@CONFERENCE{MTMT:36176779,
	title = {The impact of global megatrends on microfungi in the Pannonian Biogeographical Region: a climate change perspective},
	url = {https://m2.mtmt.hu/api/publication/36176779},
	author = {Donát, Magyar and Tischner, Zsófia Bernadett and Anna, Páldy and Kocsubé, Sándor and Zsuzsanna, Dancsházy and Ágnes, Halász and Kredics, László},
	booktitle = {II. Natural Hazards and Climate Change Conference: International Conference for identifying and tackling challenges together},
	unique-id = {36176779},
	year = {2025},
	pages = {11-11},
	orcid-numbers = {Kocsubé, Sándor/0000-0001-7839-0510; Kredics, László/0000-0002-8837-3973}
}

@CONFERENCE{MTMT:36177019,
	title = {Development of casing materials used in white button mushroom cultivation by composting of spent mushroom compost},
	url = {https://m2.mtmt.hu/api/publication/36177019},
	author = {Misz, András and Amanda, Sándorné Szőke and Bajzát, Judit and Dániel, Kökény and Marianna, Visnyei and Kredics, László and Allaga, Henrietta and Kocsubé, Sándor and Vágvölgyi, Csaba and Csutorás, Csaba},
	booktitle = {22nd Wellmann International Scientific Conference : Book of abstracts},
	unique-id = {36177019},
	year = {2025},
	pages = {75-75},
	orcid-numbers = {Kredics, László/0000-0002-8837-3973; Kocsubé, Sándor/0000-0001-7839-0510; Vágvölgyi, Csaba/0000-0003-0009-7773}
}

@article{MTMT:36279134,
	title = {Novel peptaibiotics identified from Trichoderma clade Viride},
	url = {https://m2.mtmt.hu/api/publication/36279134},
	author = {Marik, Tamás and Gufu, Bonaya and Vishwanathula, Anusha and Balázs, Dóra Krisztina and Rozsnyói, Ákos and Terna, Gergő and Kovács, Fanni and Kocsubé, Sándor and Varga, Mónika and Szekeres, András and Druzhinina, Irina S. and Vágvölgyi, Csaba and Papp, Tamás and Tyagi, Chetna and Kredics, László},
	doi = {10.1007/s13659-025-00524-9},
	journal-iso = {NATURAL PRODUCTS AND BIOPROSPECTING},
	journal = {NATURAL PRODUCTS AND BIOPROSPECTING},
	volume = {15},
	unique-id = {36279134},
	issn = {2192-2195},
	abstract = {This study focuses on the peptaibiome produced by different species of Trichoderma belonging to clade Viride : T. koningii SZMC 28387 (CBS 979.70), T. cf . strigosellum SZMC 28007 (TUCIM 4886/IQ 191), T. cf . dorothopsis SZMC 28390 (TUCIM 416/TUB F-597), T. cf . strigosellum SZMC 28391 (TUCIM 423/DAOM 230018), T. atroviride SZMC 28748 (IMI 206040), T. hamatum SZMC 28747 (TUCIM 2730) and T. cf . dorothopsis SZMC 28005 (TUCIM 4882/IQ 11). We were able to identify new compounds with similarity to already known groups of peptaibiotics, as well as completely newly discovered compounds using high-performance liquid chromatography (HPLC) -mass spectrometry (MS). From the 367 peptaibiotics identified, 216 are peptaibols and 111 are lipopeptaibols. Out of all peptaibols, 55 are previously known, while 161 are newly discovered. The new peptaibol subgroups Strigosellin A, B and Dorothopsin A, B are introduced. Furthermore, besides 38 previously known lipopeptaibols, 73 new lipopeptaibol sequences, named Lipostrigosellins and Lipohamatins are also reported. In addition, 41 peptaibol-like compounds with unusual C-terminus were also found. Out of the 7 strains examined, 5 produced both peptaibols and lipopeptaibols, while 2 only peptaibols. The well-known compound, Trikoningin KA V (TRK-V) also produced by T. koningii SZMC 28387 (CBS 979.70), was studied for its folding dynamics using accelerated molecular dynamics simulations (aMD) for understanding the plausible three-dimensional structures adopted by these peptaibols of clade Viride . We observed a propensity to form kinked, right-handed helical structures when simulated in an aqueous environment.},
	year = {2025},
	eissn = {2192-2209},
	orcid-numbers = {Marik, Tamás/0000-0002-0434-5685; Balázs, Dóra Krisztina/0009-0005-3295-9851; Kocsubé, Sándor/0000-0001-7839-0510; Szekeres, András/0000-0003-1651-4623; Vágvölgyi, Csaba/0000-0003-0009-7773; Papp, Tamás/0000-0001-8211-5431; Tyagi, Chetna/0000-0001-7067-4770; Kredics, László/0000-0002-8837-3973}
}

@article{MTMT:36281577,
	title = {A non-canonical fungal peroxisome PTS-1 signal, SYM, and its evolutionary aspects},
	url = {https://m2.mtmt.hu/api/publication/36281577},
	author = {Ámon, Judit and Nemuuzaya, Suren and Alczheimer, Kevin and Kocsubé, Sándor and Farkas, Zoltán and Svorenj, Gergő and Gácser, Attila and Tyagi, Chetna and Kozma-Bognár, László and Kozma-Bognárné Hamari, Zsuzsanna},
	doi = {10.1038/s41598-025-13871-x},
	journal-iso = {SCI REP},
	journal = {SCIENTIFIC REPORTS},
	volume = {15},
	unique-id = {36281577},
	abstract = {Proteins localized to peroxisomes, particularly those expressed under specific conditions or in low abundance, are often undetected by routine proteomics methods due to detection sensitivity limits. In silico identification and experimental validation of peroxisomal targeting signals (PTSs) offer a reliable alternative. We demonstrate that SYM, a non-canonical plant PTS-1 signal, functions similarly in Aspergillus nidulans , as GFP tagged with a SYM C-terminal tripeptide localizes to peroxisomes. One of two native A. nidulans proteins with C-terminal SYM tripeptide shows weak peroxisomal localization alongside cytoplasmic presence, indicating that only a subset of proteins with non-canonical signals access peroxisomes. In silico analysis of 1,010 fungal genomes identified diverse SYM-proteins with variable functions, suggesting that non-canonical PTS-1 signals may evolve spontaneously. Two-thirds of SYM-proteins are predicted to localize to specific intracellular compartments other than the peroxisome. We propose that despite their predicted localization, these proteins possessing SYM as a non-canonical peroxisomal signal might also have peroxisomal presence. Among SYM-proteins, pectinesterases, known plant pathogen virulence factors, were frequent. Notably, 25% of fungal pectinesterases harbor non-canonical PTS-1 signals, suggesting that partial peroxisomal localization of pectinesterases has evolved convergently. This suggests that partial peroxisomal localization may enhance protein functional flexibility, contributing to the organism’s adaptability.},
	year = {2025},
	eissn = {2045-2322},
	orcid-numbers = {Ámon, Judit/0000-0002-3234-6167; Kocsubé, Sándor/0000-0001-7839-0510; Tyagi, Chetna/0000-0001-7067-4770; Kozma-Bognár, László/0000-0002-8289-193X; Kozma-Bognárné Hamari, Zsuzsanna/0000-0001-6374-5083}
}

@article{MTMT:36297827,
	title = {Role of the putative sit1 gene in normal germination of spores and virulence of the Mucor lusitanicus},
	url = {https://m2.mtmt.hu/api/publication/36297827},
	author = {Vágó, Bernadett and Bauer, Kitti and Varghese, Naomi and Kiss-Vetráb, Sándor and Kocsubé, Sándor and Varga, Mónika and Szekeres, András and Vágvölgyi, Csaba and Papp, Tamás and Nagy, Gábor},
	doi = {10.15698/mic2025.08.856},
	journal-iso = {MICROBIAL CELL},
	journal = {MICROBIAL CELL},
	volume = {12},
	unique-id = {36297827},
	issn = {2311-2638},
	abstract = {Mucormycosis is a life-threatening infection caused by certain members of the fungal order Mucorales, with increased incidence in recent years. Individuals with untreated diabetes mellitus, and patients treated with deferoxamine are particularly susceptible to this infection. Elevated free iron concentrations in serum contribute to the development of mucormycosis. Pathogenic fungi have evolved multiple mechanisms to acquire and utilize free iron or extract it from the various iron-binding molecules within the host. The utilization of hydroxamate siderophores as xenosiderophores may contribute to the development of mucormycosis. The genome of Mucor lusitanicus encodes one Sit1 siderophore transporter. In this study, the role of the sit1 gene was characterized by generating knockout mutants using CRISPR-Cas9. Relative transcript level of the sit1 gene significantly increased in the presence of deferoxamine- and deferasirox-iron complexes. Lack of sit1 resulted in altered germination of spores and growth ability, and decreased virulence. Furthermore, absence of the gene caused elevated transcript levels of a ferric reductase (FRE), a low-affinity iron permease (FET4) and a copper dependent iron oxidase (FET3). Our result suggests that expressions of the genes involved in iron uptake affect each other. The lack of Sit1 resulted in an increased transcript level of the FRE3 gene, which may be able to reduce iron from the siderophore-iron complex. The reduced and liberated iron may be then taken up by activated FET4a. This study highlights the significance of understanding the iron acquisition mechanisms of pathogenic fungi to develop effective treatments for fungal infections.},
	year = {2025},
	eissn = {2311-2638},
	pages = {195-209},
	orcid-numbers = {Varghese, Naomi/0009-0000-7049-8279; Kocsubé, Sándor/0000-0001-7839-0510; Szekeres, András/0000-0003-1651-4623; Vágvölgyi, Csaba/0000-0003-0009-7773; Papp, Tamás/0000-0001-8211-5431; Nagy, Gábor/0000-0002-7871-6098}
}

@article{MTMT:36328243,
	title = {Bacterial Cellulose Production in Co-Culture Systems: Opportunities, Challenges, and Future Directions},
	url = {https://m2.mtmt.hu/api/publication/36328243},
	author = {Absharina, Dheanda and Putra, Filemon Jalu Nusantara and Ogino, Chiaki and Kocsubé, Sándor and Veres, Csilla and Vágvölgyi, Csaba},
	doi = {10.3390/applmicrobiol5030092},
	journal-iso = {APPL MICROBIOL},
	journal = {APPLIED MICROBIOLOGY},
	volume = {5},
	unique-id = {36328243},
	abstract = {Bacterial cellulose (BC), a nanostructured biopolymer produced by Komagateibacter spp., exhibits remarkable mechanical strength, purity, and biocompatibility, making it highly attractive for applications in biomedicine, food, and sustainable materials. Despite its potential, monoculture fermentation suffers from low yield and limited scalability. This review highlights the innovative application of co-culture fermentations as a novel strategy, where Komagataeibacter is paired with complementary microorganisms such as yeasts, lactic acid bacteria, and photosynthetic microbes. This approach has emerged as a promising solution to overcome the limitations of monoculture by enhancing BC productivity, tailoring material properties, and improving sustainability. We explore the synergistic interactions within co-cultures, including metabolic cross-feeding and in situ polymer integration, while also addressing critical challenges such as microbial stability and operational complexity. Unlike previous reviews focused primarily on BC biosynthesis, applications, or genetic engineering, this article emphasizes co-culture fermentation with Komagataeibacter as a novel and underexplored strategy to improve the yield, functionality, and scalability of BC production.},
	year = {2025},
	eissn = {2673-8007},
	orcid-numbers = {Absharina, Dheanda/0000-0001-6418-3414; Kocsubé, Sándor/0000-0001-7839-0510; Vágvölgyi, Csaba/0000-0003-0009-7773}
}

@CONFERENCE{MTMT:36410534,
	title = {Virulence-associated traits in Mucor lusitanicus},
	url = {https://m2.mtmt.hu/api/publication/36410534},
	author = {Szebenyi, Csilla and Kocsubé, Sándor and Molnár, Anna and Kiss, Karina and Sinka, Rita and Németh, Dóra and Szegedi, Botond Ferenc and Abu Saleem, Tammam Khaliefeh Siliman and Vágvölgyi, Csaba and Papp, Tamás},
	booktitle = {ABSTRACTS of the 7th Central European Forum for Microbiology},
	unique-id = {36410534},
	year = {2025},
	pages = {74-74},
	orcid-numbers = {Kocsubé, Sándor/0000-0001-7839-0510; Vágvölgyi, Csaba/0000-0003-0009-7773; Papp, Tamás/0000-0001-8211-5431}
}

@article{MTMT:34682151,
	title = {An ascomycete H4 variant with an unknown function},
	url = {https://m2.mtmt.hu/api/publication/34682151},
	author = {Flipphi, Michel Johannes Anthonie and Harispe, María Laura and Kozma-Bognárné Hamari, Zsuzsanna and Kocsubé, Sándor and Scazzocchio, Claudio and Ramón, Ana},
	doi = {10.1098/rsos.231705},
	journal-iso = {R SOC OPEN SCI},
	journal = {ROYAL SOCIETY OPEN SCIENCE},
	volume = {11},
	unique-id = {34682151},
	abstract = {Histone variants leading to altered nucleosome structure, dynamics and DNA accessibility occur frequently, albeit rarely for H4. We carried out a comprehensive in silico scrutiny of fungal genomes, which revealed the presence of a novel H4 variant (H4E) in the ascomycetes, throughout the Pezizomycotina, in basal species of the Taphrinomycotina and also in the Glomeromycota. The coding cognate genes show a specific intron/exon organization, different from H4 canonical genes. H4Es diverge from canonical H4s mainly in the N- and C-terminal extensions, showing marked differences in the distribution and number of Lys and Arg residues, which may result in novel post-translational modifications. In Aspergillus nidulans (Pezizomycotina, Eurotiomycetes) the H4E variant protein level is low in mycelia. However, the encoding gene is well expressed at 37°C under nitrogen starvation. H4E localizes to the nucleus and interacts with H3, but its absence or overexpression does not result in any detectable phenotype. Deletion of only one of the of the two canonical H4 genes results in a strikingly impaired growth phenotype, which indicates that H4E cannot replace this canonical histone. Thus, an H4 variant is present throughout a whole subphylum of the ascomycetes, but with hitherto no experimentally detectable function.},
	year = {2024},
	eissn = {2054-5703},
	orcid-numbers = {Kozma-Bognárné Hamari, Zsuzsanna/0000-0001-6374-5083; Kocsubé, Sándor/0000-0001-7839-0510}
}

@CONFERENCE{MTMT:34723140,
	title = {A Sit1 sziderofór transzporter szerepe Mucor lusitanicusban},
	url = {https://m2.mtmt.hu/api/publication/34723140},
	author = {Vágó, Bernadett and Bauer, Kitti and Kiss-Vetráb, Sándor and Kocsubé, Sándor and Vágvölgyi, Csaba and Papp, Tamás and Nagy, Gábor},
	booktitle = {Biotechnológiai Szakmai Nap Absztraktfüzet},
	unique-id = {34723140},
	year = {2024},
	orcid-numbers = {Kocsubé, Sándor/0000-0001-7839-0510; Vágvölgyi, Csaba/0000-0003-0009-7773; Papp, Tamás/0000-0001-8211-5431; Nagy, Gábor/0000-0002-7871-6098}
}

@article{MTMT:34747961,
	title = {A review of recently introduced Aspergillus, Penicillium, Talaromyces and other Eurotiales species},
	url = {https://m2.mtmt.hu/api/publication/34747961},
	author = {Visagie, C. M. and Yilmaz, N. and Kocsubé, Sándor and Frisvad, J. C. and Hubka, V. and Samson, R. A. and Houbraken, J.},
	doi = {10.3114/sim.2024.107.01},
	journal-iso = {STUD MYCOL},
	journal = {STUDIES IN MYCOLOGY},
	volume = {107},
	unique-id = {34747961},
	issn = {0166-0616},
	abstract = {The order Eurotiales is diverse and includes species that impact our daily lives in many ways. In the past, its taxonomy was difficult due to morphological similarities, which made accurate identification of species difficult. This situation improved and stabilised with recent taxonomic and nomenclatural revisions that modernised Aspergillus, Penicillium and Talaromyces. This was mainly due to the availability of curated accepted species lists and the publication of comprehensive DNA sequence reference datasets. This has also led to a sharp increase in the number of new species described each year with the accepted species lists in turn also needing regular updates. The focus of this study was to review the 160 species described between the last list of accepted species published in 2020 until 31 December 2022. To review these species, single-gene phylogenies were constructed and GCPSR (Genealogical Concordance Phylogenetic Species Recognition) was applied. Multi-gene phylogenetic analyses were performed to further determine the relationships of the newly introduced species. As a result, we accepted 133 species (37 Aspergillus, two Paecilomyces, 59 Penicilium, two Rasamsonia, 32 Talaromyces and one Xerochrysium), synonymised 22, classified four as doubtful and created a new combination for Paraxerochrysium coryli, which is classified in Xerochrysium. This brings the number of accepted species to 453 for Aspergillus, 12 for Paecilomyces, 535 for Penicillium, 14 for Rasamsonia, 203 for Talaromyces and four for Xerochrysium. We accept the newly introduced section Tenues (in Talaromyces), and series Hainanici (in Aspergillus sect. Cavernicolarum) and Vascosobrinhoana (in Penicillium sect. Citrina). In addition, we validate the invalidly described species Aspergillus annui and A. saccharicola, and series Annuorum (in Aspergillus sect. Flavi), introduce a new combination for Dichlaena lentisci (type of the genus) and place it in a new section in Aspergillus subgenus Circumdati, provide an updated description for Rasamsonia oblata, and list excluded and recently synonymised species that were previously accepted. This study represents an important update of the accepted species lists in Eurotiales.},
	keywords = {IDENTIFICATION; Fungi; Aspergillus; nomenclature; nomenclature; Penicillium; New taxa; DNA barcodes; phylogenetic species concept; polyphasic taxonomy; Accepted species list; Aspergilaceae; Penicillaginaceae; Thermoascaceae; WADI-EL-NATRON; PHYLOGENETIC REVISION; SECTION CIRCUMDATI},
	year = {2024},
	eissn = {1872-9797},
	pages = {1-66},
	orcid-numbers = {Kocsubé, Sándor/0000-0001-7839-0510}
}