@article{MTMT:3215365, title = {Evaluation of an automated EA-IRMS method for total carbon analysis of atmospheric aerosol at HEKAL}, url = {https://m2.mtmt.hu/api/publication/3215365}, author = {Major, István and Gyökös, Brigitta and Túri, Marianna and Futó, István and Filep, Ágnes and Hoffer, András and Furu, Enikő Emese and Jull, Timothy AJ and Molnár, Mihály}, doi = {10.1007/s10874-017-9363-y}, journal-iso = {J ATMOS CHEM}, journal = {JOURNAL OF ATMOSPHERIC CHEMISTRY}, volume = {75}, unique-id = {3215365}, issn = {0167-7764}, abstract = {Comprehensive atmospheric studies have demonstrated that carbonaceous particles are one of the main components of atmospheric aerosols over Europe. The aim of our study was to establish an automated elemental analyser interfaced to a stable isotope mass spectrometer (EA-IRMS) method at the Hertelendi Laboratory of Environmental Studies (HEKAL), as a suitable method of quantification of total carbon mass in individual PM2.5 aerosol samples. Total carbon (TC) mass and simultaneous stable isotopic ratios were determined for both test standard and genuine aerosol samples. Finally, the results were compared to the ones obtained independently by an alternative sealed tube combustion method developed previously at HEKAL. The TC recovery tests of standard material prepared by the sealed tube method confirmed at least a carbon recovery yield of 92% for a broad range of carbon mass (100–2000 μg). The stable isotopic results confirmed that sealed tube method is reproducible and suitable to be used as a reference to verify our new EA-IRMS method. The EA-IRMS TC measurements of genuine aerosols gave on average 3% higher carbon recovery yield, relative to the uncorrected results of the sealed tube method. The comparison of the stable isotopic results by the two methods for aerosols also showed minimal differences. Consequently, the possibility of simultaneous TC and stable isotopic analyses makes the EA-IRMS method a very attractive alternative for continuous measurement of aerosols, with an accuracy and reliability similar to other commercial devices.}, year = {2018}, eissn = {1573-0662}, pages = {85-96}, orcid-numbers = {Major, István/0000-0003-4675-9875; Hoffer, András/0000-0002-4207-9197} } @article{MTMT:3328715, title = {The filter-loading effect by ambient aerosols in filter absorption photometers depends on the coating of the sampled particles}, url = {https://m2.mtmt.hu/api/publication/3328715}, author = {Drinovec, L and Gregoric, A and Zotter, P and Wolf, R and Anne, Bruns and Bruns, E A and Prevot, A S H and Favez, O and Sciare, J and Arnold, I J and Chakrabarty, R K and Moosmüller, H and Filep, Ágnes and Mocnik, G}, doi = {10.5194/amt-10-1043-2017}, journal-iso = {ATMOS MEAS TECH}, journal = {ATMOSPHERIC MEASUREMENT TECHNIQUES}, volume = {10}, unique-id = {3328715}, issn = {1867-1381}, year = {2017}, eissn = {1867-8548}, pages = {1043-1059} } @article{MTMT:33071937, title = {Testing of an automated online EA-IRMS method for fast and simultaneous carbon content and stable isotope measurement of aerosol samples}, url = {https://m2.mtmt.hu/api/publication/33071937}, author = {Major, István and Gyökös, Brigitta and Túri, Marianna and Futó, István and Filep, Ágnes and Hoffer, András and Molnár, Mihály}, journal-iso = {GEOPHYS RES ABSTR}, journal = {GEOPHYSICAL RESEARCH ABSTRACTS}, volume = {18}, unique-id = {33071937}, issn = {1029-7006}, year = {2016}, eissn = {1607-7962}, pages = {3843}, orcid-numbers = {Major, István/0000-0003-4675-9875} } @article{MTMT:3038231, title = {Exposure to urban PM1 in rats: development of bronchial inflammation and airway hyperresponsiveness}, url = {https://m2.mtmt.hu/api/publication/3038231}, author = {Filep, Ágnes and Fodor, Gergely and Kun-Szabó, Fruzsina and Tiszlavicz, László and Rázga, Zsolt and Bozsó, Gábor and Bozóki, Zoltán and Szabó, Gábor and Peták, Ferenc}, doi = {10.1186/s12931-016-0332-9}, journal-iso = {RESP RES}, journal = {RESPIRATORY RESEARCH}, volume = {17}, unique-id = {3038231}, issn = {1465-9921}, abstract = {BACKGROUND: Several epidemiological and laboratory studies have evidenced the fact that atmospheric particulate matter (PM) increases the risk of respiratory morbidity. It is well known that the smallest fraction of PM (PM1 - particulate matter having a diameter below 1 mum) penetrates the deepest into the airways. The ratio of the different size fractions in PM is highly variable, but in industrial areas PM1 can be significant. Despite these facts, the health effects of PM1 have been poorly investigated and air quality standards are based on PM10 and PM2.5 (PM having diameters below 10 mum and 2.5 mum, respectively) concentrations. Therefore, this study aimed at determining whether exposure to ambient PM1 at a near alert threshold level for PM10 has respiratory consequences in rats. METHODS: Rats were either exposed for 6 weeks to 100 mug/m(3) (alert threshold level for PM10 in Hungary) urban submicron aerosol, or were kept in room air. End-expiratory lung volume, airway resistance (Raw) and respiratory tissue mechanics were measured. Respiratory mechanics were measured under baseline conditions and following intravenous methacholine challenges to characterize the development of airway hyperresponsiveness (AH). Bronchoalveolar lavage fluid (BALF) was analyzed and lung histology was performed. RESULTS: No significant differences were detected in lung volume and mechanical parameters at baseline. However, the exposed rats exhibited significantly greater MCh-induced responses in Raw, demonstrating the progression of AH. The associated bronchial inflammation was evidenced by the accumulation of inflammatory cells in BALF and by lung histology. CONCLUSIONS: Our findings suggest that exposure to concentrated ambient PM1 (mass concentration at the threshold level for PM10) leads to the development of mild respiratory symptoms in healthy adult rats, which may suggest a need for the reconsideration of threshold limits for airborne PM1.}, keywords = {air pollution; airway hyperresponsiveness; lung function; Bronchial inflammation; Ambient aerosol}, year = {2016}, eissn = {1465-993X}, orcid-numbers = {Fodor, Gergely/0000-0002-4736-4966; Tiszlavicz, László/0000-0003-1134-6587; Rázga, Zsolt/0000-0003-4717-8482; Szabó, Gábor/0000-0001-6756-4677; Peták, Ferenc/0000-0001-6249-9327} } @CONFERENCE{MTMT:3073721, title = {Pulmonary consequences of concentrated atmospheric nanoparticle inhalation in rats}, url = {https://m2.mtmt.hu/api/publication/3073721}, author = {Filep, Ágnes and G H, Fodor and Kun-Szabó, Fruzsina and L, Tiszlavicz and Rázga, Zsolt and Bozóki, Zoltán and Szabó, Gábor and F, Peták}, booktitle = {European Aerosol Conference, 2015}, unique-id = {3073721}, abstract = {https://www.eac2015.it/images/DOCS/OR3-Handbook_EAC2015.pdf}, year = {2015}, orcid-numbers = {Rázga, Zsolt/0000-0003-4717-8482; Szabó, Gábor/0000-0001-6756-4677} } @CONFERENCE{MTMT:3073711, title = {Pulmonary consequences of concentrated atmospheric nanoparticle inhalation in rats}, url = {https://m2.mtmt.hu/api/publication/3073711}, author = {Filep, Ágnes and Gergely, H Fodor and Kun-Szabó, Fruzsina and László, Tiszlavicz and Rázga, Zsolt and Bozóki, Zoltán and Szabó, Gábor and Ferenc, Peták}, booktitle = {12th Multinational Congress on Microscopy}, unique-id = {3073711}, year = {2015}, orcid-numbers = {Rázga, Zsolt/0000-0003-4717-8482; Szabó, Gábor/0000-0001-6756-4677} } @techreport{MTMT:2996480, title = {Légköri aeroszol forrásainak vizsgálata fotoakusztikus spektroszkópiával. Így kutattunk mi! TÁMOP-4.2.4.A/2-11/1-2012-0001 Nemzeti Kiválóság a Konvergencia Régióban Program beszámolói}, url = {https://m2.mtmt.hu/api/publication/2996480}, author = {Filep, Ágnes}, unique-id = {2996480}, year = {2015} } @article{MTMT:2992655, title = {Source Specific Cyto- and Genotoxicity of Atmospheric Aerosol Samples}, url = {https://m2.mtmt.hu/api/publication/2992655}, author = {Filep, Ágnes and Drinovec, Luka and Palágyi, Andrea and Manczinger, László and Vágvölgyi, Csaba and Bozóki, Zoltán and Hitzenberger, Regina and Szabó, Gábor}, doi = {10.4209/aaqr.2015.03.0131}, journal-iso = {AEROSOL AIR QUAL RES}, journal = {AEROSOL AND AIR QUALITY RESEARCH}, volume = {15}, unique-id = {2992655}, issn = {1680-8584}, year = {2015}, eissn = {2071-1409}, pages = {2325-2331}, orcid-numbers = {Manczinger, László/0000-0003-1031-7522; Vágvölgyi, Csaba/0000-0003-0009-7773; Szabó, Gábor/0000-0001-6756-4677} } @book{MTMT:2869928, title = {A XII. Magyar Aeroszol Konferencia előadás-kivonatai}, url = {https://m2.mtmt.hu/api/publication/2869928}, isbn = {9789633063644}, editor = {Filep, Ágnes and Mucsiné, Égerházi Lilla}, publisher = {SZTE}, unique-id = {2869928}, year = {2015} } @CONFERENCE{MTMT:2828816, title = {Connection between optically based source apportionment and toxicity of atmospheric aerosol samples}, url = {https://m2.mtmt.hu/api/publication/2828816}, author = {Filep, Ágnes and Luka, Drinovec and Andrea, Palágyi and László, Manczinger and Vágvölgyi, Csaba and Bozóki, Zoltán and Szabó, Gábor}, booktitle = {Abstracts of the International Aerosol Conference 2014}, unique-id = {2828816}, year = {2014}, orcid-numbers = {Vágvölgyi, Csaba/0000-0003-0009-7773; Szabó, Gábor/0000-0001-6756-4677} }