TY - JOUR AU - Aghasizadeh Sherbaf, Reza AU - Kaposvári, George Michel AU - Nagy, Katalin AU - Álmos, Péter Zoltán AU - Baráth, Zoltán Lajos AU - Matusovits, Danica TI - Oral Health Status and Factors Related to Oral Health in Patients with Schizophrenia: A Matched Case-Control Observational Study JF - JOURNAL OF CLINICAL MEDICINE J2 - J CLIN MED VL - 13 PY - 2024 IS - 6 PG - 13 SN - 2077-0383 DO - 10.3390/jcm13061584 UR - https://m2.mtmt.hu/api/publication/34728780 ID - 34728780 LA - English DB - MTMT ER - TY - JOUR AU - Gajdács, Márió AU - Zsoldiné Urbán, Edit AU - Péter, Pallós AU - Adrienn, Márta AU - Matusovits, Danica AU - Kárpáti, Krisztina AU - Basem, Battah AU - Helal, F. Hetta AU - Ameer, Khusro AU - Dani, Dordevic AU - Ivan, Kushkevych TI - Phenotypic characteristics of environmental Pseudomonas aeruginosa: an in vitro study on epidemiological aspects JF - ACTA BIOLOGICA SZEGEDIENSIS J2 - ACTA BIOL SZEGED VL - 67 PY - 2023 IS - 1 SP - 35 EP - 44 PG - 10 SN - 1588-385X DO - 10.14232/abs.2023.1.35-44 UR - https://m2.mtmt.hu/api/publication/34500066 ID - 34500066 LA - English DB - MTMT ER - TY - JOUR AU - Szabó, Árpád László AU - Matusovits, Danica AU - Slyteen, Haydar AU - Lakatos, Ilona Éva AU - Baráth, Zoltán Lajos TI - Biomechanical Effects of Different Load Cases with an Implant-Supported Full Bridge on Four Implants in an Edentulous Mandible: A Three-Dimensional Finite Element Analysis (3D-FEA) JF - DENTISTRY JOURNAL J2 - DENT J-BASEL VL - 11 PY - 2023 IS - 11 PG - 20 SN - 2304-6767 DO - 10.3390/dj11110261 UR - https://m2.mtmt.hu/api/publication/34314522 ID - 34314522 N1 - Department of Prosthodontics, Faculty of Dentistry, University of Szeged, Tisza Lajos krt. 64-66, Szeged, 6720, Hungary Department of Structural Mechanics, Faculty of Civil Engineering, University of Technology and Economics, Budapest, Műegyetem rkp. 3, Budapest, 1111, Hungary Export Date: 14 December 2023 Correspondence Address: Baráth, Z.; Department of Prosthodontics, Tisza Lajos krt. 64-66, Hungary; email: barath.zoltan@stoma.szote.u-szeged.hu AB - The long-term success and predictability of implant-supported restorations largely depends on the biomechanical forces (stresses) acting on implants and the surrounding alveolar bone in the mandible. The aim of our study was to investigate the biomechanical behavior of an edentulous mandible with an implant-supported full bridge on four implants under simulated masticatory forces, in the context of different loading schemes, using a three-dimensional finite element analysis (3D-FEA). A patient-specific 3D finite element model was constructed using pre- and post-implantation computer tomography (CT) images of a patient undergoing implant treatment. Simplified masticatory forces set at 300 N were exerted vertically on the denture in four different simulated load cases (LC1–LC4). Two sets of simulations for different implants and denture materials (S1: titanium and titanium; S2: titanium and cobalt-chromium, respectively) were made. Stress outputs were taken as maximum (Pmax) and minimum principal stress (Pmin) and equivalent stress (Peqv) values. The highest peak Pmax values were observed for LC2 (where the modelled masticatory force excluded the cantilevers of the denture extending behind the terminal implants), both regarding the cortical bone (S1 Pmax: 89.57 MPa, S2 Pmax: 102.98 MPa) and trabecular bone (S1 Pmax: 3.03 MPa, S2 Pmax: 2.62 MPa). Overall, LC1—where masticatory forces covered the entire mesio−distal surface of the denture, including the cantilever—was the most advantageous. Peak Pmax values in the cortical bone and the trabecular bone were 14.97–15.87% and 87.96–94.54% higher in the case of S2, respectively. To ensure the long-term maintenance and longevity of treatment for implant-supported restorations in the mandible, efforts to establish the stresses of the surrounding bone in the physiological range, with the most even stress distribution possible, have paramount importance. LA - English DB - MTMT ER - TY - JOUR AU - Körtvélyessy, Győző AU - Hangyási, Dávid Botond AU - Tarjányi, Tamás AU - Tóth, Zsolt AU - Matusovits, Danica AU - Pelsőczi-Kovács, István AU - Baráth, Zoltán Lajos TI - Static and dynamic compression load tests of conically connected, screw fixed dental abutment – implant assemblies JF - ANALECTA TECHNICA SZEGEDINENSIA J2 - REV FAC ENG ANALECTA TECH SZEGED VL - 17 PY - 2023 IS - 3 SP - 1 EP - 12 PG - 12 SN - 1788-6392 DO - 10.14232/analecta.2023.3.1-12 UR - https://m2.mtmt.hu/api/publication/34028905 ID - 34028905 N1 - Nem állapítható meg egyértelműen a levelező szerzőség.(SE, SZTE admin5, 2023.06.30.) LA - English DB - MTMT ER - TY - JOUR AU - Matusovits, Danica AU - Murlasits, Zsolt AU - Kupai, Krisztina AU - Baráth, Zoltán Lajos AU - Hsu, Linkang AU - Osváth, Péter AU - Szűcs, Miklós AU - Priksz, Dániel AU - Juhász, Béla AU - Radák, Zsolt AU - Várkonyi, Tamás AU - Pávó, Imre AU - Pósa, Anikó TI - Paclitaxel Protects against Isoproterenol-Induced Damage in Rat Myocardium: Its Heme-Oxygenase Mediated Role in Cardiovascular Research JF - ANTIOXIDANTS J2 - ANTIOXIDANTS-BASEL VL - 12 PY - 2023 IS - 5 PG - 13 SN - 2076-3921 DO - 10.3390/antiox12051129 UR - https://m2.mtmt.hu/api/publication/33856409 ID - 33856409 N1 - Megosztott első szerzőség AB - (1) Background: In cardiovascular applications, paclitaxel inhibits smooth muscle cell proliferation and migration and significantly reduces the occurrence of restenosis and target lesion revascularization. However, the cellular effects of paclitaxel in the myocardium are not well understood; (2) Methods: Wistar rats were divided into four groups: control (CTRL), isoproterenol (ISO) treated (1 mg/kg) and two groups treated with paclitaxel (PAC), which was administrated (10 mg/kg/day) for 5 days by gavage/per os alone or in combination (ISO + PAC) 3 weeks after ISO treatment. Ventricular tissue was harvested 24 h later for measurements of heme oxygenase (HO-1), reduced glutathione (GSH), oxidized glutathione (GSSG), superoxide dismutase (SOD), NF-κB, TNF-α and myeloperoxidase (MPO); (3) Results: HO-1 protein concentration, HO-1 activity, SOD protein concentration and total glutathione significantly decreased in response to ISO treatment. When PAC was administered in conjunction with ISO, HO-1, SOD concentration and total glutathione were not different from control levels. MPO activity, NF-κB concentration and TNF-α protein concentration were significantly increased in the ISO-only group, while the levels of these molecules were restored when PAC was co-administered; (4) Conclusions: Oral administration of PAC can maintain the expression of important antioxidants, anti-inflammatory molecules, HO-1, SOD and GSH, and suppress the production of TNF-α, MPO and NF-κB, which are involved in myocardial damage. The principal component of this cellular defense seems to be the expression of HO-1. LA - English DB - MTMT ER - TY - JOUR AU - Körtvélyessy, Győző AU - Szabó, Árpád László AU - Pelsőczi-Kovács, István AU - Tarjányi, Tamás AU - Tóth, Zsolt AU - Kárpáti, Krisztina AU - Matusovits, Danica AU - Hangyási, Dávid Botond AU - Baráth, Zoltán Lajos TI - Different Conical Angle Connection of Implant and Abutment Behavior: A Static and Dynamic Load Test and Finite Element Analysis Study JF - MATERIALS J2 - MATERIALS VL - 16 PY - 2023 IS - 5 PG - 19 SN - 1996-1944 DO - 10.3390/ma16051988 UR - https://m2.mtmt.hu/api/publication/33680532 ID - 33680532 N1 - Department of Oral Biology and Experimental Dental Research, Faculty of Dentistry, University of Szeged, Tisza Lajos krt. 64-66, Szeged, H-6720, Hungary Department of Prosthodontics, Faculty of Dentistry, University of Szeged, Tisza Lajos krt. 64-66, Szeged, H-6720, Hungary Department of Medical Physics and Informatics, Albert Szent-Györgyi Medical School, Faculty of Science and Informatics, University of Szeged, Korányi fasor 9, Szeged, H-6720, Hungary Department of Orthodontics and Pediatric Dentistry, Faculty of Dentistry, University of Szeged, Tisza Lajos krt. 64-66, Szeged, H-6720, Hungary Department of Periodontology, Faculty of Dentistry, University of Szeged, Tisza Lajos krt. 64-66, Szeged, H-6720, Hungary Export Date: 9 May 2023 Correspondence Address: Baráth, Z.; Department of Prosthodontics, Tisza Lajos krt. 64-66, Hungary; email: barath.zoltan@stoma.szote.u-szeged.hu Funding details: Szegedi Tudományegyetem, SZTE Funding text 1: The authors are thankful for the support of Botond Veres, and the Study Group for Dental Research Methodology and Health Sciences, University of Szeged. AB - Dental implants are artificial dental roots anchoring prosthetic restorations to replace natural teeth. Dental implant systems may have different tapered conical connections. Our research focused on the mechanical examination of implant–superstructure connections. Thirty-five samples with 5 different cone angles (24°, 35°, 55°, 75°, and 90°) were tested for static and dynamic loads, carried out by a mechanical fatigue testing machine. Fixing screws were fixed with a torque of 35 Ncm before measurements. For static loading, samples were loaded with a force of 500 N in 20 s. For dynamic loading, the samples were loaded for 15,000 cycles with a force of 250 ± 150 N. In both cases, the compression resulting from load and reverse torque was examined. At the highest compression load of the static tests, a significant difference (p = 0.021) was found for each cone angle group. Following dynamic loading, significant differences (p < 0.001) for the reverse torques of the fixing screw were also shown. Static and dynamic results showed a similar trend: under the same loading conditions, changing the cone angle—which determines the relationship between the implant and the abutment—had led to significant differences in the loosening of the fixing screw. In conclusion, the greater the angle of the implant–superstructure connection, the smaller the screw loosening due to loading, which may have considerable effects on the long-term, safe operation of the dental prosthesis. LA - English DB - MTMT ER - TY - JOUR AU - Matthew, Gavino Donadu AU - Stefania, Zanetti AU - Basem, Battah AU - Helal, F. Hetta AU - Matusovits, Danica AU - Kárpáti, Krisztina AU - Virág, Finta AU - Berta, Csontos AU - Anna, Kuklis AU - Fruzsina, Szikora AU - Adrienn, Csegény AU - Lea, Szalma AU - Eszter, Major AU - Ivan, Kushkevych AU - Gajdács, Márió TI - Drug repurposing in the context of common bacterial pathogens: insights from an in vitro study JF - ACTA BIOLOGICA SZEGEDIENSIS J2 - ACTA BIOL SZEGED VL - 66 PY - 2022 IS - 2 SP - 140 EP - 149 PG - 10 SN - 1588-385X DO - 10.14232/abs.2022.2.140-149 UR - https://m2.mtmt.hu/api/publication/33731495 ID - 33731495 N1 - Hospital Pharmacy, Azienda Ospedaliero Universitaria di Sassari, Sassari, 07100, Italy Department of Biomedical Sciences, University of Sassari, Sassari, 07100, Italy Department of Biochemistry and Microbiology, Faculty of Pharmacy, Syrian Private University (SPU), Damascus, 36822, Syrian Arab Republic Department of Medical Microbiology and Immunology, Faculty of Medicine, Assiut University, Assiut, 7 71515, Egypt Department of Prosthodontics, Faculty of Dentistry, University of Szeged, Szeged, 6720, Hungary Department of Orthodontics and Pediatric Dentistry, Faculty of Dentistry, University of Szeged, Szeged, 6720, Hungary Department of Oral Biology and Experimental Dental Research, Faculty of Dentistry, University of Szeged, Szeged, 6720, Hungary Department of Experimental Biology, Faculty of Science, Masaryk University, Brno, 62500, Czech Republic Export Date: 5 October 2023 CODEN: ABSCC Correspondence Address: Gajdács, M.; Department of Oral Biology and Experimental Dental Research, Hungary; email: mariopharma92@gmail.com Chemicals/CAS: acetylcysteine, 616-91-1; acetylsalicylic acid, 493-53-8, 50-78-2, 53663-74-4, 53664-49-6, 63781-77-1; aciclovir, 59277-89-3, 69657-51-8; allopurinol, 315-30-0, 17795-21-0; alpha tocopherol, 1406-18-4, 1406-70-8, 52225-20-4, 58-95-7, 59-02-9; amantadine, 665-66-7, 768-94-5; ambroxol, 18683-91-5, 23828-92-4; amitriptyline, 50-48-6, 549-18-8; ascorbic acid, 134-03-2, 15421-15-5, 50-81-7; atorvastatin, 134523-00-5, 134523-03-8, 110862-48-1; atracurium besilate, 64228-79-1, 64228-81-5; azelastine, 58581-89-8, 79307-93-0, 37932-96-0; caffeine, 58-08-2; carbamazepine, 298-46-4, 8047-84-5; ceftriaxone, 73384-59-5, 74578-69-1, 104376-79-6; celecoxib, 169590-42-5; cetirizine, 83881-51-0, 83881-52-1, 163837-48-7; chlorzoxazone, 95-25-0; cidofovir, 113852-37-2; ciprofloxacin, 85721-33-1, 86393-32-0, 128074-72-6, 128074-76-0, 192934-52-4, 93107-08-5, 86483-48-9, 96186-80-0; clotrimazole, 23593-75-1; cyanocobalamin, 53570-76-6, 68-19-9, 8064-09-3; cyclophosphamide, 50-18-0, 6055-19-2; diclofenac, 15307-79-6, 15307-86-5; diclofenac epolamine, 119623-66-4; dipyrone, 50567-35-6, 5907-38-0, 68-89-3; enalapril maleate, 76095-16-4; etodolac, 41340-25-4, 87226-41-3, 87249-11-4; famotidine, 76824-35-6; fluconazole, 86386-73-4, 123631-92-5; fluorouracil, 51-21-8; fluoxetine, 54910-89-3, 56296-78-7, 59333-67-4, 57226-07-0; gabapentin, 60142-96-3; gemcitabine, 103882-84-4, 95058-81-4; gentamicin, 1392-48-9, 1403-66-3, 1405-41-0; guaifenesin, 93-14-1; ibuprofen, 15687-27-1, 79261-49-7, 31121-93-4, 527688-20-6; imipramine, 113-52-0, 50-49-7; indometacin, 53-86-1, 74252-25-8, 7681-54-1; ivermectin, 70288-86-7; lidocaine, 137-58-6, 24847-67-4, 56934-02-2, 73-78-9; mebendazole, 31431-39-7; metformin, 1115-70-4, 657-24-9; methotrexate, 15475-56-6, 59-05-2, 7413-34-5, 7532-09-4, 6745-93-3, 51865-79-3, 60388-53-6; metoprolol succinate, 98418-47-4; nimesulide, 51803-78-2; paracetamol, 103-90-2; phenelzine, 156-51-4, 51-71-8; prazosin, 19216-56-9, 19237-84-4; prilocaine, 1786-81-8, 721-50-6; probenecid, 57-66-9; propafenone, 34183-22-7, 54063-53-5; pyridoxine, 12001-77-3, 58-56-0, 65-23-6, 8059-24-3; retinoic acid, 302-79-4; risperidone, 106266-06-2; salbutamol, 18559-94-9, 35763-26-9; sertraline, 79617-96-2, 79559-97-0; simvastatin, 79902-63-9; sitagliptin, 486460-32-6, 654671-78-0, 654671-77-9, 2088771-60-0, 486459-71-6; suxamethonium, 306-40-1, 71-27-2; terbinafine, 91161-71-6, 78628-80-5, 176168-78-8, 78628-81-6; thiamine, 59-43-8, 67-03-8; topotecan, 119413-54-6, 123948-87-8, 1228035-86-6; valproic acid, 1069-66-5, 99-66-1; valsartan, 137862-53-4; verapamil, 152-11-4, 52-53-9; vincristine, 57-22-7; vitamin K group, 12001-79-5; xylometazoline, 1218-35-5, 526-36-3; zidovudine, 30516-87-1 Manufacturers: Ebewe, Australia; Labaz, France; Egis, Hungary; Glaxo SmithKline, Hungary; Pfizer, Hungary; Richter, Hungary; csc, India; Teva, Israel; Baxter, United States; Sigma Aldrich, United States Funding details: Nemzeti Kutatási, Fejlesztési és Innovaciós Alap, NKFIA Funding text 1: V.F. was supported by the ÚNKP-22-2-SZTE-101 “New National Excellence Program” of the Ministry for Culture and Innovation from the source of the National Research, Development and Innovation Fund. M.G. would like to acknowledge the support of the ESCMID’s “30 under 30” Award. LA - English DB - MTMT ER - TY - JOUR AU - Baráth, Zoltán Lajos AU - Stájer, Anette AU - Gajdács, Márió AU - Madléna, Melinda AU - Kárpáti, Krisztina AU - Matusovits, Danica TI - Szegedi Fogorvosnapok JF - FOGORVOSI SZEMLE J2 - FOGORV SZLE VL - 115 PY - 2022 IS - 4 SP - 208 EP - 213 PG - 6 SN - 0015-5314 UR - https://m2.mtmt.hu/api/publication/33366715 ID - 33366715 AB - Bevezetés: Kutatásunkban arra kerestük a választ, hogy két eltérő töméstechnika esetében van-e különbség a rövidüvegszál megerősítésű kompozit (short fiber-reinforced composite, SFRC) tömőanyag zsugorodása miatt kialakult repedésekszámában.Anyag és módszer: Két csoportban, 20-20 extrahált bölcsességfogba standardizált nagyságú MOD üreget preparáltunk,majd a fogakat az alábbiak szerint restauráltuk SFRC-vel: 1. csoportnál bulk, rétegzés nélküli technikával, 2. csoportbanpedig ferde rétegzéssel 2 mm vastag rétegekben. Mindegyik minta esetén az SFRC-t 1 mm kompozittal fedtük.A tömés elkészítését követően D-Light Pro lámpával megvizsgáltuk a fogzománcot, és a keletkezett repedések számátrögzítettük. Az összrepedésszámot egy hét elteltével is rögzítettük.Eredmények: A két töméstechnika között az eltérés nem szignifikáns a repedésszám tekintetében. 1 héttel későbba bulk, rétegzés nélküli csoportban 4,95 (340%-os növekedés), a rétegzéses csoportban 4,30 (410%-os növekedés) voltaz átlagos repedésszám. Ez a korábbi adatokhoz képest szignifikáns eltérés (p = 0,000). A két töméstechnika közötta végső összrepedésszám tekintetében nem tapasztaltunk szignifikáns eltérést.Következtetések: SFRC anyag esetén a vizsgált két töméstechnikával közel azonos mértékű repedésképződés jönlétre, és mindkét esetben jelentősen megnő a repedések száma a posztpolimerizációs időszakban. LA - Hungarian DB - MTMT ER - TY - JOUR AU - Baráth, Zoltán Lajos AU - Heltai, Nóra AU - Kereszty, Éva Margit AU - Ildikó, Kiss AU - Gajdács, Márió AU - Práger, Nándor Tamás AU - Kárpáti, Krisztina AU - Matusovits, Danica TI - Copper Accumulation in the Lips of Brass Players: Case Report of a Rare Phenomenon. [case report] TS - [case report] JF - DENTISTRY JOURNAL J2 - DENT J-BASEL VL - 10 PY - 2022 IS - 11 PG - 10 SN - 2304-6767 DO - 10.3390/dj10110203 UR - https://m2.mtmt.hu/api/publication/33194152 ID - 33194152 N1 - Szövegében 3 oldalnál hosszabb esetismertetés, ezért besorolása szakcikk az MTA V. Osztályának ajánlása alapján. (SE, SZTE admin5) LA - English DB - MTMT ER - TY - CONF AU - Gajdács, Márió AU - Behzadi, Payam AU - Pallós, Péter AU - Ónodi, Boglárka AU - Stájer, Anette AU - Matusovits, Danica AU - Kárpáti, Krisztina AU - Burián, Katalin AU - Zanetti, Stefania AU - Donadu, Gavino Mattew ED - Baráth, Zoltán Lajos ED - Stájer, Anette ED - Madléna, Melinda ED - Matusovits, Danica ED - Kárpáti, Krisztina ED - Gajdács, Márió TI - Van-e összefüggés a biofilm-termelés és az antibiotikum-rezisztens fenotípus között? In vitro vizsgálatok Pseudomonas aeruginosa törzseken T2 - Szegedi Fogorvosnapok 2022. Szegedi Fogorvos Találkozó és Tudományos Konferencia, Magyar Gyermekfogászati és Fogszabályozási Társaság IX. Tóth Pál Vándorgyűlés PB - Szegedi Tudományegyetem Fogorvostudományi Kar C1 - Szeged SN - 9786150161211 PY - 2022 SP - 36 EP - 37 PG - 2 UR - https://m2.mtmt.hu/api/publication/33118465 ID - 33118465 LA - Hungarian DB - MTMT ER -