@article{MTMT:34797501,
	title = {Monogénesen öröklődő és szerzett autoinflammatoricus betegségek},
	url = {https://m2.mtmt.hu/api/publication/34797501},
	author = {Szekanecz, Zoltán and Szamosi, Szilvia and Benkő, Szilvia and Szűcs, Gabriella},
	journal-iso = {ORV HETIL},
	journal = {ORVOSI HETILAP},
	volume = {165},
	unique-id = {34797501},
	issn = {0030-6002},
	year = {2024},
	eissn = {1788-6120},
	pages = {683-697}
}

@article{MTMT:34745209,
	title = {Natural Autoantibodies in Biologic-Treated Rheumatoid Arthritis and Ankylosing Spondylitis Patients: Associations with Vascular Pathophysiology},
	url = {https://m2.mtmt.hu/api/publication/34745209},
	author = {Simon, Diána and Kacsándi, Dorottya and Karancsiné Pusztai, Anita and Soós, Boglárka and Végh, Edit and Kerekes, György and Czókolyová, Monika and Szamosi, Szilvia and Szűcs, Gabriella and Prohászka, Zoltán and Németh, Péter and Berki, Tímea and Szekanecz, Zoltán},
	doi = {10.3390/ijms25063429},
	journal-iso = {INT J MOL SCI},
	journal = {INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES},
	volume = {25},
	unique-id = {34745209},
	issn = {1661-6596},
	abstract = {Cardiovascular (CV) morbidity and mortality have been associated with rheumatoid arthritis (RA) and ankylosing spondylitis (AS). Natural autoantibodies (nAAb) are involved in innate immunity, as well as autoimmunity, inflammation, and atherosclerosis. There have not been any studies assessing the effects of biologics on nAAbs in RA and AS, also in relation to vascular pathophysiology. Fifty-three anti-TNF-treated RA and AS patients were included in a 12-month follow-up study. Anti-citrate synthase (CS) and anti-topoisomerase I fragment 4 (TOPO-F4) IgM and IgG levels were determined by ELISA. Ultrasonography was performed to assess brachial artery flow-mediated vasodilation (FMD), common carotid intima-media thickness (ccIMT), and arterial pulse-wave velocity (PWV). Other variables were also evaluated at baseline and 6 and 12 months after treatment initiation. Anti-TNF therapy improved FMD in RA and PWV in AS and stabilized ccIMT. TNF inhibition increased anti-CS IgM and IgG, and possibly also anti-TOPO-F4 IgG levels. Various correlation analyses revealed that nAAbs might be independently involved in autoimmunity as well as changes in inflammation and vascular pathology over time in biologic-treated patients (p < 0.05). We also found associations between anti-TOPO-F4 IgG and anti-Hsp60 IgG (p < 0.05). Baseline nAAb levels or nAAb level changes might determine changes in CRP, disease activity, FMD, PWV, and ccIMT over time (p < 0.05). The interplay between arthritis and inflammatory atherosclerosis, as well as the effects of anti-TNF biologics on these pathologies, might independently involve nAAbs.},
	year = {2024},
	eissn = {1422-0067},
	orcid-numbers = {Prohászka, Zoltán/0000-0003-1761-7982; Berki, Tímea/0000-0002-0134-8127}
}

@article{MTMT:34482910,
	title = {A novel way to evaluate autoantibody interference in samples with mixed antinuclear antibody patterns in the HEp-2 cell based indirect immunofluorescence assay and comparison of conventional microscopic and computer-aided pattern recognition},
	url = {https://m2.mtmt.hu/api/publication/34482910},
	author = {Nagy, Gábor and Földesi, Róza and Csípő, István and Tarr, Tünde and Szűcs, Gabriella and Szántó, Antónia and Bubán, Tamás and Szekanecz, Zoltán and Papp, Mária and Kappelmayer, János and Antal-Szalmás, Péter},
	doi = {10.1016/j.cca.2023.117747},
	journal-iso = {CLIN CHIM ACTA},
	journal = {CLINICA CHIMICA ACTA},
	volume = {553},
	unique-id = {34482910},
	issn = {0009-8981},
	year = {2024},
	eissn = {1873-3492},
	pages = {117747},
	orcid-numbers = {Nagy, Gábor/0000-0002-2943-2750; Papp, Mária/0000-0003-3662-4010}
}

@article{MTMT:34391704,
	title = {Does the impact of COVID-19 on patients with systemic sclerosis change over time?},
	url = {https://m2.mtmt.hu/api/publication/34391704},
	author = {Deibel, Elisabeth and Carreira, Patricia E. and Vonk, Madelon and del, Papa Nicoletta and Becvár, Radim and Guillén-Del-Castillo, Alfredo and Campochiaro, Corrado and Poormoghim, Hadi and Liem, Sophie and Lazzaroni, Maria-Grazia and Giollo, Alessandro and Mekinian, Arsene and de Vries-Bouwstra, Jeska and De Santis, Maria and Balbir-Gurman, Alexandra and Mihai, Carina and De Luca, Giacomo and Moiseev, Sergey and Zanatta, Elisabetta and Foti, Rosario and Rednic, Simona and Denton, Christopher and Cutolo, Maurizio and Belloli, Laura and Airo, Paolo and Garzanova, Liudmila and Moroncini, Gianluca and Inanc, Murat and Panopoulos, Stylianos and Tandaipan, Jose-Luis and Chatelus, Emmanuel and Rosato, Edoardo and Kuwana, Masataka and Yavuz, Sule and Alegre-Sancho, Juan J. and Smith, Vanessa and Szűcs, Gabriella and Henes, Joerg and Rodríguez-Pintó, Ignasi and Atzeni, Fabiola and Spierings, Julia and Truchetet, Marie-Elise and Milchert, Marcin and Brito, de Araujo Daniel and Riemekasten, Gabriela and Bernardino, Vera and Martin, Thierry and del, Galdo Francesco and Vacca, Alessandra and Mendoza, Fabian and Midtvedt, Øyvind and Murdaca, Giuseppe and Santiago, Tania and Codullo, Veronica and Cacciapaglia, Fabio and Walker, Ulrich and Brunborg, Cathrine and Tirelli, Francesca and Allanore, Yannick and Furst, Daniel E. and Matucci, Marco and Gabrielli, Armando and Distler, Oliver and Hoffmann-Vold, Anna-Maria},
	doi = {10.1002/acr.25226},
	journal-iso = {ARTHRIT CARE RES},
	journal = {ARTHRITIS CARE & RESEARCH},
	volume = {76},
	unique-id = {34391704},
	issn = {2151-464X},
	year = {2024},
	eissn = {2151-4658},
	pages = {88-97}
}

@article{MTMT:34391645,
	title = {Should we use nintedanib as early therapy in patients with SSc-ILD?},
	url = {https://m2.mtmt.hu/api/publication/34391645},
	author = {Zanatta, Elisabetta and Moccaldi, Beatrice and Szűcs, Gabriella and Spagnolo, Paolo},
	doi = {10.1016/j.autrev.2023.103463},
	journal-iso = {AUTOIMMUN REV},
	journal = {AUTOIMMUNITY REVIEWS},
	unique-id = {34391645},
	issn = {1568-9972},
	year = {2024},
	eissn = {1873-0183}
}

@article{MTMT:34775337,
	title = {AB0237 EFFECTS OF ONE-YEAR TOFACITINIB THERAPY ON ANGIOGENIC BIOMARKERS IN RHEUMATOID ARTHRITIS},
	url = {https://m2.mtmt.hu/api/publication/34775337},
	author = {Kerekes, György and Bodoki, Levente and Hamar, Attila and Karancsiné Pusztai, Anita and Tajti, Gábor and Katkó, Mónika and Végh, Edit and Pethő, Zsófia and Bodnár, Nóra and Horváth, Ágnes and Soós, B. and Szamosi, Szilvia and Hascsi, Z. and Harangi, Mariann and Panyi, György and Szűcs, Gabriella and Szekanecz, Zoltán},
	doi = {10.1136/annrheumdis-2023-eular.2331},
	journal-iso = {ANN RHEUM DIS},
	journal = {ANNALS OF THE RHEUMATIC DISEASES},
	volume = {82},
	unique-id = {34775337},
	issn = {0003-4967},
	year = {2023},
	eissn = {1468-2060},
	pages = {1303-1303},
	orcid-numbers = {Panyi, György/0000-0001-6227-3301}
}

@article{MTMT:34391690,
	title = {Sarilumab for Relapse of Polymyalgia Rheumatica during Glucocorticoid Taper},
	url = {https://m2.mtmt.hu/api/publication/34391690},
	author = {Spiera, Robert F. and Unizony, Sebastian and Warrington, Kenneth J. and Sloane, Jennifer and Giannelou, Angeliki and Nivens, Michael C. and Akinlade, Bolanle and Wong, Wanling and Bhore, Rafia and Lin, Yong and Buttgereit, Frank and Devauchelle-Pensec, Valerie and Rubbert-Roth, Andrea and Yancopoulos, George D. and Marrache, Frederic and Patel, Naimish and Dasgupta, Bhaskar},
	doi = {10.1056/NEJMoa2303452},
	journal-iso = {NEW ENGL J MED},
	journal = {NEW ENGLAND JOURNAL OF MEDICINE},
	volume = {389},
	unique-id = {34391690},
	issn = {0028-4793},
	year = {2023},
	eissn = {1533-4406},
	pages = {1263-1272},
	orcid-numbers = {Spiera, Robert F./0000-0003-2911-6800; Warrington, Kenneth J./0000-0001-7708-2487; Rubbert-Roth, Andrea/0000-0002-9016-2833}
}

@article{MTMT:34250233,
	title = {Effectiveness and waning of protection with the BNT162b2 vaccine against the SARS-CoV-2 Delta variant in immunocompromised individuals},
	url = {https://m2.mtmt.hu/api/publication/34250233},
	author = {Szekanecz, Zoltán and Vokó, Zoltán and Surján, Orsolya and Rákóczi, Éva and Szamosi, Szilvia and Szűcs, Gabriella and Szekanecz, Éva and Müller, Cecília and Kiss, Zoltán},
	doi = {10.3389/fimmu.2023.1247129},
	journal-iso = {FRONT IMMUNOL},
	journal = {FRONTIERS IN IMMUNOLOGY},
	volume = {14},
	unique-id = {34250233},
	issn = {1664-3224},
	abstract = {Introduction
		In Hungary, the HUN-VE 3 study determined the comparative effectiveness of various primary and booster vaccination strategies during the Delta COVID-19 wave. That study included more than 8 million 18-100-year-old individuals from the beginning of the pandemic. Immunocompromised (IC) individuals have increased risk for COVID-19 and disease course might be more severe in them. In this study, we wished to estimate the risk of SARS-CoV-2 infection and COVID-19 related death in IC individuals compared to healthy ones and the effectiveness of the BNT162b2 vaccine by reassessing HUN-VE 3 data.
		Patients and methods
		Among the 8,087,988 individuals undergoing follow-up from the onset of the pandemic in the HUN-VE 3 cohort, we selected all the 263,116 patients with a diagnosis corresponding with IC and 6,128,518 controls from the second wave, before vaccinations started. The IC state was defined as two occurrences of corresponding ICD-10 codes in outpatient or inpatient claims data since 1 January, 2013. The control group included patients without chronic diseases. The data about vaccination, SARS-CoV-2 infection and COVID-19 related death were obtained from the National Public Health Center (NPHC) during the Delta wave. Cases of SARS-CoV-2 infection were reported on a daily basis using a centralized system via the National Public Health Center (NPHC).
		Results
		Out of the 263,116 IC patients 12,055 patients (4.58%) and out of the 6,128,518 healthy controls 202,163 (3.30%) acquired SARS-CoV-2 infection. Altogether 436 IC patients and 2141 healthy controls died in relation to COVID-19. The crude incidence rate ratio (IRR) of SARS-CoV-2 infection was 1.40 (95%CI: 1.37-1.42) comparing IC patients to healthy controls. The crude mortality rate ratio was 4.75 (95%CI: 4.28-5.27). With respect to SARS-CoV-2 infection, interestingly, the BNT162b2 vaccine was more effective in IC patients compared to controls. Primary vaccine effectiveness (VE) was higher in IC patients compared to controls and the booster restored VE after waning. VE regarding COVID-19 related death was less in IC patients compared to healthy individuals. Booster vaccination increased VE against COVID-19-related death in both IC patients and healthy controls.
		Conclusion
		There is increased risk of SARS-CoV-2 infection and COVID-19 related mortality in IC patient. Moreover, booster vaccination using BNT162b2 might restore impaired VE in these individuals.},
	year = {2023},
	eissn = {1664-3224},
	orcid-numbers = {Vokó, Zoltán/0000-0002-1004-1848; Kiss, Zoltán/0000-0002-4752-8529}
}

@article{MTMT:34227615,
	title = {Riociguat in patients with early diffuse cutaneous systemic sclerosis (RISE-SSc): open-label, long-term extension of a phase 2b, randomised, placebo-controlled trial},
	url = {https://m2.mtmt.hu/api/publication/34227615},
	author = {Distler, O. and Allanore, Y. and Denton, C.P. and Kuwana, M. and Matucci-Cerinic, M. and Pope, J.E. and Atsumi, T. and Bečvář, R. and Czirják, László and Hachulla, E. and Ishii, T. and Ishikawa, O. and Johnson, S.R. and De, Langhe E. and Stagnaro, C. and Riccieri, V. and Schiopu, E. and Silver, R.M. and Smith, V. and Steen, V. and Stevens, W. and Szűcs, Gabriella and Truchetet, M.-E. and Wosnitza, M. and Laapas, K. and Kramer, F. and Khanna, D.},
	doi = {10.1016/S2665-9913(23)00238-2},
	journal-iso = {LANCET RHEUMAT},
	journal = {LANCET RHEUMATOL},
	volume = {5},
	unique-id = {34227615},
	issn = {2665-9913},
	year = {2023},
	eissn = {2665-9913},
	pages = {e660-e669}
}

@article{MTMT:34215318,
	title = {Effects of 1-year tofacitinib therapy on angiogenic biomarkers in rheumatoid arthritis},
	url = {https://m2.mtmt.hu/api/publication/34215318},
	author = {Kerekes, György and Czókolyová, Monika and Hamar, Attila and Karancsiné Pusztai, Anita and Tajti, Gábor and Katkó, Mónika and Végh, Edit and Pethő, Zsófia and Bodnár, Nóra and Horváth, Ágnes and Soós, Boglárka and Szamosi, Szilvia and Hascsi, Zsolt and Harangi, Mariann and Hodosi, Katalin and Panyi, György and Seres, Tamás and Szűcs, Gabriella and Szekanecz, Zoltán},
	doi = {10.1093/rheumatology/kead502},
	journal-iso = {RHEUMATOLOGY},
	journal = {RHEUMATOLOGY (UNITED KINGDOM)},
	volume = {62},
	unique-id = {34215318},
	issn = {1462-0324},
	year = {2023},
	eissn = {1462-0332},
	pages = {SI304-SI312},
	orcid-numbers = {Panyi, György/0000-0001-6227-3301}
}