@{MTMT:34598593, title = {Effect of drying process on the physico-chemical properties of oxicam drugs}, url = {https://m2.mtmt.hu/api/publication/34598593}, author = {Gamiel, Alaa and Bartos, Csilla and Ambrus, Rita}, booktitle = {VI. Symposium of Young Researchers on Pharmaceutical Technology, Biotechnology and Regulatory Science}, doi = {10.14232/syrptbrs.2024.56}, unique-id = {34598593}, year = {2024}, pages = {56-57} } @article{MTMT:34066497, title = {Preparation and Characterization of Smartcrystals for Dissolution Enhancement of Poorly Water - Soluble Niflumic Acid}, url = {https://m2.mtmt.hu/api/publication/34066497}, author = {Alshweiat, Areen and Varga, Patrícia Orsolya and Pannonhalminé Csóka, Ildikó and Motzwickler-Németh, Anett and Bartos, Csilla and Ambrus, Rita}, doi = {10.31925/farmacia.2023.3.7}, journal-iso = {FARMACIA}, journal = {FARMACIA (BUCHAREST)}, volume = {71}, unique-id = {34066497}, issn = {0014-8237}, year = {2023}, eissn = {2065-0019}, pages = {501-510}, orcid-numbers = {Alshweiat, Areen/0000-0001-7008-0972; Pannonhalminé Csóka, Ildikó/0000-0003-0807-2781} } @{MTMT:34066446, title = {Meloxikám-kálium tartalmú nazális porok stabilitásvizsgálata}, url = {https://m2.mtmt.hu/api/publication/34066446}, author = {Varga, Patrícia Orsolya and Bartos, Csilla and Ambrus, Rita}, booktitle = {XXVI. Tavaszi Szél Konferencia 2023 : Absztrakt kötet}, unique-id = {34066446}, year = {2023}, pages = {359-359} } @article{MTMT:33573245, title = {Nano-Spray-Dried Levocetirizine Dihydrochloride with Mucoadhesive Carriers and Cyclodextrins for Nasal Administration}, url = {https://m2.mtmt.hu/api/publication/33573245}, author = {Mirankó, Mirella and Tóth, Judit and Bartos, Csilla and Ambrus, Rita and Feczkó, Tivadar}, doi = {10.3390/pharmaceutics15020317}, journal-iso = {PHARMACEUTICS}, journal = {PHARMACEUTICS}, volume = {15}, unique-id = {33573245}, issn = {1999-4923}, abstract = {Antihistamines such as levocetirizine dihydrochloride (LC) are commercially used in oral tablets and oral drops to reduce allergic symptoms. In this study, LC was nano-spray-dried using three mucoadhesive polymers and four cyclodextrin species to form composite powders for nasal administration. The product was composed of hydroxypropyl methylcellulose polymer, including LC as a zwitterion, after neutralization by NaOH, and XRD investigations verified its amorphous state. This and a sulfobutylated-beta-cyclodextrin sodium salt-containing sample showed crystal peaks due to NaCl content as products of the neutralization reaction in the solutions before drying. The average particle size of the spherical microparticles was between 2.42 and 3.44 µm, except for those containing a polyvinyl alcohol excipient, which were characterized by a medium diameter of 29.80 µm. The drug was completely and immediately liberated from all the samples at pH 5.6 and 32 °C; i.e., the carriers did not change the good dissolution behavior of LC. A permeability test was carried out by dipping the synthetic cellulose ester membrane in isopropyl myristate using modified horizontal diffusion cells. The spray-dried powder with β-cyclodextrin showed the highest permeability (188.37 µg/cm2/h), as this additive was the least hydrophilic. Products prepared with other cyclodextrins (randomly methylated-beta-cyclodextrin, sulfobutylated-beta-cyclodextrin sodium salt and (hydroxypropyl)-beta-cyclodextrin) showed similar or slightly higher penetration abilities than LC. Other polymer excipients resulted in lower penetration of the active agent than the pure LC.}, year = {2023}, eissn = {1999-4923}, orcid-numbers = {Ambrus, Rita/0000-0001-5496-1710} } @article{MTMT:33562140, title = {The Effect of the Particle Size Reduction on the Biorelevant Solubility and Dissolution of Poorly Soluble Drugs with Different Acid-Base Character}, url = {https://m2.mtmt.hu/api/publication/33562140}, author = {Csicsák, Dóra and Szolláth, Rita Mariann and Kádár, Szabina and Ambrus, Rita and Bartos, Csilla and Bertalanné Balogh, Emese and Antal, István and Köteles, István and Tőzsér, Petra and Bárdos, Vivien and Horváth, Péter and Borbás, Enikő and Takácsné Novák, Krisztina and Sinkó, B. and Völgyi, Gergely}, doi = {10.3390/pharmaceutics15010278}, journal-iso = {PHARMACEUTICS}, journal = {PHARMACEUTICS}, volume = {15}, unique-id = {33562140}, issn = {1999-4923}, year = {2023}, eissn = {1999-4923}, orcid-numbers = {Csicsák, Dóra/0000-0003-3663-3566; Szolláth, Rita Mariann/0000-0003-2846-7676; Bertalanné Balogh, Emese/0000-0002-1127-3923; Antal, István/0000-0002-5434-201X; Köteles, István/0000-0002-1678-233X; Bárdos, Vivien/0000-0003-4622-9380; Horváth, Péter/0000-0001-7149-4173; Takácsné Novák, Krisztina/0000-0002-4467-1143; Völgyi, Gergely/0000-0001-8990-3916} } @CONFERENCE{MTMT:33231423, title = {Nifluminsav nanokristályok előállítása és vizsgálata}, url = {https://m2.mtmt.hu/api/publication/33231423}, author = {Varga, Patrícia Orsolya and Alshweiat, Areen and Pannonhalminé Csóka, Ildikó and Révész, Piroska and Bartos, Csilla and Ambrus, Rita}, booktitle = {Gyógyszertechnológiai és Ipari Gyógyszerészeti Konferencia 2022: A Magyar Gyógyszerésztudományi Társaság Gyógyszeripari Szervezetének és Gyógyszertechnológiai Szakosztályának Konferenciája}, unique-id = {33231423}, year = {2022}, orcid-numbers = {Alshweiat, Areen/0000-0001-7008-0972; Pannonhalminé Csóka, Ildikó/0000-0003-0807-2781; Révész, Piroska/0000-0002-5336-6052} } @{MTMT:33231285, title = {Investigation Of Meloxicam Potassium Containing Nanoparticles For Intranasal Administration}, url = {https://m2.mtmt.hu/api/publication/33231285}, author = {Varga, Patrícia Orsolya and Bartos, Csilla and Ambrus, Rita}, booktitle = {9th BBBB International Conference on Pharmaceutical Sciences - Pharma Sciences of Tomorrow: Book of Abstracts}, unique-id = {33231285}, year = {2022}, pages = {247-248} } @{MTMT:32868295, title = {Preparation and investigation of meloxicam potassium containing cyclodextrin nanoparticles intended for nasal application}, url = {https://m2.mtmt.hu/api/publication/32868295}, author = {Varga, Patrícia Orsolya and Ambrus, Rita and Révész, Piroska and Kókai, Dávid and Burián, Katalin and Bella, Zsolt and Fenyvesi, Ferenc and Bartos, Csilla}, booktitle = {IV. Symposium of Young Researchers on Pharmaceutical Technology, Biotechnology and Regulatory Science : book of abstracts}, doi = {10.14232/syrptbrs.2022.32}, unique-id = {32868295}, year = {2022}, pages = {32-32}, orcid-numbers = {Révész, Piroska/0000-0002-5336-6052; Burián, Katalin/0000-0003-1300-2374; Fenyvesi, Ferenc/0000-0003-2890-0783} } @article{MTMT:32613774, title = {Smartcrystals for Efficient Dissolution of Poorly Water-Soluble Meloxicam}, url = {https://m2.mtmt.hu/api/publication/32613774}, author = {Ambrus, Rita and Alshweiat, Areen and Révész, Piroska and Bartos, Csilla and Pannonhalminé Csóka, Ildikó}, doi = {10.3390/pharmaceutics14020245}, journal-iso = {PHARMACEUTICS}, journal = {PHARMACEUTICS}, volume = {14}, unique-id = {32613774}, issn = {1999-4923}, year = {2022}, eissn = {1999-4923}, orcid-numbers = {Alshweiat, Areen/0000-0001-7008-0972; Révész, Piroska/0000-0002-5336-6052; Pannonhalminé Csóka, Ildikó/0000-0003-0807-2781} } @CONFERENCE{MTMT:32900458, title = {Nazális bevitel céljából előállított meloxikám-kálium tartalmú nanoszférák vizsgálata}, url = {https://m2.mtmt.hu/api/publication/32900458}, author = {Varga, Patrícia Orsolya and Ambrus, Rita and Bartos, Csilla}, booktitle = {MKE Kristályosítási és Gyógyszerformulálási Szakosztály 13. Kerekasztal Konferenciája}, unique-id = {32900458}, year = {2021}, pages = {24-25} }