@article{MTMT:34476284, title = {Regeneration of Intrabony Defects Using a Novel Magnesium Membrane}, url = {https://m2.mtmt.hu/api/publication/34476284}, author = {Hangyási, Dávid Botond and Körtvélyessy, Győző and Blaskovic, Marko and Rider, Patrick and Rogge, Svenja and Siber, Stjepan and Kacarevic, Zeljka Peric and Candrlic, Marija}, doi = {10.3390/medicina59112018}, journal-iso = {MED LITH}, journal = {MEDICINA-LITHUANIA}, volume = {59}, unique-id = {34476284}, issn = {1010-660X}, abstract = {Background and Objectives: Due to their specific morphology, the regeneration of intrabony defects (IBDs) represents one of the greatest challenges for clinicians. Based on the specific properties of a magnesium membrane, a new approach for the surgical treatment of IBD was developed. The surgical procedure was described using a series of three cases. Materials and Methods: The patients were healthy individuals suffering from a severe form of periodontitis associated with IBD. Based on radiographic examination, the patients had interproximal bone loss of at least 4 mm. Due to its good mechanical properties, it was easy to cut and shape the magnesium membrane into three different shapes to treat the specific morphology of each IBD. In accordance with the principles of guided bone regeneration, a bovine xenograft was used to fill the IBD in all cases. Results: After a healing period of 4 to 6 months, successful bone regeneration was confirmed using radiological analysis. The periodontal probing depth (PPD) after healing showed a reduction of 1.66 +/- 0.29 mm. Conclusions: Overall, the use of the different shapes of the magnesium membrane in the treatment of IBD resulted in a satisfactory functional and esthetic outcome.}, year = {2023}, eissn = {1648-9144}, orcid-numbers = {Kacarevic, Zeljka Peric/0000-0002-8250-723X} } @article{MTMT:34124966, title = {Evaluation between Biodegradable Magnesium Metal GBR Membrane and Bovine Graft with or without Hyaluronate}, url = {https://m2.mtmt.hu/api/publication/34124966}, author = {Blašković, M. and Blašković, D. and Hangyási, Dávid Botond and Peloza, O.C. and Tomas, M. and Čandrlić, M. and Rider, P. and Mang, B. and Kačarević, Ž.P. and Trajkovski, B.}, doi = {10.3390/membranes13080691}, journal-iso = {MEMBRANES-BASEL}, journal = {MEMBRANES (BASEL)}, volume = {13}, unique-id = {34124966}, abstract = {Bone substitutes and barrier membranes are widely used in dental regeneration procedures. New materials are constantly being developed to provide the most optimal surgical outcomes. One of these developments is the addition of hyaluronate (HA) to the bovine bone graft, which has beneficial wound healing and handling properties. However, an acidic environment that is potentially produced by the HA is known to increase the degradation of magnesium metal. The aim of this study was to evaluate the potential risk for the addition of HA to the bovine bone graft on the degradation rate and hence the efficacy of a new biodegradable magnesium metal GBR membrane. pH and conductivity measurements were made in vitro for samples placed in phosphate-buffered solutions. These in vitro tests showed that the combination of the bovine graft with HA resulted in an alkaline environment for the concentrations that were used. The combination was also tested in a clinical setting. The use of the magnesium metal membrane in combination with the tested grafting materials achieved successful treatment in these patients and no adverse effects were observed in vivo for regenerative treatments with or without HA. Magnesium based biodegradable GBR membranes can be safely used in combination with bovine graft with or without hyaluronate. © 2023 by the authors.}, keywords = {MEMBRANES; DEGRADATION; Tissue regeneration; MAGNESIUM; Bone; Hyaluronic Acid; MAMMALS; Bone Substitutes; alkalinity; HYALURONATE; HYALURONATE; Bovine bone; barrier membrane; barrier membrane; immediate implantation; immediate implantation; Magnesium metal; Magnesium screw; Magnesium screw; magnesium membrane; magnesium membrane; Biodegradable magnesiums; bovine bone substitute; bovine bone substitute}, year = {2023}, eissn = {2077-0375} } @article{MTMT:34067364, title = {Guided Bone Regeneration Using a Novel Magnesium Membrane: A Literature Review and a Report of Two Cases in Humans}, url = {https://m2.mtmt.hu/api/publication/34067364}, author = {Blašković, M. and Butorac, Prpić I. and Blašković, D. and Rider, P. and Tomas, M. and Čandrlić, S. and Hangyási, Dávid Botond and Čandrlić, M. and Perić, Kačarević Ž.}, doi = {10.3390/jfb14060307}, journal-iso = {J FUNCT BIOMATER}, journal = {JOURNAL OF FUNCTIONAL BIOMATERIALS}, volume = {14}, unique-id = {34067364}, year = {2023}, eissn = {2079-4983} } @article{MTMT:34028905, title = {Static and dynamic compression load tests of conically connected, screw fixed dental abutment – implant assemblies}, url = {https://m2.mtmt.hu/api/publication/34028905}, author = {Körtvélyessy, Győző and Hangyási, Dávid Botond and Tarjányi, Tamás and Tóth, Zsolt and Matusovits, Danica and Pelsőczi-Kovács, István and Baráth, Zoltán Lajos}, doi = {10.14232/analecta.2023.3.1-12}, journal-iso = {REV FAC ENG ANALECTA TECH SZEGED}, journal = {ANALECTA TECHNICA SZEGEDINENSIA}, volume = {17}, unique-id = {34028905}, issn = {1788-6392}, year = {2023}, eissn = {2064-7964}, pages = {1-12}, orcid-numbers = {Tarjányi, Tamás/0000-0002-9481-5977; Baráth, Zoltán Lajos/0000-0003-0636-6313} } @article{MTMT:33680532, title = {Different Conical Angle Connection of Implant and Abutment Behavior: A Static and Dynamic Load Test and Finite Element Analysis Study}, url = {https://m2.mtmt.hu/api/publication/33680532}, author = {Körtvélyessy, Győző and Szabó, Árpád László and Pelsőczi-Kovács, István and Tarjányi, Tamás and Tóth, Zsolt and Kárpáti, Krisztina and Matusovits, Danica and Hangyási, Dávid Botond and Baráth, Zoltán Lajos}, doi = {10.3390/ma16051988}, journal-iso = {MATERIALS}, journal = {MATERIALS}, volume = {16}, unique-id = {33680532}, abstract = {Dental implants are artificial dental roots anchoring prosthetic restorations to replace natural teeth. Dental implant systems may have different tapered conical connections. Our research focused on the mechanical examination of implant–superstructure connections. Thirty-five samples with 5 different cone angles (24°, 35°, 55°, 75°, and 90°) were tested for static and dynamic loads, carried out by a mechanical fatigue testing machine. Fixing screws were fixed with a torque of 35 Ncm before measurements. For static loading, samples were loaded with a force of 500 N in 20 s. For dynamic loading, the samples were loaded for 15,000 cycles with a force of 250 ± 150 N. In both cases, the compression resulting from load and reverse torque was examined. At the highest compression load of the static tests, a significant difference (p = 0.021) was found for each cone angle group. Following dynamic loading, significant differences (p < 0.001) for the reverse torques of the fixing screw were also shown. Static and dynamic results showed a similar trend: under the same loading conditions, changing the cone angle—which determines the relationship between the implant and the abutment—had led to significant differences in the loosening of the fixing screw. In conclusion, the greater the angle of the implant–superstructure connection, the smaller the screw loosening due to loading, which may have considerable effects on the long-term, safe operation of the dental prosthesis.}, year = {2023}, eissn = {1996-1944}, orcid-numbers = {Tarjányi, Tamás/0000-0002-9481-5977; Baráth, Zoltán Lajos/0000-0003-0636-6313} } @article{MTMT:32995603, title = {Biodegradation of a Magnesium Alloy Fixation Screw Used in a Guided Bone Regeneration Model in Beagle Dogs}, url = {https://m2.mtmt.hu/api/publication/32995603}, author = {Rider, P. and Kačarević, Ž.P. and Elad, A. and Rothamel, D. and Sauer, G. and Bornert, F. and Windisch, Péter and Hangyási, Dávid Botond and Molnár, Bálint and Hesse, B. and Assad, M. and Witte, F.}, doi = {10.3390/ma15124111}, journal-iso = {MATERIALS}, journal = {MATERIALS}, volume = {15}, unique-id = {32995603}, year = {2022}, eissn = {1996-1944}, orcid-numbers = {Windisch, Péter/0000-0001-6891-6494; Molnár, Bálint/0000-0001-6307-4873} } @article{MTMT:32827927, title = {Analysis of a Pure Magnesium Membrane Degradation Process and Its Functionality When Used in a Guided Bone Regeneration Model in Beagle Dogs}, url = {https://m2.mtmt.hu/api/publication/32827927}, author = {Rider, P. and Kačarević, Ž.P. and Elad, A. and Rothamel, D. and Sauer, G. and Bornert, F. and Windisch, Péter and Hangyási, Dávid Botond and Molnár, Bálint and Hesse, B. and Witte, F.}, doi = {10.3390/ma15093106}, journal-iso = {MATERIALS}, journal = {MATERIALS}, volume = {15}, unique-id = {32827927}, year = {2022}, eissn = {1996-1944}, orcid-numbers = {Windisch, Péter/0000-0001-6891-6494; Molnár, Bálint/0000-0001-6307-4873} } @article{MTMT:32529185, title = {Biodegradable magnesium barrier membrane used for guided bone regeneration in dental surgery}, url = {https://m2.mtmt.hu/api/publication/32529185}, author = {Rider, Patrick and Kačarević, Željka Perić and Elad, Akiva and Tadic, Drazen and Rothamel, Daniel and Sauer, Gerrit and Bornert, Fabien and Windisch, Péter and Hangyási, Dávid Botond and Molnár, Bálint and Bortel, Emely and Hesse, Bernhard and Witte, Frank}, doi = {10.1016/j.bioactmat.2021.11.018}, journal-iso = {BIOACT MATER}, journal = {BIOACTIVE MATERIALS}, volume = {14}, unique-id = {32529185}, issn = {2452-199X}, abstract = {Barrier membranes are commonly used as part of the dental surgical technique guided bone regeneration (GBR) and are often made of resorbable collagen or non-resorbable materials such as PTFE. While collagen membranes do not provide sufficient mechanical protection of the covered bone defect, titanium reinforced membranes and non-resorbable membranes need to be removed in a second surgery. Thus, biodegradable GBR membranes made of pure magnesium might be an alternative. In this study a biodegradable pure magnesium (99.95%) membrane has been proven to have all of the necessary requirements for an optimal regenerative outcome from both a mechanical and biological perspective. After implantation, the magnesium membrane separates the regenerating bone from the overlying, faster proliferating soft tissue. During the initial healing period, the membrane maintained a barrier function and space provision, whilst retaining the positioning of the bone graft material within the defect space. As the magnesium metal corroded, it formed a salty corrosion layer and local gas cavities, both of which extended the functional lifespan of the membrane barrier capabilities. During the resorption of the magnesium metal and magnesium salts, it was observed that the membrane became surrounded and then replaced by new bone. After the membrane had completely resorbed, only healthy tissue remained. The in vivo performance study demonstrated that the magnesium membrane has a comparable healing response and tissue regeneration to that of a resorbable collagen membrane. Overall, the magnesium membrane demonstrated all of the ideal qualities for a barrier membrane used in GBR treatment.}, keywords = {MAGNESIUM; implant; bone healing; biodegradable; GBR; soft tissue healing}, year = {2022}, eissn = {2452-199X}, pages = {152-168}, orcid-numbers = {Windisch, Péter/0000-0001-6891-6494; Molnár, Bálint/0000-0001-6307-4873} } @article{MTMT:32529182, title = {Biodegradable magnesium fixation screw for barrier membranes used in guided bone regeneration}, url = {https://m2.mtmt.hu/api/publication/32529182}, author = {Kačarević, Željka Perić and Rider, Patrick and Elad, Akiva and Tadic, Drazen and Rothamel, Daniel and Sauer, Gerrit and Bornert, Fabien and Windisch, Péter and Hangyási, Dávid Botond and Molnár, Bálint and Kämmerer, Till and Hesse, Bernhard and Bortel, Emely and Bartosch, Marco and Witte, Frank}, doi = {10.1016/j.bioactmat.2021.10.036}, journal-iso = {BIOACT MATER}, journal = {BIOACTIVE MATERIALS}, volume = {14}, unique-id = {32529182}, issn = {2452-199X}, abstract = {An ideal fixation system for guided bone (GBR) regeneration in oral surgery must fulfil several criteria that includes the provision of adequate mechanical fixation, complete resorption when no longer needed, complete replacement by bone, as well as be biocompatible and have a good clinical manageability. For the first time, a biodegradable magnesium fixation screw made of the magnesium alloy WZM211 with a MgF2 coating has been designed and tested to fulfill these criteria. Adequate mechanical fixation was shown for the magnesium fixation screw in several benchtop tests that directly compared the magnesium fixation screw with an equivalent polymeric resorbable device. Results demonstrated slightly superior mechanical properties of the magnesium device in comparison to the polymeric device even after 4 weeks of degradation. Biocompatibility of the magnesium fixation screw was demonstrated in several in vitro and in vivo tests. Degradation of the magnesium screw was investigated in in vitro and in vivo tests, where it was found that the screw is resorbed slowly and completely after 52 weeks, providing adequate fixation in the early critical healing phase. Overall, the magnesium fixation screw demonstrates all of the key properties required for an ideal fixation screw of membranes used in guided bone regeneration (GBR) surgeries.}, keywords = {MAGNESIUM; implant; bone healing; biodegradable; GBR; soft tissue healing}, year = {2022}, eissn = {2452-199X}, pages = {15-30}, orcid-numbers = {Windisch, Péter/0000-0001-6891-6494; Molnár, Bálint/0000-0001-6307-4873} } @misc{MTMT:32605280, title = {Galaxis Periimplanticum Útikalauz Fogorvosoknak, avagy “A Szelíd és az Agresszív” - eredmények és gyakorlati tapasztalatok}, url = {https://m2.mtmt.hu/api/publication/32605280}, author = {Hangyási, Dávid Botond and Körtvélyessy, Győző}, unique-id = {32605280}, year = {2021} }