@article{MTMT:34432072, title = {Az oxidatív stressz etiológiai szerepe a főbb szülészeti kórállapotok hátterében}, url = {https://m2.mtmt.hu/api/publication/34432072}, author = {Joó, József Gábor and Csatlós, Éva and Börzsönyi, Balázs and Demendi, Csaba and Kornya, László}, journal-iso = {MAGYAR NŐORVOSOK LAPJA}, journal = {MAGYAR NŐORVOSOK LAPJA}, volume = {86}, unique-id = {34432072}, issn = {0025-021X}, year = {2023}, pages = {314-320}, orcid-numbers = {Joó, József Gábor/0000-0001-9820-6514; Börzsönyi, Balázs/0000-0003-1095-0002; Demendi, Csaba/0000-0001-6469-5487} } @article{MTMT:34196772, title = {Disrupted Balance of the Oxidant–Antioxidant System in the Pathophysiology of Female Reproduction: Oxidative Stress and Adverse Pregnancy Outcomes}, url = {https://m2.mtmt.hu/api/publication/34196772}, author = {Joó, József Gábor and Sulyok, Endre and Bódis, József and Kornya, László}, doi = {10.3390/cimb45100511}, journal-iso = {CURR ISSUES MOL BIOL}, journal = {CURRENT ISSUES IN MOLECULAR BIOLOGY}, volume = {45}, unique-id = {34196772}, issn = {1467-3037}, abstract = {The significance of oxidative stress in the pathophysiology of male reproductive processes has been closely studied in the last two decades. Recently, it has become clear that oxidative stress can lead to numerous pathological conditions during female reproductive processes as well, contributing to the development of endometriosis, polycystic ovary syndrome and various forms of infertility. During pregnancy, physiological generation of reactive oxygen species (ROS) occurs in association with several developmental processes including oocyte maturation and implantation. An overproduction of ROS can lead to disturbances in fetal development and increases the risk for missed abortion, intrauterine growth restriction, pre-eclampsia, premature delivery and gestational diabetes. Our review focuses on the etiological role of the disrupted oxidant–antioxidant system during human gestation as it relates to adverse pregnancy outcomes.}, year = {2023}, eissn = {1467-3045}, pages = {8091-8111}, orcid-numbers = {Joó, József Gábor/0000-0001-9820-6514} } @article{MTMT:34141637, title = {Az oxidatív stressz szerepe a női reprodukcióban}, url = {https://m2.mtmt.hu/api/publication/34141637}, author = {Joó, József Gábor and Csatlós, Éva and Börzsönyi, Balázs and Demendi, Csaba and Kornya, László}, journal-iso = {MAGYAR NŐORVOSOK LAPJA}, journal = {MAGYAR NŐORVOSOK LAPJA}, volume = {86}, unique-id = {34141637}, issn = {0025-021X}, year = {2023}, pages = {207-213}, orcid-numbers = {Joó, József Gábor/0000-0001-9820-6514; Börzsönyi, Balázs/0000-0003-1095-0002; Demendi, Csaba/0000-0001-6469-5487} } @article{MTMT:31822988, title = {Improved Inhibitory and Absorption, Distribution, Metabolism, Excretion, and Toxicology (ADMET) Properties of Blebbistatin Derivatives Indicate That Blebbistatin Scaffold Is Ideal for drug Development Targeting Myosin-2}, url = {https://m2.mtmt.hu/api/publication/31822988}, author = {Gyimesi, Máté and Rauscher, Anna Á. and Suthar, Sharad Kumar and Hamow, Kamirán Áron and Oravecz, Kinga and Lőrincz, István and Borhegyi, Zsolt and Déri, Máté Tamás and Kiss, Ádám F. and Monostory, Katalin and Szabó, Pál Tamás and Nag, Suman and Tomasic, Ivan and Krans, Jacob and Tierney, Patrick J. and Kovács, Mihály and Kornya, László and Málnási Csizmadia, András}, doi = {10.1124/jpet.120.000167}, journal-iso = {J PHARMACOL EXP THER}, journal = {JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS}, volume = {376}, unique-id = {31822988}, issn = {0022-3565}, year = {2021}, eissn = {1521-0103}, pages = {358-373}, orcid-numbers = {Hamow, Kamirán Áron/0000-0002-7089-1078; Déri, Máté Tamás/0000-0002-8261-5230; Szabó, Pál Tamás/0000-0003-2260-4641; Kovács, Mihály/0000-0002-1200-4741; Málnási Csizmadia, András/0000-0002-2430-8398} } @article{MTMT:31733407, title = {Multiple SARS-CoV-2 Introductions Shaped the Early Outbreak in Central Eastern Europe: Comparing Hungarian Data to a Worldwide Sequence Data-Matrix}, url = {https://m2.mtmt.hu/api/publication/31733407}, author = {Kemenesi, Gábor and Zeghbib, Safia and Somogyi, Balázs Antal and Tóth, Gábor Endre and Bányai, Krisztián and Solymosi, Norbert and Szabo, Peter M and Szabó, István and Bálint, Ádám and Urbán, Péter and Herczeg, Róbert and Gyenesei, Attila and Nagy, Ágnes and Pereszlényi, Csaba István and Babinszky, Gergely Csaba and Dudás, Gábor and Terhes, Gabriella and Zöldi, Viktor and Lovas, Róbert and Tenczer, Szabolcs and Kornya, László and Jakab, Ferenc}, doi = {10.3390/v12121401}, journal-iso = {VIRUSES-BASEL}, journal = {VIRUSES}, volume = {12}, unique-id = {31733407}, year = {2020}, eissn = {1999-4915}, orcid-numbers = {Kemenesi, Gábor/0000-0001-9775-3065; Tóth, Gábor Endre/0000-0002-7201-9646; Solymosi, Norbert/0000-0003-1783-2041; Herczeg, Róbert/0000-0002-5903-0082; Terhes, Gabriella/0000-0002-7301-9672; Lovas, Róbert/0000-0001-9409-2855} } @article{MTMT:31331388, title = {Nursing homes and the elderly regarding the COVID-19 pandemic: situation report from Hungary}, url = {https://m2.mtmt.hu/api/publication/31331388}, author = {Kemenesi, Gábor and Kornya, László and Tóth, Gábor Endre and Kurucz, Kornélia and Zeghbib, Safia and Somogyi, Balázs Antal and Zoldi, Viktor and Urbán, Péter and Herczeg, Róbert and Jakab, Ferenc}, doi = {10.1007/s11357-020-00195-z}, journal-iso = {GEROSCIENCE}, journal = {GEROSCIENCE: OFFICIAL JOURNAL OF THE AMERICAN AGING ASSOCIATION (AGE)}, volume = {42}, unique-id = {31331388}, issn = {2509-2715}, abstract = {The global impact of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic is significant in terms of public health effects and its long-term socio-economic implications. Among all social groups, the elderly is by far the most affected age group regarding morbidity and mortality. In multiple countries spanning several continents, there are an increasing number of reports referencing the novel coronavirus disease-2019 (COVID-19) spread among nursing homes. These areas are now recognized as potent hotspots regarding the pandemic, which one considers with special regard. Herein, we present currently available data of fatal COVID-19 cases throughout Hungary, along with the analysis of the co-morbidity network. We also report on viral genomic data originating from a nursing home resident. The genomic data was used for viral haplotype network analysis. We emphasize the urgent need for public health authorities to focus on nursing homes and residential service units worldwide, especially in the care of the elderly and infirmed. Our results further emphasize the recent statement released by the World Health Organization (WHO) regarding the vulnerability among seniors and especially the high risk of COVID-19 emergence throughout nursing and social homes.}, keywords = {OUTBREAK; genome sequencing; Hotspot; nCoV2019}, year = {2020}, eissn = {2509-2723}, pages = {1093-1099}, orcid-numbers = {Kemenesi, Gábor/0000-0001-9775-3065; Tóth, Gábor Endre/0000-0002-7201-9646; Kurucz, Kornélia/0000-0001-6190-1265; Herczeg, Róbert/0000-0002-5903-0082} } @article{MTMT:31304588, title = {The role of apoptosis in the complex pathogenesis of the most common obstetrics and gynaecology diseases}, url = {https://m2.mtmt.hu/api/publication/31304588}, author = {Kovács, Péter and Joó, József Gábor and Tamás, Valentina and Molnár, Z. and Burik-Hajas, Dóra and Bódis, József and Kornya, László}, doi = {10.1556/2060.2020.00014}, journal-iso = {PHYSIOL INT}, journal = {PHYSIOLOGY INTERNATIONAL}, volume = {107}, unique-id = {31304588}, issn = {2498-602X}, year = {2020}, eissn = {2677-0164}, pages = {106-119}, orcid-numbers = {Joó, József Gábor/0000-0001-9820-6514} } @article{MTMT:30910717, title = {Survival and early complications of preterm infants with birthweight less than 500 grams during a 10‐year period in Hungary}, url = {https://m2.mtmt.hu/api/publication/30910717}, author = {Varga, Péter and Berecz, Botond and Magyar, Zsófia and Pete, Barbara and Romicsné Görbe, Éva and Dombi, Zsófia Anna and Sassi, Lilla and Fanczal, Eszter and Ács, Nándor and Kornya, László and Joó, József Gábor and Valek, Andrea and Harmath, Ágnes and Gasparics, Ákos}, doi = {10.1111/ppe.12598}, journal-iso = {PAEDIATR PERINAT EP}, journal = {PAEDIATRIC AND PERINATAL EPIDEMIOLOGY}, volume = {34}, unique-id = {30910717}, issn = {0269-5022}, year = {2020}, eissn = {1365-3016}, pages = {565-571}, orcid-numbers = {Magyar, Zsófia/0000-0002-9123-6718; Ács, Nándor/0000-0002-1919-1869; Joó, József Gábor/0000-0001-9820-6514; Harmath, Ágnes/0000-0001-8105-3363; Gasparics, Ákos/0000-0003-3902-685X} } @{MTMT:32507335, title = {Fénytől védett asszisztált reprodukciós laboratóriumi eljárásokhoz használatos eszközcsalád}, url = {https://m2.mtmt.hu/api/publication/32507335}, author = {Gödöny, Krisztina and Bódis, József and Kornya, László}, unique-id = {32507335}, year = {2018} } @article{MTMT:3217276, title = {A legjelentősebb angiogeneticus gének méhlepényi expressziójának változásai a méhen belüli növekedési visszamaradás hátterében}, url = {https://m2.mtmt.hu/api/publication/3217276}, author = {Kovács, Péter and Rab, Attila Zoltán and Szentpeteri, I and Joó, József Gábor and Kornya, László}, doi = {10.1556/650.2017.30622}, journal-iso = {ORV HETIL}, journal = {ORVOSI HETILAP}, volume = {158}, unique-id = {3217276}, issn = {0030-6002}, abstract = {Placental vascular endothelial growth factor A (VEGF-A) gene and endoglin gene are both overexpressed in placental samples obtained from pregnancies with intrauterine growth restriction compared to normal pregnancies. In the background of these changes a mechanism can be supposed, in which the increased endoglin activity in intrauterine growth restriction (IUGR) leads to impaired placental circulation through an antioangiogenetic effect. This results in the development of placental vascular dysfunction and chronic fetal hypoxia. It is chronic hypoxia that turns on VEGF-A as a compensatory mechanism to improve fetal vascular blood supply by promoting placental blood vessel formation. Although the maternal serum placental growth factor (PlGF) level is a potential predictor for both IUGR and praeeclampsia, placental PlGF gene activity may be less of an active in the regulation of placental circulation in IUGR pregnancies during the later stages of gestation. Orv. Hetil., 2017, 158(16), 612-617.}, year = {2017}, eissn = {1788-6120}, pages = {612-617}, orcid-numbers = {Joó, József Gábor/0000-0001-9820-6514} }