@article{MTMT:33577682,
	title = {Predictors and long-term outcome of intracranial hemorrhage after thrombolytic therapy for acute ischemic stroke : A prospective single center study},
	url = {https://m2.mtmt.hu/api/publication/33577682},
	author = {Fekete, Klára and Héja, Máté and Márton, Sándor József and Tóth, Judit and Horváth, László and Harman, Aletta Andrea and Fekete, István},
	doi = {10.3389/fneur.2023.1080046},
	journal-iso = {FRONT NEUR},
	journal = {FRONTIERS IN NEUROLOGY},
	volume = {14},
	unique-id = {33577682},
	issn = {1664-2295},
	abstract = {Introduction: Acute ischemic stroke (AIS) is a potentially devastating disease with high disability and mortality. Recombinant tissue plasminogen activator (rt-PA) is an effective treatment with a 2–8% possible risk for symptomatic intracranial hemorrhage (sICH). Our aim was to investigate the risk factors and long-term clinical outcomes of ICH in patients after rt-PA treatment. Methods: Consecutive patients with AIS, thrombolysed at the Department of Neurology, University of Debrecen, between 1 January 2004 and 31 August 2016 were enrolled prospectively. Risk factors, stroke severity based on the National Institute of Health Stroke Scale (NIHSS), functional outcome using the modified Rankin scale, and mortality at 1 year were compared in patients with and without ICH following rt-PA treatment. We evaluated clinical characteristics and prognosis by hemorrhage type based on the Heidelberg Bleeding Classification. Descriptive statistics, the chi-square test, the Mann–Whitney U-test, ANOVA, the Kruskal–Wallis test, a survival analysis, and logistic regression were performed as appropriate. Results: Out of 1,252 patients with thrombolysis, ICH developed in 138 patients, with 37 (2.95%) being symptomatic. Mean ages in the ICH and non-ICH groups differed significantly (p = 0.041). On admission, the 24-h NIHSS after thrombolysis was higher in patients with ICH (p < 0.0001). Large vessel occlusion was more prevalent in patients with ICH (p = 0.0095). The ICH risk was lower after intravenous thrombolysis than intra-arterial or combined thrombolysis (p < 0.0001). Both at 3 months and 1 year, the outcome was worse in patients with ICH compared to patients without ICH group (p < 0.0001). Mortality and poor outcome were more prevalent in all hemorrhage types with a tendency for massive bleeding associated with unfavorable prognosis. At 3 months with the logistic regression model, the worse outcome was detected in patients with ICH after thrombolysis, at 1 year in patients with ICH after thrombolysis and smoking. Discussion: Older age, higher NIHSS, large vessel occlusion, and intra-arterial thrombolysis may correlate with ICH. The unfavorable outcome is more common in patients with ICH. Precise scoring of post-thrombolysis bleeding might be a useful tool in the evaluation of the patient's prognosis. Our findings may help to identify predictors and estimate the prognosis of ICH in patients with AIS treated with rt-PA. Copyright © 2023},
	year = {2023},
	eissn = {1664-2295},
	orcid-numbers = {Horváth, László/0000-0003-1466-7052}
}

@{MTMT:33340608,
	title = {A gyermekkori fogszuvasodás prevenciója az Európai Unióban - a finanszírozás tagállami sajátosságai},
	url = {https://m2.mtmt.hu/api/publication/33340608},
	author = {Bencze, Zsuzsa and Kovalecz, Gabriella and Márton, Sándor József and Gáll, Tibor and Nour, Mahrouseha and Varga, Orsolya},
	booktitle = {XXII. Debreceni Fogászati Napok},
	unique-id = {33340608},
	year = {2022},
	pages = {37}
}

@article{MTMT:32593397,
	title = {Use of Complementary and Alternative Medicine Among Patients With Epilepsy and Diabetes Mellitus, Focusing on the Outcome of Treatment},
	url = {https://m2.mtmt.hu/api/publication/32593397},
	author = {Girgis, Michael Magdy Fahmy and Fekete, Klára and Homoródi, Nóra and Márton, Sándor József and Fekete, István and Horváth, László},
	doi = {10.3389/fnins.2021.787512},
	journal-iso = {FRONT NEUROSCI-SWITZ},
	journal = {FRONTIERS IN NEUROSCIENCE},
	volume = {15},
	unique-id = {32593397},
	issn = {1662-4548},
	abstract = {Introduction: Millions all over the world live with epilepsy, and they may require long-term drug treatment. The use and interest in complementary and alternative medicine (CAM) have grown over the previous years. Coadministration of herbal products with medicines may result in adverse drug reactions (ADRs) and/or unfavorable interactions. The aims of this study were to determine the prevalence of CAM use among patients with epilepsy, to compare the results to those of the patients with diabetes mellitus (DM), to reveal factors that may drive the use of CAM, and to measure outcomes and adherence. It was also our intent to have state-of-the-art information on CAM use in our region among patients with the two diseases above.Materials and Methods: We conducted a non-interventional study using a self-developed questionnaire. It was distributed among adult patients with either epilepsy or DM who also suffered from cardiovascular consequences. A database was compiled from the anonymous questionnaires filled in voluntarily by the patients. Basic statistics were used to analyze this database.Results: A total of 227 questionnaires were filled in by 127 patients (55.9%) with epilepsy and 100 patients (44.1%) with DM. Mean age was 54.54 +/- 17.33 years. Of the patients, 50.2% were male. Average body weight was 80.3 +/- 17.3 kg. Of the patients, 22 (9.7%) used CAM because they believed in CAM. Two of them reported ADRs. Among the patients with epilepsy, the ratio was only 7.9% compared to 12% among those with DM. While the number of CAM users was higher among younger patients with epilepsy, it was the elderly patients with DM who tended to use CAM.Conclusion: Attention should be paid to reliance on CAM during the follow-up. Our finding that health-conscious patients tend to use CAM more often (than the general population) may indicate it is necessary to discuss CAM usage sincerely. CAMs modulating cytochrome P450 (CYP) enzymes were the most common, leading to interactions with medication used and resulting in ADRs. This shows the importance of educating patients and treating team including clinical pharmacists in this field.},
	keywords = {EPILEPSY; diabetes mellitus; outcome; Adherence; CAM},
	year = {2022},
	eissn = {1662-453X},
	orcid-numbers = {Horváth, László/0000-0003-1466-7052}
}

@article{MTMT:32246000,
	title = {Neurophysiological examinations as adjunctive tool to imaging techniques in spontaneous intracerebral hemorrhage: IRONHEART study},
	url = {https://m2.mtmt.hu/api/publication/32246000},
	author = {Fekete, Klára and Tóth, Judit and Horváth, László and Márton, Sándor József and Héja, Máté and Csiba, László and Árokszállási, Tamás and Bagoly, Zsuzsa and Sulina, Dóra and Fekete, István},
	doi = {10.3389/fneur.2021.757078},
	journal-iso = {FRONT NEUR},
	journal = {FRONTIERS IN NEUROLOGY},
	volume = {12},
	unique-id = {32246000},
	issn = {1664-2295},
	year = {2021},
	eissn = {1664-2295},
	orcid-numbers = {Horváth, László/0000-0003-1466-7052; Bagoly, Zsuzsa/0000-0001-5314-5607}
}

@article{MTMT:32196282,
	title = {Experiences With Intravenous Thrombolysis in Acute Ischemic Stroke by Elderly Patients–A “Real World Scenario”},
	url = {https://m2.mtmt.hu/api/publication/32196282},
	author = {Héja, Máté and Fekete, István and Horváth, László and Márton, Sándor József and Fekete, Klára},
	doi = {10.3389/fneur.2021.721337},
	journal-iso = {FRONT NEUR},
	journal = {FRONTIERS IN NEUROLOGY},
	volume = {12},
	unique-id = {32196282},
	issn = {1664-2295},
	abstract = {Objectives: This retrospective single-center study aimed to investigate the risk factors, outcomes and complication rates in patients older vs. younger than 80 years treated with intravenous alteplase.
		
		Methods: Data of 1,253 thrombolysed patients were analyzed between January 1, 2004 and August 31, 2016. Vascular risk factors, stroke severity based on the NIHSS score, functional outcome using modified Rankin Scale (mRS), mortality and symptomatic intracerebral hemorrhage (SICH) were compared between two subgroups (<80 and >= 80 years).
		
		Results: 1,125 patients were included, 199 (17.6%) among them were aged over 80 years, majority (63.3%) were female (p < 0.00001). Mean age was 68.2 +/- 12.4 years, i.e., 64.7 +/- 10.8 years and 84.3 +/- 3.4 years in the younger and the older groups, respectively (p < 0.001). Atrial fibrillation and pre-stroke anticoagulation among patients over 80 years was more likely (p < 0.0005 and p = 0.02, respectively). NIHSS scores on admission and at 24 h were higher in elderly patients (p < 0.0001). ASPECT score at 24 h was less favorable in elderly patients (p = 0.007) and was associated with worse outcome. At 3 months, 59.8% of the patients from the older group had an unfavorable outcome (p < 0.0001), however 34.7% had independent outcome. The one-year- survival was significantly worse in the older group (p < 0.0001). The incidence of SICH was lower among older patients. In a logistic regression model, atrial fibrillation, heart failure, diabetes mellitus and smoking were proven as a significant independent risk factors for worse outcome.
		
		Conclusion: Although, the outcomes were less favorable in patients over 80 years of age, our results support the feasibility of using intravenous thrombolysis among patients over 80 years of age.},
	keywords = {thrombolysis; ischemic stroke; outcome; elderly; Symptomatic intracerebral hemorrhage},
	year = {2021},
	eissn = {1664-2295},
	orcid-numbers = {Horváth, László/0000-0003-1466-7052}
}

@article{MTMT:31890938,
	title = {Childhood caries management in the European Union: a cross-sectional study},
	url = {https://m2.mtmt.hu/api/publication/31890938},
	author = {Bencze, Zsuzsa and Kovalecz, Gabriella and Márton, Sándor József and Gáll, Tibor and Mahrouseh, Nour and Varga, Orsolya},
	doi = {10.1016/j.heliyon.2021.e06198},
	journal-iso = {HELIYON},
	journal = {HELIYON},
	volume = {7},
	unique-id = {31890938},
	year = {2021},
	eissn = {2405-8440}
}

@CONFERENCE{MTMT:31795067,
	title = {Társadalmi tudatosság és identitásreprezentációk a 15-25 év közötti fiatalok körében},
	url = {https://m2.mtmt.hu/api/publication/31795067},
	author = {Csoba, Judit and Márton, Sándor József and Murányi, István},
	booktitle = {Meghatározottságaink},
	unique-id = {31795067},
	year = {2020},
	pages = {15-16}
}

@article{MTMT:31176835,
	title = {The choice of antiepileptic drug treatment after status epilepticus},
	url = {https://m2.mtmt.hu/api/publication/31176835},
	author = {Horváth, László and Fekete, István and Márton, Sándor József and Fekete, Klára},
	doi = {10.1136/ejhpharm-2019-eahpconf.320},
	journal-iso = {EUR J HOSP PHARM SCI PRACT},
	journal = {EUROPEAN JOURNAL OF HOSPITAL PHARMACY-SCIENCE AND PRACTICE},
	volume = {26},
	unique-id = {31176835},
	issn = {2047-9956},
	keywords = {STATUS EPILEPTICUS},
	year = {2019},
	eissn = {2047-9964},
	pages = {A149},
	orcid-numbers = {Horváth, László/0000-0003-1466-7052}
}

@article{MTMT:30992532,
	title = {The Outcome of Status Epilepticus and Long-Term Follow-Up},
	url = {https://m2.mtmt.hu/api/publication/30992532},
	author = {Horváth, László and Fekete, István and Molnar, Mark and Válóczy, Réka and Márton, Sándor József and Fekete, Klára},
	doi = {10.3389/fneur.2019.00427},
	journal-iso = {FRONT NEUR},
	journal = {FRONTIERS IN NEUROLOGY},
	volume = {10},
	unique-id = {30992532},
	issn = {1664-2295},
	abstract = {Objective: This study was to investigate the outcome of status epilepticus (SE) associated with antiepileptic therapy during SE and in follow-up period, risk factors including age, co-morbidities, pre-existing epilepsy, and etiology in the East-Hungarian region.Methods: A prospective cross-sectional database was compiled from outpatient files between 2013 and 2017. Follow-up ended on 30.06.2018.Results: One hundred and thirty five episodes (male: 68, 50.4%) were evaluated, mean age and follow-up time being 64.1 +/- 13.9 years and 39.9 +/- 14.2 months, respectively. Of the 89 patients with pre-existing epilepsy, 34 failed to visit the outpatient unit regularly. Case fatality rate was 25.2% and 31 patients (30.7%) died after discharge due to co-morbidities; their mean survival time was 10.44 +/- 8 months. Focal, generalized and combined type epilepsies were diagnosed in 67 patients (49.6%), 47 patients (34.8%), and 21 patients (15.6%) of SE, respectively. Nine patients had non-convulsive SE (NCSE). Mean seizure-free period was 6.8 +/- 6.9 months. Patients taking carbamazepine (20.9%; OR: 0.37, 95% CI: 0.16-0.82; p = 0.018), levetiracetam (27.5%; OR: 0.51, 95% CI: 0.27-0.97; p = 0.041), or valproate (11.1%; OR: 0.18, 95% CI: 0.05-0.61; p = 0.0043) were expected to achieve seizure freedom after SE. The worst outcome was linked to advanced age, etiology, new onset status epilepticus, NCSE, and focal status epilepsy.Conclusion: This study highlights the importance of regular care and patient follow-up.},
	keywords = {FOLLOW-UP; Risk Factors; outcome; STATUS EPILEPTICUS; antiepileptic drug treatment},
	year = {2019},
	eissn = {1664-2295},
	orcid-numbers = {Horváth, László/0000-0003-1466-7052}
}

@article{MTMT:30706525,
	title = {A tanuló közösségek vizsgálata - módszertani háttér},
	url = {https://m2.mtmt.hu/api/publication/30706525},
	author = {Márkus, Edina and Teperics, Károly and Márton, Sándor József},
	doi = {10.35402/kek.2019.1.3},
	journal-iso = {KULTÚRA ÉS KÖZÖSSÉG},
	journal = {KULTÚRA ÉS KÖZÖSSÉG},
	volume = {10},
	unique-id = {30706525},
	issn = {0133-2597},
	abstract = {Tanulmányunkban arra vállalkozunk, hogy a Közösségi tanulás és társadalmi innováció kutatásunk módszertani hátterét bemutassuk. A kutatás keretében azt vizsgáljuk, hogy milyen szerepe van a tanulásnak, a felnőttek tanulásának, a közösségi tanulásnak a hátrányok leküzdésében. A közösség a hátrányos helyzetből milyen utakon, módokon keresheti a kitörést? A tanulás hogyan járul hozzá egy településrész, település, térség fejlesztéséhez, felzárkóztatásához; kisebb-nagyobb közösség átalakulásához, hogyan jelenik meg benne az egymástól tanulás, tudásátadás (tanuló közösségek)? Hogyan jelenik meg valamilyen közösségi alapú, együttműködésen alapuló újdonság, társadalmi újítás? Társadalmi újítás alatt Bradford (2004), Ferguson (2017), Kozma (2018) megközelítéséhez hasonlóan olyan új társadalmi tevékenységet értünk, amely egy probléma megoldását célozza, miközben új társadalmi magatartásokat, attitűdöket alakít ki. A tanulmányban a vizsgálat módszereit, vizsgálati szempontjait mutatjuk be.},
	year = {2019},
	eissn = {2732-0286},
	pages = {21-26},
	orcid-numbers = {Márkus, Edina/0000-0001-8495-7579}
}