@article{MTMT:34451774,
	title = {A Belügyminisztérium egészségügyi szakmai irányelve a pyothorax (gennymell) ellátásáról},
	url = {https://m2.mtmt.hu/api/publication/34451774},
	author = {Rényi-Vámos, Ferenc István and Tóth, Imre and Takács, István},
	journal-iso = {EGÉSZSÉGÜGYI KÖZLÖNY},
	journal = {EGÉSZSÉGÜGYI KÖZLÖNY},
	volume = {73},
	unique-id = {34451774},
	issn = {2063-1146},
	year = {2023},
	pages = {1992-2003},
	orcid-numbers = {Rényi-Vámos, Ferenc István/0000-0002-0555-2096}
}

@article{MTMT:33561437,
	title = {A debreceni mellkassebészet: múlt és jelen},
	url = {https://m2.mtmt.hu/api/publication/33561437},
	author = {Takács, István and Enyedi, Attila and Váradi, Csongor and Kóder, Gergely and Mudriczki, Gábor and Tóth, Dezső},
	doi = {10.1556/1046.2021.10014},
	journal-iso = {MAGYAR SEBÉSZET},
	journal = {MAGYAR SEBÉSZET},
	volume = {75},
	unique-id = {33561437},
	issn = {0025-0295},
	year = {2022},
	eissn = {1789-4301},
	pages = {67-74},
	orcid-numbers = {Váradi, Csongor/0000-0001-7332-1524}
}

@article{MTMT:33367813,
	title = {Pigmentált orsósejtes carcinoid : esetismertetés},
	url = {https://m2.mtmt.hu/api/publication/33367813},
	author = {Tóth, László József and Varga, Imre and Valkó, Boglárka and Takács, István and Váradi, Csongor and Kóder, Gergely and Garai, Ildikó and Endes, Gábor and Méhes, Gábor},
	journal-iso = {MED THORAC (BP)},
	journal = {MEDICINA THORACALIS (BUDAPEST)},
	volume = {75},
	unique-id = {33367813},
	issn = {0238-2571},
	year = {2022},
	pages = {219},
	orcid-numbers = {Váradi, Csongor/0000-0001-7332-1524}
}

@article{MTMT:33367760,
	title = {Sclerotizáló pneumocyta előfordulása anyagunkban - 4 eset klinikopatológiai bemutatása},
	url = {https://m2.mtmt.hu/api/publication/33367760},
	author = {Tóth, László József and Enyedi, Attila and Takács, István and Mudriczki, Gábor and Brugós, László and Vaskó, Attila and Endes, Gábor and Mokánszky, Attila and Méhes, Gábor},
	journal-iso = {MED THORAC (BP)},
	journal = {MEDICINA THORACALIS (BUDAPEST)},
	volume = {75},
	unique-id = {33367760},
	issn = {0238-2571},
	year = {2022},
	pages = {218-219}
}

@article{MTMT:33334286,
	title = {Óriássejtes csonttumor tüdőáttétei : esetismertetés},
	url = {https://m2.mtmt.hu/api/publication/33334286},
	author = {Tóth, László József and Takács, István and Váradi, Csongor and Kóder, Gergely and Kardos, Tamás and Endes, Gábor and Orlik, Brigitta and Baráth, Lukács and Méhes, Gábor},
	journal-iso = {MED THORAC (BP)},
	journal = {MEDICINA THORACALIS (BUDAPEST)},
	volume = {75},
	unique-id = {33334286},
	issn = {0238-2571},
	year = {2022},
	pages = {218},
	orcid-numbers = {Váradi, Csongor/0000-0001-7332-1524}
}

@article{MTMT:33334280,
	title = {Korai stadiumú tüdő NSCLC betegek modern ellátása. A DE KK 5 éves korai eredményei klasszikus műtét és SBRT összevetésében},
	url = {https://m2.mtmt.hu/api/publication/33334280},
	author = {Kovács, Árpád and Csiki, Emese and Lieber, Attila and Takács, István and Bittner, Nóra and Trási, Krisztina and Papp, Judit and Simon, Mihály},
	journal-iso = {MED THORAC (BP)},
	journal = {MEDICINA THORACALIS (BUDAPEST)},
	volume = {75},
	unique-id = {33334280},
	issn = {0238-2571},
	year = {2022},
	pages = {167-168}
}

@article{MTMT:33334276,
	title = {Nem kissejtes tüdőrákos betegek durvalumab kezeléssel kiegészített kemoradioterápiájával szerzett kezdeti tapasztalatok},
	url = {https://m2.mtmt.hu/api/publication/33334276},
	author = {Szántó, Erika and Bittner, Nóra and Dér, Ádám and Csiki, Emese and Besenyői, Mária and Barta, Zsuzsanna and Simon, Mihály and Fodor, Andrea and Orosz, Zsuzsanna Zita and Takács, István and Kovács, Árpád},
	journal-iso = {MED THORAC (BP)},
	journal = {MEDICINA THORACALIS (BUDAPEST)},
	volume = {75},
	unique-id = {33334276},
	issn = {0238-2571},
	year = {2022},
	pages = {166-167}
}

@article{MTMT:33334273,
	title = {Nintedanib kezelés 4 év távlatában},
	url = {https://m2.mtmt.hu/api/publication/33334273},
	author = {Makai, Attila and Kovács, Tamás and Lieber, Attila and Kardos, Tamás and Orosz, Zsuzsanna Zita and Vaskó, Attila and Bittner, Nóra and Takács, István},
	journal-iso = {MED THORAC (BP)},
	journal = {MEDICINA THORACALIS (BUDAPEST)},
	volume = {75},
	unique-id = {33334273},
	issn = {0238-2571},
	year = {2022},
	pages = {159}
}

@article{MTMT:32301518,
	title = {Changes in the SARS-CoV-2 cellular receptor ACE2 levels in cardiovascular patients: a potential biomarker for the stratification of COVID-19 patients},
	url = {https://m2.mtmt.hu/api/publication/32301518},
	author = {Fagyas, Miklós and Bánhegyi, Viktor and Úri, Katalin and Enyedi, Attila and Lizanecz, Erzsébet and Mányiné Siket, Ivetta and Mártha, L and Fülöp, Gábor Áron and Radovits, Tamás and Pólos, Miklós and Merkely, Béla Péter and Kovács, Árpád and Szilvássy, Zoltán and Ungvári, Zoltán István and Édes, István and Csanádi, Zoltán and Boczán, Judit and Takács, István and Szabó, G and Balla, József and Balla, György and Seferovic, P and Papp, Zoltán and Tóth, Attila},
	doi = {10.1007/s11357-021-00467-2},
	journal-iso = {GEROSCIENCE},
	journal = {GEROSCIENCE: OFFICIAL JOURNAL OF THE AMERICAN AGING ASSOCIATION (AGE)},
	volume = {43},
	unique-id = {32301518},
	issn = {2509-2715},
	abstract = {Angiotensin-converting enzyme 2 (ACE2) is essential for SARS-CoV-2 cellular entry. Here we studied the effects of common comorbidities in severe COVID-19 on ACE2 expression. ACE2 levels (by enzyme activity and ELISA measurements) were determined in human serum, heart and lung samples from patients with hypertension (n = 540), heart transplantation (289) and thoracic surgery (n = 49). Healthy individuals (n = 46) represented the controls. Serum ACE2 activity was increased in hypertensive subjects (132%) and substantially elevated in end-stage heart failure patients (689%) and showed a strong negative correlation with the left ventricular ejection fraction. Serum ACE2 activity was higher in male (147%), overweight (122%), obese (126%) and elderly (115%) hypertensive patients. Primary lung cancer resulted in higher circulating ACE2 activity, without affecting ACE2 levels in the surrounding lung tissue. Male sex resulted in elevated serum ACE2 activities in patients with heart transplantation or thoracic surgery (146% and 150%, respectively). Left ventricular (tissular) ACE2 activity was unaffected by sex and was lower in overweight (67%), obese (62%) and older (73%) patients with end-stage heart failure. There was no correlation between serum and tissular (left ventricular or lung) ACE2 activities. Neither serum nor tissue (left ventricle or lung) ACE2 levels were affected by RAS inhibitory medications. Abandoning of ACEi treatment (non-compliance) resulted in elevated blood pressure without effects on circulating ACE2 activities. ACE2 levels associate with the severity of cardiovascular diseases, suggestive for a role of ACE2 in the pathomechanisms of cardiovascular diseases and providing a potential explanation for the higher mortality of COVID-19 among cardiovascular patients. Abandoning RAS inhibitory medication worsens the cardiovascular status without affecting circulating or tissue ACE2 levels.},
	keywords = {heart failure; RAAS inhibitors; renin-angiotensin-aldosterone system (RAAS); SARS-CoV-2; angiotensin converting enzyme-2 (ACE2); cardiovascular disease; hypertension},
	year = {2021},
	eissn = {2509-2723},
	pages = {2289-2304},
	orcid-numbers = {Merkely, Béla Péter/0000-0001-6514-0723; Ungvári, Zoltán István/0000-0002-6035-6039}
}

@article{MTMT:32113758,
	title = {Human Tissue Angiotensin Converting Enzyme (ACE) Activity Is Regulated by Genetic Polymorphisms, Posttranslational Modifications, Endogenous Inhibitors and Secretion in the Serum, Lungs and Heart},
	url = {https://m2.mtmt.hu/api/publication/32113758},
	author = {Bánhegyi, Viktor and Enyedi, Attila and Fülöp, Gábor Áron and Oláh, Attila and Mányiné Siket, Ivetta and Váradi, Csongor and Bottyán, Klaudia and Lódi, Mária and Csongrádi, Alexandra and Umar, Azeem J. and Fagyas, Miklós and Czuriga, Dániel and Édes, István and Pólos, Miklós and Merkely, Béla Péter and Csanádi, Zoltán and Papp, Zoltán and Szabó, Gábor and Radovits, Tamás and Takács, István and Tóth, Attila},
	doi = {10.3390/cells10071708},
	journal-iso = {CELLS-BASEL},
	journal = {CELLS},
	volume = {10},
	unique-id = {32113758},
	abstract = {Objective: Inhibitors of the angiotensin converting enzyme (ACE) are the primarily chosen drugs to treat heart failure and hypertension. Moreover, an imbalance in tissue ACE/ACE2 activity is implicated in COVID-19. In the present study, we tested the relationships between circulating and tissue (lung and heart) ACE levels in men. Methods: Serum, lung (n = 91) and heart (n = 72) tissue samples were collected from Caucasian patients undergoing lung surgery or heart transplantation. ACE I/D genotype, ACE concentration and ACE activity were determined from serum and tissue samples. Clinical parameters were also recorded. Results: A protocol for ACE extraction was developed for tissue ACE measurements. Extraction of tissue-localized ACE was optimal in a 0.3% Triton-X-100 containing buffer, resulting in 260 ± 12% higher ACE activity over detergent-free conditions. SDS or higher Triton-X-100 concentrations inhibited the ACE activity. Serum ACE concentration correlated with ACE I/D genotype (II: 166 ± 143 ng/mL, n = 19, ID: 198 ± 113 ng/mL, n = 44 and DD: 258 ± 109 ng/mL, n = 28, p < 0.05) as expected. In contrast, ACE expression levels in the lung tissue were approximately the same irrespective of the ACE I/D genotype (II: 1423 ± 1276 ng/mg, ID: 1040 ± 712 ng/mg and DD: 930 ± 1273 ng/mg, p > 0.05) in the same patients (values are in median ± IQR). Moreover, no correlations were found between circulating and lung tissue ACE concentrations and activities (Spearman’s p > 0.05). In contrast, a significant correlation was identified between ACE activities in serum and heart tissues (Spearman’s Rho = 0.32, p < 0.01). Finally, ACE activities in lung and the serum were endogenously inhibited to similar degrees (i.e., to 69 ± 1% and 53 ± 2%, respectively). Conclusion: Our data suggest that circulating ACE activity correlates with left ventricular ACE, but not with lung ACE in human. More specifically, ACE activity is tightly coordinated by genotype-dependent expression, endogenous inhibition and secretion mechanisms.},
	year = {2021},
	eissn = {2073-4409},
	orcid-numbers = {Váradi, Csongor/0000-0001-7332-1524; Czuriga, Dániel/0000-0002-6972-0781; Merkely, Béla Péter/0000-0001-6514-0723}
}