@article{MTMT:34817183, title = {Milyen kezelési lehetőségeink vannak a magas lipoprotein(a) csökkentésére?}, url = {https://m2.mtmt.hu/api/publication/34817183}, author = {Paragh, György and Zilahi, Péter and Szentimrei, Réka and Lőrincz, Hajnalka and Kolozsvári, László and Harangi, Mariann}, journal-iso = {METABOLIZMUS}, journal = {METABOLIZMUS}, volume = {22}, unique-id = {34817183}, issn = {1589-7311}, year = {2024}, pages = {16-22} } @article{MTMT:34564621, title = {Serum afamin and its implications in adult growth hormone deficiency: a prospective GH-withdrawal study}, url = {https://m2.mtmt.hu/api/publication/34564621}, author = {Ratku, Balázs and Lőrincz, Hajnalka and Bak-Csiha, Sára and Sebestyén, Veronika and Berta, Eszter and Bodor, Miklós and Nagy, Endre and Szabó, Zoltán and Harangi, Mariann and Somodi, Sándor}, doi = {10.3389/fendo.2024.1348046}, journal-iso = {FRONT ENDOCRINOL}, journal = {FRONTIERS IN ENDOCRINOLOGY}, volume = {15}, unique-id = {34564621}, issn = {1664-2392}, year = {2024}, eissn = {1664-2392}, orcid-numbers = {Somodi, Sándor/0000-0002-3615-2300} } @article{MTMT:34738471, title = {ELEVATED SPHINGOSINE 1-PHOSPHATE LEVEL IN FAMILIAL HYPERCHOLESTEROLEMIC PATIENTS}, url = {https://m2.mtmt.hu/api/publication/34738471}, author = {Juhász, Lilla and Lőrincz, Hajnalka and Szentpéteri, Anita and Nádró, Bíborka and Varga, E. and Paragh, György and Harangi, M.}, journal-iso = {ATHEROSCLEROSIS}, journal = {ATHEROSCLEROSIS}, volume = {379}, unique-id = {34738471}, issn = {0021-9150}, year = {2023}, eissn = {1879-1484}, pages = {S118-S118} } @article{MTMT:34738136, title = {INVESTIGATION OF FLOW-MEDIATED DILATATION, CAROTID ARTERY INTIMA- MEDIA THICKNESS AND ARTERIAL STIFFNESS IN SYSTEMIC LUPUS ERYTHEMATOSUS PATIENTS}, url = {https://m2.mtmt.hu/api/publication/34738136}, author = {Diószegi, Ágnes and Lőrincz, Hajnalka and Kaali, E. and Harangi, Mariann and Tarr, Tünde}, journal-iso = {ATHEROSCLEROSIS}, journal = {ATHEROSCLEROSIS}, volume = {379}, unique-id = {34738136}, issn = {0021-9150}, year = {2023}, eissn = {1879-1484}, pages = {S152-S152} } @article{MTMT:34732660, title = {CORRELATIONS BETWEEN SERUM AFAMIN AND LIPID PARAMETERS IN OBESE TYPE 2 DIABETIC PATIENTS}, url = {https://m2.mtmt.hu/api/publication/34732660}, author = {Lőrincz, Hajnalka and Ratku, Balázs and Ötvös, T. and Szentpéteri, Anita and Seres, Ildikó and Paragh, György and Harangi, Mariann and Somodi, Sándor}, journal-iso = {ATHEROSCLEROSIS}, journal = {ATHEROSCLEROSIS}, volume = {379}, unique-id = {34732660}, issn = {0021-9150}, year = {2023}, eissn = {1879-1484}, pages = {S104-S104}, orcid-numbers = {Somodi, Sándor/0000-0002-3615-2300} } @article{MTMT:34729478, title = {Increased serum PEDF levels and altered lipid profile after renal transplantation in patients with end-stage renal disease}, url = {https://m2.mtmt.hu/api/publication/34729478}, author = {Szentimrei, R. and Lőrincz, Hajnalka and Szentpéteri, Anita and Varga, V.E. and Harangi, Mariann and Seres, I. and P. Szabó, Réka and Nemes, Balázs and Paragh, György}, doi = {10.1016/j.atherosclerosis.2023.06.534}, journal-iso = {ATHEROSCLEROSIS}, journal = {ATHEROSCLEROSIS}, volume = {379}, unique-id = {34729478}, issn = {0021-9150}, year = {2023}, eissn = {1879-1484}, pages = {S157-S157} } @article{MTMT:34495932, title = {A CoQ10 szerepe a kardiológiai betegségek megelőzésében és progressziójának csökkenésében}, url = {https://m2.mtmt.hu/api/publication/34495932}, author = {Paragh, György and Szentimrei, Réka and Juhász, Imre Zoltán and Lőrincz, Hajnalka and Harangi, Mariann}, journal-iso = {METABOLIZMUS}, journal = {METABOLIZMUS}, volume = {21}, unique-id = {34495932}, issn = {1589-7311}, year = {2023}, pages = {175-182} } @article{MTMT:34483385, title = {Gender-Dependent Associations between Serum Betatrophin Levels and Lipoprotein Subfractions in Diabetic and Nondiabetic Obese Patients}, url = {https://m2.mtmt.hu/api/publication/34483385}, author = {Lőrincz, Hajnalka and Bak-Csiha, Sára and Ratku, Balázs and Somodi, Sándor and Sztanek, Ferenc and Seres, Ildikó and Paragh, György and Harangi, Mariann}, doi = {10.3390/ijms242216504}, journal-iso = {INT J MOL SCI}, journal = {INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES}, volume = {24}, unique-id = {34483385}, issn = {1661-6596}, abstract = {Betatrophin, also known as angiopoietin-like protein 8 (ANGPTL8), mainly plays a role in lipid metabolism. To date, associations between betatrophin and lipoprotein subfractions are poorly investigated. For this study, 50 obese patients with type 2 diabetes (T2D) and 70 nondiabetic obese (NDO) subjects matched in gender, age, and body mass index (BMI) as well as 49 gender- and age-matched healthy, normal-weight controls were enrolled. Serum betatrophin levels were measured with ELISA, and lipoprotein subfractions were analyzed using Lipoprint gel electrophoresis. Betatrophin concentrations were found to be significantly higher in the T2D and NDO groups compared to the controls in all subjects and in females, but not in males. We found significant positive correlations between triglyceride, very low density lipoprotein (VLDL), large LDL (low density lipoprotein), small LDL, high density lipoprotein (HDL) -6-10 subfractions, and betatrophin, while negative correlations were detected between betatrophin and IDL, mean LDL size, and HDL-1-5. Proportion of small HDL was the best predictor of betatrophin in all subjects. Small LDL and large HDL subfractions were found to be the best predictors in females, while in males, VLDL was found to be the best predictor of betatrophin. Our results underline the significance of serum betatrophin measurement in the cardiovascular risk assessment of obese patients with and without T2D, but gender differences might be taken into consideration.}, year = {2023}, eissn = {1422-0067}, orcid-numbers = {Somodi, Sándor/0000-0002-3615-2300} } @article{MTMT:34215397, title = {Decreased Serum Stromal Cell-Derived Factor-1 in Patients with Familial Hypercholesterolemia and Its Strong Correlation with Lipoprotein Subfractions}, url = {https://m2.mtmt.hu/api/publication/34215397}, author = {Juhász, Lilla and Lőrincz, Hajnalka and Szentpéteri, Anita and Tóth, Nóra and Varga, Éva and Paragh, György and Harangi, Mariann}, doi = {10.3390/ijms242015308}, journal-iso = {INT J MOL SCI}, journal = {INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES}, volume = {24}, unique-id = {34215397}, issn = {1661-6596}, abstract = {Stromal cell-derived factor-1 (SDF-1) is a chemokine that exerts multifaceted roles in atherosclerosis. However, its association with hyperlipidemia is contradictory. To date, serum SDF-1 and its correlations with lipid fractions and subfractions in heterozygous familial hypercholesterolemia (HeFH) have not been investigated. Eighty-one untreated patients with HeFH and 32 healthy control subjects were enrolled in the study. Serum SDF-1, oxidized LDL (oxLDL) and myeloperoxidase (MPO) were determined by ELISA. Lipoprotein subfractions were detected by Lipoprint. We diagnosed FH using the Dutch Lipid Clinic Network criteria. Significantly lower serum SDF-1 was found in HeFH patients compared to healthy controls. Significant negative correlations were detected between serum total cholesterol, triglycerides, LDL-cholesterol (LDL-C), apolipoprotein B100 (ApoB100) and SDF-1. Furthermore, serum SDF-1 negatively correlated with VLDL and IDL, as well as large LDL and large and intermediate HDL subfractions, while there was a positive correlation between mean LDL-size, small HDL and SDF-1. SDF-1 negatively correlated with oxLDL and MPO. A backward stepwise multiple regression analysis showed that the best predictors of serum SDF-1 were VLDL and oxLDL. The strong correlation of SDF-1 with lipid fractions and subfractions highlights the potential common pathways of SDF-1 and lipoprotein metabolism, which supports the role of SDF-1 in atherogenesis.}, year = {2023}, eissn = {1422-0067}, orcid-numbers = {Varga, Éva/0000-0003-2716-0541} } @article{MTMT:34214638, title = {Assessment of amino-terminal C-type natriuretic peptide serum level and its correlation with high-density lipoprotein structure and function in patients with end stage renal disease before and after kidney transplantation}, url = {https://m2.mtmt.hu/api/publication/34214638}, author = {Szentimrei, R. and Lőrincz, Hajnalka and Szentpéteri, Anita and Varga, V.E. and Seres, Ildikó and Varga, Éva and Nemes, Balázs and Harangi, Mariann and Paragh, György}, doi = {10.1016/j.cbi.2023.110749}, journal-iso = {CHEM-BIOL INTERACT}, journal = {CHEMICO-BIOLOGICAL INTERACTIONS}, volume = {385}, unique-id = {34214638}, issn = {0009-2797}, year = {2023}, eissn = {1872-7786}, orcid-numbers = {Varga, Éva/0000-0003-2716-0541} }