@article{MTMT:33856409, title = {Paclitaxel Protects against Isoproterenol-Induced Damage in Rat Myocardium: Its Heme-Oxygenase Mediated Role in Cardiovascular Research}, url = {https://m2.mtmt.hu/api/publication/33856409}, author = {Matusovits, Danica and Murlasits, Zsolt and Kupai, Krisztina and Baráth, Zoltán Lajos and Hsu, Linkang and Osváth, Péter and Szűcs, Miklós and Priksz, Dániel and Juhász, Béla and Radák, Zsolt and Várkonyi, Tamás and Pávó, Imre and Pósa, Anikó}, doi = {10.3390/antiox12051129}, journal-iso = {ANTIOXIDANTS-BASEL}, journal = {ANTIOXIDANTS}, volume = {12}, unique-id = {33856409}, abstract = {(1) Background: In cardiovascular applications, paclitaxel inhibits smooth muscle cell proliferation and migration and significantly reduces the occurrence of restenosis and target lesion revascularization. However, the cellular effects of paclitaxel in the myocardium are not well understood; (2) Methods: Wistar rats were divided into four groups: control (CTRL), isoproterenol (ISO) treated (1 mg/kg) and two groups treated with paclitaxel (PAC), which was administrated (10 mg/kg/day) for 5 days by gavage/per os alone or in combination (ISO + PAC) 3 weeks after ISO treatment. Ventricular tissue was harvested 24 h later for measurements of heme oxygenase (HO-1), reduced glutathione (GSH), oxidized glutathione (GSSG), superoxide dismutase (SOD), NF-κB, TNF-α and myeloperoxidase (MPO); (3) Results: HO-1 protein concentration, HO-1 activity, SOD protein concentration and total glutathione significantly decreased in response to ISO treatment. When PAC was administered in conjunction with ISO, HO-1, SOD concentration and total glutathione were not different from control levels. MPO activity, NF-κB concentration and TNF-α protein concentration were significantly increased in the ISO-only group, while the levels of these molecules were restored when PAC was co-administered; (4) Conclusions: Oral administration of PAC can maintain the expression of important antioxidants, anti-inflammatory molecules, HO-1, SOD and GSH, and suppress the production of TNF-α, MPO and NF-κB, which are involved in myocardial damage. The principal component of this cellular defense seems to be the expression of HO-1.}, year = {2023}, eissn = {2076-3921}, orcid-numbers = {Murlasits, Zsolt/0000-0003-4101-3417; Kupai, Krisztina/0000-0002-0644-1718; Baráth, Zoltán Lajos/0000-0003-0636-6313; Hsu, Linkang/0009-0001-2220-1562; Szűcs, Miklós/0000-0002-8606-996X; Radák, Zsolt/0000-0003-1297-6804; Várkonyi, Tamás/0000-0001-6833-3563; Pósa, Anikó/0000-0003-2167-2888} } @article{MTMT:33824973, title = {The Effect of Aerobic Exercise on Variation of Oxidative Stress, hs-CRP and Cortisol Induced by Sleep Deficiency}, url = {https://m2.mtmt.hu/api/publication/33824973}, author = {Park, J.-S. and Murlasits, Zsolt and Kim, S.}, doi = {10.3390/healthcare11081201}, journal-iso = {HEALTHCARE-BASEL}, journal = {HEALTHCARE}, volume = {11}, unique-id = {33824973}, year = {2023}, eissn = {2227-9032}, orcid-numbers = {Murlasits, Zsolt/0000-0003-4101-3417} } @article{MTMT:33802696, title = {Physiological responses to an incremental swim test with different breathing frequencies in competitive male youth swimmers}, url = {https://m2.mtmt.hu/api/publication/33802696}, author = {Murlasits, Zsolt and László, Szilárd and Prókai, Judit and Sebesi, Balázs and Scherer, J. and Tóvári, Ferenc and Atlasz, Tamás and Tovari, A. and Katona, Máté and Cselkó, Alexandra and Petrovics, Péter and Balázs, Bence and Váczi, Márk}, doi = {10.7752/jpes.2023.03086}, journal-iso = {J PHYS EDUCATION SPORT}, journal = {JOURNAL OF PHYSICAL EDUCATION AND SPORT}, volume = {23}, unique-id = {33802696}, issn = {2247-8051}, year = {2023}, eissn = {2247-806X}, pages = {697-703}, orcid-numbers = {Murlasits, Zsolt/0000-0003-4101-3417; Sebesi, Balázs/0000-0002-7786-0469; Atlasz, Tamás/0000-0002-8112-8633} } @article{MTMT:33754869, title = {The Effects of a 12-Week-Long Sand Exercise Training Program on Neuromechanical and Functional Parameters in Type II Diabetic Patients with Neuropathy}, url = {https://m2.mtmt.hu/api/publication/33754869}, author = {Prókai, Judit and Murlasits, Zsolt and Bánhidi, Miklós and Csóka, László and Gréci, Viktória and Atlasz, Tamás and Váczi, Márk}, doi = {10.3390/ijerph20075413}, journal-iso = {INT J ENV RES PUB HE}, journal = {INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH}, volume = {20}, unique-id = {33754869}, issn = {1661-7827}, abstract = {Studies have proven the effectiveness of different weight-bearing exercise interventions for diabetic patients with neuropathy; however, several adverse effects were reported using solid surfaces. Thus, in the present study, we investigated the effects of a novel sand exercise training intervention on biomechanical and functional parameters in seven diabetic patients (age = 62.7 ± 9.7 years) with neuropathy. Patients underwent a 12-week sand exercise training program, using strengthening, stretching, balance, and gait exercises. They were tested for ankle plantar- and dorsiflexion peak torque, active range of motion (ROM), timed up and go (TUG), and bilateral static balance. EMG activity of tibialis anterior (TA), gastrocnemius medialis (GM), and lateralis (GL) muscles were measured during unilateral isometric contraction in plantar- and dorsiflexion. In the intervention period, plantarflexion peak torque improved significantly (p = 0.033), while dorsiflexion torque remained unchanged. Plantar- and dorsiflexion ROM increased (p = 0.032) and (p = 0.021), respectively. EMG activity of GM (p = 0.005) and GL (p = 0.002) measured during dorsiflexion and postural sway in the balance test, as well as time to complete the TUG test, decreased significantly (p = 0.021) and (p = 0.002), respectively. No adverse effect was reported during the intervention period. We concluded that sand exercise training can be a safe and effective method to improve plantarflexion strength, ankle flexibility, and balance, which is reflected in better gait function in patients with diabetic peripheral neuropathy (DPN).}, keywords = {Gait; BALANCE; EMG; Physical therapy; unstable surface; Co-activation}, year = {2023}, eissn = {1660-4601}, orcid-numbers = {Murlasits, Zsolt/0000-0003-4101-3417; Csóka, László/0009-0005-1255-198X; Atlasz, Tamás/0000-0002-8112-8633} } @article{MTMT:33567314, title = {Frontal Plane Neurokinematic Mechanisms Stabilizing the Knee and the Pelvis during Unilateral Countermovement Jump in Young Trained Males}, url = {https://m2.mtmt.hu/api/publication/33567314}, author = {Vadász, Kitty and Varga, Mátyás and Sebesi, Balázs and Hortobágyi, Tibor and Murlasits, Zsolt and Atlasz, Tamás and Fésüs, Ádám and Váczi, Márk}, doi = {10.3390/ijerph20010220}, journal-iso = {INT J ENV RES PUB HE}, journal = {INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH}, volume = {20}, unique-id = {33567314}, issn = {1661-7827}, abstract = {(1) The unilateral countermovement jump is commonly used to examine frontal plane kinetics during unilateral loading and to identify athletes with an increased risk of lower limb injuries. In the present study, we examined the biomechanical mechanisms of knee and pelvis stabilization during unilateral vertical jumps. (2) Healthy males performed jumps on a force plate with the dominant leg. Activity of the dominant-side gluteus medius and the contralateral-side quadratus lumborum and erector spinae muscles was recorded with surface EMG. The EMG data were normalized to the EMG activity recorded during maximal voluntary isometric hip abduction and lateral trunk flexion contractions. During jumps, the propulsive impulse was measured, and the pelvis and thigh segmental orientation angles in the frontal plane were recorded and synchronized with the EMG data. (3) The magnitude of knee valgus during the jump did not correlate with hip abduction force, but negatively correlated with gluteus medius activity. This correlation became stronger when gluteus medius activity was normalized to hip abduction force. Propulsive impulse did not correlate with any neuromechanical measurement. (4) We conclude that hip abduction force itself does not regulate the magnitude of knee valgus during unilateral jumps; rather, the gluteus medius should be highly activated to increase frontal-plane knee joint stability.}, year = {2023}, eissn = {1660-4601}, orcid-numbers = {Sebesi, Balázs/0000-0002-7786-0469; Hortobágyi, Tibor/0000-0001-5732-7942; Murlasits, Zsolt/0000-0003-4101-3417; Atlasz, Tamás/0000-0002-8112-8633} } @article{MTMT:33316600, title = {Role of physical activity and cardiorespiratory fitness in metabolically healthy obesity: a narrative review}, url = {https://m2.mtmt.hu/api/publication/33316600}, author = {Murlasits, Zsolt and Kupai, Krisztina and Kneffel, Zsuzsanna}, doi = {10.1136/bmjsem-2022-001458}, journal-iso = {BMJ OPEN SPORT EXCERC MED}, journal = {BMJ OPEN SPORT & EXCERCISE MEDICINE}, volume = {8}, unique-id = {33316600}, abstract = {Obesity has been associated with a multitude of metabolic disorders, often clustering with risk factors of cardiovascular disease and type 2 diabetes mellitus, hypertension, dyslipidaemia. Overall, obesity is a worldwide, growing health concern. However, a subgroup of obese individuals with a low burden of metabolic abnormalities have been identified and described as metabolically healthy obese (MHO). Whether the MHO phenotype is protective against obesity-related metabolic disorders in the long-term is presently unclear, and current research examining the potential transition has yielded inconsistent results. In this current narrative review, we aim to provide insights on the role of physical activity (PA) and cardiorespiratory fitness (CRF) in MHO. Lifestyle factors such as PA and CRF may influence the MHO phenotype. Limited studies have characterised energy expenditure and CRF in MHO and metabolically unhealthy obese. However, higher levels of PA, less sedentary behaviour and higher CRF have been observed in MHO individuals. Considering the multiple benefits of PA, it is high time to advocate this lifestyle change beyond its influence on energy balance in a weight loss programme to improve cardiovascular and metabolic risk factors irrespective of body weight and fat mass changes. Improved CRF via increased PA, especially exercise participation, while avoiding weight gain is not only a realistic goal, but should be the primary intervention for MHO populations to prevent the transition to an abnormal metabolic state.}, year = {2022}, eissn = {2055-7647}, orcid-numbers = {Murlasits, Zsolt/0000-0003-4101-3417; Kupai, Krisztina/0000-0002-0644-1718} } @article{MTMT:32887418, title = {Sztatin-használat és inaktív életmód: csökkenti-e a sztatinok használata a fizikai aktivitási szintet kardiovaszkuláris rizikóval rendelkezőkben?}, url = {https://m2.mtmt.hu/api/publication/32887418}, author = {Kneffel, Zsuzsanna and Murlasits, Zsolt}, journal-iso = {M SPORTTUD SZLE}, journal = {MAGYAR SPORTTUDOMÁNYI SZEMLE}, volume = {23}, unique-id = {32887418}, issn = {1586-5428}, year = {2022}, pages = {57-57}, orcid-numbers = {Murlasits, Zsolt/0000-0003-4101-3417} } @{MTMT:32831817, title = {Ismert és váratlan ellenállás alkalmazásának krónikus hatása a quadriceps femoris izom propriocepciójára és erőkifejtésének szabályozására = The chronic effects of predetermined and random application of resistance on quadriceps femoris proprioception and force control}, url = {https://m2.mtmt.hu/api/publication/32831817}, author = {Gáspár, Balázs and Fésüs, Ádám and Ivusza, Patrik and Varga, Mátyás and Tar, Sarolta and Sebesi, Balázs and Murlasits, Zsolt and Váczi, Márk}, booktitle = {XX. Szentágothai János Mutidiszciplináris Konferencia és Hallgatói Verseny Absztrakt kötet = XX. János Szentágothai Multidisciplinary Conference and Student Competition}, unique-id = {32831817}, year = {2022}, pages = {281-282}, orcid-numbers = {Sebesi, Balázs/0000-0002-7786-0469; Murlasits, Zsolt/0000-0003-4101-3417} } @CONFERENCE{MTMT:32234804, title = {The Effects of Resistance Training Frequency on Muscular Strength and Hypertrophy in Elderly}, url = {https://m2.mtmt.hu/api/publication/32234804}, author = {Kneffel, Zsuzsanna and Murlasits, Zsolt and Reedc, Jacob and Kriegerd, James}, booktitle = {IV. Sport és Innováció Nemzetközi Konferencia, SPORTINNO 2021: Programfüzet absztraktokkal}, unique-id = {32234804}, year = {2021}, pages = {80-81}, orcid-numbers = {Murlasits, Zsolt/0000-0003-4101-3417} } @article{MTMT:32128211, title = {Effects of aging on proteasomal-ubiquitin system, oxidative stress balance and calcium homeostasis in middle-aged female rat colon}, url = {https://m2.mtmt.hu/api/publication/32128211}, author = {Almási, Nikoletta and Murlasits, Zsolt and Al-Awar, Amin and Csonka, Ákos and Dvorácskó, Szabolcs and Tömböly, Csaba and Török, Szilvia and Bester, D. and Pósa, Anikó and Varga, Csaba and Kupai, Krisztina}, doi = {10.1556/2060.2021.00012}, journal-iso = {PHYSIOL INT}, journal = {PHYSIOLOGY INTERNATIONAL}, volume = {108}, unique-id = {32128211}, issn = {2498-602X}, year = {2021}, eissn = {2677-0164}, pages = {27-42}, orcid-numbers = {Almási, Nikoletta/0000-0002-7371-5272; Murlasits, Zsolt/0000-0003-4101-3417; Pósa, Anikó/0000-0003-2167-2888; Varga, Csaba/0000-0002-2678-665X; Kupai, Krisztina/0000-0002-0644-1718} }