TY - JOUR AU - Lückl, János AU - Baker, Wesley AU - Boda, Krisztina AU - Emri, Miklós AU - YodhArjun G Yodh, Arjun G AU - Greenberg, Joel H TI - Oxyhemoglobin and cerebral blood flow transients detect infarction in rat focal brain ischemia JF - NEUROSCIENCE J2 - NEUROSCIENCE VL - 509 PY - 2023 SP - 132 EP - 144 PG - 13 SN - 0306-4522 DO - 10.1016/j.neuroscience.2022.11.028 UR - https://m2.mtmt.hu/api/publication/33286181 ID - 33286181 AB - depolarizations (SD) refer to the near-complete depolarization of neurons that is associated with brain injuries such as ischemic stroke. The present gold standard for SD monitoring in humans is invasive electrocorticography (ECoG). A promising non-invasive alternative to ECoG is diffuse optical monitoring of SD -related flow and hemoglobin transients. To investigate the clinical utility of flow and hemoglobin transients, we analyzed their association with infarction in rat focal brain ischemia. Optical images of flow, oxy-hemoglobin, and deoxy-hemoglobin were continuously acquired with Laser Speckle and Optical Intrinsic Signal imaging for 2 h after photochemically induced distal middle cerebral artery occlusion in Sprague-Dawley rats (n = 10). Imag-ing was performed through a 6 x 6 mm window centered 3 mm posterior and 4 mm lateral to Bregma. Rats were sacrificed after 24 h, and the brain slices were stained for assessment of infarction. We mapped the infarcted area onto the imaging data and used nine circular regions of interest (ROI) to distinguish infarcted from non-infarcted tissue. Transients propagating through each ROI were characterized with six parameters (negative, positive, and total amplitude; negative and positive slope; duration). Transients were also classified into three morphology types (positive monophasic, biphasic, negative monophasic). Flow transient morphology, positive amplitude, positive slope, and total amplitude were all strongly associated with infarction (p < 0.001). Associations with infarction were also observed for oxy-hemoglobin morphology, oxy-hemoglobin positive amplitude and slope, and deoxy-hemoglobin positive slope and duration (all p < 0.01). These results suggest that flow and hemoglobin transients accompanying SD have value for detecting infarction.(c) 2022 IBRO. Published by Elsevier Ltd. All rights reserved. LA - English DB - MTMT ER - TY - JOUR AU - Borbély, Katalin AU - Emri, Miklós AU - Kenessey, István AU - Tóth, Márton AU - Singer, Júlia AU - Barsi, Péter AU - Vajda, Zsolt AU - Pál, Endre AU - Tóth, Zoltán AU - Beyer, Thomas AU - Dóczi, Tamás Péter AU - Bajzik, Gábor AU - Fabó, Dániel AU - Janszky, József Vladimír AU - Jordán, Zsófia AU - Fajtai, Dániel AU - Kelemen, Anna AU - Juhos, Vera AU - Wintermark, Max AU - Nagy, Ferenc AU - Moizs, Mariann AU - Nagy , Dávid Gergő AU - Lückl, János AU - Repa, Imre TI - PET/MRI in the Presurgical Evaluation of Patients with Epilepsy: A Concordance Analysis JF - BIOMEDICINES J2 - BIOMEDICINES VL - 10 PY - 2022 IS - 5 PG - 14 SN - 2227-9059 DO - 10.3390/biomedicines10050949 UR - https://m2.mtmt.hu/api/publication/32788547 ID - 32788547 N1 - * Megosztott szerzőség LA - English DB - MTMT ER - TY - JOUR AU - Dreier, Jens P. AU - Winkler, Maren K. L. AU - Major, Sebastian AU - Horst, Viktor AU - Lublinsky, Svetlana AU - Kola, Vasilis AU - Lemale, Coline L. AU - Kang, Eun-Jeung AU - Maslarova, Anna AU - Salur, Irmak AU - Lückl, János AU - Platz, Johannes AU - Jorks, Devi AU - Oliveira-Ferreira, Ana I. AU - Schoknecht, Karl AU - Reiffurth, Clemens AU - Milakara, Denny AU - Wiesenthal, Dirk AU - Hecht, Nils AU - Dengler, Nora F. AU - Liotta, Agustin AU - Wolf, Stefan AU - Kowoll, Christina M. AU - Schulte, André P. AU - Santos, Edgar AU - Güresir, Erdem AU - Unterberg, Andreas W. AU - Sarrafzadeh, Asita AU - Sakowitz, Oliver W. AU - Vatter, Hartmut AU - Reiner, Michael AU - Brinker, Gerrit AU - Dohmen, Christian AU - Shelef, Ilan AU - Bohner, Georg AU - Scheel, Michael AU - Vajkoczy, Peter AU - Hartings, Jed A. AU - Friedman, Alon AU - Martus, Peter AU - Woitzik, Johannes TI - Spreading depolarizations in ischaemia after subarachnoid haemorrhage, a diagnostic phase III study JF - BRAIN J2 - BRAIN VL - 145 PY - 2022 IS - 4 SP - 1264 EP - 1284 PG - 21 SN - 0006-8950 DO - 10.1093/brain/awab457 UR - https://m2.mtmt.hu/api/publication/32781700 ID - 32781700 AB - Focal brain damage after aneurysmal subarachnoid haemorrhage predominantly results from intracerebral haemorrhage, and early and delayed cerebral ischaemia. The prospective, observational, multicentre, cohort, diagnostic phase III trial, DISCHARGE-1, primarily investigated whether the peak total spreading depolarization-induced depression duration of a recording day during delayed neuromonitoring (delayed depression duration) indicates delayed ipsilateral infarction. Consecutive patients (n = 205) who required neurosurgery were enrolled in six university hospitals from September 2009 to April 2018. Subdural electrodes for electrocorticography were implanted. Participants were excluded on the basis of exclusion criteria, technical problems in data quality, missing neuroimages or patient withdrawal (n = 25). Evaluators were blinded to other measures. Longitudinal MRI, and CT studies if clinically indicated, revealed that 162/180 patients developed focal brain damage during the first 2 weeks. During 4.5 years of cumulative recording, 6777 spreading depolarizations occurred in 161/180 patients and 238 electrographic seizures in 14/180. Ten patients died early; 90/170 developed delayed infarction ipsilateral to the electrodes. Primary objective was to investigate whether a 60-min delayed depression duration cut-off in a 24-h window predicts delayed infarction with >0.60 sensitivity and >0.80 specificity, and to estimate a new cut-off. The 60-min cut-off was too short. Sensitivity was sufficient [= 0.76 (95% confidence interval: 0.65-0.84), P = 0.0014] but specificity was 0.59 (0.47-0.70), i.e. <0.80 (P < 0.0001). Nevertheless, the area under the receiver operating characteristic (AUROC) curve of delayed depression duration was 0.76 (0.69-0.83, P < 0.0001) for delayed infarction and 0.88 (0.81-0.94, P < 0.0001) for delayed ischaemia (reversible delayed neurological deficit or infarction). In secondary analysis, a new 180-min cut-off indicated delayed infarction with a targeted 0.62 sensitivity and 0.83 specificity. In awake patients, the AUROC curve of delayed depression duration was 0.84 (0.70-0.97, P = 0.001) and the prespecified 60-min cut-off showed 0.71 sensitivity and 0.82 specificity for reversible neurological deficits. In multivariate analysis, delayed depression duration (beta = 0.474, P < 0.001), delayed median Glasgow Coma Score (beta = -0.201, P = 0.005) and peak transcranial Doppler (beta = 0.169, P = 0.016) explained 35% of variance in delayed infarction. Another key finding was that spreading depolarization-variables were included in every multiple regression model of early, delayed and total brain damage, patient outcome and death, strongly suggesting that they are an independent biomarker of progressive brain injury. While the 60-min cut-off of cumulative depression in a 24-h window indicated reversible delayed neurological deficit, only a 180-min cut-off indicated new infarction with >0.60 sensitivity and >0.80 specificity. Although spontaneous resolution of the neurological deficit is still possible, we recommend initiating rescue treatment at the 60-min rather than the 180-min cut-off if progression of injury to infarction is to be prevented.Focal damage after subarachnoid haemorrhage results from intracerebral haemorrhage and cerebral ischaemia. In a prospective, observational, multicentre, diagnostic phase III trial, DISCHARGE-1, Dreier et al. examine whether monitoring cortical spreading depolarizations can predict delayed infarction-and thus poor outcomes. LA - English DB - MTMT ER - TY - JOUR AU - Lemale, Coline L. AU - Lückl, János AU - Horst, Viktor AU - Reiffurth, Clemens AU - Major, Sebastian AU - Hecht, Nils AU - Woitzik, Johannes AU - Dreier, Jens P. TI - Migraine Aura, Transient Ischemic Attacks, Stroke, and Dying of the Brain Share the Same Key Pathophysiological Process in Neurons Driven by Gibbs–Donnan Forces, Namely Spreading Depolarization JF - FRONTIERS IN CELLULAR NEUROSCIENCE J2 - FRONT CELL NEUROSCI VL - 16 PY - 2022 PG - 29 SN - 1662-5102 DO - 10.3389/fncel.2022.837650 UR - https://m2.mtmt.hu/api/publication/32663200 ID - 32663200 LA - English DB - MTMT ER - TY - JOUR AU - Tóth, Márton AU - Barsi, Péter AU - Tóth, Zoltán AU - Borbély, Katalin AU - Lückl, János AU - Emri, Miklós AU - Repa, Imre AU - Janszky, József Vladimír AU - Dóczi, Tamás Péter AU - Horváth, Zsolt AU - Halász, Péter AU - Juhos, Vera AU - Trischlerné Gyimesi, Csilla AU - Bóné, Beáta AU - Kuperczkó, Diána AU - Horváth, Réka AU - Nagy, Ferenc AU - Kelemen, Anna AU - Jordán, Zsófia AU - Újvári, Ákos AU - Hagiwara, Koichi AU - Isnard, Jean AU - Pál, Endre AU - Fekésházy, Attila AU - Fabó, Dániel AU - Vajda, Zsolt TI - The role of hybrid FDG-PET/MRI on decision-making in presurgical evaluation of drug-resistant epilepsy JF - BMC NEUROLOGY J2 - BMC NEUROL VL - 21 PY - 2021 IS - 1 PG - 20 SN - 1471-2377 DO - 10.1186/s12883-021-02352-z UR - https://m2.mtmt.hu/api/publication/32219141 ID - 32219141 N1 - * Megosztott szerzőség AB - When MRI fails to detect a potentially epileptogenic lesion, the chance of a favorable outcome after epilepsy surgery becomes significantly lower (from 60 to 90% to 20-65%). Hybrid FDG-PET/MRI may provide additional information for identifying the epileptogenic zone. We aimed to investigate the possible effect of the introduction of hybrid FDG-PET/MRI into the algorithm of the decision-making in both lesional and non-lesional drug-resistant epileptic patients.In a prospective study of patients suffering from drug-resistant focal epilepsy, 30 nonlesional and 30 lesional cases with discordant presurgical results were evaluated using hybrid FDG-PET/MRI.The hybrid imaging revealed morphological lesion in 18 patients and glucose hypometabolism in 29 patients within the nonlesional group. In the MRI positive group, 4 patients were found to be nonlesional, and in 9 patients at least one more epileptogenic lesion was discovered, while in another 17 cases the original lesion was confirmed by means of hybrid FDG-PET/MRI. As to the therapeutic decision-making, these results helped to indicate resective surgery instead of intracranial EEG (iEEG) monitoring in 2 cases, to avoid any further invasive diagnostic procedures in 7 patients, and to refer 21 patients for iEEG in the nonlesional group. Hybrid FDG-PET/MRI has also significantly changed the original therapeutic plans in the lesional group. Prior to the hybrid imaging, a resective surgery was considered in 3 patients, and iEEG was planned in 27 patients. However, 3 patients became eligible for resective surgery, 6 patients proved to be inoperable instead of iEEG, and 18 cases remained candidates for iEEG due to the hybrid FDG-PET/MRI. Two patients remained candidates for resective surgery and one patient became not eligible for any further invasive intervention.The results of hybrid FDG-PET/MRI significantly altered the original plans in 19 of 60 cases. The introduction of hybrid FDG-PET/MRI into the presurgical evaluation process had a potential modifying effect on clinical decision-making.Trial registry: Scientific Research Ethics Committee of the Medical Research Council of Hungary.008899/2016/OTIG . Date of registration: 08 February 2016. LA - English DB - MTMT ER - TY - JOUR AU - Horváth, András Attila AU - Papp, Anikó AU - Zsuffa, János AU - Szűcs, Anna AU - Lückl, János AU - Radai, Ferenc AU - Nagy, Ferenc AU - Hidasi, Zoltán AU - Csukly, Gábor AU - Barcs, Gábor AU - Kamondi, Anita TI - Subclinical epileptiform activity accelerates the progression of Alzheimer’s disease: a long-term EEG study JF - CLINICAL NEUROPHYSIOLOGY J2 - CLIN NEUROPHYSIOL VL - 132 PY - 2021 IS - 8 SP - 1982 EP - 1989 PG - 8 SN - 1388-2457 DO - 10.1016/j.clinph.2021.03.050 UR - https://m2.mtmt.hu/api/publication/32007928 ID - 32007928 N1 - National Institute of Clinical Neurosciences, Department of Neurology Budapest, Hungary Semmelweis University, Department of Anatomy Histology and Embryology, Budapest, Hungary Semmelweis University, School of PhD Studies, Budapest, Hungary János Zsuffa, Zsuffa-Med Ltd., Budapest, Hungary Department of Neurology, Kaposi Mór County Hospital, Kaposvár, Hungary Semmelweis University, Department of Psychiatry and Psychotherapy, Budapest, Hungary Semmelweis University, Department of Neurology, Budapest, Hungary Cited By :40 Export Date: 31 January 2024 CODEN: CNEUF Correspondence Address: Horvath, A.A.57 Amerikai út, Hungary; email: horvath.andras1@med.semmelweis-univ.hu LA - English DB - MTMT ER - TY - GEN AU - Tóth, Márton AU - Barsi, Péter AU - Tóth, Zoltán AU - Borbély, Katalin AU - Lückl, János AU - Emri, Miklós AU - Repa, Imre AU - Janszky, Jozsef AU - Doczi, Tamas AU - Horvath, Zsolt AU - Halasz, Peter AU - Juhos, Vera AU - Gyimesi, Csilla AU - Bone, Beata AU - Kuperczkó, Diána AU - Horvath, Reka AU - Nagy, Ferenc AU - Kelemen, Anna AU - Jordan, Zsoa AU - Ujvari, Akos AU - Hagiwara, Koichi AU - Isnard, Jean AU - Pal, Endre AU - Fekésházy, Attila AU - Fabo, Daniel AU - Vajda, Zsolt TI - The Role of Hybrid FDG-PET/MRI on Decision-Making in Presurgical Evaluation of Drug-Resistant Epilepsy PY - 2020 UR - https://m2.mtmt.hu/api/publication/31686790 ID - 31686790 LA - English DB - MTMT ER - TY - JOUR AU - Cheng, Bastian AU - Boutitie, Florent AU - Nickel, Alina AU - Wouters, Anke AU - Cho, Tae-Hee AU - Ebinger, Martin AU - Endres, Matthias AU - Fiebach, Jochen B. AU - Fiehler, Jens AU - Galinovic, Ivana AU - Puig, Josep AU - Thijs, Vincent AU - Lemmens, Robin AU - Muir, Keith W. AU - Nighoghossian, Norbert AU - Pedraza, Salvador AU - Simonsen, Claus Z. AU - Gerloff, Christian AU - Thomalla, Götz AU - Golsari, Amir AU - Alegiani, Anna AU - Beck, Christoph AU - Choe, Chi-un AU - Voget, Dieke AU - Hoppe, Julia AU - Schröder, Julian AU - Rozanski, Michal AU - Nave, Alexander H. AU - Wollboldt, Christian AU - van Sloten, Isabelle AU - Göhler, Jos AU - Herm, Juliane AU - Jungehülsing, Jan ED - Lückl, János / Collaborator AU - Kröber, Jan M. AU - Schurig, Johannes AU - Koehler, Luzie AU - Schlemm, Ludwig AU - Knops, Michael AU - Roennefarth, Maria AU - Ipsen, Nils AU - Harmel, Peter AU - Bathe-Peters, Rouven AU - Fleischmann, Robert AU - Ganeshan, Ramanan AU - Geran, Rohat AU - Hellwig, Simon AU - Schmidt, Sein AU - Tütüncü, Serdar AU - Krause, Thomas AU - Gramse, Verena AU - Röther, Joachim AU - Michels, Peter AU - Michalski, Dominik AU - Pelz, Johann AU - Schulz, Andreas AU - Hobohm, Carsten AU - Weise, Christopher AU - Weise, Gesa AU - Orthgieß, Johannes AU - Pomrehn, Katrin AU - Wegscheider, Mirko AU - Mueller, Anne K. AU - Hennerici, Michael AU - Griebe, Martin AU - Alonso, Angelika AU - Filipov, Alexandra AU - Marzina, Annika AU - Anders, Bettina AU - Bähr, Christian AU - Hoyer, Carolin AU - Schwarzbach, Christopher AU - Weber, Claudia AU - Hornberger, Eva AU - Pledl, Hans-Werner AU - Klockziem, Matti AU - Stuermlinger, Markus AU - Wittayer, Matthias AU - Wolf, Marc AU - Meyer, Nadja AU - Eisele, Philipp AU - Steinert, Susanne AU - Sauer, Tamara AU - Held, Valentin AU - Ringleb, Peter AU - Nagel, Simon AU - Veltkamp, Roland AU - Schwarting, Sönke AU - Schwarz, Alexander AU - Gumbinger, Christoph AU - Hametner, Christian AU - Amiri, Hemasse AU - Purrucker, Jan AU - Ciatipis, Mareva AU - Menn, Oliver AU - Mundiyanapurath, Sibu AU - Schieber, Simon AU - Kessler, Tobias AU - Reiff, Tilman AU - Panitz, Verena AU - Singer, Oliver AU - Foerch, Christian AU - Lauer, Arne AU - Männer, Anika AU - Seiler, Alexander AU - Guerzoglu, Damla AU - Schäfer, Jan H. AU - Filipski, Katharina AU - Lorenz, Matthias AU - Kurka, Natalia AU - Zeiner, Pia AU - Pfeilschifter, Waltraud AU - Dziewas, Rainer AU - Minnerup, Jens AU - Albiker, Christian AU - Ritter, Martin AU - Seidel, Matthias AU - Dittrich, Ralf AU - Kallmünzer, Bernd AU - Bobinger, Tobias AU - Madzar, Dominik AU - Stark, David AU - Sembill, Jochen AU - Macha, Kosmas AU - Winder, Klemens AU - Breuer, Lorenz AU - Koehrmann, Martin AU - Spruegel, Maximilian AU - Gerner, Stefan AU - Kraft, Peter AU - Mackenrodt, Daniel AU - Kleinschnitz, Christoph AU - Elhfnawy, Ahmed AU - Heinen, Florian AU - Gunreben, Ignaz AU - Poli, Sven AU - Ziemann, Ulf AU - Gaenslen, Alexandra AU - Schlak, Dennis AU - Haertig, Florian AU - Russo, Francesca AU - Richter, Hardy AU - Ebner, Matthias AU - Ribitsch, Martin AU - Wolf, Martin AU - Weimar, Christian AU - Zegarac, Vesna AU - Chen, Hsin-Chieh AU - Althaus, Katharina AU - Neugebauer, Hermann AU - Jüttler, Eric AU - Meier, Julia AU - Stösser, Sebastian AU - Puetz, Volker AU - Bodechtel, Ulf AU - Ostergaard, Leif AU - Møller, Anette AU - Damgaard, Dorte AU - Dupont, Kristina Hougaard AU - Poulsen, Marika AU - Hjort, Niels AU - de Morales, Noelia Ruiz AU - von Weitzel, Paul AU - Harbo, Thomas AU - Marstrand, Jacob AU - Hansen, Andreas AU - Christensen, Hanne AU - Aegidius, Karen AU - Jeppesen, Lise AU - Meden, Per AU - Rosenbaum, Sverre AU - Iversen, Helle AU - Hansen, Jakob AU - Michelsen, Lene AU - Truelsen, Thomas AU - Modrau, Boris AU - Vestergaard, Karsten AU - Oppel, Lorenz AU - Sygehus, Aalborg AU - Aalborg, Syd AU - Swinnen, Bart AU - Smets, Ide AU - Demeestere, Jelle AU - Dobbels, Laurens AU - Brouns, Raf AU - De Smedt, Ann AU - DeKeyser, Jacques AU - Yperzeele, Laetita AU - Van Hooff, Robbert- Jan AU - Peeters, Andre AU - Dusart, Anne AU - Etexberria, Ana AU - Hanseeuw, Bernard AU - London, Frederic AU - Leempoel, Jonathan AU - Hohenbichler, Katharina AU - Younan, Nadia AU - Maqueda, Vicky AU - Laloux, Patrice AU - De Coene, Beatrijs AU - De Maeseneire, Charlotte AU - Turine, Gaetane AU - Vandermeeren, Yves AU - De Klippel, Nina AU - Willems, Chris AU - de Hollander, Isabel AU - Soors, Peter AU - Hermans, Sylvia AU - Hemelsoet, Dimitri AU - Desfontaines, Philippe AU - Vanacker, Peter AU - Rutgers, Matthieu AU - Druart, Charlotte AU - Peeters, Dirk AU - Bruneel, Bart AU - Vancaester, Evelien AU - Vanhee, Frederik AU - Meersman, Guy AU - Bourgeois, Paul AU - Vanderdonckt, Patrick AU - Benoit, Amandine AU - Derex, Laurent AU - Mechthouff, Laura AU - Berhoune, Nadia AU - Ritzenthaler, Thomas AU - Amarenco, Pierre AU - Hobeanu, Cristina AU - Gancedo, Elena Meseguer AU - Calvet, David AU - Ladoux, Alexandre AU - Machet, Alexandre AU - Lamy, Catherine AU - Mellerio, Charles AU - Oppenheim, Catherine AU - Rodriguez-Regent, Christine AU - Bodiguel, Eric AU - Turc, Guillaume AU - Birchenall, Julia AU - Legrand, Laurence AU - Morin, Ludovic AU - Edjali-Goujon, Myriam AU - Naggara, Oliver AU - Raphaelle, Soulliard AU - Godon-Hardy, Sylvie AU - Domigo, Valérie AU - Guiraud, Vincent AU - Samson, Yves AU - Leger, Anne AU - Rosso, Charlotte AU - Baronnet-Chauvet, Flore AU - Crozier, Sophie AU - Deltour, Sandrine AU - Yger, Marion AU - Sibon, Igor AU - Renou, Pauline AU - Sagnier, Sharmilla AU - Zuber, Mathieu AU - Tamazyan, Ruben AU - Rodier, Gilles AU - Morel, Nathalie AU - Felix, Sandra AU - Vadot, Wilfried AU - Wolff, Valerie AU - Aniculaesei, Adriana AU - Yalo, Bertrand AU - Bindila, Daniela AU - Quenardelle, Veronique AU - Blanc-Lasserre, Karine AU - Landrault, Emmanuelle AU - Breynaert, Ludovic AU - Cakmak, Serkan AU - Peysson, Stéphane AU - Viguier, Alain AU - Lebely, Claire AU - Raposo, Nicolas AU - Vallet, Anne-Evelyne AU - Vallet, Pauline AU - Brugirard, Sébastian AU - Cheripelli, Bharath AU - Kalladka, Dheeraj AU - Moreton, Fiona AU - Dani, Krishna AU - Tawil, Salwa El AU - Ramachandran, Sankaranarayanan AU - Huang, Xuya AU - Warburton, Elisabeth AU - Evans, Nicholas AU - Perry, Richard AU - Patel, Bhavni AU - Cloud, Geoffrey AU - Pereira, Anthony AU - Moynihan, Barry AU - Lovelock, Caroline AU - Choy, Lillian AU - Khan, Usman AU - Roffe, Christine AU - Tyrell, Pippa AU - Smith, Craig AU - Dixit, Anand AU - Louw, Stephen AU - Broughton, David AU - Shetty, Ashit AU - Appleton, Jason AU - Sprigg, Nikola AU - Acosta, Boris Raul AU - van Eendenburg, Cecile AU - Leal, Joaquin Serena AU - Mar Castellanos Rodrigo, Maria del AU - Izaga, Mikel Terceno AU - Guillamon, Olga Belchí AU - Arenillas, Juan AU - Calleja, Ana AU - Cortijo, Elisa AU - Mulero, Patricia AU - de la Ossa, Natalia Pérez AU - Garrido, Alicia AU - Martinez, Alicia AU - Esperón, Carlos García AU - Guerrero, Cristina AU - Carrera, David AU - Vilas, Dolores AU - Lopez-cancio, Elena AU - Palomeras, Ernest AU - Lucente, Giuseppe AU - Gomis, Meritxell AU - Isern, Irina AU - Becerra, Juan L. AU - Vicente, Jose Hervas AU - Sánchez, Josep AU - Dorado, Laura AU - Grau, Laia AU - Ispierto, Lourdes AU - Prats, Luis AU - Almendrote, Miriam AU - Hernández, María AU - Jimenez, Marta AU - Sánchez, Manuel Lozano AU - Torne, Monica Millán AU - Presas, Silvia AU - Ustrell, Xavier AU - Pellisé, Anna AU - Navalpotro, Irene AU - Luna, Alain AU - Schonewille, Wouter AU - Nederkoorn, Paul AU - Majoie, Charles AU - van den Berg, Lucie AU - van den Berg, Sophie AU - Zonneveld, Thomas AU - Remmers, Michel AU - Fazekas, Franz AU - Pichler, Alexander AU - Fandler, Simon AU - Gattringer, Thomas AU - Mutzenbach, Johannes AU - Weber, Jörg AU - Höfner, Elmar AU - Kohlfürst, Heinz AU - Weinstich, Karin AU - Kellert, Lars AU - Bayer-Karpinska, Anna AU - Opherk, Christian AU - Wollenweber, Frank AU - Klein, Matthias AU - Neumann- Haefelin, Tobias AU - Pierskalla, Alexandra AU - Harloff, Andreas AU - Bardutzky, Jürgen AU - Buggle, Florian AU - von Schrader, Jörg AU - Kollmar, Rainer AU - Schill, Josef AU - Löbbe, Anna-Mareike AU - Moulin, Thierry AU - Bouamra, Benjamin AU - Bonnet, Louise AU - Touzé, Emmanuel AU - Bonnet, Anne-Laure AU - Touze, Emmanuel AU - Cogez, Julien AU - Li, Lin AU - Guettier, Sophie AU - Kar, Arindam AU - Sivagnanaratham, Aravinth AU - Geraghty, Olivia AU - Bojaryn, Urszula AU - Nallasivan, Arumugam AU - Gonzales, Miguel Blanco AU - Rodríguez-Yáñez, Manuel AU - Tembl, Jose AU - Gorriz, David AU - Oberndorfer, Stefan AU - Prohaska, Elisabeth TI - Quantitative Signal Intensity in Fluid-Attenuated Inversion Recovery and Treatment Effect in the WAKE-UP Trial JF - STROKE J2 - STROKE VL - 51 PY - 2020 IS - 1 SP - 209 EP - 215 PG - 7 SN - 0039-2499 DO - 10.1161/STROKEAHA.119.027390 UR - https://m2.mtmt.hu/api/publication/31138704 ID - 31138704 LA - English DB - MTMT ER - TY - CONF AU - Emri, Miklós AU - Aranyi, Sándor Csaba AU - Fajtai, Dániel AU - Tóth, Márton AU - Lückl, János AU - Vajda, Zsolt AU - Repa, Imre AU - Tóth, Zoltán TI - MULTIMODÁLIS VIZUALIZÁCIÓS ÉS STATISZTIKAI MÓDSZEREK FEJLESZTÉSE AZ EPILEPSZIA DIAGNOSZTIKA SZÁMÁRA T2 - MONT XXI. kongresszus 2019 PY - 2019 SP - 72 EP - 72 PG - 1 UR - https://m2.mtmt.hu/api/publication/30747579 ID - 30747579 LA - Hungarian DB - MTMT ER - TY - CONF AU - Tóth, Zoltán AU - Fekésházy, Attila AU - Mendly, József AU - Emri, Miklós AU - Fajtai, Dániel AU - Lukács, Gábor AU - Lückl, János AU - Bajzik, Gábor AU - Hadjiev, Janaki AU - Repa, Imre AU - Kovács, Árpád TI - Neurológiai indikációjú DOPA PET/MR vizsgálatokkal szerzett kezdeti tapasztalatok T2 - Magyar Neurológiai Társaság XXVI. Kongresszusa és Továbbképző Kurzusa PY - 2018 SP - 44 EP - 45 PG - 2 UR - https://m2.mtmt.hu/api/publication/30757620 ID - 30757620 LA - Hungarian DB - MTMT ER -