@article{MTMT:34145841, title = {Remineralization of Tooth Enamel with Hydroxyapatite Nanoparticles: an in vitro Study}, url = {https://m2.mtmt.hu/api/publication/34145841}, author = {Diana-Alexandra, FLOREA and Aurora, MOCANU and Lucian-Cristian, POP and Gheorghe, TOMOAIA and Cristina-Teodora, DOBROTA and Várhelyi, Csaba, ifj. and Maria, TOMOAIA-COTISEL}, doi = {10.24193/subbchem.2023.2.07}, journal-iso = {STUD UNIV BABES-BOLYAI CHEM}, journal = {STUDIA UNIVERSITATIS BABES-BOLYAI CHEMIA}, volume = {68}, unique-id = {34145841}, issn = {1224-7154}, abstract = {The use of toothpastes is the best way to combat enamel loss and degradation. When they also contain hydroxyapatite nanoparticles, HAP NPs, the tooth enamel can be restored by remineralization. In this study, we developed two types of toothpastes, one with nano sized HAP, noted P1, and the other with nano multi-substituted hydroxyapatite (ms-HAP, HAP-Mg-Zn-Si), noted P2, which were used to treat the artificially demineralized teeth enamel surface. The remineralization efficacy of the two toothpastes was determined on artificially created enamel lesions by suspending healthy enamel slices in demineralizing solution, made of orthophosphoric acid of 37.5% for 90 s. For this purpose, six extracted third molars were collected and twenty-four enamel slices were cut and arbitrarily allocated to the four groups, namely n = 6 enamel slices for each group. One group served as untreated (natural) enamel control, and another group comprised demineralized enamel and two test groups, firstly demineralized, and then, they were treated with toothpastes P1 and P2, respectively, each of them for ten days, and finally were noted P1 and P2 enamel surfaces. The surface morphology and roughness of all enamel specimens were studied by atomic force microscopy (AFM) before and after applying the treatment with the toothpastes. The toothpastes effect was evidenced by the average diameter of ceramic nanoparticles deposited within the superficial smooth layer on enamel surface having, at the completion of 10 days treatment, a low surface roughness close to that of natural enamel. This in vitro comparative study demonstrated that both toothpastes P1 and P2 can promote surface enamel repair by remineralization and the formation of a protective hydroxyapatite coating layer on the enamel surface treated with these toothpastes.}, year = {2023}, eissn = {2065-9520}, pages = {99-113} } @{MTMT:34145735, title = {Thermal and Spectroscopical Analysis of Platinum(II) Complexes with Glyoximes, Schiff Bases and Thiosemicarbazones}, url = {https://m2.mtmt.hu/api/publication/34145735}, author = {Várhelyi, Csaba, ifj. and GYÖRGY, POKOL and IMRE-MIKLÓS, SZILÁGYI and RALUCA-ANCA, MEREU and JÁNOS, MADARÁSZ and ROLAND, SZALAY and JUDIT, PAPP and MELINDA, SIMON-VÁRHELYI and JUDITH, MIHÁLY}, booktitle = {3rd Journal of Thermal Analysis and Calorimetry Conference and 9th V4 (Joint Czech-Hungarian-Polish-Slovakian) Thermoanalytical Conference}, unique-id = {34145735}, abstract = {After the discovery of anticancer activity of cisplatin by Barnett Rosenberg, platinum coordination complexes became a very important class of drugs. In recent years other platinum-based drugs have entered in clinical trials, and high efforts have been made to find more active and less toxic agents for cancer treatment in humans. Many pathogenic bacteria show resistance toward antibiotics, therefore it is necessary to find new compounds to control the multidrug-resistant microorganisms. Other platinum coordination and organometallic complexes have demonstrated applications in homogeneous catalysis, such as the oxidation of ethanol to acetic acid or acetaldehyde, the oxidation of sulfur dioxide to sulfuric acid and, furthermore, in catalytic combustion, hydrogenation reactions. In our research project new Pt(II) complexes were synthesized from the reaction between azomethine derivatives (glyoximes, Schiff bases and thiosemicarbazones) and PtCl2 salt, in suitable solvent. After presenting a short historical survey, classification, and possible application fields of these compounds, we report the study of their thermoanalytical behaviour (TG-DTG-DTA), spectroscopic features (such as FTIR, NMR, UV-VIS, Raman spectroscopy, mass spectrometry) as well as their powder XRD and AFM or SEM investigations. The biological activity of complexes, especially their antibacterial activity, will also be discussed.}, keywords = {azomethines}, year = {2023}, pages = {95-96} } @article{MTMT:34107401, title = {Fe spin states and redox processes in Schiff base type complexes}, url = {https://m2.mtmt.hu/api/publication/34107401}, author = {Várhelyi, Csaba, ifj. and Szőke, Á. and Sziráki, Laura and Tomoaia-Cotișel, M. and Homonnay, Zoltán and Szalay, Roland and Simon-Várhelyi, M. and Mereu, R.-A. and Pokol, György and Szilágyi, Imre Miklós and Papp, J. and Mihály, Judith and Kuzmann, Ernő}, doi = {10.1007/s10967-023-09095-w}, journal-iso = {J RADIOANAL NUCL CHEM}, journal = {JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY}, volume = {332}, unique-id = {34107401}, issn = {0236-5731}, year = {2023}, eissn = {1588-2780}, pages = {4125-4139}, orcid-numbers = {Homonnay, Zoltán/0000-0001-5299-5394; Szalay, Roland/0000-0003-3535-5365; Pokol, György/0000-0003-1597-9808; Kuzmann, Ernő/0000-0002-0183-6649} } @CONFERENCE{MTMT:33646163, title = {Szemi- és tioszemikarbazonokkal képzett platina- és nikkel-komplexek előállítása, valamint fizikai-kémiai és biológiai vizsgálatuk (Pt- and Ni-complexes Syntheses with Semi- and Thiosemicarbazones, and their Physical-Chemical and Biological Study)}, url = {https://m2.mtmt.hu/api/publication/33646163}, author = {Várhelyi, Csaba, ifj. and Pokol, György and Szalay, Roland and MEREU, RALUCA-ANCA and Simon-Várhelyi, Melinda and Tötös, Róbert and Madarász, János and PAPP, JUDIT and Mihály, Judith}, booktitle = {A Magyar Tudomány Napja Erdélyben 2022: Tudomány: út a világ megismeréséhez}, unique-id = {33646163}, year = {2022}, pages = {28-30}, orcid-numbers = {Pokol, György/0000-0003-1597-9808; Szalay, Roland/0000-0003-3535-5365} } @inproceedings{MTMT:33645223, title = {Novel Copper Complexes with Glyoximes, Amines, Schiff Bases, Semi- and Thiosemicarbazones; Synthesis and Physico-Chemical Analysis}, url = {https://m2.mtmt.hu/api/publication/33645223}, author = {Várhelyi, Csaba, ifj. and Szalay, Roland and Pokol, György and Madarász, János and Szilágyi, Imre Miklós and Huszthy, Péter and Simon-Várhelyi, Melinda and Tötös, Róbert and RALUCA-ANCA, MEREU and ALEXANDRA, AVRAM and Korecz, László and May, Nóra Veronika and Mihály, Judith}, booktitle = {Proceedings of the 28th International Symposium on Analytical and Environmental Problems}, unique-id = {33645223}, year = {2022}, pages = {46-50}, orcid-numbers = {Szalay, Roland/0000-0003-3535-5365; Pokol, György/0000-0003-1597-9808; Huszthy, Péter/0000-0001-7305-3312; May, Nóra Veronika/0000-0003-4770-4681} } @CONFERENCE{MTMT:33645214, title = {Glioximokkal, aminokkal, bórsav-észterekkel és Schiff-bázisokkal képzett új vas(II)-komplexek fizikai-kémiai elemzése, és biológiai tulajdonságainak vizsgálata (Novel Iron(II) Complexes with Glyoximes, Amines, Borate Esters and Schiff-Bases, their Physico-Chemical Analysis and Biological Properties Study)}, url = {https://m2.mtmt.hu/api/publication/33645214}, author = {Várhelyi, Csaba, ifj. and Szalay, Roland and Kuzmann, Ernő and Homonnay, Zoltán and Pokol, György and Madarász, János and PAPP, JUDIT and MEREU, RALUCA-ANCA and Huszthy, Péter and Simon-Várhelyi, Melinda and AVRAM, ALEXANDRA and Mihály, Judith}, booktitle = {XXVIII. Nemzetközi Vegyészkonferencia = 28th International Conference on Chemistry}, unique-id = {33645214}, year = {2022}, pages = {44-44}, orcid-numbers = {Szalay, Roland/0000-0003-3535-5365; Kuzmann, Ernő/0000-0002-0183-6649; Homonnay, Zoltán/0000-0001-5299-5394; Pokol, György/0000-0003-1597-9808; Huszthy, Péter/0000-0001-7305-3312} } @article{MTMT:33645156, title = {Synthesis of Pt(II)-complexes with symmetrical and unsymmetrical glyoximes, their physical-chemical and biological study}, url = {https://m2.mtmt.hu/api/publication/33645156}, author = {Várhelyi, Csaba, ifj. and Szalay, Roland and Pokol, György and Madarász, János and Marincaș , Laura and MEREU, Raluca-Anca and Mihály, Judith and PAPP, Judit and Simon-Várhelyi, Melinda and Tötös, Róbert and TOMOAIA- COTIŞEL, Maria}, doi = {10.24193/subbchem.2022.4.21}, journal-iso = {STUD UNIV BABES-BOLYAI CHEM}, journal = {STUDIA UNIVERSITATIS BABES-BOLYAI CHEMIA}, volume = {67}, unique-id = {33645156}, issn = {1224-7154}, year = {2022}, eissn = {2065-9520}, pages = {315-335}, orcid-numbers = {Szalay, Roland/0000-0003-3535-5365; Pokol, György/0000-0003-1597-9808} } @article{MTMT:33645082, title = {Réz(II)-komplexek szintézise Schiff-bázisokkal és alfa-dioximokkal valamint ezek fizikai-kémiai vizsgálata (Synthesis of copper(II)-complexes with Schiff bases and alpha-dioximes, and their physical-chemical study)}, url = {https://m2.mtmt.hu/api/publication/33645082}, author = {M., FISCHER and Várhelyi, Csaba, ifj.}, journal-iso = {MŰSZAKI SZEMLE (EMT)}, journal = {MŰSZAKI SZEMLE (EMT)}, volume = {4}, unique-id = {33645082}, issn = {1454-0746}, year = {2022}, eissn = {2458-0201}, pages = {1-7} } @article{MTMT:33645073, title = {Fe(II)-komplexek szintézise alfa-dioximokkal, alkalmazhatósági lehetőségeik, valamint fizikai-kémiai és biológiai vizsgálatuk (Synthesis of Fe(II) complexes with alpha-dioximes, their applicability and their physicochemical and biological investigation)}, url = {https://m2.mtmt.hu/api/publication/33645073}, author = {B., SZÁSZ and Várhelyi, Csaba, ifj.}, journal-iso = {MŰSZAKI SZEMLE (EMT)}, journal = {MŰSZAKI SZEMLE (EMT)}, volume = {3}, unique-id = {33645073}, issn = {1454-0746}, year = {2022}, eissn = {2458-0201}, pages = {28-34} } @article{MTMT:33645059, title = {Co(III)-komplexek előállítása α-dioximokkal és azidokkal, valamint fizikai-kémiai és biológiai tulajdonságainak vizsgálata (The synthesis of Co(III) complexes with α-dioximes and azides. The study of physical-chemical and biological properties)}, url = {https://m2.mtmt.hu/api/publication/33645059}, author = {Á., GERE and Várhelyi, Csaba, ifj.}, journal-iso = {MŰSZAKI SZEMLE (EMT)}, journal = {MŰSZAKI SZEMLE (EMT)}, volume = {3}, unique-id = {33645059}, issn = {1454-0746}, year = {2022}, eissn = {2458-0201}, pages = {17-21} }