@article{MTMT:34667626, title = {Socio-economic Implications of Banning Conventional Farrowing Crates in EU Pig Farming: A CAPRI-based Scenario Analysis}, url = {https://m2.mtmt.hu/api/publication/34667626}, author = {Potori, Norbert and HIMICS, Mihaly and WITZKE, Peter and Szabó, Zsolt and SAVOLY, Janos and Egri, Edit}, doi = {10.7896/j.2584}, journal-iso = {STUD AGRIC ECON}, journal = {STUDIES IN AGRICULTURAL ECONOMICS}, volume = {125}, unique-id = {34667626}, issn = {1418-2106}, year = {2023}, eissn = {2063-0476}, pages = {136-142}, orcid-numbers = {Potori, Norbert/0000-0003-0619-0215; Szabó, Zsolt/0000-0002-2902-743X} } @article{MTMT:33743491, title = {Embeddedness of Hungarian pig prices in the European pork market: a volatility spillover and partial wavelet coherence study}, url = {https://m2.mtmt.hu/api/publication/33743491}, author = {Szabó, Zsolt and Szenderák, János and Szili, Viktor and Egri, Edit and Molnár, Zsuzsa}, doi = {10.7896/j.2425}, journal-iso = {STUD AGRIC ECON}, journal = {STUDIES IN AGRICULTURAL ECONOMICS}, volume = {125}, unique-id = {33743491}, issn = {1418-2106}, year = {2023}, eissn = {2063-0476}, pages = {13-23}, orcid-numbers = {Szabó, Zsolt/0000-0002-2902-743X} } @article{MTMT:33031938, title = {Putrescine Intensifies Glu/GABA Exchange Mechanism and Promotes Early Termination of Seizures}, url = {https://m2.mtmt.hu/api/publication/33031938}, author = {Kovács, Zsolt and Skatchkov, Serguei N. and Szabó, Zsolt and Qahtan, Saif and Méndez-González, Miguel P. and Malpica-Nieves, Christian J. and Eaton, Misty J. and Kardos, Julianna and Héja, László}, doi = {10.3390/ijms23158191}, journal-iso = {INT J MOL SCI}, journal = {INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES}, volume = {23}, unique-id = {33031938}, issn = {1661-6596}, year = {2022}, eissn = {1422-0067}, orcid-numbers = {Kovács, Zsolt/0000-0001-8571-5686; Szabó, Zsolt/0000-0002-2902-743X; Méndez-González, Miguel P./0000-0003-0079-4042; Malpica-Nieves, Christian J./0000-0001-6778-408X} } @article{MTMT:32612048, title = {Connexons coupling to gap junction channel: Potential role for extracellular protein stabilization centers}, url = {https://m2.mtmt.hu/api/publication/32612048}, author = {Héja, László and Simon, Ágnes and Szabó, Zsolt and Kardos, Julianna}, doi = {10.3390/biom12010049}, journal-iso = {BIOMOLECULES}, journal = {BIOMOLECULES}, volume = {12}, unique-id = {32612048}, issn = {2218-273X}, abstract = {Connexin (Cx) proteins establish intercellular gap junction channels (Cx GJCs) through coupling of two apposed hexameric Cx hemichannels (Cx HCs, connexons). Pre-and post-GJ interfaces consist of extracellular EL1 and EL2 loops, each with three conserved cysteines. Previously, we reported that known peptide inhibitors, mimicking a variety of Cx43 sequences, appear non-selective when binding to homomeric Cx43 vs. Cx36 GJC homology model subtypes. In pursuit of finding potentially Cx subtype-specific inhibitors of connexon-connexon coupling, we aimed at to understand better how the GJ interface is formed. Here we report on the discovery of Cx GJC subtype-specific protein stabilization centers (SCs) featuring GJ interface architecture. First, the Cx43 GJC homology model, embedded in two opposed membrane bilayers, has been devised. Next, we endorsed the fluctuation dynamics of SCs of the interface domain of Cx43 GJC by applying standard molecular dynamics under open and closed cystine disulfide bond (CS-SC) preconditions. The simulations confirmed the major role of of the unique trans-GJ SC pattern comprising conserved (55N, 56T) and non-conserved (57Q) residues of the apposed EL1 loops in the stabilization of the GJC complex. Importantly, clusters of SC patterns residing close to the GJ interface domain appear to orient the interface formation via the numerous SCs between EL1 and EL2. These include central54CS-S198C or61CS-S192C contacts with residues 53R, 54C, 55N, 197D, 199F or 64V, 191P, respectively. In addition, we revealed that GJC interface formation is favoured when the psi dihedral angle of the nearby 193P residue is stable around 180◦ and the interface SCs disappear when this angle moves to the 0◦ to −45◦ range. The potential of the association of non-conserved residues with SC motifs in connexon-connexon coupling makes the development of Cx subtype-specific inhibitors viable. © 2021 by the authors. Licensee MDPI, Basel, Switzerland.}, keywords = {ARTICLE; human; membrane protein; nonhuman; PROTEIN FUNCTION; molecular dynamics; computer model; gap junction protein; disulfide bond; Connexin 43; Cystine; bilayer membrane; connexon; Close/open disulfide bonds precon-ditions; Cx43 GJC with two membranes; Cystine disulfide related GJ SC patterns; Fluctuation dynamics of protein stabilization centres (SCs); GJ architecture; Subtype-specific SC motifs}, year = {2022}, eissn = {2218-273X}, orcid-numbers = {Szabó, Zsolt/0000-0002-2902-743X} } @article{MTMT:32578354, title = {Critical Role of Astrocytic Polyamine and GABA Metabolism in Epileptogenesis}, url = {https://m2.mtmt.hu/api/publication/32578354}, author = {Kovács, Zsolt and Skatchkov, Serguei N. and Veh, Rüdiger W. and Szabó, Zsolt and Németh, Krisztina and Szabó, Pál Tamás and Kardos, Julianna and Héja, László}, doi = {10.3389/fncel.2021.787319}, journal-iso = {FRONT CELL NEUROSCI}, journal = {FRONTIERS IN CELLULAR NEUROSCIENCE}, volume = {15}, unique-id = {32578354}, issn = {1662-5102}, year = {2022}, eissn = {1662-5102}, orcid-numbers = {Kovács, Zsolt/0000-0001-8571-5686; Szabó, Zsolt/0000-0002-2902-743X; Szabó, Pál Tamás/0000-0003-2260-4641} } @article{MTMT:31971626, title = {Dual Role for Astroglial Copper-Assisted Polyamine Metabolism during Intense Network Activity}, url = {https://m2.mtmt.hu/api/publication/31971626}, author = {Szabó, Zsolt and Péter, Márton and Héja, László and Kardos, Julianna}, doi = {10.3390/biom11040604}, journal-iso = {BIOMOLECULES}, journal = {BIOMOLECULES}, volume = {11}, unique-id = {31971626}, issn = {2218-273X}, year = {2021}, eissn = {2218-273X}, orcid-numbers = {Szabó, Zsolt/0000-0002-2902-743X; Kardos, Julianna/0000-0001-9873-7155} } @article{MTMT:31925857, title = {Spontaneous Ca2+ Fluctuations Arise in Thin Astrocytic Processes With Real 3D Geometry}, url = {https://m2.mtmt.hu/api/publication/31925857}, author = {Héja, László and Szabó, Zsolt and Péter, Márton and Kardos, Julianna}, doi = {10.3389/fncel.2021.617989}, journal-iso = {FRONT CELL NEUROSCI}, journal = {FRONTIERS IN CELLULAR NEUROSCIENCE}, volume = {15}, unique-id = {31925857}, issn = {1662-5102}, year = {2021}, eissn = {1662-5102}, orcid-numbers = {Szabó, Zsolt/0000-0002-2902-743X} } @article{MTMT:31096625, title = {Astrocytic gap junctions differentially affect seizures in absence and temporal lobe epilepsy models}, url = {https://m2.mtmt.hu/api/publication/31096625}, author = {Vincze, R. and Péter, Márton and Szabó, Zsolt and Kardos, Julianna and Kovács, Zsolt and Héja, László}, journal-iso = {GLIA}, journal = {GLIA}, volume = {67}, unique-id = {31096625}, issn = {0894-1491}, year = {2019}, eissn = {1098-1136}, pages = {E710-E711}, orcid-numbers = {Szabó, Zsolt/0000-0002-2902-743X; Kovács, Zsolt/0000-0001-8571-5686} } @article{MTMT:30721430, title = {Feedback adaptation of synaptic excitability via Glu:Na+ symport driven astrocytic GABA and Gln release}, url = {https://m2.mtmt.hu/api/publication/30721430}, author = {Héja, László and Simon, Ágnes and Szabó, Zsolt and Kardos, Julianna}, doi = {10.1016/j.neuropharm.2019.05.006}, journal-iso = {NEUROPHARMACOLOGY}, journal = {NEUROPHARMACOLOGY}, volume = {161}, unique-id = {30721430}, issn = {0028-3908}, year = {2019}, eissn = {1873-7064}, orcid-numbers = {Szabó, Zsolt/0000-0002-2902-743X} } @article{MTMT:30694084, title = {Molecular Plasticity of the Nucleus Accumbens Revisited—Astrocytic Waves Shall Rise}, url = {https://m2.mtmt.hu/api/publication/30694084}, author = {Kardos, Julianna and Dobolyi, Árpád and Szabó, Zsolt and Simon, Ágnes and Lourmet, Guillaume and Palkovits, Miklós and Héja, László}, doi = {10.1007/s12035-019-1641-z}, journal-iso = {MOL NEUROBIOL}, journal = {MOLECULAR NEUROBIOLOGY}, volume = {56}, unique-id = {30694084}, issn = {0893-7648}, year = {2019}, eissn = {1559-1182}, pages = {7950-7965}, orcid-numbers = {Dobolyi, Árpád/0000-0003-0397-2991; Szabó, Zsolt/0000-0002-2902-743X; Palkovits, Miklós/0000-0003-0578-0387} }