@mastersthesis{MTMT:32829435, title = {Dissolution improvement of albendazole by reconstitutable dry nanosuspension formulation}, url = {https://m2.mtmt.hu/api/publication/32829435}, author = {Fülöp, Viktor}, doi = {10.14753/SE.2021.2466}, unique-id = {32829435}, year = {2021}, orcid-numbers = {Fülöp, Viktor/0000-0002-6046-1955} } @article{MTMT:32496819, title = {Transformation of Cilostazole Nanosuspension into Nanocrystal to Increase the Product Stability and Dissolution Rate}, url = {https://m2.mtmt.hu/api/publication/32496819}, author = {Isameddin, Aghrbi and Fülöp, Viktor and Jakab, Géza and Kállai-Szabó, Nikolett and Bertalanné Balogh, Emese and Antal, István}, doi = {10.33892/aph.2021.91.165-166}, journal-iso = {ACTA PHARM HUNG}, journal = {ACTA PHARMACEUTICA HUNGARICA}, volume = {91}, unique-id = {32496819}, issn = {0001-6659}, year = {2021}, eissn = {1587-1495}, pages = {165-166}, orcid-numbers = {Fülöp, Viktor/0000-0002-6046-1955; Jakab, Géza/0000-0002-8103-774X; Kállai-Szabó, Nikolett/0000-0002-8164-3993; Bertalanné Balogh, Emese/0000-0002-1127-3923; Antal, István/0000-0002-5434-201X} } @article{MTMT:31911988, title = {Evaluation of Biodegradable PVA-Based 3D Printed Carriers during Dissolution}, url = {https://m2.mtmt.hu/api/publication/31911988}, author = {Basa, Bálint and Jakab, Géza and Kállai-Szabó, Nikolett and Borbás, Bence and Fülöp, Viktor and Bertalanné Balogh, Emese and Antal, István}, doi = {10.3390/ma14061350}, journal-iso = {MATERIALS}, journal = {MATERIALS}, volume = {14}, unique-id = {31911988}, year = {2021}, eissn = {1996-1944}, orcid-numbers = {Basa, Bálint/0000-0003-4546-1727; Jakab, Géza/0000-0002-8103-774X; Kállai-Szabó, Nikolett/0000-0002-8164-3993; Borbás, Bence/0000-0002-4892-4347; Fülöp, Viktor/0000-0002-6046-1955; Bertalanné Balogh, Emese/0000-0002-1127-3923; Antal, István/0000-0002-5434-201X} } @article{MTMT:31793659, title = {Comparative Evaluation of Pellet Cushioning Agents by Various Imaging Techniques and Dissolution Studies}, url = {https://m2.mtmt.hu/api/publication/31793659}, author = {Sántha, Konrád and Kállai-Szabó, Nikolett and Fülöp, Viktor and Jakab, Géza and Gordon, Péter and Kállai-Szabó, Barnabás and Bertalanné Balogh, Emese and Antal, István}, doi = {10.1208/s12249-020-01902-x}, journal-iso = {AAPS PHARMSCITECH}, journal = {AAPS PHARMSCITECH}, volume = {22}, unique-id = {31793659}, issn = {1530-9932}, abstract = {Most of the commercially available pharmaceutical products for oral administration route are marketed in the tablet dosage forms. However, compression of multiparticulate systems is a challenge for the pharmaceutical research and industry, especially if the individual unit is a coated particle, as the release of the active ingredient depends on the integrity of the coating. In the present study, polymer-coated pellets tableted with different types of excipients (powder, granules, pellets) then were investigated by various tablet-destructive (microscopic) and tablet non-destructive (microfocus X-ray; microCT) imaging methods. The information obtained from the independent evaluation of the in vitro drug release profiles model is confirmed by the results obtained by image analysis, regardless of whether X-ray or stereomicroscopic images of the coated, tableted pellets were used for image analysis. The results of this study show that the novel easy-to-use, fast, and non-destructive MFX method is a good alternative to the already used microscopic image analysis methods regarding the characterization of particulates, compressed into tablets.}, year = {2021}, eissn = {1530-9932}, orcid-numbers = {Sántha, Konrád/0000-0002-1483-5784; Kállai-Szabó, Nikolett/0000-0002-8164-3993; Fülöp, Viktor/0000-0002-6046-1955; Jakab, Géza/0000-0002-8103-774X; Kállai-Szabó, Barnabás/0000-0001-6259-4818; Bertalanné Balogh, Emese/0000-0002-1127-3923; Antal, István/0000-0002-5434-201X} } @article{MTMT:31641232, title = {Nanosuspension with improved saturated solubility and dissolution rate of cilostazol and effect of solidification on stability}, url = {https://m2.mtmt.hu/api/publication/31641232}, author = {Aghrbi, Isameddin and Fülöp, Viktor and Jakab, Géza and Kállai-Szabó, Nikolett and Bertalanné Balogh, Emese and Antal, István}, doi = {10.1016/j.jddst.2020.102165}, journal-iso = {J DRUG DELIV SCI TEC}, journal = {JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY}, volume = {61}, unique-id = {31641232}, issn = {1773-2247}, year = {2021}, eissn = {2588-8943}, orcid-numbers = {Fülöp, Viktor/0000-0002-6046-1955; Jakab, Géza/0000-0002-8103-774X; Kállai-Szabó, Nikolett/0000-0002-8164-3993; Bertalanné Balogh, Emese/0000-0002-1127-3923; Antal, István/0000-0002-5434-201X} } @article{MTMT:31389324, title = {Study on Optimization of Wet Milling Process for the Development of Albendazole Containing Nanosuspension with Improved Dissolution}, url = {https://m2.mtmt.hu/api/publication/31389324}, author = {Fülöp, Viktor and Jakab, Géza and Tóth, Bence and Bertalanné Balogh, Emese and Antal, István}, doi = {10.3311/PPch.15569}, journal-iso = {PERIOD POLYTECH CHEM ENG}, journal = {PERIODICA POLYTECHNICA-CHEMICAL ENGINEERING}, volume = {64}, unique-id = {31389324}, issn = {0324-5853}, abstract = {The main objective of this work was to show the potential of the optimization of top-down wet planetary bead milling process parameters (milling speed, process time and size of the milling medium) by Design Of Experiments (DOE) approach for the development of albendazole (ABZ) containing nanosuspension with improved dissolution. In addition, the influence of process parameters (capacity of milling container, applied volume of milling beads, size of the milling medium, milling speed, milling time) on ABZ polymorphic transition has also been investigated. The optimized, milled formula yielded ~ 145.39 times reduction in mean particle size (182.200 ± 1.3130 nm) compared to unmilled dispersion, which demonstrated 13.50 times gain in mean dissolution rate value compared to the unmilled dispersion in medium at pH = 1.2. No lag time values were observed in the dissolution kinetics of the nanosuspension in comparison with the unmilled samples. Moreover, maximal mean solubility value was also improved by 1.45 times compared to the unmilled suspension, in medium at pH = 6.8, supporting the significance of the Ostwald-Freundlich equation. Diffraction pattern comparisons have indicated a polymorphic transition of albendazole to Form II, which was more pronounced in smaller container at high milling speed values and prolonged operations}, year = {2020}, eissn = {1587-3765}, pages = {401-420}, orcid-numbers = {Fülöp, Viktor/0000-0002-6046-1955; Jakab, Géza/0000-0002-8103-774X; Bertalanné Balogh, Emese/0000-0002-1127-3923; Antal, István/0000-0002-5434-201X} } @CONFERENCE{MTMT:31176468, title = {Baicalin tartalmú gyógyszerhordozó rendszerek fejlesztése és formulálása}, url = {https://m2.mtmt.hu/api/publication/31176468}, author = {Jakab, Géza and Fülöp, Viktor and Bozó, Tamás and Bogdán, Dóra and Mazák, Károly and Turbucz, Béla and Kállai-Szabó, Nikolett and Bertalanné Balogh, Emese and Antal, István}, booktitle = {Gyógyszertechnológiai és Ipari Gyógyszerészeti Konferencia 2019}, unique-id = {31176468}, year = {2019}, pages = {EA17}, orcid-numbers = {Jakab, Géza/0000-0002-8103-774X; Fülöp, Viktor/0000-0002-6046-1955; Bogdán, Dóra/0000-0003-4455-8914; Turbucz, Béla/0000-0003-0321-2810; Kállai-Szabó, Nikolett/0000-0002-8164-3993; Bertalanné Balogh, Emese/0000-0002-1127-3923; Antal, István/0000-0002-5434-201X} } @CONFERENCE{MTMT:31176431, title = {3D nyomtatás alkalmazási lehetőségei betegközpontú hatóanyag-felszabadító rendszerek formulálásában}, url = {https://m2.mtmt.hu/api/publication/31176431}, author = {Basa, Bálint and Jakab, Géza and Fülöp, Viktor and Bertalanné Balogh, Emese and Antal, István}, booktitle = {Gyógyszertechnológiai és Ipari Gyógyszerészeti Konferencia 2019}, unique-id = {31176431}, year = {2019}, pages = {EA24}, orcid-numbers = {Basa, Bálint/0000-0003-4546-1727; Jakab, Géza/0000-0002-8103-774X; Fülöp, Viktor/0000-0002-6046-1955; Bertalanné Balogh, Emese/0000-0002-1127-3923; Antal, István/0000-0002-5434-201X} } @CONFERENCE{MTMT:31176327, title = {Nedves Őrlés hatása az albendazol polimorfiájára}, url = {https://m2.mtmt.hu/api/publication/31176327}, author = {Fülöp, Viktor and Jakab, Géza and Tóth, Bence and Bertalanné Balogh, Emese and Antal, István}, booktitle = {Gyógyszertechnológiai és Ipari Gyógyszerészeti Konferencia 2019}, unique-id = {31176327}, year = {2019}, pages = {P07}, orcid-numbers = {Fülöp, Viktor/0000-0002-6046-1955; Jakab, Géza/0000-0002-8103-774X; Bertalanné Balogh, Emese/0000-0002-1127-3923; Antal, István/0000-0002-5434-201X} } @misc{MTMT:30757355, title = {Biodegradable Nanoparticles for Pulmonary Delivery of Apigenin}, url = {https://m2.mtmt.hu/api/publication/30757355}, author = {Pápay, Zsófia Edit and Fülöp, Viktor and Bertalanné Balogh, Emese and Kósa, Annamária and Vági, Pál and Böddi, Béla and Klebovich, Imre and Antal, István}, unique-id = {30757355}, year = {2018}, orcid-numbers = {Pápay, Zsófia Edit/0000-0002-7653-1065; Fülöp, Viktor/0000-0002-6046-1955; Bertalanné Balogh, Emese/0000-0002-1127-3923; Kósa, Annamária/0000-0002-4629-7802; Vági, Pál/0000-0001-8999-4475; Böddi, Béla/0000-0003-3701-3625; Klebovich, Imre/0000-0003-1672-5172; Antal, István/0000-0002-5434-201X} }