginosa. The MIC values of the isolated compounds were determined by a microdilution method. Jinflexin B (2), juncusol (7), juncuenin D (8), and dehydrojuncuenin B (11) showed significant activity (MIC value range 12.5−100 μg/mL) against MRSA strains.}, year = {2016}, eissn = {1520-6025}, pages = {2814-2823}, orcid-numbers = {Tóth, Barbara/0000-0002-6086-8819; Liktor-Busa, Erika/0000-0002-0495-8721; Kúsz, Norbert/0000-0002-9973-6442; Zsoldiné Urbán, Edit/0000-0002-9602-7552; Hohmann, Judit/0000-0002-2887-6392; Vasas, Andrea/0000-0002-1818-7702} } @article{MTMT:3121418, title = {Antibacterial screening of Juncaceae species native to the Carpathian Basin against resistant strains and LC-MS investigation of phenanthrenes responsible for the effect}, url = {https://m2.mtmt.hu/api/publication/3121418}, author = {Tóth, Barbara and Liktor-Busa, Erika and Zsoldiné Urbán, Edit and Csorba, Attila and Jakab, Gusztáv and Hohmann, Judit and Vasas, Andrea}, doi = {10.1016/j.fitote.2016.09.024}, journal-iso = {FITOTERAPIA}, journal = {FITOTERAPIA}, volume = {115}, unique-id = {3121418}, issn = {0367-326X}, year = {2016}, eissn = {1873-6971}, pages = {69-73}, orcid-numbers = {Tóth, Barbara/0000-0002-6086-8819; Liktor-Busa, Erika/0000-0002-0495-8721; Zsoldiné Urbán, Edit/0000-0002-9602-7552; Csorba, Attila/0000-0002-4032-1605; Jakab, Gusztáv/0000-0002-2569-5967; Hohmann, Judit/0000-0002-2887-6392; Vasas, Andrea/0000-0002-1818-7702} } @CONFERENCE{MTMT:3082834, title = {Juncaceae fajok biológiailag aktív vegyületeinek izolálása és szerkezet-meghatározása}, url = {https://m2.mtmt.hu/api/publication/3082834}, author = {Tóth, Barbara and Kúsz, Norbert and Liktor-Busa, Erika and Zsoldiné Urbán, Edit and Hunyadi, Attila and Chang, Fang-Rong and Kurtán, Tibor and Hohmann, Judit and Vasas, Andrea}, booktitle = {Fiatal Gyógynövénykutatók Fóruma: a Magyar Gyógyszerésztudományi Társaság Gyógynövény Szakosztályának tudományos konferenciája}, unique-id = {3082834}, year = {2016}, pages = {6-6}, orcid-numbers = {Tóth, Barbara/0000-0002-6086-8819; Kúsz, Norbert/0000-0002-9973-6442; Liktor-Busa, Erika/0000-0002-0495-8721; Zsoldiné Urbán, Edit/0000-0002-9602-7552; Hunyadi, Attila/0000-0003-0074-3472; Hohmann, Judit/0000-0002-2887-6392; Vasas, Andrea/0000-0002-1818-7702} } @article{MTMT:3058452, title = {Investigation of Hungarian mushrooms for antibacterial activity and synergistic effects with standard antibiotics against resistant bacterial strains}, url = {https://m2.mtmt.hu/api/publication/3058452}, author = {Liktor-Busa, Erika and Kovács, Bernadett and Zsoldiné Urbán, Edit and Hohmann, Judit and Ványolós, Attila}, doi = {10.1111/lam.12576}, journal-iso = {LETT APPL MICROBIOL}, journal = {LETTERS IN APPLIED MICROBIOLOGY}, volume = {62}, unique-id = {3058452}, issn = {0266-8254}, keywords = {antibacterial activity; Methicillin-resistant Staphylococcus aureus; Synergism; Rhodocybe popinalis; Tapinella atrotomentosa; Fistulina hepatica; mushroom extracts}, year = {2016}, eissn = {1472-765X}, pages = {437-443}, orcid-numbers = {Liktor-Busa, Erika/0000-0002-0495-8721; Zsoldiné Urbán, Edit/0000-0002-9602-7552; Hohmann, Judit/0000-0002-2887-6392; Ványolós, Attila/0000-0002-4710-0004} }