@misc{MTMT:34577002,
	title = {Analgesic effects of cyclodextrin derivatives via modulation of Transient Receptor Potential Ankyrin 1 ion channel function},
	url = {https://m2.mtmt.hu/api/publication/34577002},
	author = {Nehr-Majoros, Andrea Kinga and Bencze, Noémi and Payrits, Maja and Kemény, Ágnes and György, Sétáló Jr. and Helyes, Zsuzsanna and Szőke, Éva},
	unique-id = {34577002},
	year = {2024},
	orcid-numbers = {Kemény, Ágnes/0000-0002-4523-3938}
}

@misc{MTMT:34576980,
	title = {Effect of estradiol on the Transient Receptor Potential Vanilloid 1 and Ankyrin 1 receptors regulated pain responses},
	url = {https://m2.mtmt.hu/api/publication/34576980},
	author = {Payrits, Maja and Csekő, Kata and Pohóczky, Krisztina and Dávid, Ernszt and Klaudia, Barabás and Nehr-Majoros, Andrea Kinga and Bencze, Noémi and Nemes, Balázs and Helyes, Zsuzsanna and Szőke, Éva},
	unique-id = {34576980},
	year = {2024},
	orcid-numbers = {Pohóczky, Krisztina/0000-0003-0385-5162}
}

@article{MTMT:32084429,
	title = {Proof-of-Concept for the Analgesic Effect and Thermoregulatory Safety of Orally Administered Multi-Target Compound SZV 1287 in Mice: A Novel Drug Candidate for Neuropathic Pain},
	url = {https://m2.mtmt.hu/api/publication/32084429},
	author = {Horváth, Ádám István and Szentes, Nikolett and Tékus, Valéria and Payrits, Maja and Szőke, Éva and Pótóné Oláh, Emőke and Garami, András and Fliszár-Nyúl, Eszter and Poór, Miklós and Pápayné Sár, Cecília and Kálai, Tamás and Pál, Szilárd and Percze, Krisztina and Nagyné Scholz, Éva and Mészáros, Tamás and Tóth, Blanka and Mátyus, Péter and Helyes, Zsuzsanna},
	doi = {10.3390/biomedicines9070749},
	journal-iso = {BIOMEDICINES},
	journal = {BIOMEDICINES},
	volume = {9},
	unique-id = {32084429},
	year = {2021},
	eissn = {2227-9059},
	orcid-numbers = {Garami, András/0000-0003-2493-0571; Fliszár-Nyúl, Eszter/0000-0003-0923-0059; Percze, Krisztina/0000-0002-4124-1893; Mészáros, Tamás/0000-0002-7396-9678; Mátyus, Péter/0000-0003-3963-9445}
}

@article{MTMT:31848850,
	title = {Analgesic Effects of Lipid Raft Disruption by Sphingomyelinase and Myriocin via Transient Receptor Potential Vanilloid 1 and Transient Receptor Potential Ankyrin 1 Ion Channel Modulation},
	url = {https://m2.mtmt.hu/api/publication/31848850},
	author = {Horváth, Ádám and Payrits, Maja and Steib, Anita and Kántás, Boglárka and Biró-Sütő, Tünde and Erostyák, János and Makkai, Géza and Sághy, Éva and Helyes, Zsuzsanna and Szőke, Éva},
	doi = {10.3389/fphar.2020.593319},
	journal-iso = {FRONT PHARMACOL},
	journal = {FRONTIERS IN PHARMACOLOGY},
	volume = {11},
	unique-id = {31848850},
	year = {2021},
	eissn = {1663-9812},
	orcid-numbers = {Sághy, Éva/0000-0002-4031-3461}
}

@article{MTMT:31823277,
	title = {Analyzing the Carotenoid Composition of Melilot (Melilotus officinalis (L.) Pall.) Extracts and the Effects of Isolated (All-E)-lutein-5,6-epoxide on Primary Sensory Neurons and Macrophages},
	url = {https://m2.mtmt.hu/api/publication/31823277},
	author = {Horváth, Györgyi and Csikós, Eszter and Andres, Eichertné Violetta and Bencsik, Tímea and Takátsy, Anikó and Gulyás, Gergely and Turcsi, Erika Margit and Deli, József and Szőke, Éva and Kemény, Ágnes and Payrits, Maja and Szente, Lajos and Kocsis, Marianna and Molnár, Péter and Helyes, Zsuzsanna},
	doi = {10.3390/molecules26020503},
	journal-iso = {MOLECULES},
	journal = {MOLECULES},
	volume = {26},
	unique-id = {31823277},
	issn = {1420-3049},
	year = {2021},
	eissn = {1420-3049},
	orcid-numbers = {Horváth, Györgyi/0000-0001-5344-0294; Csikós, Eszter/0000-0002-5368-9492; Deli, József/0000-0002-0625-6117; Szőke, Éva/0000-0003-3433-8459; Kemény, Ágnes/0000-0002-4523-3938}
}

@article{MTMT:31818502,
	title = {Hemokinin-1 as a Mediator of Arthritis-Related Pain via Direct Activation of Primary Sensory Neurons},
	url = {https://m2.mtmt.hu/api/publication/31818502},
	author = {Borbély, Éva and Hunyady, Ágnes and Pohóczky, Krisztina and Payrits, Maja and Botz, Bálint and Mócsai, Attila and Berger, Alexandra and Szőke, Éva and Helyes, Zsuzsanna},
	doi = {10.3389/fphar.2020.594479},
	journal-iso = {FRONT PHARMACOL},
	journal = {FRONTIERS IN PHARMACOLOGY},
	volume = {11},
	unique-id = {31818502},
	year = {2021},
	eissn = {1663-9812},
	orcid-numbers = {Borbély, Éva/0000-0002-1234-4391; Pohóczky, Krisztina/0000-0003-0385-5162; Mócsai, Attila/0000-0002-0512-1157; Szőke, Éva/0000-0003-3433-8459}
}

@{MTMT:31684068,
	title = {Resolvin D1 and D2 inhibit Transient Receptor Potential Vanilloid 1 and Ankyrin 1 Ion Channel activation on sensory neurons via lipid raft modification},
	url = {https://m2.mtmt.hu/api/publication/31684068},
	author = {Payrits, Maja and Ádám, Horváth and Biró-Sütő, Tünde and János, Erostyák and Géza, Makkai and Sághy, Éva and Pohóczky, Krisztina and Kecskés, Angéla and Kecskés, Miklós and Szolcsányi, János and Helyes, Zsuzsanna and Szőke, Éva},
	booktitle = {Proceedings of the EFOP-3.6.2-16-2017-00006 (LIVE LONGER) project},
	unique-id = {31684068},
	year = {2020},
	pages = {59-59},
	orcid-numbers = {Sághy, Éva/0000-0002-4031-3461; Pohóczky, Krisztina/0000-0003-0385-5162}
}

@article{MTMT:31625361,
	title = {In vitro and in vivo evidence for the role of lipid rafts in Ca2+-gating of the Transient Receptor Potential channels in sensory neurons},
	url = {https://m2.mtmt.hu/api/publication/31625361},
	author = {Szőke, Éva and Horvath, Adam and Biró-Sütő, Tünde and Sághy, Éva and Payrits, Maja and Erostyák, János and Makkai, Géza and Szolcsányi, János and Helyes, Zsuzsanna},
	doi = {10.1096/fasebj.2020.34.s1.05167},
	journal-iso = {FASEB J},
	journal = {FASEB JOURNAL},
	volume = {34},
	unique-id = {31625361},
	issn = {0892-6638},
	keywords = {Biology; Biochemistry & Molecular Biology},
	year = {2020},
	eissn = {1530-6860},
	orcid-numbers = {Sághy, Éva/0000-0002-4031-3461}
}

@article{MTMT:31608849,
	title = {Antinociceptive Effects of Lipid Raft Disruptors, a Novel Carboxamido-Steroid and Methyl β-Cyclodextrin, in Mice by Inhibiting Transient Receptor Potential Vanilloid 1 and Ankyrin 1 Channel Activation},
	url = {https://m2.mtmt.hu/api/publication/31608849},
	author = {Horváth, Ádám and Biró-Sütő, Tünde and Kántás, Boglárka and Payrits, Maja and Skodáné Földes, Rita and Szánti-Pintér, Eszter and Helyes, Zsuzsanna and Szőke, Éva},
	doi = {10.3389/fphys.2020.559109},
	journal-iso = {FRONT PHYSIOL},
	journal = {FRONTIERS IN PHYSIOLOGY},
	volume = {11},
	unique-id = {31608849},
	year = {2020},
	eissn = {1664-042X},
	orcid-numbers = {Skodáné Földes, Rita/0000-0002-9810-1509; Szánti-Pintér, Eszter/0000-0001-8263-9884}
}

@article{MTMT:31387590,
	title = {Resolvin D1 and D2 inhibit transient receptor potential vanilloid 1 and ankyrin 1 ion channel activation on sensory neurons via lipid raft modification},
	url = {https://m2.mtmt.hu/api/publication/31387590},
	author = {Payrits, Maja and Horváth, Ádám and Biró-Sütő, Tünde and Erostyák, János and Makkai, Géza and Sághy, Éva and Pohóczky, Krisztina and Kecskés, Angéla and Kecskés, Miklós and Szolcsányi, János and Helyes, Zsuzsanna and Szőke, Éva},
	doi = {10.3390/ijms21145019},
	journal-iso = {INT J MOL SCI},
	journal = {INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES},
	volume = {21},
	unique-id = {31387590},
	issn = {1661-6596},
	abstract = {Transient Receptor Potential Vanilloid 1 and Ankyrin 1 (TRPV1, TRPA1) cation channels are expressed in nociceptive primary sensory neurons and regulate nociceptor and inflammatory functions. Resolvins are endogenous lipid mediators. Resolvin D1 (RvD1) is described as a selective inhibitor of TRPA1-related postoperative and inflammatory pain in mice acting on the G protein-coupled receptor DRV1/GPR32. Resolvin D2 (RvD2) is a very potent TRPV1 and TRPA1 inhibitor in DRG neurons, and decreases inflammatory pain in mice acting on the GPR18 receptor, via TRPV1/TRPA1-independent mechanisms. We provided evidence that resolvins inhibited neuropeptide release from the stimulated sensory nerve terminals by TRPV1 and TRPA1 activators capsaicin (CAPS) and allyl-isothiocyanate (AITC), respectively. We showed that RvD1 and RvD2 in nanomolar concentrations significantly decreased TRPV1 and TRPA1 activation on sensory neurons by fluorescent calcium imaging and inhibited the CAPS-and AITC-evoked45Ca-uptake on TRPV1-and TRPA1-expressing CHO cells. Since CHO cells are unlikely to express resolvin receptors, resolvins are suggested to inhibit channel opening through surrounding lipid raft disruption. Here, we proved the ability of resolvins to alter the membrane polarity related to cholesterol composition by fluorescence spectroscopy. It is concluded that targeting lipid raft integrity can open novel peripheral analgesic opportunities by decreasing the activation of nociceptors. © 2020 by the authors. Licensee MDPI, Basel, Switzerland.},
	keywords = {LIPID RAFTS; transient receptor potential channel; sensory neuron; resolvin D1; nerve terminal; Resolvin D2},
	year = {2020},
	eissn = {1422-0067},
	orcid-numbers = {Sághy, Éva/0000-0002-4031-3461; Pohóczky, Krisztina/0000-0003-0385-5162}
}