TY - JOUR AU - Mohos, Gábor AU - Kocsis, Ádám László AU - Erős, Gábor AU - Korponyai, Csilla AU - Varga, Ákos AU - Bende, Balázs AU - Varga, János TI - Reconstruction of Alar-Perialar Defects with a Combined Subcutaneous and Cutaneous Pedicled Rotation-Advancement Nasolabial Flap JF - JOURNAL OF INVESTIGATIVE SURGERY J2 - J INVEST SURG VL - 33 PY - 2020 IS - 7 SP - 666 EP - 672 PG - 7 SN - 0894-1939 DO - 10.1080/08941939.2018.1538397 UR - https://m2.mtmt.hu/api/publication/30634855 ID - 30634855 AB - During the reconstruction of alar defects involving the upper lip, reconstructive surgeons face the need for various thicknesses of tissues crucial to preserving the facial sulcus which is important for a cosmetically acceptable result. Our aim was to reconstruct the deep perialar and thinner lateral nasal alar defect in a single step procedure with a suitable flap which is reliable, has appropriate blood supply and provides an esthetically good result.Extended alar defect was reconstructed with a combined flap in 10 cases. During the procedure, a subcutaneous pedicle was created and the proximal part of the flap was rotated into the defect as a rotational flap. The procedure and the follow-up have been photo-documented in all cases. Furthermore, the perfusion of the flaps was monitored by means of laser Doppler flowmetry. Postoperative complications were evaluated with a semi-quantitative score and the patients completed a patient satisfaction questionnaire, too.An optimal esthetic result was obtained in all cases after the operation. The lateral nasal alar part of the defect was reconstructed with the thinner proximal part of the flap while the deeper perialar region involving the upper lip was covered with the thicker distal part. The flaps have shown sufficient blood flow after the operation. There was no significant pin cushioning or "trap-door" effect in any case. Mild erythema and edema was found in few cases. The patients were satisfied with the cosmetic result of the intervention.The flap is suitable for the reconstruction of alar defects involving the perialar region. It has the advantage of covering the deeper perialar and the thinner alar defects, whilst eliminating the pin cushioning effect of the conventional subcutaneous island pedicle flaps. LA - English DB - MTMT ER - TY - JOUR AU - Szél, Edit AU - Danis, Judit AU - Sőrés, Evelin AU - Tóth, Dániel AU - Korponyai, Csilla AU - Degovics, Döníz AU - Prorok, János AU - Acsai, Károly AU - Dikstein, Shabtay AU - Kemény, Lajos AU - Erős, Gábor TI - Protective effects of glycerol and xylitol in keratinocytes exposed to hyperosmotic stress JF - CLINICAL COSMETIC AND INVESTIGATIONAL DERMATOLOGY J2 - CLIN COSMET INV DERM VL - 12 PY - 2019 SP - 323 EP - 331 PG - 9 SN - 1178-7015 DO - 10.2147/CCID.S197946 UR - https://m2.mtmt.hu/api/publication/30680175 ID - 30680175 LA - English DB - MTMT ER - TY - THES AU - Korponyai, Csilla TI - The role of polyols and amino acids in the maintenance of homeostasis in the skin PB - Szegedi Tudományegyetem (SZTE) PY - 2017 SP - 50 DO - 10.14232/phd.4015 UR - https://m2.mtmt.hu/api/publication/3346655 ID - 3346655 LA - English DB - MTMT ER - TY - JOUR AU - Korponyai, Csilla AU - Szél, Edit AU - Behany, Z AU - Varga, Erika AU - Mohos, Gábor AU - Dura, A AU - Dikstein, S AU - Kemény, Lajos AU - Erős, Gábor TI - The effects of locally applied glycerol and xylitol on the hydration, barrier function and morphological parameters of the skin JF - ACTA DERMATO-VENEREOLOGICA J2 - ACTA DERM-VENEREOL VL - 97 PY - 2017 IS - 2 SP - 182 EP - 187 PG - 6 SN - 0001-5555 DO - 10.2340/00015555-2493 UR - https://m2.mtmt.hu/api/publication/3097079 ID - 3097079 N1 - Megjegyzés-26581988 Megjegyzés-27128742 OA gold Department of Dermatology and Allergology, University of Szeged, Szeged, Hungary Central Pharmacy, University of Szeged, Szeged, Hungary Unit of Cell Pharmacology, School of Pharmacy, The Hebrew University, Jerusalem, Israel MTA-SZTE Dermatological Research Group, Szeged, Hungary Department of Pathology, University of Szeged, Szeged, Hungary Cited By :8 Export Date: 28 August 2019 CODEN: ADVEA Correspondence Address: Korponyai, C.; Department of Dermatology and Allergology, Faculty of Medicine, University of Szeged, Korányi fasor 6., Hungary; email: csillakorponyai81@gmail.com Chemicals/CAS: glycerol, 56-81-5; interstitial collagenase, 9001-12-1; xylitol, 87-99-0; filaggrin; Gels; Glycerol; Intermediate Filament Proteins; Matrix Metalloproteinase 1; Xylitol Department of Dermatology and Allergology, University of Szeged, Szeged, Hungary Central Pharmacy, University of Szeged, Szeged, Hungary Unit of Cell Pharmacology, School of Pharmacy, The Hebrew University, Jerusalem, Israel MTA-SZTE Dermatological Research Group, Szeged, Hungary Department of Pathology, University of Szeged, Szeged, Hungary Cited By :14 Export Date: 29 August 2020 CODEN: ADVEA Correspondence Address: Korponyai, C.; Department of Dermatology and Allergology, Faculty of Medicine, University of Szeged, Korányi fasor 6., Hungary; email: csillakorponyai81@gmail.com Chemicals/CAS: glycerol, 56-81-5; interstitial collagenase, 9001-12-1; xylitol, 87-99-0; filaggrin; Gels; Glycerol; Intermediate Filament Proteins; Matrix Metalloproteinase 1; Xylitol Department of Dermatology and Allergology, University of Szeged, Szeged, Hungary Central Pharmacy, University of Szeged, Szeged, Hungary Unit of Cell Pharmacology, School of Pharmacy, The Hebrew University, Jerusalem, Israel MTA-SZTE Dermatological Research Group, Szeged, Hungary Department of Pathology, University of Szeged, Szeged, Hungary Cited By :18 Export Date: 12 March 2021 CODEN: ADVEA Correspondence Address: Korponyai, C.; Department of Dermatology and Allergology, Korányi fasor 6., Hungary; email: csillakorponyai81@gmail.com Chemicals/CAS: glycerol, 56-81-5; interstitial collagenase, 9001-12-1; xylitol, 87-99-0; filaggrin; Gels; Glycerol; Intermediate Filament Proteins; Matrix Metalloproteinase 1; Xylitol AB - Glycerol and xylitol hydrate the skin and improve its barrier function over a short period. We studied the effects of glycerol and xylitol on the physiological properties and morphology of the skin after longer-term application. Twelve volunteers with dry skin were examined. Three areas on the arms were determined. Area 1 served as untreated control. The vehicle was applied to area 2, while area 3 was treated twice daily with a formulation containing glycerol (5%) and xylitol (5%) for 14 days. Transepidermal water loss (TEWL), hydration and biomechanical properties of the skin were monitored. Biopsies were taken for routine histology and immunohistochemistry for filaggrin and matrix metalloproteinase-1 (MMP-1). The polyols increased the skin hydration and protein quantity of filaggrin, elevated the interdigitaion index, decreased the TEWL and improved the biomechanical properties of the skin, but did not change the protein expression of MMP-1. A combination of glycerol and xylitol can be useful additional therapy for dry skin. LA - English DB - MTMT ER - TY - JOUR AU - Meszes, Angéla AU - Korponyai, Csilla AU - Orvos, Hajnalka AU - Csoma, Zsanett TI - Transient Zebra-like Hyperpigmentation in a Healthy Newborn JF - INDIAN JOURNAL OF PEDIATRICS J2 - INDIAN J PEDIATR VL - 83 PY - 2016 IS - 7 SP - 758 EP - 759 PG - 2 SN - 0019-5456 DO - 10.1007/s12098-015-1937-6 UR - https://m2.mtmt.hu/api/publication/2981287 ID - 2981287 LA - English DB - MTMT ER - TY - JOUR AU - Szél, Edit AU - Polyánka, Hilda AU - Szabó, Kornélia Ágnes AU - Hartmann, Petra AU - Degovics, Döníz AU - Balázs, Boglárka AU - Németh, István Balázs AU - Korponyai, Csilla AU - Csányi, Erzsébet AU - Kaszaki, József AU - Dikstein, S AU - Nagy, Katalin AU - Kemény, Lajos AU - Erős, Gábor TI - Anti-irritant and anti-inflammatory effects of glycerol and xylitol in sodium lauryl sulphate-induced acute irritation JF - JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY J2 - J EUR ACAD DERMATOL VL - 29 PY - 2015 IS - 12 SP - 2333 EP - 2341 PG - 9 SN - 0926-9959 DO - 10.1111/jdv.13225 UR - https://m2.mtmt.hu/api/publication/2942019 ID - 2942019 LA - English DB - MTMT ER - TY - JOUR AU - Erős, Gábor AU - Korponyai, Csilla AU - Szabó, Kornélia Ágnes AU - Behány, Zoltán AU - Szél, Edit AU - Kemény, Lajos TI - A glicerolt és xilitolt tartalmazó Xylinep® gél antibakteriális és bőrhidratáló hatásai. Antibacterial and skin hydrating effects Xylinep® gel containing glycerol- and xylitol TS - Antibacterial and skin hydrating effects Xylinep® gel containing glycerol- and xylitol JF - BŐRGYÓGYÁSZATI ÉS VENEROLÓGIAI SZEMLE J2 - BVSZ VL - 90 PY - 2014 IS - 4 SP - 152 EP - 155 PG - 4 SN - 0006-7768 DO - 10.7188/bvsz.2014.90.4.4 UR - https://m2.mtmt.hu/api/publication/2814347 ID - 2814347 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Korponyai, Csilla AU - Szél, Edit AU - Behány, Z AU - Mohos, Gábor AU - Dikstein, S AU - Nagy, Katalin AU - Kemény, Lajos AU - Erős, Gábor TI - A lokálisan alkalmazott glicerol, xilitol és metionin hatásai a bőr hidratációjára, barrier funkciójára és morfológiájára JF - BŐRGYÓGYÁSZATI ÉS VENEROLÓGIAI SZEMLE J2 - BVSZ VL - 90 PY - 2014 IS - 6 SP - 275 PG - 1 SN - 0006-7768 UR - https://m2.mtmt.hu/api/publication/2790928 ID - 2790928 N1 - A folyóirat teljes száma: http://www.derma.hu/upload/dermatologia/magazine/bvsz_2014_6_3_43.pdf LA - Hungarian DB - MTMT ER - TY - JOUR AU - Szél, Edit AU - Erős, Gábor AU - Hartmann, Petra AU - Németh, István Balázs AU - Degovics, Döníz AU - Korponyai, Csilla AU - Kaszaki, József AU - Polyánka, Hilda AU - Szabó, Kornélia Ágnes AU - Dikstein, S AU - Nagy, Katalin AU - Kemény, Lajos TI - Poliolok antiirritáns és gyulladáscsökkentő hatása irritatív kontakt dermatitiszben JF - BŐRGYÓGYÁSZATI ÉS VENEROLÓGIAI SZEMLE J2 - BVSZ VL - 90 PY - 2014 IS - 6 SP - 261 PG - 1 SN - 0006-7768 UR - https://m2.mtmt.hu/api/publication/2790740 ID - 2790740 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Korponyai, Csilla AU - Meszes, Angéla AU - Kemény, Lajos AU - Gyurkovits, Zita AU - Bakki, Judit AU - Orvos, Hajnalka AU - Csoma, Zsanett TI - Tranziens zebra szerű hyperpigmentáció újszülöttkorban. JF - GYERMEKGYÓGYÁSZAT J2 - GYERMEKGYÓGYÁSZAT VL - 65 PY - 2014 IS - 3 SP - 189 EP - 189 PG - 1 SN - 0017-5900 UR - https://m2.mtmt.hu/api/publication/2708576 ID - 2708576 LA - Hungarian DB - MTMT ER -