TY - JOUR AU - Kelemen, Gyöngyi AU - Együd, Zsófia AU - Dobi, Ágnes AU - Varga, Linda AU - Kószó, Renáta Lilla AU - Borzási, Emőke AU - Paczona, Viktor Róbert AU - Végváry, Zoltán AU - Borzák, Ferenc AU - Fodor, Emese AU - Ócsai, Henriette AU - Baltás, Eszter AU - Oláh, Judit Magdolna AU - Hideghéty, Katalin TI - Survival Benefit of Stereotactic Radiotherapy in the Complex Management of Metastatic Melanoma JF - ANTICANCER RESEARCH J2 - ANTICANCER RES VL - 44 PY - 2024 IS - 1 SP - 205 EP - 212 PG - 8 SN - 0250-7005 DO - 10.21873/anticanres.16803 UR - https://m2.mtmt.hu/api/publication/34509121 ID - 34509121 LA - English DB - MTMT ER - TY - JOUR AU - Varga, Linda AU - Besenyi, Zsuzsanna AU - Paczona, Viktor Róbert AU - Farkas, István AU - Urbán, Szabolcs AU - Sipka, Gábor AU - Pávics, László AU - Varga, Zoltán AU - Fodor, Emese AU - Hideghéty, Katalin AU - Oláh, Judit Magdolna AU - Bajory, Zoltán AU - Maráz, Anikó TI - Prostate-specific membrane antigen-based imaging for stereotactic irradiation of low-volume progressive prostate cancer: a single-center experience JF - FRONTIERS IN ONCOLOGY J2 - FRONT ONCOL VL - 13 PY - 2023 PG - 11 SN - 2234-943X DO - 10.3389/fonc.2023.1166665 UR - https://m2.mtmt.hu/api/publication/34093322 ID - 34093322 N1 - Department of Oncotherapy, University of Szeged, Szeged, Hungary Department of Nuclear Medicine, University of Szeged, Szeged, Hungary Department of Urology, University of Szeged, Szeged, Hungary Export Date: 28 October 2023 Correspondence Address: Varga, L.; Department of Oncotherapy, Hungary; email: drvargalinda@gmail.com Correspondence Address: Besenyi, Z.; Department of Nuclear Medicine, Hungary; email: besenyi.zsuzsanna@med.u-szeged.hu Chemicals/CAS: abiraterone, 154229-19-3; docetaxel, 114977-28-5; enzalutamide, 915087-33-1 Manufacturers: GE Healthcare, United States Funding text 1: The authors express their sincere gratitude to the Institute of Isotopes Co. Ltd. for the scientific cooperation and valuable advice as well as comments. LA - English DB - MTMT ER - TY - JOUR AU - Varga, Linda AU - Torday, László AU - Hideghéty, Katalin AU - Borzási, Emőke AU - Csenki, Melinda AU - Cserháti, Adrienn AU - Deák , Bence AU - Dobi, Ágnes AU - Együd, Zsófia AU - Fodor, Emese AU - Gaál, Szilvia AU - Kelemen, Gyöngyi AU - Kószó, Renáta Lilla AU - Nagy-László, Roland AU - Paczona, Viktor Róbert AU - Pepó, Judit AU - Sántha, Dóra AU - Uhercsák, Gabriella AU - Varga, Zoltán AU - Végváry, Zoltán AU - Vasas, Béla AU - Berényi, Zsolt AU - Lázár, György ifj AU - Ábrahám, Szabolcs AU - Paszt, Attila AU - Simonka, Zsolt AU - Oláh, Judit Magdolna AU - Maráz, Anikó TI - Elérkezett a teljes neoadjuváns terápia (TNT) ideje a lokálisan előrehaladott magas rizikójú végbéltumoros betegeknél? JF - MAGYAR ONKOLÓGIA J2 - MAGYAR ONKOLÓGIA VL - 66 PY - 2022 IS - 1 SP - 71 EP - 71 PG - 1 SN - 0025-0244 UR - https://m2.mtmt.hu/api/publication/32794334 ID - 32794334 LA - Hungarian DB - MTMT ER - TY - CHAP AU - Ruskó, László AU - Capala, Marta AU - Czipczer, Vanda AU - Kolozsvári, Bernadett AU - Deák-Karancsi, Borbála AU - Czabány, Renáta AU - Gyalai, Bence AU - Tan, Tao AU - Végváry, Zoltán AU - Borzási, Emőke AU - Együd, Zsófia AU - Kószó, Renáta Lilla AU - Paczona, Viktor Róbert AU - Fodor, Emese AU - Bobb, Chad AU - Cozzini, Cristina AU - Kaushik, Sandeep AU - Darázs, Barbara AU - Verduijn, Gerda M. AU - Pearson, Rachel AU - Maxwell, Ross AU - Mccallum, Hazel AU - Hernandez Tamames, Juan AU - Hideghéty, Katalin AU - Petit, Steven AU - Wiesinger, Florian ED - Douplik, A ED - Fred, A ED - Gamboa, H TI - Deep-Learning-based Segmentation of Organs-at-Risk in the Head for MR-assisted Radiation Therapy Planning T2 - Proceedings of the 14th International Joint Conference on Biomedical Engineering Systems and Technologies PB - SciTePress CY - Setubal T3 - Biostec, ISSN 2184-4305 ; 2. PY - 2021 SP - 31 EP - 43 PG - 13 DO - 10.5220/0010235000002865 UR - https://m2.mtmt.hu/api/publication/31926981 ID - 31926981 N1 - Funding Agency and Grant Number: EIT Health [19037, 20648]; European Institute of Innovation and Technology (EIT); European Union's Horizon 2020 Research and innovation programme Funding text: This research is part of the Deep MR-only Radiation Therapy activity (project numbers: 19037, 20648) that has received funding from EIT Health. EIT Health is supported by the European Institute of Innovation and Technology (EIT), a body of the European Union receives support from the European Union's Horizon 2020 Research and innovation programme. LA - English DB - MTMT ER - TY - JOUR AU - Dobi, Ágnes AU - Darázs, Barbara AU - Fodor, Emese AU - Cserháti, Adrienn AU - Együd, Zsófia AU - Maráz, Anikó AU - László, Szilvia AU - Dodd, Leopold AU - Reisz, Zita AU - Barzó, Pál AU - Oláh, Judit Magdolna AU - Hideghéty, Katalin TI - Low Fraction Size Re-irradiation for Large Volume Recurrence of Glial Tumours JF - PATHOLOGY AND ONCOLOGY RESEARCH J2 - PATHOL ONCOL RES VL - 26 PY - 2020 IS - 4 SP - 2651 EP - 2658 PG - 8 SN - 1219-4956 DO - 10.1007/s12253-020-00868-2 UR - https://m2.mtmt.hu/api/publication/31646225 ID - 31646225 LA - English DB - MTMT ER - TY - JOUR AU - Végváry, Zoltán AU - Darázs, Barbara AU - Paczona, Viktor Róbert AU - Dobi, Ágnes AU - Reisz, Zita AU - Varga, Zoltán AU - Fodor, Emese AU - Cserháti, Adrienn AU - Oláh, Judit Magdolna AU - Kis, Dávid AU - Barzó, Pál AU - Hideghéty, Katalin TI - Adaptive Radiotherapy for Glioblastoma Multiforme – The Impact on Disease Outcome JF - ANTICANCER RESEARCH J2 - ANTICANCER RES VL - 40 PY - 2020 IS - 8 SP - 4237 EP - 4244 PG - 8 SN - 0250-7005 DO - 10.21873/anticanres.14425 UR - https://m2.mtmt.hu/api/publication/31567225 ID - 31567225 N1 - Department of Oncotherapy, University of Szeged, Szeged, Hungary ELI-ALPS Non-profit Ltd, Szeged, Hungary Department of Pathology, University of Szeged, Szeged, Hungary Department of Neurosurgery, University of Szeged, Szeged, Hungary Cited By :1 Export Date: 10 November 2020 CODEN: ANTRD Correspondence Address: Darazs, B.; Department of Oncotherapy, University of SzegedHungary; email: darazsb@gmail.com Chemicals/CAS: methylated DNA protein cysteine methyltransferase; temozolomide, 85622-93-1 Tradenames: Xio Planning System (version 4.7), Elekta, Sweden Manufacturers: Elekta, Sweden Funding details: Nemzeti Kutatási, Fejlesztési és Innovaciós Alap, NKFIA Funding details: VKSZ 12-1-2013-0012 Funding text 1: This project was supported by Analytic Healthcare Quality User Information Program of the National Research, Development and Innovation Fund, Hungarian Government, Grant VKSZ 12-1-2013-0012 and by the Szeged Foundation for Cancer Research. Funding Agency and Grant Number: Analytic Healthcare Quality User Information Program of the National Research, Development and Innovation Fund, Hungarian Government [VKSZ 12-1-20130012]; Szeged Foundation for Cancer Research Funding text: This project was supported by Analytic Healthcare Quality User Information Program of the National Research, Development and Innovation Fund, Hungarian Government, Grant VKSZ 12-1-20130012 and by the Szeged Foundation for Cancer Research. LA - English DB - MTMT ER - TY - JOUR AU - Polanek, Róbert AU - Varga, Zoltán AU - Fodor, Emese AU - Brunner, Szilvia AU - Szabó, Emilia Rita AU - Tőkés, Tünde AU - Hideghéty, Katalin TI - Improved FBX chemical dosimeter system with enhanced radiochemical yield for reference dosimetry in radiobiology and radiotherapy research JF - RADIATION PHYSICS AND CHEMISTRY: THE JOURNAL FOR RADIATION PHYSICS RADIATION CHEMISTRY AND RADIATION PROCESSING J2 - RADIAT PHYS CHEM VL - 174 PY - 2020 PG - 8 SN - 0969-806X DO - 10.1016/j.radphyschem.2020.108899 UR - https://m2.mtmt.hu/api/publication/31392882 ID - 31392882 AB - Radiation dosimetry plays important role in the reproducibility of radiobiology experiments, in the replicability of results, as well as in the successful and safe use of radiotherapy procedures. The consistency and accuracy of the applied dosimetry methods pre-define the outcomes of these applications. This paper presents a version of the well-known ferrous sulphate – benzoic acid – xylenol orange (FBX) chemical dosimeter with improved sensitivity, accuracy and precision. Sensitivity is increased due to a slight modification in composition and the preparation procedures. We use stock solutions for the preparation of the dosimeter solution, which consists of 1 mM ferrous sulphate and 16 mM benzoic acid with 0.25 mM xylenol orange added post-irradiation. The nonlinear response to the absorbed dose of this system is eliminated by the increased ferrous sulphate concentration, permitting the calculation of the absorbed dose by a linear relationship between the absorbed dose and the optical absorbance of the solution. The measured chemical yield of our dosimeter is 9.08⋅10−6mol/J for 6 MV photon beams and 6.42⋅10−6mol/J for 250 kVp x-rays. This is a 24% enhancement over the original FBX solution, which permits a finer dose resolution. The accuracy and precision of our method is assured by a well-designed and consistently used practice. A custom designed multipurpose PMMA slab phantom was used for irradiation in reference conditions. This phantom can be used for irradiation in reference conditions of dosimetric solutions, dosimetric films and chemical or biological samples. The combined standard uncertainty of this system is 1.12%, which can be improved by using an appropriate temperature correction factor. Furthermore, a working protocol has been established which allows dosimetry measurements using less than 1 mL dosimetric solutions. LA - English DB - MTMT ER - TY - JOUR AU - Dobi, Ágnes AU - Fodor, Emese AU - Maráz, Anikó AU - Együd, Zsófia AU - Cserháti, Adrienn AU - Tiszlavicz, László AU - Reisz, Zita AU - Barzó, Pál AU - Varga, Zoltán AU - Hideghéty, Katalin TI - Boost Irradiation Integrated to Whole Brain Radiotherapy in the Management of Brain Metastases JF - PATHOLOGY AND ONCOLOGY RESEARCH J2 - PATHOL ONCOL RES VL - 26 PY - 2020 IS - 1 SP - 149 EP - 157 PG - 9 SN - 1219-4956 DO - 10.1007/s12253-018-0383-y UR - https://m2.mtmt.hu/api/publication/3333259 ID - 3333259 AB - Our retrospective analysis aimed to evaluate the clinical value of dose intensification schemes: WBRT and consecutive, delayed, or simultaneous integrated boost (SIB) in brain metastasis (BM) management. Clinical data and overall survival (OS) of 468 patients with BM from various primaries treated with 10 x 3 Gy WBRT (n = 195), WBRT+ 10 x 2 Gy boost (n = 125), or simultaneously 15 x 2.2 Gy WBRT+0.7 Gy boost (n = 148) during a 6-year period were statistically analysed. Significant difference in OS could be detected with additional boost to WBRT (3.3 versus 6.5 months) and this difference was confirmed for BMs of lung cancer and melanoma and both for oligo- and multiplex lesions. The OS was prolonged for the RPA 2 and RPA3 categories, if patients received escalated dose, 4.0 vs. 7.7 months; (p = 0.002) in class RPA2 and 2.6 vs. 4.2 months; (p < 0.0001) in the class RPA 3 respectively. The significant difference in OS was also achieved with SIB. The shortened overall treatment time of SIB with lower WBRT fraction dose exhibited survival benefit over WBRT alone, and could be applied for patients developing BM even with unfavourable prognostic factors. These results warrant for further study of this approach with dose escalation using the lately available solutions for hippocampus sparing and fractionated stereotactic irradiation. The simultaneous delivery of WBRT with reduced fraction dose and boost proved to be advantageous prolonging the OS with shortened treatment time and reduced probability for cognitive decline development even for patients with poor performance status and progressing extracranial disease. LA - English DB - MTMT ER - TY - JOUR AU - Mészáros, Norbert AU - Dobi, Ágnes AU - Végváry, Zoltán AU - Torday, László AU - Fodor, Emese AU - Hideghéty, Katalin AU - Stelczer, Gábor AU - Jánváry, Zsolt Levente AU - Polgár, Csaba TI - Az első CyberKnife-on kezelt HCC-s beteg sztereotaxiás sugárkezelése – egy sikeres együttműködés története JF - MAGYAR ONKOLÓGIA J2 - MAGYAR ONKOLÓGIA VL - 63 PY - 2019 IS - 2 SP - 152 EP - 153 PG - 2 SN - 0025-0244 UR - https://m2.mtmt.hu/api/publication/31141300 ID - 31141300 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Végváry, Zoltán AU - Gal, V AU - Kószó, Renáta Lilla AU - Bányai, É AU - Fodor, Emese AU - Nagy, Zoltán AU - Varga, Zoltán AU - Kalmár, László AU - Nagy, Bence AU - Terhes, Gabriella AU - Kahán, Zsuzsanna TI - Multimodális képalkotással támogatott adaptív sugárterápia lokálisan előrehaladott méhnyakrákban JF - MAGYAR ONKOLÓGIA J2 - MAGYAR ONKOLÓGIA VL - 63 PY - 2019 IS - Suppl. 1 SP - 69 EP - 69 PG - 1 SN - 0025-0244 UR - https://m2.mtmt.hu/api/publication/30938370 ID - 30938370 LA - Hungarian DB - MTMT ER -