@article{MTMT:2989762,
	title = {Restraint stress-induced morphological changes at the blood-brain barrier in adult rats},
	url = {https://m2.mtmt.hu/api/publication/2989762},
	author = {Sántha, Petra and Veszelka, Szilvia and Hoyk, Zsófia and Mészáros, Mária and Walter, Fruzsina and Tóth, Andrea and Kiss, Lóránd and Kincses, András and Oláh, Zita and Seprényi, György and Rákhely, Gábor and Dér, András and Pákáski, Magdolna and Kálmán, János and Kittel, Ágnes and Deli, Mária Anna},
	doi = {10.3389/fnmol.2015.00088},
	journal-iso = {FRONT MOL NEUROSCI},
	journal = {FRONTIERS IN MOLECULAR NEUROSCIENCE},
	volume = {8},
	unique-id = {2989762},
	issn = {1662-5099},
	year = {2016},
	eissn = {1662-5099},
	orcid-numbers = {Walter, Fruzsina/0000-0001-8145-2823; Oláh, Zita/0000-0002-6372-532X; Rákhely, Gábor/0000-0003-2557-3641; Pákáski, Magdolna/0000-0001-8067-5435; Kálmán, János/0000-0001-5319-5639; Deli, Mária Anna/0000-0001-6084-6524}
}

@article{MTMT:2920970,
	title = {Cultured cells of the blood-brain barrier from apolipoprotein B-100 transgenic mice: effects of oxidized low-density lipoprotein treatment},
	url = {https://m2.mtmt.hu/api/publication/2920970},
	author = {Lénárt, Nikolett and Walter, Fruzsina and Bocsik, Alexandra and Sántha, Petra and Tóth, Erzsébet Melinda and Harazin, András and Tóth, Andrea and Vizler, Csaba and Török, Zsolt and Pilbat, Ana Maria and Vigh, László and Puskás, László and Sántha, Miklós and Deli, Mária Anna},
	doi = {10.1186/s12987-015-0013-y},
	journal-iso = {FLUIDS BARRIERS CNS},
	journal = {FLUIDS AND BARRIERS OF THE CNS},
	volume = {12},
	unique-id = {2920970},
	issn = {2045-8118},
	year = {2015},
	eissn = {2045-8118},
	orcid-numbers = {Lénárt, Nikolett/0000-0002-7456-949X; Walter, Fruzsina/0000-0001-8145-2823; Harazin, András/0000-0002-0904-5606; Deli, Mária Anna/0000-0001-6084-6524}
}

@mastersthesis{MTMT:2781263,
	title = {Stress-induced changes in gene transcriptions and translations related to Alzheimer’s disease},
	url = {https://m2.mtmt.hu/api/publication/2781263},
	author = {Sántha, Petra},
	doi = {10.14232/phd.2358},
	publisher = {SZTE},
	unique-id = {2781263},
	year = {2014}
}

@article{MTMT:2773366,
	title = {Low dose cranial irradiation-induced cerebrovascular damage is reversible in mice},
	url = {https://m2.mtmt.hu/api/publication/2773366},
	author = {Sándor, Nikolett and Walter, Fruzsina and Bocsik, Alexandra and Sántha, Petra and Schilling-Tóth, Boglárka and Léner, Violetta and Varga, Zoltán and Kahán, Zsuzsanna and Deli, Mária Anna and Sáfrány, Géza and Hegyesi, Hargita},
	doi = {10.1371/journal.pone.0112397},
	journal-iso = {PLOS ONE},
	journal = {PLOS ONE},
	volume = {9},
	unique-id = {2773366},
	issn = {1932-6203},
	year = {2014},
	eissn = {1932-6203},
	orcid-numbers = {Walter, Fruzsina/0000-0001-8145-2823; Schilling-Tóth, Boglárka/0000-0003-0548-1416; Varga, Zoltán/0000-0001-8537-6282; Kahán, Zsuzsanna/0000-0002-5021-8775; Deli, Mária Anna/0000-0001-6084-6524; Hegyesi, Hargita/0000-0002-8800-5169}
}

@article{MTMT:2707330,
	title = {Edaravone protects against methylglyoxal-induced barrier damage in human brain endothelial cells},
	url = {https://m2.mtmt.hu/api/publication/2707330},
	author = {Tóth, Andrea and Walter, Fruzsina and Bocsik, Alexandra and Sántha, Petra and Veszelka, Szilvia and Nagy, Lajos István and Puskás, László and Couraud, PO and Takata, F and Dohgu, S and Kataoka, Y and Deli, Mária Anna},
	doi = {10.1371/journal.pone.0100152},
	journal-iso = {PLOS ONE},
	journal = {PLOS ONE},
	volume = {9},
	unique-id = {2707330},
	issn = {1932-6203},
	abstract = {BACKGROUND:
		
		Elevated level of reactive carbonyl species, such as methylglyoxal, triggers carbonyl stress and activates a series of inflammatory responses leading to accelerated vascular damage. Edaravone is the active substance of a Japanese medicine, which aids neurological recovery following acute brain ischemia and subsequent cerebral infarction. Our aim was to test whether edaravone can exert a protective effect on the barrier properties of human brain endothelial cells (hCMEC/D3 cell line) treated with methylglyoxal.
		METHODOLOGY:
		
		Cell viability was monitored in real-time by impedance-based cell electronic sensing. The barrier function of the monolayer was characterized by measurement of resistance and flux of permeability markers, and visualized by immunohistochemistry for claudin-5 and β-catenin. Cell morphology was also examined by holographic phase imaging.
		PRINCIPAL FINDINGS:
		
		Methylglyoxal exerted a time- and dose-dependent toxicity on cultured human brain endothelial cells: a concentration of 600 µM resulted in about 50% toxicity, significantly reduced the integrity and increased the permeability of the barrier. The cell morphology also changed dramatically: the area of cells decreased, their optical height significantly increased. Edaravone (3 mM) provided a complete protection against the toxic effect of methylglyoxal. Co-administration of edaravone restored cell viability, barrier integrity and functions of brain endothelial cells. Similar protection was obtained by the well-known antiglycating molecule, aminoguanidine, our reference compound.
		CONCLUSION:
		
		These results indicate for the first time that edaravone is protective in carbonyl stress induced barrier damage. Our data may contribute to the development of compounds to treat brain endothelial dysfunction in carbonyl stress related diseases.},
	year = {2014},
	eissn = {1932-6203},
	orcid-numbers = {Walter, Fruzsina/0000-0001-8145-2823; Deli, Mária Anna/0000-0001-6084-6524}
}

@CONFERENCE{MTMT:2701829,
	title = {Stressz hatása a vér-agy-gátra: mikroszkópos vizsgálatok patkány agymetszeteken = [Effects of stress on the blood-brain-barrier: microscopic studies on rat brain sections]},
	url = {https://m2.mtmt.hu/api/publication/2701829},
	author = {Sántha, Petra and Veszelka, Szilvia and Kiss, Lóránd and Walter, Fruzsina and Oláh, Zita and Tóth, Andrea and Bocsik, Alexandra and Pákáski, Magdolna and Kálmán, János and Kittel, Ágnes and Deli, Mária},
	booktitle = {14. Kolozsvári Biológus Napok : Kolozsvár, 2013. április 12-14. : kivonatfüzet = [14th Biology Days : Cluj-Napoca, 12-14 April 2013 : abstracts]},
	unique-id = {2701829},
	year = {2013},
	pages = {54-54},
	orcid-numbers = {Oláh, Zita/0000-0002-6372-532X; Pákáski, Magdolna/0000-0001-8067-5435; Kálmán, János/0000-0001-5319-5639}
}

@CONFERENCE{MTMT:2701821,
	title = {Immobilizációs stressz hatása a β-aktin citoszkeletonra vad típusú és apoB transzgénikus egér agyban = [The effect of immobilization stress on the β-actin cytoskeleton in wild type and apoB transgenic mice brain]},
	url = {https://m2.mtmt.hu/api/publication/2701821},
	author = {Fodor, Eszter and Pákáski, Magdolna and Sántha, Petra and Sántha, Miklós and Janka, Zoltán and Kálmán, János},
	booktitle = {14. Kolozsvári Biológus Napok : Kolozsvár, 2013. április 12-14. : kivonatfüzet = [14th Biology Days : Cluj-Napoca, 12-14 April 2013 : abstracts]},
	unique-id = {2701821},
	year = {2013},
	pages = {26-26},
	orcid-numbers = {Pákáski, Magdolna/0000-0001-8067-5435; Kálmán, János/0000-0001-5319-5639}
}

@article{MTMT:2500898,
	title = {Életünk a stressz árnyékában},
	url = {https://m2.mtmt.hu/api/publication/2500898},
	author = {Sántha, Petra},
	journal-iso = {ÉLET ÉS TUDOMÁNY},
	journal = {ÉLET ÉS TUDOMÁNY},
	volume = {47},
	unique-id = {2500898},
	issn = {0013-6077},
	year = {2013},
	pages = {1488-1489}
}

@article{MTMT:2437204,
	title = {Cytoskeletal Protein Translation and Expression in the Rat Brain Are Stressor-Dependent and Region-Specific},
	url = {https://m2.mtmt.hu/api/publication/2437204},
	author = {Sántha, Petra and Pákáski, Magdolna and Fodor, Eszter and Fazekas, OC and Kálmán, Sára and Kálmán, János (ifj.) and Janka, Zoltán and Szabó, Gyula and Kálmán, János},
	doi = {10.1371/journal.pone.0073504},
	journal-iso = {PLOS ONE},
	journal = {PLOS ONE},
	volume = {8},
	unique-id = {2437204},
	issn = {1932-6203},
	abstract = {Stress is an integral component of life that can sometimes cause a critical overload, depending on the qualitative and quantitative natures of the stressors. The involvement of actin, the predominant component of dendritic integrity, is a plausible candidate factor in stress-induced neuronal cytoskeletal changes. The major aim of this study was to compare the effects of three different stress conditions on the transcription and translation of actin-related cytoskeletal genes in the rat brain. Male Wistar rats were exposed to one or other of the frequently used models of physical stress, i.e. electric foot shock stress (EFSS), forced swimming stress (FSS), or psychosocial stress (PSS) for periods of 3, 7, 14, or 21 days. The relative mRNA and protein expressions of beta-actin, cofilin and mitogen-activated protein kinase 1 (MAPK-1) were determined by qRT- PCR and western blotting from hippocampus and frontal cortex samples. Stressor-specific alterations in both beta-actin and cofilin expression levels were seen after stress. These alterations were most pronounced in response to EFSS, and exhibited a U-shaped time course. FSS led to a significant beta-actin mRNA expression elevation in the hippocampus and the frontal cortex after 3 and 7 days, respectively, without any subsequent change. PSS did not cause any change in beta-actin or cofilin mRNA or protein expression in the examined brain regions. EFSS, FSS and PSS had no effect on the expression of MAPK-1 mRNA at any tested time point. These findings indicate a very delicate, stress type-dependent regulation of neuronal cytoskeletal components in the rat hippocampus and frontal cortex.},
	year = {2013},
	eissn = {1932-6203},
	orcid-numbers = {Pákáski, Magdolna/0000-0001-8067-5435; Szabó, Gyula/0000-0002-3409-5357; Kálmán, János/0000-0001-5319-5639}
}

@article{MTMT:2701705,
	title = {Immobilizációs stressz hatása a β-aktin citoszkeletonra apoB transzgénikus egér agyban},
	url = {https://m2.mtmt.hu/api/publication/2701705},
	author = {Fodor, Eszter Klára and Sántha, Petra and Oláh, Zita and Sántha, Miklós and Pákáski, Magdolna and Janka, Zoltán and Kálmán, János},
	journal-iso = {NEUROPSYCHOPHARM HUNG},
	journal = {NEUROPSYCHOPHARMACOLOGIA HUNGARICA},
	volume = {14},
	unique-id = {2701705},
	issn = {1419-8711},
	year = {2012},
	pages = {21-21},
	orcid-numbers = {Oláh, Zita/0000-0002-6372-532X; Pákáski, Magdolna/0000-0001-8067-5435; Kálmán, János/0000-0001-5319-5639}
}