@misc{MTMT:34125060, title = {Sensory-substitution-based perception interface using spinal cord stimulation applied for hearing aid}, url = {https://m2.mtmt.hu/api/publication/34125060}, author = {Halász, László and Balint, VARKUTI and Gabriella, MIKLOS and Saman, HAGH GOOIE and Tóth, Emília and Max, HASSELBERGER and Gijs, VAN ELSWIJK and Erőss, Loránd}, unique-id = {34125060}, year = {2023}, orcid-numbers = {Erőss, Loránd/0000-0002-5796-5546} } @article{MTMT:34019088, title = {The role of superficial and deep layers in the generation of high frequency oscillations and interictal epileptiform discharges in the human cortex}, url = {https://m2.mtmt.hu/api/publication/34019088}, author = {Fabó, Dániel and Bokodi, Virág and Szabó, Johanna Petra and Tóth, Emília and Salami, Pariya and Keller, Corey J and Hajnal, Boglárka Zsófia and Thesen, Thomas and Devinsky, Orrin and Doyle, Werner and Mehta, Ashesh and Madsen, Joseph and Eskandar, Emad and Erőss, Loránd and Ulbert, István and Halgren, Eric and Cash, Sydney S}, doi = {10.1038/s41598-022-22497-2}, journal-iso = {SCI REP}, journal = {SCIENTIFIC REPORTS}, volume = {13}, unique-id = {34019088}, issn = {2045-2322}, abstract = {Describing intracortical laminar organization of interictal epileptiform discharges (IED) and high frequency oscillations (HFOs), also known as ripples. Defining the frequency limits of slow and fast ripples. We recorded potential gradients with laminar multielectrode arrays (LME) for current source density (CSD) and multi-unit activity (MUA) analysis of interictal epileptiform discharges IEDs and HFOs in the neocortex and mesial temporal lobe of focal epilepsy patients. IEDs were observed in 20/29, while ripples only in 9/29 patients. Ripples were all detected within the seizure onset zone (SOZ). Compared to hippocampal HFOs, neocortical ripples proved to be longer, lower in frequency and amplitude, and presented non-uniform cycles. A subset of ripples (≈ 50%) co-occurred with IEDs, while IEDs were shown to contain variable high-frequency activity, even below HFO detection threshold. The limit between slow and fast ripples was defined at 150 Hz, while IEDs' high frequency components form clusters separated at 185 Hz. CSD analysis of IEDs and ripples revealed an alternating sink-source pair in the supragranular cortical layers, although fast ripple CSD appeared lower and engaged a wider cortical domain than slow ripples MUA analysis suggested a possible role of infragranularly located neural populations in ripple and IED generation. Laminar distribution of peak frequencies derived from HFOs and IEDs, respectively, showed that supragranular layers were dominated by slower (< 150 Hz) components. Our findings suggest that cortical slow ripples are generated primarily in upper layers while fast ripples and associated MUA in deeper layers. The dissociation of macro- and microdomains suggests that microelectrode recordings may be more selective for SOZ-linked ripples. We found a complex interplay between neural activity in the neocortical laminae during ripple and IED formation. We observed a potential leading role of cortical neurons in deeper layers, suggesting a refined utilization of LMEs in SOZ localization.}, year = {2023}, eissn = {2045-2322}, orcid-numbers = {Fabó, Dániel/0000-0001-5141-5351; Szabó, Johanna Petra/0000-0001-7690-9171; Erőss, Loránd/0000-0002-5796-5546; Ulbert, István/0000-0001-9941-9159} } @article{MTMT:33075628, title = {A humán agykéreg elektromos ingerlésével kiváltott válaszok alatti lokális hálózati és egysejt-szintű aktivitásváltozásainak vizsgálata}, url = {https://m2.mtmt.hu/api/publication/33075628}, author = {Hajnal, Boglárka Zsófia and Entz, László and Tóth, Emília and Wittner, Lucia and Ulbert, István and Erőss, Loránd and Fabó, Dániel}, journal-iso = {IDEGGYÓGY SZEMLE PROC}, journal = {IDEGGYÓGYÁSZATI SZEMLE PROCEEDINGS / CLINICAL NEUROSCIENCE PROCEEDINGS}, volume = {7}, unique-id = {33075628}, issn = {2498-6240}, year = {2022}, pages = {18}, orcid-numbers = {Wittner, Lucia/0000-0001-6800-0953; Ulbert, István/0000-0001-9941-9159; Erőss, Loránd/0000-0002-5796-5546; Fabó, Dániel/0000-0001-5141-5351} } @article{MTMT:32548110, title = {Local neuronal network and single unit changes evoked by single and paired pulse cortical stimulation in humans}, url = {https://m2.mtmt.hu/api/publication/32548110}, author = {Hajnal, Boglárka Zsófia and Entz, László and Tóth, Emília and Ulbert, István and Erőss, Loránd and Fabó, Dániel}, journal-iso = {EPILEPSIA}, journal = {EPILEPSIA}, volume = {62}, unique-id = {32548110}, issn = {0013-9580}, year = {2021}, eissn = {1528-1167}, pages = {264-265}, orcid-numbers = {Ulbert, István/0000-0001-9941-9159; Erőss, Loránd/0000-0002-5796-5546; Fabó, Dániel/0000-0001-5141-5351} } @article{MTMT:31794996, title = {Laminar distribution of electrically evoked hippocampal short latency ripple activity highlights the importance of the subiculum in vivo in human epilepsy, an intraoperative study}, url = {https://m2.mtmt.hu/api/publication/31794996}, author = {Tóth, Emília and Bokodi, Virág and Somogyvári, Zoltán and Maglóczky, Zsófia and Wittner, Lucia and Ulbert, István and Erőss, Loránd and Fabó, Dániel}, doi = {10.1016/j.eplepsyres.2020.106509}, journal-iso = {EPILEPSY RES}, journal = {EPILEPSY RESEARCH}, volume = {169}, unique-id = {31794996}, issn = {0920-1211}, year = {2021}, eissn = {1872-6844}, orcid-numbers = {Wittner, Lucia/0000-0001-6800-0953; Ulbert, István/0000-0001-9941-9159; Erőss, Loránd/0000-0002-5796-5546; Fabó, Dániel/0000-0001-5141-5351} } @article{MTMT:32055138, title = {The neocortical neural correlates of electrically evoked cortical potentials in humans}, url = {https://m2.mtmt.hu/api/publication/32055138}, author = {Hajnal, Boglárka Zsófia and Entz, László and Tóth, Emília and Ulbert, István and Fabó, Dániel and Erőss, Loránd}, doi = {10.1016/j.clinph.2019.04.550}, journal-iso = {CLIN NEUROPHYSIOL}, journal = {CLINICAL NEUROPHYSIOLOGY}, volume = {130}, unique-id = {32055138}, issn = {1388-2457}, year = {2019}, eissn = {1872-8952}, pages = {e97}, orcid-numbers = {Ulbert, István/0000-0001-9941-9159; Fabó, Dániel/0000-0001-5141-5351; Erőss, Loránd/0000-0002-5796-5546} } @inproceedings{MTMT:30401320, title = {Synergism of spectral and coupling modalities in epileptic focus localization from iEEG recordings}, url = {https://m2.mtmt.hu/api/publication/30401320}, author = {Nánási, Tibor and File, Bálint and Tóth, Emília and Entz, László and Ulbert, István and Fabó, Dániel and Erőss, Loránd}, booktitle = {6th International Workshop on Pattern Recognition in Neuroimaging, PRNI 2016}, doi = {10.1109/PRNI.2016.7552354}, unique-id = {30401320}, year = {2016}, pages = {113-116}, orcid-numbers = {Ulbert, István/0000-0001-9941-9159; Fabó, Dániel/0000-0001-5141-5351; Erőss, Loránd/0000-0002-5796-5546} } @mastersthesis{MTMT:3094852, title = {Development of multimodal diagnostic tools for epilepsy patients implanted with intracranial micro- and macroelectrodes}, url = {https://m2.mtmt.hu/api/publication/3094852}, author = {Tóth, Emília}, doi = {10.15774/PPKE.ITK.2016.004}, publisher = {PPKE}, unique-id = {3094852}, year = {2016} } @CONFERENCE{MTMT:3015752, title = {High frequency oscillations in the human hippocampal formation using single pulse cortical electrical stimulation [poster]}, url = {https://m2.mtmt.hu/api/publication/3015752}, author = {Bokodi, Virág and Tóth, Emília and Somogyvári, Zoltán and Maglóczky, Zsófia and Erőss, Loránd and Ulbert, István and Fabó, Dániel}, booktitle = {IBRO Workshop 2016}, unique-id = {3015752}, year = {2016}, orcid-numbers = {Erőss, Loránd/0000-0002-5796-5546; Ulbert, István/0000-0001-9941-9159; Fabó, Dániel/0000-0001-5141-5351} } @article{MTMT:3015678, title = {Intracranial neuronal ensemble recordings and analysis in epilepsy.}, url = {https://m2.mtmt.hu/api/publication/3015678}, author = {Tóth, Emília and Fabó, Dániel and Entz, László and Ulbert, István and Erőss, Loránd}, doi = {10.1016/j.jneumeth.2015.09.028}, journal-iso = {J NEUROSCI METH}, journal = {JOURNAL OF NEUROSCIENCE METHODS}, volume = {260}, unique-id = {3015678}, issn = {0165-0270}, abstract = {Pathological neuronal firing was demonstrated 50 years ago as the hallmark of epileptically transformed cortex with the use of implanted microelectrodes. Since then, microelectrodes remained only experimental tools in humans to detect unitary neuronal activity to reveal physiological and pathological brain functions. This recording technique has evolved substantially in the past few decades; however, based on recent human data implying their usefulness as diagnostic tools, we expect a substantial increase in the development of microelectrodes in the near future. Here, we review the technological background and history of microelectrode array development for human examinations in epilepsy, including discussions on of wire-based and microelectrode arrays fabricated using micro-electro-mechanical system (MEMS) techniques and novel future techniques to record neuronal ensemble. We give an overview of clinical and surgical considerations, and try to provide a list of probes on the market with their availability for human recording. Then finally, we briefly review the literature on modulation of single neuron for the treatment of epilepsy, and highlight the current topics under examination that can be background for the future development.}, year = {2016}, eissn = {1872-678X}, pages = {261-269}, orcid-numbers = {Fabó, Dániel/0000-0001-5141-5351; Ulbert, István/0000-0001-9941-9159; Erőss, Loránd/0000-0002-5796-5546} }